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Current Oncology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New and Emerging Trends in Prostate Cancer

edited by

Tamim Niazi

and Steven Tisseverasinghe

submission deadline 31 Dec 2025 | 8 articles | Viewed by 15288 | Submission Open

Keywords: prostate SBRT; recurrent prostate cancer; treatment intensification with ARPIs; PARP inhibitors; lutetium-177; immunotherapy; oligometastases

(This special issue belongs to the Section Genitourinary Oncology)

Optimizing Surgical Management for Gynecologic Cancers

edited by Jacob D. McGee

submission deadline 31 Dec 2025 | 4 articles | Viewed by 7192 | Submission Open

Keywords: pre-operative optimization; de-escalation; surgical approach; risk stratification; quality of Life; novel techniques

(This special issue belongs to the Section Gynecologic Oncology)

2nd Edition—Haematological Neoplasms: Diagnosis and Management

edited by

Stefano Ascani

Magda Zanelli

and

Francesca Sanguedolce

submission deadline 31 Dec 2025 | 2 articles | Viewed by 6733 | Submission Open

Keywords: myeloid neoplasms; lymphoid neoplasms; pathology; molecular biology; precision medicine; biomarkers

(This special issue belongs to the Section Hematology)

Clinical Advances in Thyroid Cancer: Biomarker-Driven Diagnosis, Oncogenesis Insights, and Translational Therapies

edited by Salma Khan

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1444 | Submission Open

Keywords: thyroid cancer; oncogenesis; translational therapies; fine-needle aspiration (FNA); precision medicine; targeted therapy

(This special issue belongs to the Section Head and Neck Oncology)

Psychological Interventions for Cancer Survivors

edited by Christian Schulz-Quach

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1239 | Submission Open

Keywords: cancer survivors; psychological interventions; mental health; quality of life; existential– phenomenological approaches; relational frameworks; resilience; evidence-based therapies; post-treatment care

(This special issue belongs to the Section Psychosocial Oncology)

Combining Radiotherapy and Immunotherapy for Cancer Treatment

edited by Yufei Liu

submission deadline 31 Dec 2025 | Viewed by 545 | Submission Open

Keywords: radiation oncology; immunotherapy; immunomodulation; immune checkpoint inhibitors; abscopal effect; stereotactic body ra-diation therapy; antibody– drug conjugate; CAR-T cell therapy; tumor-infiltrating lymphocytes

2nd Edition—Chronic Lymphocytic Leukemia: Therapy and Outcome

edited by

Andrea Visentin

submission deadline 31 Dec 2025 | Viewed by 277 | Submission Open

Keywords: chronic lymphocytic leukemia; microenvironment; BTK inhibitors; BCL2 inhibitors; PI3K inhibitors; infection; prognostic factors; predictive factors; richter syndrome

(This special issue belongs to the Section Hematology)

REAL Canadian Breast Cancer Alliance Collection

edited by Katarzyna J. Jerzak, Nathalie LeVasseur,

Nathaniel Bouganim

and

Mita Manna

submission deadline 31 Dec 2025 | Viewed by 260 | Submission Open

Keywords: HER2-positive; hormone receptor-positive; triple-negative; metastatic breast cancer; early-stage breast cancer; Canadian consensus recommendations; evidence-based; REAL Alliance

(This special issue belongs to the Section Breast Cancer)

Surgical Advances in the Management of Gastrointestinal Cancers

edited by Boris Luis Gala-López

submission deadline 15 Jan 2026 | 1 articles | Viewed by 956 | Submission Open

Keywords: gastrointestinal cancers; surgical innovation; multimodal therapy; precision oncology; minimally invasive surgery

(This special issue belongs to the Section Gastrointestinal Oncology)

Estrogen-Receptor Low Positive (ER-Low) Breast Cancer: A New (or Old?) World to Discover

edited by Eleonora Lai and

Gavino Faa

submission deadline 15 Jan 2026 | Viewed by 492 | Submission Open

Keywords: breast cancer; estrogen receptor low positive; treatment implications; endocrine treatment; immunotherapy; chemotherapy; translational research; clinical research

