Steroid Compounds with Potential Biological Activity
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Chemical Biology".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 31016
Special Issue Editors
Interests: Organic synthesis; androstane derivatives; biologically active compounds
Interests: steroid synthesis; core modification; secosteroids; homosteroids; molecular mechanics; molecular dynamics; drug design
Special Issues, Collections and Topics in MDPI journals
Interests: medicinal chemistry; organic chemistry; organic synthesis; steroids
Interests: study of the biological activity of modified steroids and other compounds in vitro on cell cultures and animal tissues and in vivo on animal models: testing of antiestrogenic, anticancer, antioxidant activity, measuring the effect on steroid-converting enzymes
Special Issue Information
Dear Colleagues,
We warmly invite you to contribute to this Special Issue of Molecules entitled “Steroid Compounds with Potential Biological Activity”.
Steroids are a large group of compounds whose structure is based on a 17-carbon skeleton, with a specific cyclopentanoperhydrophenanthrene ring system. Natural steroids have been fine-tuned through evolution to build membranes, to act as chemical messengers that regulate metabolic, immune, and reproductive functions in animals, as well as to stimulate growth or protect animal organisms. The steroid core represents a suitable motive for structural modifications. Therefore, a large group of semi-synthetic steroid derivatives have occupied the attention of synthetic chemists as well as medicinal chemists due to their potential biological activity, including anticancer, antibacterial, anti-inflammatory, (anti)hormonal and other activities.
This Special Issue is dedicated to both experimental and theoretical studies on steroid chemistry, structural biology, biosynthesis, metabolism, and pharmacology. The Issue focuses on the isolation and synthesis of steroid compounds, diverse in origin, as well as their structural characterization and identification. Manuscripts relating to in vitro, in vivo or in silico studies of pharmacological properties, molecular biology, biochemistry, and structural biology of steroids are encouraged.
We look forward to the submission of original research papers or reviews to this Special Issue of Molecules entitled “Steroid Compounds with Potential Biological Activity”.
Dr. Marina Savić
Dr. Erzsébet Mernyák
Dr. Jovana Ajdukovic
Prof. Dr. Suzana Jovanović-Šanta
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- natural steroid compounds
- semi-synthetic steroid compounds
- isolation
- structure elucidation
- bioactive steroids
- physiological activity
- metabolism
- medicinal chemistry of steroids
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