2026 May - 107 articles
The consumption of wild rodents in certain regions of Southwest China creates a potential interface for zoonotic pathogen exposure, yet the virome composition of edible rodents remains insufficiently characterized. In this study, we performed multi-o...
Cystic fibrosis (CF) lung disease is characterized by chronic infection and progressive airway damage, driven by interactions between epithelial dysfunction, immune dysregulation, and microbial adaptation. Defective cystic fibrosis transmembrane cond...
Background: Klebsiella pneumoniae is a globally relevant pathogen whose growing association between hypervirulence and antimicrobial resistance represents a major public health challenge. Methods: A systematic review was performed following the PRISM...
Primary Epstein–Barr virus (EBV) infection in children exhibits substantial clinical heterogeneity, often complicating early diagnosis and leading to unnecessary antibiotic use. This retrospective study evaluated 695 children (0–18 years)...
Human T-cell leukemia virus-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic inflammatory disease of the spinal cord induced by immunological activation due to high HTLV-1 proviral load in the peripheral blood. HAM...
Objective: Our objective was to investigate the association between serum phosphorus levels and 28-day mortality in patients with bloodstream infection (BSI), and to explore whether this association persists after adjusting for renal function and cli...
Yak diarrhea is a major health concern in high-altitude regions, yet data are lacking in Ganzi Tibetan Autonomous Prefecture, a key yak-producing area in China. This study aimed to describe the prevalence, mortality, seasonal patterns, and pathogen p...
This review provides a comprehensive overview of the genetic diversity and epidemiological potential of Yersinia pestis in Kazakhstan’s natural plague foci, emphasizing the link between genotypic variation and outbreak capacity. Integrating his...
Helminth infections remain a major constraint to livestock productivity, particularly in regions where domestic animals and wildlife share grazing habitats. This study investigated the molecular diversity and transmission dynamics of helminth communi...
Hepatitis E is a liver inflammation caused by the hepatitis E virus (HEV). In pregnant women, the infection significantly increases the risk of acute liver failure, fetal loss, and maternal death. According to the World Health Organization, infection...
Inflammatory bowel disease (IBD) is a chronic inflammatory condition resulting from complex interactions between the immune system, genetic predisposition, and the gut microbiota. In this context, Escherichia coli (E. coli) plays a dual role in the h...
This study examined the distribution and seasonal population dynamics of tick species infesting cattle, sheep, and goats in Ağrı Province, Türkiye. From January to December 2024, 913 hosts were examined, and 545 intact tick samples wer...
This retrospective study evaluated the prevalence and economic impact of tuberculosis-likelesions (TB) in cattle, sheep, and goats slaughtered at municipal abattoirs in the provinces of Bejaia and Jijel between 2019 and 2024, and examined their ecolo...
Leishmaniasis remains a major neglected tropical disease with limited therapeutic options, challenged by drug toxicity and emerging resistance to current treatments like miltefosine. In this study, a virtual library of approximately 150 azole-derived...
Recently, a strain of Streptococcus agalactiae serotype Ia sequence type 7 clonal complex 1 (SaIa ST7 CC1) has emerged in Latin American tilapia aquaculture as an international threat. This study evaluated outbreaks of acute streptococcosis occurring...
Why do pandemics keep emerging despite decades of surveillance and response? Paleopathology, the study of disease traces in ancient remains, has been revolutionized by ancient DNA (aDNA) analysis and next-generation sequencing (NGS). Reconstructing p...
Coxiella burnetii is an intracellular bacterium responsible for an anthropozoonosis that can be asymptomatic or manifest as acute or chronic Q fever. This extensive series of 588 patients represents one of the largest single-center studies on sporadi...
Olfactory dysfunction (OD) is a common sequela of SARS-CoV-2 infection, but its prevalence and associated factors beyond 2 years remain unclear. In this multicenter observational study, we assessed 155 recovered COVID-19 patients approximately three...
Characterizing the specific interactions of Leishmania species with different host systems is essential for the development and validation of experimental infection models and for identifying potential therapeutic targets. Leishmania parasites elicit...
This study used three complementary datasets to investigate the relationship between human Campylobacter infections in Estonia and potential sources. A targeted dataset of 15 C. jejuni genomes with overlapping sequence types from human cases and broi...
Candida species, particularly Candida albicans (C. albicans), are the leading cause of vulvovaginal candidosis (VVC) among women of reproductive age. In recent years, the epidemiology of VVC has shifted toward non-albicans Candida (NAC) species, acco...
Cervical cancer screening with high-risk human papillomavirus (HR-HPV) testing requires effective triage of HPV-positive women. Koilocytosis is a classic cytopathic effect of HPV infection, but its clinical significance in low-grade squamous intraepi...
Schistosomiasis (bilharzia) is a parasitic infection caused by trematodes of the Schistosoma genus and remains a significant health burden in endemic regions. Granulomatous host responses to deposited Schistosoma eggs in small veins and tissues resul...
Tick-borne encephalitis virus (TBEV) is a major arthropod-borne flavivirus responsible for severe neurological disease in humans across Europe and Asia. It is maintained in nature through complex interactions within ticks and between tick vectors, ve...
Schistosomiasis, a neglected tropical disease (NTD), affects humans and leads to considerable clinical morbidity and severe long-term sequelae. Laboratory diagnostics for Schistosoma mansoni are mainly based on microscopic identification of eggs in s...