(This special issue belongs to the Section Breast Cancer)

Self-Management/Patient Activation and Self-Management Support Interventions for Cancer Survivors

edited by

Doris Howell

submission deadline 31 Jan 2026 | 3 articles | Viewed by 8587 | Submission Open

Keywords: self-management interventions; supported self-management; health coaching; patient activation; healthy lifestyle behaviors; patient activation; cancer and cancer survivorship

(This special issue belongs to the Section Oncology Nursing)

Routine Screening for Distress, Depression and Anxiety in Oncology: Where Are We Now?

edited by Daniel C. McFarland and Lee A. Kehoe

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2412 | Submission Open

Keywords: psychological distress; depression; anxiety; oncology; routine screening; cancer care; patient outcomes

(This special issue belongs to the Section Psychosocial Oncology)

Patient-Reported Outcomes Including Health-Related Quality of Life in Cancer Clinical Trials

edited by Caroline Hamm

submission deadline 31 Jan 2026 | 1 articles | Viewed by 590 | Submission Open

Keywords: patient-reported outcomes; guidelines; health-related quality of life; clinical trials; ethical considerations; prognosis

(This special issue belongs to the Section Palliative and Supportive Care)

Advances in Multiparametric MRI and Artificial Intelligence for Bladder Cancer: From Diagnosis to Personalized Treatment Strategies

edited by

Thierry Boellaard

submission deadline 31 Jan 2026 | Viewed by 309 | Submission Open

Keywords: multiparametric MRI; artificial intelligence; bladder cancer; diagnosis; personalized treatment strategies; prognosis

(This special issue belongs to the Section Genitourinary Oncology)

Basal Cell Carcinoma: Diagnosis, Treatment and Prognosis

edited by Andrzej Bieniek

submission deadline 31 Jan 2026 | Viewed by 240 | Submission Open

Keywords: basal cell carcinoma; skin cancer; diagnostic techniques; surgical and non-surgical treatment modalities; targeted therapies; long-term management and prevention

(This special issue belongs to the Section Dermato-Oncology)

Cancer Rehabilitation: Innovations in Practice & Enhancing Survivorship Care

edited by

David M. Langelier

and Sara Parke

submission deadline 15 Feb 2026 | 4 articles | Viewed by 3929 | Submission Open

Keywords: cancer rehabilitation; physiatry; survivorship; symptom management; impairment; disability

(This special issue belongs to the Section Palliative and Supportive Care)

Adaptive Radiotherapy: Advanced Imaging for Personalised Treatment

edited by

Sweet Ping Ng

and Michael G. Jameson

submission deadline 15 Feb 2026 | Viewed by 296 | Submission Open

Keywords: adaptive radiotherapy; advanced imaging; personalized radiotherapy

Clinical Outcomes and New Treatments in Pediatric Brain Tumors

edited by Sébastien Perreault and Craig Erker

submission deadline 28 Feb 2026 | 7 articles | Viewed by 20808 | Submission Open

Keywords: pediatric neuro-oncology; central nervous system tumors; treatment approaches

(This special issue belongs to the Section Neuro-Oncology)

Bridging Borders: A Global Perspective on Colorectal Cancer Research and Prevention

edited by

Laith Alrubaiy

submission deadline 28 Feb 2026 | 1 articles | Viewed by 4344 | Submission Open

Keywords: colorectal cancer (CRC); global health; mass screening; early detection of cancer; artificial intelligence (AI); epidemiology; health disparities; diagnostic technologies; public health; therapeutics

(This special issue belongs to the Section Gastrointestinal Oncology)

Immunotherapy for Head and Neck Cancer: Biomarkers, Trials, and Transformative Outcomes

edited by

Jong Chul Park

submission deadline 28 Feb 2026 | Viewed by 199 | Submission Open

Keywords: immunotherapy; head and neck cancer; biomarkers; combination therapy; clinical outcomes

(This special issue belongs to the Section Head and Neck Oncology)

Innovations in the Clinical Research of Chronic Myeloid Leukemia: From Targeted Therapies to Allogeneic Stem Cell Transplantation

edited by Jeffrey H. Lipton

submission deadline 28 Feb 2026 | Viewed by 162 | Submission Open

Keywords: chronic myeloid leukemia; tyrosine kinase inhibitors; treatment resistance; allogeneic stem cell transplantation; stem cell persistence; treatment-free remission; targeted therapies

(This special issue belongs to the Section Hematology)

Future Perspectives for Treatment and Diagnosis of Acute Myeloid Leukemia (AML)

edited by

Mitchell Sabloff

and Brian Leber

submission deadline 1 Mar 2026 | 2 articles | Viewed by 6216 | Submission Open

Keywords: pathophysiology; biomarker; diagnosis/prognosis/predictive/monitoring (indication/limitations); treatment advances; intensive; less intensive; refractory leukemia; cellular therapies

(This special issue belongs to the Section Hematology)

Biliary Tract Cancer Updates: Advancements and Insights

edited by Kristen R. Spencer

submission deadline 15 Mar 2026 | 9 articles | Viewed by 25320 | Submission Open

Keywords: biliary tract cancer; intrahepatic cholangiocarcinoma; extrahepatic cholangiocarcinoma; gallbladder cancer; targeted therapy; immunotherapy; molecular profiling; clinical trials

(This special issue belongs to the Section Gastrointestinal Oncology)

An In-Depth Review of Desmoid Tumours

edited by

Lloyd Mack

submission deadline 15 Mar 2026 | 4 articles | Viewed by 10504 | Submission Open

Keywords: desmoid tumour; desmoid-like fibromatosis; active surveillance; molecular pathogenesis; surgery and margins; radiation therapy; chemotherapy; novel treatment options; functional outcomes; quality of life

(This special issue belongs to the Section Bone and Soft Tissue Oncology)

Cost Effectiveness vs. Affordability in the Age of Targeted Drug Therapies

edited by Ramy Saleh

submission deadline 15 Mar 2026 | 4 articles | Viewed by 10318 | Submission Open

Keywords: cost-effectiveness; affordability; drugs; financial; cancers; treatment; targeted drug therapies

(This special issue belongs to the Section Health Economics)

Palliative Care in Oncology: Current Advances

edited by Olav F. Dajani,

Arne Westgaard

and Martin Kummen

submission deadline 15 Mar 2026 | 1 articles | Viewed by 799 | Submission Open

Keywords: palliative care; oncology; cancers; pain; support; well-being

(This special issue belongs to the Section Palliative and Supportive Care)

Clinical Advances and Therapeutic Challenges in Small-Cell Lung Cancer and Rare Thoracic Cancers

edited by

Tommaso Martino De Pas

submission deadline 20 Mar 2026 | 3 articles | Viewed by 5895 | Submission Open

Keywords: pleural mesothelioma; thymic cancer; neuroendocrine thoracic tumors; small-cell lung cancer; rare tumors; thoracic cancer

(This special issue belongs to the Section Thoracic Oncology)

Clinical Management of Cervical Cancer

edited by Vanessa Samouëlian

submission deadline 31 Mar 2026 | 4 articles | Viewed by 7646 | Submission Open

Keywords: cervical cancer; surgical treatments; de-escalation; systemic treatments; immunotherapy; biomarkers; personalized treatment

(This special issue belongs to the Section Gynecologic Oncology)

Neurofibromatosis Type 1 (NF1) Tumor Spectrum

edited by Jay Pundavela, Kyle B. Williams and R. Taylor Sundby

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2720 | Submission Open

Keywords: neurofibromatosis type 1 (NF1); malignant tumors; tumor spectrum; molecular and cellular mechanisms; malignant peripheral nerve sheath tumors (MPNSTs); targeted therapies; immunotherapies; prognostic factors; survival outcomes

(This special issue belongs to the Section Neuro-Oncology)

