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Current Oncology, Volume 28, Issue 5

October 2021 - 80 articles

Cover Story: Prostate cancer is one of the most commonly diagnosed cancers and the second greatest cause of tumor-related death in men. Prostate-specific membrane antigen is overexpressed on the surface of prostate tumors and metastases, making it an ideal target for prostate cancer diagnosis and therapy. Radionuclide therapies targeting this antigen are currently an option for patients with metastatic castration-resistant prostate cancer. However, the membrane antigen is not prostate-specific and is also expressed by other organs, such as the kidneys and salivary glands. Therefore, these radionuclide therapies directed against these antigens could also affect the functions of such organs.View this paper
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Articles (80)

  • Review
  • Open Access
20 Citations
4,621 Views
10 Pages

13 October 2021

Lung cancer is the most fatal and frequently diagnosed malignant tumor. Neoadjuvant therapy is a promising approach for prolonging survival and increasing the chance of cure rates for patients with potentially resectable disease. Currently, many ther...

  • Review
  • Open Access
17 Citations
5,312 Views
18 Pages

Exercise to Reduce Anthracycline-Mediated Cardiovascular Complications in Breast Cancer Survivors

  • Sonu S. Varghese,
  • Will J. Johnston,
  • Cameron R. Eekhoudt,
  • Melanie R. Keats,
  • Davinder S. Jassal and
  • Scott A. Grandy

13 October 2021

While developments in cancer therapeutics have greatly reduced morbidity and mortality in females with breast cancer, it comes at a cost of an increased risk of cardiovascular complications. In particular, anthracyclines, like doxorubicin, which are...

  • Article
  • Open Access
5 Citations
2,952 Views
13 Pages

Synaptotagmin 13 Is Highly Expressed in Estrogen Receptor-Positive Breast Cancer

  • Takahiro Ichikawa,
  • Masahiro Shibata,
  • Takahiro Inaishi,
  • Ikumi Soeda,
  • Mitsuro Kanda,
  • Masamichi Hayashi,
  • Yuko Takano,
  • Dai Takeuchi,
  • Nobuyuki Tsunoda and
  • Yasuhiro Kodera
  • + 1 author

12 October 2021

Background: Accumulating evidence indicates tumor-promoting roles of synaptotagmin 13 (SYT13) in several cancers; however, no studies have investigated its expression in breast cancer (BC). This study aimed to clarify the significance of SYT13 in BC....

  • Review
  • Open Access
28 Citations
7,059 Views
16 Pages

12 October 2021

Small cell lung cancer (SCLC) remains a poorly understood disease with aggressive features, high relapse rates, and significant morbidity as well as mortality, yet persistently limited treatment options. For three decades, the treatment algorithm of...

  • Article
  • Open Access
10 Citations
2,828 Views
11 Pages

11 October 2021

Objective: Self-rated health (SRH) is a salient patient outcome for cancer survivors, and depressive mood and education are known determinants of cancer survivors’ SRH. Moving beyond the well-established direct association between depressive mood, ed...

  • Feature Paper
  • Review
  • Open Access
16 Citations
7,602 Views
14 Pages

Breast Cancer Surgery: New Issues

  • Francesca Magnoni,
  • Sofia Alessandrini,
  • Luca Alberti,
  • Andrea Polizzi,
  • Anna Rotili,
  • Paolo Veronesi and
  • Giovanni Corso

11 October 2021

Since ancient times, breast cancer treatment has crucially relied on surgeons and clinicians making great efforts to find increasingly conservative approaches to cure the tumor. In the Halstedian era (mid-late 19th century), the predominant practice...

  • Review
  • Open Access
15 Citations
4,117 Views
13 Pages

Recent Advances in Photodynamic Imaging and Therapy in Hepatobiliary Malignancies: Clinical and Experimental Aspects

  • Atsushi Nanashima,
  • Masahide Hiyoshi,
  • Naoya Imamura,
  • Koichi Yano,
  • Takeomi Hamada and
  • Kengo Kai

11 October 2021

The therapeutic and diagnostic modalities of light are well known, and derivative photodynamic reactions with photosensitizers (PSs), specific wavelengths of light exposure and the existence of tissue oxygen have been developed since the 20th century...

  • Article
  • Open Access
9 Citations
2,777 Views
11 Pages

The Influence of Adjuvant Chemotherapy Dose Intensity on Five-Year Outcomes in Resected Colon Cancer: A Single Centre Retrospective Analysis

  • Suganija Lakkunarajah,
  • Daniel A. Breadner,
  • Hanbo Zhang,
  • Ellen Yamanaka,
  • Andrew Warner and
  • Stephen Welch

9 October 2021

There is evidence that achieving a dose intensity > 80% in adjuvant colon cancer treatment improves survival. In total, 192 consecutive patients with resected stage III and high-risk stage II colon cancer that received adjuvant chemotherapy were r...

  • Review
  • Open Access
29 Citations
8,631 Views
17 Pages

Cognitive Assessment Tools Recommended in Geriatric Oncology Guidelines: A Rapid Review

  • Gina Tuch,
  • Wee Kheng Soo,
  • Ki-Yung Luo,
  • Kinglsey Frearson,
  • Ek Leone Oh,
  • Jane L. Phillips,
  • Meera Agar and
  • Heather Lane

8 October 2021

Cognitive assessment is a cornerstone of geriatric care. Cognitive impairment has the potential to significantly impact multiple phases of a person’s cancer care experience. Accurately identifying this vulnerability is a challenge for many cancer car...

  • Article
  • Open Access
17 Citations
3,383 Views
12 Pages

8 October 2021

Aims: The purpose of this study was to assess the effectiveness of a navigational radiofrequency ablation device with concurrent vertebral augmentation in the treatment of posterior vertebral body metastatic lesions, which are technically difficult t...

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Curr. Oncol. - ISSN 1718-7729