Special Issues

Current Oncology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Outcomes and New Treatments in Pediatric Brain Tumors
edited by Sébastien Perreault and Craig Erker
submission deadline 30 Apr 2026 | 7 articles | Viewed by 25804 | Submission Open
Keywords: pediatric neuro-oncology; central nervous system tumors; treatment approaches
(This special issue belongs to the Section Neuro-Oncology)
Quality of Life and Management of Pediatric Cancer submission deadline 30 Apr 2026 | 4 articles | Viewed by 11180 | Submission Open
Keywords: pediatric palliative care; oncology; quality of life; early management
(This special issue belongs to the Section Childhood, Adolescent and Young Adult Oncology)
Advances in Geriatric Oncology: Toward Optimized Cancer Care
edited by Michael J. Lind
submission deadline 30 Apr 2026 | 7 articles | Viewed by 9571 | Submission Open
Keywords: oncogeriatrics; clinical trials; prehabilitation; elderly cancer patients; cancer care
(This special issue belongs to the Section Palliative and Supportive Care)
Health Disparities and Outcomes in Cancer Survivors submission deadline 30 Apr 2026 | 3 articles | Viewed by 6132 | Submission Open
Keywords: cancer survivorship; quality of life; social behavioral determinants of health (SBDH); health disparities; symptom management
(This special issue belongs to the Section Psychosocial Oncology)
Health Economics in Oncology: Addressing Financial Toxicity, Value-Based Care, and Equity
edited by Marcell Csanádi
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1922 | Submission Open
Keywords: financial toxicity; cost-effectiveness; value-based care; cancer care; economic sustainability; health policy; treatment affordability; underserved populations; digital health; oncology economics
(This special issue belongs to the Section Health Economics)
AI-Powered Oncologic Nuclear Medicine in Clinical Translation: Advanced Assessment of Tumor Load and Microenvironment
edited by
submission deadline 30 Apr 2026 | 2 articles | Viewed by 1463 | Submission Open
Keywords: AI in nuclear medicine; PET- and SPECT-imaging; radiomics and deep learning; tumor microenvironment; tumor burden quantification; theranostics; precision oncology; immuno-oncology imaging; clinical translation; predictive modeling
Surgery in Locally Advanced Non-Small Cell Lung Cancer
edited by Marc Boada
submission deadline 30 Apr 2026 | 1 articles | Viewed by 1106 | Submission Open
Keywords: lung cancer; pancoast tumor; locally advanced tumor; thoracic surgery; oligometastatic disease; salvage surgery
(This special issue belongs to the Section Thoracic Oncology)
Microsurgical Management of Chronic Cancer-Related Lymphedema
edited by Elisabeth A. Kappos and
submission deadline 30 Apr 2026 | Viewed by 310 | Submission Open
Keywords: microsurgery; chronic cancer-related lymphedema; lymphatic reconstruction; surgical techniques; quality of life
(This special issue belongs to the Section Surgical Oncology)
Management of Orbital Tumors
edited by
submission deadline 30 Apr 2026 | Viewed by 294 | Submission Open
Keywords: orbital tumor; diagnostic; multidisciplinary approaches; personalized treatment; imaging techniques
Shaping the Future of Oncology: The Role of Generative AI in Clinical and Research Environments
edited by , Emily Rinderknecht and Maximilian Haas
submission deadline 31 May 2026 | 7 articles | Viewed by 13927 | Submission Open
Keywords: generative AI in oncology; AI-driven cancer diagnostics; personalized cancer treatment; AI in clinical decision making; oncology research innovation; AI-assisted therapeutic strategies; cancer care technology; patient-centered AI tools and apps; translational oncology and AI; future of oncology; artificial intelligence