Surgical Management of Patients with Hepatobiliary and Pancreatic Malignancies

edited by Cameron E Gaskill and Jessica E. Maxwell

submission deadline 31 Mar 2026 | 2 articles | Viewed by 2033 | Submission Open

Keywords: surgical management; hepatobiliary malignancies; pancreatic malignancies; surgical techniques; postoperative outcomes; survival rates; regional disparities; minimally invasive surgery; long-term survival; adjuvant therapies

(This special issue belongs to the Section Surgical Oncology)

Quality of Life and Management of Pediatric Cancer

edited by

Luca Giacomelli

and

Momcilo Jankovic

submission deadline 30 Apr 2026 | 4 articles | Viewed by 8382 | Submission Open

Keywords: pediatric palliative care; oncology; quality of life; early management

(This special issue belongs to the Section Childhood, Adolescent and Young Adult Oncology)

Advances in Geriatric Oncology: Toward Optimized Cancer Care

edited by Michael J. Lind

submission deadline 30 Apr 2026 | 5 articles | Viewed by 6547 | Submission Open

Keywords: oncogeriatrics; clinical trials; prehabilitation; elderly cancer patients; cancer care

(This special issue belongs to the Section Palliative and Supportive Care)

Health Disparities and Outcomes in Cancer Survivors

edited by

Claire Jungyoun Han

submission deadline 30 Apr 2026 | 3 articles | Viewed by 4802 | Submission Open

Keywords: cancer survivorship; quality of life; social behavioral determinants of health (SBDH); health disparities; symptom management

(This special issue belongs to the Section Psychosocial Oncology)

Health Economics in Oncology: Addressing Financial Toxicity, Value-Based Care, and Equity

edited by Marcell Csanádi

submission deadline 30 Apr 2026 | 1 articles | Viewed by 775 | Submission Open

Keywords: financial toxicity; cost-effectiveness; value-based care; cancer care; economic sustainability; health policy; treatment affordability; underserved populations; digital health; oncology economics

(This special issue belongs to the Section Health Economics)

AI-Powered Oncologic Nuclear Medicine in Clinical Translation: Advanced Assessment of Tumor Load and Microenvironment

edited by

Christian Furth

submission deadline 30 Apr 2026 | 1 articles | Viewed by 456 | Submission Open

Keywords: AI in nuclear medicine; PET- and SPECT-imaging; radiomics and deep learning; tumor microenvironment; tumor burden quantification; theranostics; precision oncology; immuno-oncology imaging; clinical translation; predictive modeling

Microsurgical Management of Chronic Cancer-Related Lymphedema

edited by Elisabeth A. Kappos and

Adriano Fabi

submission deadline 30 Apr 2026 | Viewed by 175 | Submission Open

Keywords: microsurgery; chronic cancer-related lymphedema; lymphatic reconstruction; surgical techniques; quality of life

(This special issue belongs to the Section Surgical Oncology)

Surgery in Locally Advanced Non-Small Cell Lung Cancer

edited by Marc Boada

submission deadline 30 Apr 2026 | 1 articles | Viewed by 149 | Submission Open

Keywords: lung cancer; pancoast tumor; locally advanced tumor; thoracic surgery; oligometastatic disease; salvage surgery

(This special issue belongs to the Section Thoracic Oncology)

Management of Orbital Tumors

edited by

Peerooz Saeed

submission deadline 30 Apr 2026 | Viewed by 128 | Submission Open

Keywords: orbital tumor; diagnostic; multidisciplinary approaches; personalized treatment; imaging techniques

Shaping the Future of Oncology: The Role of Generative AI in Clinical and Research Environments

edited by

Matthias May

, Emily Rinderknecht and Maximilian Haas

submission deadline 31 May 2026 | 6 articles | Viewed by 10195 | Submission Open

Keywords: generative AI in oncology; AI-driven cancer diagnostics; personalized cancer treatment; AI in clinical decision making; oncology research innovation; AI-assisted therapeutic strategies; cancer care technology; patient-centered AI tools and apps; translational oncology and AI; future of oncology; artificial intelligence

Innovative Therapeutic Strategies, Biomarkers, and Molecular Pathways in Gastrointestinal and Hepatobiliary Cancers

edited by Anwaar Saeed and

Azhar Saeed

submission deadline 31 May 2026 | 4 articles | Viewed by 8559 | Submission Open

Keywords: gastrointestinal cancers; hepatobiliary cancers; immunotherapy; targeted therapies; combination treatments; biomarkers; early diagnosis; prognosis; personalized medicine; molecular pathways; drug development targets

(This special issue belongs to the Section Gastrointestinal Oncology)

Feature Advancements in Section "Childhood, Adolescent and Young Adult Oncology"

edited by

Katrin Scheinemann

and Maria Otth

submission deadline 31 May 2026 | 2 articles | Viewed by 7151 | Submission Open

Keywords: childhood; adolescent and young adult cancer; survivorship; care models; transition; rehabilitation

(This special issue belongs to the Section Childhood, Adolescent and Young Adult Oncology)

Surgical and Medical Management of Pancreatic Tumors: Indication, Techniques, and Prognostic Factors

edited by

Michele Tedeschi

, Antonella Delvecchio and Riccardo Memeo

submission deadline 31 May 2026 | 1 articles | Viewed by 484 | Submission Open

Keywords: pancreatic tumors; pancreatic surgery; neoadjuvant therapy; adjuvant therapy; short- and long-term outcomes; pancreatic diseases; surgical complication; recurrence rate; medical management; prognostic factors

(This special issue belongs to the Section Surgical Oncology)

Innovation in Gynecologic Cancer Surgery

edited by

Sarfraz Ahmad

submission deadline 31 May 2026 | Viewed by 252 | Submission Open

Keywords: hysterectomy; gynecologic cancers; surgical oncology; minimally invasive surgery; fertility preservation; survivorship; cost-effectiveness

(This special issue belongs to the Section Gynecologic Oncology)

Hypofractionated Radiotherapy for Prostate Cancer: Emerging Evidence and Clinical Practice

edited by

Hiromichi Ishiyama

submission deadline 31 May 2026 | Viewed by 140 | Submission Open

Keywords: hypofractionated radiotherapy; prostate cancer; ultra-hypofractionation; image-guided radiotherapy (IGRT); toxicity and outcomes; patient selection; radiotherapy techniques; combined modality therapy

(This special issue belongs to the Section Genitourinary Oncology)

Gastrointestinal Tumors: Prevention, Screening and Predictive Analytics

edited by Mohamed I. Elsaid,

Electra D. Paskett

and Vinod Rustgi

submission deadline 1 Jun 2026 | Viewed by 38 | Submission Open

Keywords: gastrointestinal and hepatobiliary cancers; prevention and screening; chemoprevention; risk stratification; biomarkers and liquid biopsy (ctDNA); imaging and radiomics; predictive analytics and machine learning; causal inference; population-based studies; implementation science and health equity

(This special issue belongs to the Section Gastrointestinal Oncology)

Recent Advances in Surgical Strategies for Managing Metastatic Colorectal Cancer

edited by Fabrizio D'Acapito and Marco Vaira

submission deadline 15 Jun 2026 | 2 articles | Viewed by 4855 | Submission Open

Keywords: metastatic colorectal cancer; liver metastases; parenchymal-sparing hepatectomy; staged hepatectomy; minimally invasive liver resection; cytoreductive surgery; HIPEC; PIPAC; peritoneal surface metastases; biomarker-based stratification

(This special issue belongs to the Section Gastrointestinal Oncology)

The Impact of Tumor Microenvironment on Therapeutic Resistance

edited by

Ziqing Chen

submission deadline 15 Jun 2026 | Viewed by 483 | Submission Open

Keywords: tumor microenvironment; therapeutic resistance; stromal– immune crosstalk

Surgery and Beyond: The Evolving Landscape of Glioma Management

edited by