Microbiological culture and histology of deep tissue specimens are independent diagnostic criteria in fracture-related infection (FRI). However, the association between these tests has rarely been investigated, particularly in relation to clinical ou...
Post-infectious bronchiolitis obliterans (PIBO) is a severe chronic airway disease in children following lower respiratory tract infections. Human adenovirus (HAdV) and Mycoplasma pneumoniae (MP) are the major associated pathogens, with geographic va...
Background: In some children with immunodeficiency, Bacille Calmette–Guérin (BCG) vaccination can lead to dissemination and severe infection, including severe intracranial infection, called disseminated BCG disease (BCGosis), which is ch...
Pneumocystis jirovecii is an opportunistic fungal pathogen responsible for Pneumocystis pneumonia (PCP), a severe infection that remains a major cause of morbidity and mortality among immunocompromised patients, particularly in non-HIV immunosuppress...
Mayaro virus (MAYV) is an arthritogenic alphavirus transmitted by mosquitoes and is the causative agent of Mayaro fever. This disease is associated with symptoms such as arthralgia and myalgia, which may persist for months or even years. Currently, n...
Orthohepanaviruses are viruses that infect a number of mammals, including humans and non-human primates. However, previous studies in great apes in Gabon in 2001 found one strain of hepadnavirus (HBV ChBassi strain) displaying genetic recombination b...
This study investigated the prevalence and molecular characteristics of canine vector-borne pathogens (CVBPs) circulating in diverse dog populations in Thailand by using molecular diagnostic methods. A total of 400 blood samples were collected from f...
Background: HPV16 is the most prevalent high-risk genotype associated with cervical cancer, yet the genetic variability and immune potential of the replication protein E1 are less characterized in asymptomatic infections. We assessed HPV16 E1 diversi...
Antimicrobial resistance (AMR) has emerged as one of the most significant global health challenges affecting both human and veterinary medicine. The growing prevalence of resistant bacterial strains in livestock and companion animals not only comprom...
Whiteflies, including Aleyrodes proletella, are major agricultural pests which cause significant yield losses through direct feeding damage and virus transmission. The entomopathogenic fungus Beauveria bassiana is a promising alternative to synthetic...
The clinical cases described in this text add to the limited literature on chronic and allergic rhinosinusitis caused by dematiaceous fungi, particularly Curvularia spicifera. These cases highlight the growing recognition of fungal infections as a si...
Mucormycosis, triggered by fungi of the order Mucorales, represents a potentially fatal invasive mycosis, with death rates over 50% despite intensive therapy. The COVID-19 pandemic brought a sharp increase in cases, especially in individuals with dia...
Human cytomegalovirus (HCMV) remains an important medical problem in multiple patient settings despite the availability of antivirals. In part, this is linked to resistance, cost and restrictions on use in several patient settings. More generally, it...
Objective: The aim of this study was to characterize the epidemiological features and whole-genome characteristics of H5 subtype avian influenza viruses circulating in Jining City during 2024–2025, and to provide scientific evidence for avian i...
Nematode-trapping fungi are saprophytic organisms that can transform their mycelium into a parasitic lifestyle, forming traps to capture and feed on nematodes. Although this transition is triggered by environmental conditions, the genetic regulation...
Zika virus (ZIKV) is an emerging flavivirus associated with congenital malformations and ocular complications, representing a significant public health concern. Retinal pigment epithelium (RPE) cells play a key role in maintaining retinal integrity a...
Asymptomatic pharyngeal Neisseria meningitidis (Nm) carriage is seen in >30% of sexually transmitted infection (STI) clinic attendees. With increasing reports of Nm urethritis and STI-related invasive disease outbreaks, longitudinal assessment and...
Canine leishmaniosis can cause a variety of signs. The detailed assessment of disease severity lacks a standardized, validated scoring system. This prospective study aimed to develop and validate an objective scoring system (“Total Leishmania S...
Human bocavirus (HBoV) is an important respiratory pathogen in young children, but recent data from Jordan are limited. This study assessed the positivity rate, epidemiological profile, clinical manifestations, and predictors of HBoV infection among...
Madagascar experienced a severe measles epidemic between September 2018 and mid-2019, resulting in more than 146,000 cases and 1200 deaths, primarily among children under 15 years of age. This epidemic occurred in a context of low vaccination coverag...
Actinobacillus pleuropneumoniae (APP) is the bacterial agent associated with porcine pleuropneumonia, a severe respiratory disease with significant economic impact due to increased mortality and elevated therapeutic costs, whose progression may be ex...
Yersinia enterocolitica strains of biotype 4 (BT4) are the most prevalent in human cases in France, followed by biotype 2 (BT2). We evaluated four BT4 porcine (P) isolates and four BT2 bovine (B) isolates for their ability to survive at 4 °C in c...
Southeast Asia (SEA) faces persistent gaps in regional understanding and control of ticks and tick-borne diseases (TBDs) despite recent advances (2023–2025). The second international symposium on ticks and TBDs in SEA (Singapore, August 2025),...
Following acute infection, herpes simplex virus type 1 (HSV-1) establishes life-long latency in neurons. Although sensory neurons in trigeminal ganglia (TG) are primary sites for latency, the brainstem is also an important site for latency. The ratio...
Weather conditions, especially temperature, rainfall, and humidity, affect the transmission and spread of West Nile virus (WNV). This study investigated the effects of weather patterns on WNV activity in Croatia using climatological, equine seropreva...
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