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Molecules, Volume 28, Issue 21

November-1 2023 - 220 articles

Cover Story: Nowadays, diabetes is still a serious problem in our civilization. This is evidenced by the increasing incidence rate, which applies to all types of the disease (type I, type II, and gestational diabetes). Preventing its development and impact on human life involves frequent measurements, which are necessary to maintain proper glucose levels. Herein, we proposed nature-inspired biomolecular corona based on poly(caffeic acid) as a low-potential and time-stable glucose biosensor to detect glucose in real solutions, including human blood and serum. View this paper
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Articles (220)

  • Article
  • Open Access
27 Citations
3,578 Views
22 Pages

New Thiazolyl-Pyrazoline Derivatives as Potential Dual EGFR/HER2 Inhibitors: Design, Synthesis, Anticancer Activity Evaluation and In Silico Study

  • Mariam M. Fakhry,
  • Amr A. Mattar,
  • Marwa Alsulaimany,
  • Ebtesam M. Al-Olayan,
  • Sara T. Al-Rashood and
  • Hatem A. Abdel-Aziz

6 November 2023

A new series of thiazolyl-pyrazoline derivatives (4a–d, 5a–d 6a, b, 7a–d, 8a, b, and 10a, b) have been designed and synthesized through the combination of thiazole and pyrazoline moieties, starting from the key building blocks pyraz...

  • Article
  • Open Access
3 Citations
2,682 Views
17 Pages

6 November 2023

Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous interstellar molecules. However, the formation mechanisms of PAHs and even the simplest cyclic aromatic hydrocarbon, benzene, are not yet fully understood. Recently, we reported the statistical a...

  • Article
  • Open Access
6 Citations
3,148 Views
14 Pages

Antimicrobial Activity of Manganese(I) Tricarbonyl Complexes Bearing 1,2,3-Triazole Ligands

  • Sofia Friães,
  • Cândida Trigueiros,
  • Clara S. B. Gomes,
  • Alexandra R. Fernandes,
  • Oscar A. Lenis-Rojas,
  • Marta Martins and
  • Beatriz Royo

6 November 2023

Background. Antimicrobial resistance is one of the most pressing health issues of our time. The increase in the number of antibiotic-resistant bacteria allied to the lack of new antibiotics has contributed to the current crisis. It has been predicted...

  • Article
  • Open Access
4 Citations
1,803 Views
15 Pages

6 November 2023

In this study, a new 3D porous PVDF-foam-imprinted membrane (PPIM) for the selective separation of artemisinin (ART) was first prepared via the dopamine adhesion of pre-synthesized MIPs into the interior of the PPIM. In the PPIM, the pre-synthesized...

  • Article
  • Open Access
7 Citations
2,846 Views
19 Pages

6 November 2023

Astragalus membranaceus is a traditional Chinese medicine derived from the roots of Astragalus membranaceus (Fisch.) Bge., which has the same medicinal and edible uses in China. It is also widely used in daily food, and its pharmacological effects ma...

  • Article
  • Open Access
3 Citations
2,537 Views
12 Pages

6 November 2023

The N-functionalized indole is a privileged structural framework in a wide range of bioactive molecules. The nucleophilic addition between indoles with vinylene carbonate proceeded smoothly in the presence of K2CO3 as the catalyst to produce novel in...

  • Article
  • Open Access
3 Citations
3,250 Views
23 Pages

Effects of Radiation-Induced Skin Injury on Hyaluronan Degradation and Its Underlying Mechanisms

  • Jiahui Dong,
  • Boyuan Ren,
  • Yunfei Tian,
  • Guanqun Peng,
  • Huiting Zhai,
  • Zhiyun Meng,
  • Ruolan Gu,
  • Hui Gan,
  • Zhuona Wu and
  • Yunbo Sun
  • + 2 authors

6 November 2023

Radiation-induced skin injury (RISI) is a frequent and severe complication with a complex pathogenesis that often occurs during radiation therapy, nuclear incidents, and nuclear war, for which there is no effective treatment. Hyaluronan (HA) plays an...

  • Article
  • Open Access
8 Citations
2,440 Views
16 Pages

Structural Analysis and Antioxidant and Immunoregulatory Activities of an Exopolysaccharide Isolated from Bifidobacterium longum subsp. longum XZ01

  • Xingyuan Zhang,
  • Jing Gong,
  • Wenyi Huang,
  • Wen Liu,
  • Chong Ma,
  • Rongyao Liang,
  • Ye Chen,
  • Zhiyong Xie,
  • Pei Li and
  • Qiongfeng Liao

6 November 2023

Bifidobacterium longum subsp. longum XZ01 (BLSL1) is a new strain (isolated from the intestines of healthy people and deposited with the preservation number GDMCC 61618). An exopolysaccharide, S-EPS-1, was successfully isolated from the strain and th...

  • Article
  • Open Access
12 Citations
3,129 Views
15 Pages

Study on the Dynamic Changes in Non-Volatile Metabolites of Rizhao Green Tea Based on Metabolomics

  • Ao Sun,
  • Guolong Liu,
  • Luyan Sun,
  • Chun Li,
  • Qiu Wu,
  • Jianhua Gao,
  • Yuanzhi Xia and
  • Yue Geng

6 November 2023

The processing of tea leaves plays a crucial role in the formation of the taste of the resulting tea. In order to study the compositions of and changes in taste-related substances during the processing of Rizhao green tea, non-targeted metabolomics w...

  • Article
  • Open Access
1 Citations
2,405 Views
12 Pages

6 November 2023

Lung cancer has a high incidence rate worldwide, necessitating the development of new drugs. Although Magnolia figo (Lour.) DC. is known for its medicinal properties, studies on its efficacy against lung cancer are lacking. This study investigated wh...

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Molecules - ISSN 1420-3049