Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
6.8
3.3
Journals
Pathogens
Special Issues
Advances in Yersinia: Pathogenesis, Host Response, Epidemiology and Ecology...
Due to scheduled maintenance work on our servers, there may be short service disruptions on this website between 11:00 and 12:00 CEST on March 28th.
share announcement

Advances in Yersinia: Pathogenesis, Host Response, Epidemiology and Ecology of Diseases, Prevention, and Treatment

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Bacterial Pathogens".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 1097

Special Issue Editors

Prof. Dr. Deborah Anderson

E-Mail Website
Guest Editor
Department of Pathobiology and Integrative Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA
Interests: Yersinia; plague; innate immunity to bacterial infection; vector-borne disease
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Vladimir Motin

E-Mail Website
Guest Editor
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA
Interests: Yersinia; plague; bacterial pathogenesis; systemsbiology; host defense and immunity; diagnostics; therapeutics and vaccines

Special Issue Information

Dear Colleagues, 

The Yersinia genus encompasses four major pathogens, including Yersinia pestis, which causes the deadly bubonic plague. Pathogen evolution and successful zoonotic transmission cycles have led to the emergence and reemergence of human diseases with associated mortality. This Special Issue focuses on understanding the pathogenesis, transmission, and evolution of diseases caused by Yersinia pathogens. We feature recent progress highlighted at the 15th International Yersinia Symposium, which took place in Ulaanbaatar, Mongolia, in September 2025, bringing together the top scientists worldwide to share recent progress towards understanding the global persistence of Yersinia pathogens.

In addition to papers from the symposium, we welcome original research and review articles that address any of the Yersinia pathogenic species, including Y. pestis, Y. pseudotuberculosis, Y. enterocolitica, and Y. ruckeri. Articles that report on bacterial pathogenesis, disease ecology and epidemiology, transmission, and infection and immunity are responsive to this call.

Prof. Dr. Deborah Anderson
Prof. Dr. Vladimir Motin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Yersinia pathogenesis
  • host response
  • plague vaccines
  • Yersinia genomics
  • zoonotic transmission
  • emerging and reemerging yersiniosis
  • plague
  • vaccines
  • flea transmission

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

16 pages, 1910 KB  
Article
A Novel, Broad-Spectrum, Virulent Bacteriophage Targeting Yersinia pestis Isolated from the Soil of Wild Rodent Nests in Yunnan Province, China
by Ying Long, Youhong Zhong, Pan Liu, Chunpeng Mao, Haipeng Zhang, Liyuan Shi, Shaogui Zi, Xinyu Qin, Zongti Shao, Rongji Cao, Hongbaiyu Liu, Qingwen Gao, Ling Yang, Yuming Chen, Yuanying Shen and Peng Wang
Pathogens 2025, 14(12), 1195; https://doi.org/10.3390/pathogens14121195 - 24 Nov 2025
Viewed by 788
Abstract
As promising biological tools, bacteriophages offer broad potential applications in disease diagnosis, treatment, and food safety. This study is the first to isolate a novel bacteriophage, designated vB_YpP_JC53 (abbreviated JC53), from the soil of wild rodent nests in plague-endemic areas of Yunnan Province. [...] Read more.
As promising biological tools, bacteriophages offer broad potential applications in disease diagnosis, treatment, and food safety. This study is the first to isolate a novel bacteriophage, designated vB_YpP_JC53 (abbreviated JC53), from the soil of wild rodent nests in plague-endemic areas of Yunnan Province. This bacteriophage is a T7-like phage that has the broadest host range among all T7-like phages discovered to date and remains stable under varying temperature and pH conditions. Comparative genomic analysis through NCBI revealed that the nucleotide sequence of phage JC53 shares 94.98% homology (95% coverage) with phage PSTCR2, a member of the Solymavirus genus, while exhibiting substantially lower similarity to known Yersinia phages. Further phylogenetic and collinearity analyses demonstrate that JC53 represents an evolutionarily distinct lineage, clearly diverging from Yersinia-infecting, T7-like, and Shigella phages, suggesting the emergence of a novel evolutionary branch. Its low ANI values relative to Yersinia phages and mosaic genome organization indicate a complex evolutionary origin, reflecting the extensive diversity of environmental phage populations. Collectively, these findings support the designation of JC53 as a novel Yersinia phage. Genome sequencing revealed that JC53 has a genome size of 39,415 bp, with a total of 52 predicted open reading frames. The broad bacteriophage spectrum of JC53 challenges the long-standing perception that T4-like bacteriophages primarily depend on a wide host range. These findings suggest that, within plague foci, JC53 may maintain ecological fitness by targeting other bacteria rather than strictly relying on Yersinia pestis. As a result, JC53 holds potential as an ecological control agent with the potential to suppress plague transmission by regulating the microbial community structure within foci. Full article
(This article belongs to the Special Issue Advances in Yersinia: Pathogenesis, Host Response, Epidemiology and Ecology of Diseases, Prevention, and Treatment)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop