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Molecules, Volume 17, Issue 5

May 2012 - 107 articles

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Articles (107)

  • Article
  • Open Access
105 Citations
10,365 Views
14 Pages

24 May 2012

An activity-directed fractionation and purification process was used to isolate antitumor compounds from the roots of Belamcanda chinensis (L.) DC. The ethyl acetate extract showed greater antitumor activities than the other extracts, consequently le...

  • Communication
  • Open Access
54 Citations
7,907 Views
9 Pages

24 May 2012

[3+2] Cycloaddition of azomethine imines with electron-deficient terminal alkynes was smoothly catalyzed by a chiral bis(imidazolidine)pyridine-CuOAc complex to give bicyclic pyrazolo[1,2-a]pyrazolone derivatives with up to 74% ee.

  • Article
  • Open Access
47 Citations
10,273 Views
10 Pages

Ipomoea aquatica Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity

  • Salim Said Alkiyumi,
  • Mahmood Ameen Abdullah,
  • Ahmed Salim Alrashdi,
  • Suzy Munir Salama,
  • Siddig Ibrahim Abdelwahab and
  • A. Hamid A. Hadi

22 May 2012

In the Indian system of traditional medicine (Ayurveda) it is recommended to consume Ipomoea aquatica to mitigate disorders like jaundice. In this study, the protective effects of ethanol extract of I. aquatica against liver damage were evaluated in...

  • Article
  • Open Access
113 Citations
13,801 Views
13 Pages

21 May 2012

This study was conducted to investigate the chemical and nutritional composition of Artemisia annua leaves in addition to determination of antioxidant potential of their extracts prepared in different solvents. Chemical composition was determined by...

  • Article
  • Open Access
42 Citations
7,106 Views
13 Pages

21 May 2012

The present study examines the effect of methanolic extract of T. violacea rhizomes on high cholesterol (2%) diet fed rats (HCD). At the end of 4 weeks, serum total protein, albumin, reduced glutathione (GSH), and markers of oxidative stress viz., ca...

  • Article
  • Open Access
12 Citations
5,552 Views
10 Pages

Effect of Soluble Sulfide on the Activity of Luminescent Bacteria

  • Ying Shao,
  • Ling-Ling Wu,
  • Hong-Wen Gao and
  • Feng Wang

21 May 2012

Sulfide is an important water pollutant widely found in industrial waste water that has attracted much attention. S2−, as a weak acidic anion, is easy hydrolyzed to HS− and H2S in aqueous solution. In this study, biological tests were performed to es...

  • Article
  • Open Access
37 Citations
6,290 Views
15 Pages

Physicochemical Characterization and Cytotoxic Activity Evaluation of Hydroxymethylferrocene:β-Cyclodextrin Inclusion Complex

  • Rosa Iacovino,
  • Jolanda Valentina Caso,
  • Filomena Rapuano,
  • Agostino Russo,
  • Marina Isidori,
  • Margherita Lavorgna,
  • Gaetano Malgieri and
  • Carla Isernia

21 May 2012

An inclusion complex of hydroxymethylferrocene (FeMeOH) with β-cyclodextrin (β-CD) was prepared in the solid state by different techniques such as physical mixture, coprecipitation, kneading and freeze-drying. The formation of the inclusion complex w...

  • Article
  • Open Access
49 Citations
7,727 Views
12 Pages

Antioxidant, Antimicrobial and Tyrosinase Inhibitory Activities of Xanthones Isolated from Artocarpus obtusus F.M. Jarrett

  • Najihah Mohd. Hashim,
  • Mawardi Rahmani,
  • Gwendoline Cheng Lian Ee,
  • Mohd Aspollah Sukari,
  • Maizatulakmal Yahayu,
  • Muhamad Aizat Mohd Amin,
  • Abd Manaf Ali and
  • Rusea Go

21 May 2012

One of the most promising plants in biological screening test results of thirteen Artocarpus species was Artocarpus obtusus FM Jarrett and detailed phytochemical investigation of powdered dried bark of the plant has led to the isolation and identific...

  • Review
  • Open Access
72 Citations
9,397 Views
17 Pages

Synthesis and Bioactivity of Secondary Metabolites from Marine Sponges Containing Dibrominated Indolic Systems

  • Adriano Mollica,
  • Marcello Locatelli,
  • Azzurra Stefanucci and
  • Francesco Pinnen

21 May 2012

Marine sponges. (e.g., Hyrtios sp., Dragmacidin sp., Aglophenia pleuma, Aplidium cyaneum, Aplidium meridianum.) produce bioactive secondary metabolites involved in their defence mechanisms. Recently it was demonstrated that several of those compounds...

  • Article
  • Open Access
42 Citations
7,058 Views
14 Pages

Synthesis and Evaluation of New β-Carboline-3-(4-benzylidene)-4H-oxazol-5-one Derivatives as Antitumor Agents

  • Franciele Cristina Savariz,
  • Mary Ann Foglio,
  • João Ernesto De Carvalho,
  • Ana Lúcia T. G. Ruiz,
  • Marta C. T. Duarte,
  • Mauricio Ferreira Da Rosa,
  • Emerson Meyer and
  • Maria Helena Sarragiotto

21 May 2012

In the present work, we report the synthesis and in vitro anticancer and antimicrobial activity evaluation of a new series of 1-substituted-β-carboline derivatives bearing a 4-benzylidene-4H-oxazol-5-one unity at C-3. The compound 2-[1-(4-methoxyphen...

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Molecules - ISSN 1420-3049