Innovative Therapeutic Strategies, Biomarkers, and Molecular Pathways in Gastrointestinal and Hepatobiliary Cancers
edited by Anwaar Saeed and
submission deadline 31 May 2026 | 5 articles | Viewed by 12746 | Submission Open
Keywords: gastrointestinal cancers; hepatobiliary cancers; immunotherapy; targeted therapies; combination treatments; biomarkers; early diagnosis; prognosis; personalized medicine; molecular pathways; drug development targets
(This special issue belongs to the Section Gastrointestinal Oncology)
Feature Advancements in Section "Childhood, Adolescent and Young Adult Oncology"
edited by and Maria Otth
submission deadline 31 May 2026 | 2 articles | Viewed by 8423 | Submission Open
Keywords: childhood; adolescent and young adult cancer; survivorship; care models; transition; rehabilitation
(This special issue belongs to the Section Childhood, Adolescent and Young Adult Oncology)
Surgical and Medical Management of Pancreatic Tumors: Indication, Techniques, and Prognostic Factors
edited by , Antonella Delvecchio and Riccardo Memeo
submission deadline 31 May 2026 | 1 articles | Viewed by 984 | Submission Open
Keywords: pancreatic tumors; pancreatic surgery; neoadjuvant therapy; adjuvant therapy; short- and long-term outcomes; pancreatic diseases; surgical complication; recurrence rate; medical management; prognostic factors
(This special issue belongs to the Section Surgical Oncology)
Innovation in Gynecologic Cancer Surgery
edited by
submission deadline 31 May 2026 | 1 articles | Viewed by 930 | Submission Open
Keywords: hysterectomy; gynecologic cancers; surgical oncology; minimally invasive surgery; fertility preservation; survivorship; cost-effectiveness
(This special issue belongs to the Section Gynecologic Oncology)
Hypofractionated Radiotherapy for Prostate Cancer: Emerging Evidence and Clinical Practice
edited by
submission deadline 31 May 2026 | Viewed by 279 | Submission Open
Keywords: hypofractionated radiotherapy; prostate cancer; ultra-hypofractionation; image-guided radiotherapy (IGRT); toxicity and outcomes; patient selection; radiotherapy techniques; combined modality therapy
(This special issue belongs to the Section Genitourinary Oncology)
Gastrointestinal Tumors: Prevention, Screening and Predictive Analytics
edited by Mohamed I. Elsaid, and Vinod Rustgi
submission deadline 1 Jun 2026 | 2 articles | Viewed by 1268 | Submission Open
Keywords: gastrointestinal and hepatobiliary cancers; prevention and screening; chemoprevention; risk stratification; biomarkers and liquid biopsy (ctDNA); imaging and radiomics; predictive analytics and machine learning; causal inference; population-based studies; implementation science and health equity
(This special issue belongs to the Section Gastrointestinal Oncology)
Recent Advances in Surgical Strategies for Managing Metastatic Colorectal Cancer
edited by Fabrizio D'Acapito and Marco Vaira
submission deadline 15 Jun 2026 | 3 articles | Viewed by 6442 | Submission Open
Keywords: metastatic colorectal cancer; liver metastases; parenchymal-sparing hepatectomy; staged hepatectomy; minimally invasive liver resection; cytoreductive surgery; HIPEC; PIPAC; peritoneal surface metastases; biomarker-based stratification
(This special issue belongs to the Section Gastrointestinal Oncology)
The Impact of Tumor Microenvironment on Therapeutic Resistance
edited by
submission deadline 15 Jun 2026 | Viewed by 687 | Submission Open
Keywords: tumor microenvironment; therapeutic resistance; stromal– immune crosstalk
Advances in Novel Biomarkers for Kidney Cancer
edited by Brittney Hanerhoff Cotta
submission deadline 15 Jun 2026 | Viewed by 258 | Submission Open
Keywords: kidney cancer; renal cell carcinoma; biomarkers; genomics; risk stratification; prognosis
(This special issue belongs to the Section Genitourinary Oncology)
Surgery and Beyond: The Evolving Landscape of Glioma Management
edited by
submission deadline 15 Jun 2026 | Viewed by 227 | Submission Open
Keywords: neurosurgery; CNS tumor; surgery; therapeutic innovations; diagnostic innovations
(This special issue belongs to the Section Neuro-Oncology)
Targeted Molecular Therapeutics for Urologic Cancers: Advances, Emerging Strategies, and the Road Ahead
edited by
submission deadline 15 Jun 2026 | Viewed by 226 | Submission Open
Keywords: urologic neoplasm; circRNA; molecular targeted therapy; therapeutic resistance; precision medicine
(This special issue belongs to the Section Genitourinary Oncology)
Recent Advances in Immune Checkpoint Inhibition and Antibody Drug Conjugates in Urothelial Carcinoma
edited by Qian Janie Qin
submission deadline 30 Jun 2026 | 3 articles | Viewed by 5187 | Submission Open
Keywords: immune checkpoint inhibition; antibody drug conjugates; urothelial carcinoma; therapeutic combinations; biomarkers; resistance mechanisms; treatment efficacy; cancer immunotherapy
(This special issue belongs to the Section Genitourinary Oncology)
BCMA-Directed CAR-T Therapy in Relapsed or Refractory Multiple Myeloma
edited by Al-Ola A. Abdallah
submission deadline 30 Jun 2026 | 2 articles | Viewed by 4036 | Submission Open
Keywords: BCMA-directed CAR-T therapy; multiple myeloma; relapsed multiple myeloma; refractory multiple myeloma; B-cell maturation antigen; immunotherapy; treatment outcomes
(This special issue belongs to the Section Hematology)
Advances in PET/CT for Predicting Cancer Outcomes
edited by Ahmad Shariftabrizi
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1765 | Submission Open
Keywords: FDG PET/CT; PSMA PET/CT; dotatate PET/CT; tumor heterogeneity; radiomics; CAR T-cell therapy; rare tumors; radiogenomics; immunotherapy; targeted therapy; PET physics; radiotracer metabolism
Prevention, Early Detection and Management of Skin Cancer
edited by and
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1182 | Submission Open
Keywords: skin cancer; dermato-oncology; cutaneous oncology; melanoma; non-melanomatous skin cancers; basal cell carcinoma; squamous cell carcinoma; Merkel cell carcinoma; sebaceous carcinoma and other adnexal carcinomas; prevention and detection; treatment; biomarkers; immunotherapy and radiotherapy; precision medicine; UV radiation; surgery; targeted therapies
Recent Advancements in the Surgical Treatment of Brain Tumors—2nd Edition
edited by and Florian Gessler
submission deadline 30 Jun 2026 | 1 articles | Viewed by 869 | Submission Open
Keywords: brain tumors; intraoperative imaging; supramarginal resection; fluorescence-guided surgery; awake craniotomy; complication management; neurooncology; functional mapping; neuronavigation; intraoperative radiotherapy
(This special issue belongs to the Section Neuro-Oncology)
PD-1 and PD-L1 in Cancer Immunotherapy submission deadline 30 Jun 2026 | 1 articles | Viewed by 772 | Submission Open
Keywords: PD-1; PD-L1; cancer immunotherapy; immune checkpoint inhibitors; resistance mechanisms; combination therapies
Therapeutic Advances in Cystectomy for Bladder Cancer
edited by Saum B. Ghodoussipour
submission deadline 30 Jun 2026 | 1 articles | Viewed by 670 | Submission Open
Keywords: bladder cancer; cystectomy; therapeutic advances; surgical techniques; personalized treatment
(This special issue belongs to the Section Genitourinary Oncology)
Advancing Precision Medicine in Hepatocellular Carcinoma: The Comprehensive Role of Liquid Biopsy
edited by
submission deadline 30 Jun 2026 | Viewed by 377 | Submission Open
Keywords: circulating tumor cells; hepatocellular carcinoma; precision medicine; tumor heterogeneity; early diagnosis; prognosis; personalized treatment
(This special issue belongs to the Section Cell Therapy)
Recent Advances in Artificial Intelligence-Based Approaches for Breast Cancer
edited by
submission deadline 30 Jun 2026 | Viewed by 345 | Submission Open
Keywords: breast cancer; artificial intelligence; multimodal data; breast cancer datasets; AI model validation; benchmarking; literature appraisal; explainable AI for breast cancer; personalized medicine; generative AI for breast cancer
(This special issue belongs to the Section Breast Cancer)
Pain and Symptom Management in Cancer Patients
edited by Lynn R. Gauthier
submission deadline 30 Jun 2026 | Viewed by 322 | Submission Open
Keywords: cancer patients; pain management; symptom management; supportive care
Targeting KRAS in Lung Cancer: Current Status and Future Directions
edited by Sally Lau
submission deadline 30 Jun 2026 | Viewed by 263 | Submission Open
Keywords: KRAS mutations; non-small cell lung cancer; targeted therapy; KRAS G12C inhibitors; translational research; combination therapy; clinical outcomes
(This special issue belongs to the Section Thoracic Oncology)
From Innovation to Impact: Age-Adaptive Oncology for Just and Precision-Driven Care
edited by Tanyanika Phillips
submission deadline 30 Jun 2026 | Viewed by 251 | Submission Open
Keywords: age-adaptive; oncology; older adults; aging; cancer; precision medicine; biological aging; functional aging; accelerated aging; biomarkers; therapeutics
(This special issue belongs to the Section Palliative and Supportive Care)
Transforming Pancreatic Cancer Treatment: Innovations in Molecular Diagnostics and Treatment Advances
edited by Nicola Normanno, and
submission deadline 30 Jun 2026 | Viewed by 247 | Submission Open
Keywords: pancreatic cancer; liquid biopsy; organoids; therapy resistance; predictive biomarkers
(This special issue belongs to the Section Oncology Biomarkers)
Advances in Targeted Therapies and Pharmacogenomics of Leukemia
edited by Nicolas N Nassar
submission deadline 30 Jun 2026 | Viewed by 225 | Submission Open
Keywords: blood cancer; targeted therapy; immunotherapy; primary and secondary resistance; pharmacogenetics; combination therapy; tumor microenvironment
Brain Metastases: Biomarkers, Diagnosis, Treatment, Prognosis and Survival
edited by Katarzyna Jerzak
submission deadline 30 Jun 2026 | Viewed by 196 | Submission Open
Keywords: brain metastases; biomarkers; diagnosis and imaging; targeted and immunotherapy; prognosis and survival
(This special issue belongs to the Section Neuro-Oncology)
Deep Insights into Acute Myeloid Leukemia: Molecular Targets and Evolving Treatment Paradigms
edited by
submission deadline 30 Jun 2026 | Viewed by 194 | Submission Open
Keywords: acute myeloid leukemia (AML); molecular targets; targeted therapy; treatment resistance; precision medicine; immunotherapy; multi-omics; relapsed/refractory leukemia; therapeutic strategies
(This special issue belongs to the Section Hematology)
The Role of Targeted Therapy in Head and Neck Cancers
edited by
submission deadline 30 Jun 2026 | Viewed by 188 | Submission Open
Keywords: cancer; head and neck squamous cell carcinoma (HNSCC); targeted therapy; molecular drug targets; cancer biomarkers; personalized medicine; resistance mechanisms; combination therapies; translation oncology
(This special issue belongs to the Section Head and Neck Oncology)
2nd Edition: Allogeneic Stem Cell Transplantation: Does the Conditioning Regimen Intensity Still Matter?
edited by Imran Ahmad
submission deadline 30 Jun 2026 | Viewed by 179 | Submission Open
Keywords: conditioning; preparative; regimen; allogeneic; hematopoietic; transplantation; myeloablative; nonmyeloablative; reduced
(This special issue belongs to the Section Hematology)
Molecular Integrative Genomics in Cancer
edited by
submission deadline 15 Jul 2026 | 1 articles | Viewed by 2253 | Submission Open
Keywords: somatic mutation; cytogenetic abnormality; amplification; deletion; gene fusion; MSI; methylation; liquid biopsy; cell-free DNA; gene– environment interaction; targeted therapy; precision medicine
Combined Therapies for Hepatocellular Carcinoma submission deadline 20 Jul 2026 | 4 articles | Viewed by 12308 | Submission Open
Keywords: hepatocellular carcinoma; combined therapies; immunotherapy; locoregional therapy; external beam radiation
(This special issue belongs to the Section Gastrointestinal Oncology)
Unveiling the Economic Impact of Cancer Treatment
edited by
submission deadline 20 Jul 2026 | Viewed by 296 | Submission Open
Keywords: financial toxicity; cost-effectiveness; health equity; cancer economics; value-based care; economic disparities; survi-vorship; policy interventions; global burden; healthcare access
(This special issue belongs to the Section Health Economics)
Thoracic Malignancies and Immunity: Advances, Challenges, and Future Directions of Immunotherapy
edited by Giacomo Cusumano
submission deadline 30 Jul 2026 | 1 articles | Viewed by 1097 | Submission Open
Keywords: lung cancer (NSCLC and SCLC); malignant pleural  mesothelioma; immune checkpoint inhibitors; biomarkers (PD-L1; TMB; ctDNA); tumor microenvironment & immune evasion; combination therapies (chemo-IO; IO-IO; radiotherapy); neoadjuvant and adjuvant immunotherapy; immune-related adverse events (irAEs); resistance mechanisms & re-challenge; real-world evidence & translational research
(This special issue belongs to the Section Thoracic Oncology)
Routine Screening for Distress, Depression and Anxiety in Oncology: Where Are We Now?
edited by Daniel C. McFarland and Lee A. Kehoe
submission deadline 31 Jul 2026 | 2 articles | Viewed by 3484 | Submission Open
Keywords: psychological distress; depression; anxiety; oncology; routine screening; cancer care; patient outcomes
(This special issue belongs to the Section Psychosocial Oncology)
Recent Advances in Breast Reconstruction Following Cancer
edited by
submission deadline 31 Jul 2026 | 1 articles | Viewed by 618 | Submission Open
Keywords: prepectoral implant-based reconstruction; post-reconstruction radiation; mastectomy pattern; non-abdominal autologous-based breast reconstruction; breast reconstruction complication; patient-reported outcome; breast sensation; fat grafting; enhanced recovery after surgery (ERAS) protocols; oncoplastic breast reconstruction; lymphatic reconstruction
(This special issue belongs to the Section Breast Cancer)
Innovations in the Clinical Research of Chronic Myeloid Leukemia: From Targeted Therapies to Allogeneic Stem Cell Transplantation
edited by Jeffrey H. Lipton
submission deadline 31 Jul 2026 | Viewed by 331 | Submission Open
Keywords: chronic myeloid leukemia; tyrosine kinase inhibitors; treatment resistance; allogeneic stem cell transplantation; stem cell persistence; treatment-free remission; targeted therapies
(This special issue belongs to the Section Hematology)
Advances in Interventional Radiology for Oncological Management
edited by Alex L. Wallace and
submission deadline 31 Jul 2026 | Viewed by 282 | Submission Open
Keywords: interventional oncology; tumor ablation; embolization; image-guided therapy; personalized medicine; translational research; cancer care
Contrast-Enhanced Imaging for Breast Cancer Detection and Management
edited by Enida Bufi, , Matteo Sammarra and Angela Bucaro
submission deadline 31 Jul 2026 | Viewed by 251 | Submission Open
Keywords: contrast-enhanced mammography (CEM); breast cancer imaging; dense breast tissue; dual-energy mammography; radiomics; artificial intelligence; iodinated contrast medium
(This special issue belongs to the Section Breast Cancer)
Hope Amidst Challenges: Therapies for Relapsed/Refractory Multiple Myeloma
edited by
submission deadline 10 Aug 2026 | Viewed by 175 | Submission Open
Keywords: RRMM; quadruplet therapy; CART-cell; bispecific antibodies; antibody drug conjugates (ADC); minimal residual disease (MRD)
(This special issue belongs to the Section Hematology)
Surgical Advances in the Management of Gastrointestinal Cancers
edited by Boris Luis Gala-López
submission deadline 15 Aug 2026 | 3 articles | Viewed by 2894 | Submission Open
Keywords: gastrointestinal cancers; surgical innovation; multimodal therapy; precision oncology; minimally invasive surgery
(This special issue belongs to the Section Gastrointestinal Oncology)
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