Molecules, Volume 31, Issue 2

Li₃PO₄ is a promising raw material for the low-cost synthesis of high-performance LiFePO₄. Reactive crystallization from low-concentration lithium-rich brine is a key process for the efficient preparation of high-quality Li₃PO₄ products. The effect o...

Herein, we disclose a highly efficient pathway toward 3-selenylated chromone derivatives via electrosynthesis domino C(sp²)-H bond selenylation/cyclization/deamination of 2-hydroxyaryl enaminones with diselenides. This method showed mild conditions,...

Shape-stabilized phase change materials (SSPCMs) have been a promising thermal energy storage (TES) solution to combine the high energy density of solid-to-liquid (SL) PCMs and the structural stability of solid–solid PCMs. Although polymeric ma...

The global food industry is undergoing a major shift driven by increasing consumer demand for clean-label and naturally preserved foods. Fresh pasta is highly vulnerable to fungal damage because of its high water activity (a_w > 0.85), typically ra...

The valorization of agri-food residues is crucial for advancing circular bioeconomy strategies and mitigating environmental impacts. Turnip greens (Brassica rapa subsp. sylvestris) are a traditional vegetable cultivated in southern Italy. While the e...

Carboxymethyl hydroxypropyl cellulose (CMHPC) combines the advantages of both carboxymethyl and hydroxypropyl substitutions, exhibiting superior solubility, viscosity characteristics, and enhanced salt tolerance compared to carboxymethyl cellulose (C...

The journal retracts the article titled, “TTF1, in the Form of Nanoparticles, Inhibits Angiogenesis, Cell Migration and Cell Invasion In Vitro and In Vivo in Human Hepatoma through STAT3 Regulation” [...]

A computational study of the mechanism of asymmetric hydrogenation of γ-keto acids with the Ni(S,S)-QuinoxP* system was conducted. The main steps of the reaction mechanism were determined, including the formation of the NiH(S,S-QuinoxP*)⁺ compl...

The widespread occurrence of pharmaceutical residues in aquatic environments necessitates the development of advanced porous materials for efficient remediation. This study investigates the adsorption mechanisms of ibuprofen and atenolol within the h...

Pea albumin is a high-quality plant-based protein with growing relevance in food applications, yet the effects of pH and thermal treatment on its structural and functional properties remain insufficiently understood. This study investigated the effec...

Background: Cardiac ischemia (CI) remains a leading cause of death worldwide, prompting an ongoing search for new treatment options. This study explored and compared the preventive cardioprotective effects of polyphenols extracted from red (RGP) and...

Conventional perming relies on oxidative agents that significantly damage hair. The thiol–Michael click perming strategy derived from linear aliphatic diols and diamines has been developed to avoid oxidative damage, but lacks repeatable perming...

A comprehensive two-dimensional liquid chromatography platform (LC × LC) was developed and validated for dermal permeability studies. In this implementation, the two separation dimensions were applied to mimic the layered structure of human ski...

Lignin, the most abundant renewable source of aromatic compounds, plays a pivotal role in advancing sustainable biorefineries and reducing dependence on fossil resources. Recent progress in integrated lignin valorization pathways has unlocked opportu...

Lanthanide coordination polymers have been developed at a fast rate during the past two decades due to their appealing applications in the modern field of materials science and emerging technologies like luminescence, magnetism, sensing, gas adsorpti...

Promising approach for the expansion of the functional food sector is combining various ingredients with potential health benefits. The aim of this study was to create protein aggregates by freeze-drying encapsulation. Rice or pea proteins were used...

4-hydroxy-TEMPO is a water-soluble nitroxide radical with potent antioxidant and redox-modulating properties. Its small molecular weight and membrane permeability enable it to act as a superoxide dismutase mimetic, efficiently scavenging reactive oxy...

Effectively separating and utilizing macerals based on their properties is crucial for the efficient and high-value utilization of coal. This study enhances the traditional screening method by employing primary and stepwise crushing techniques to sep...

The idea of collecting novel contributions relating to the chemistry of natural compounds in this Special Issue stemmed from the success of the first edition of the collection entitled “Natural Products Chemistry: Advances in Synthetic, Analyti...

Although various phosphorescent organic light-emitting diodes (PhOLEDs) have been developed, their lifetimes remain shorter than those of fluorescent OLEDs. In this study, a novel Pt(II) complex featuring a tetradentate ligand composed of bipyridine...

(1) Background: Diabetes mellitus is a chronic metabolic disease with a rising global prevalence. Mulberry leaf (ML), a traditional medicinal and edible plant, possesses notable hypoglycemic effects and has a long history of usage. This review aims t...

This article investigates the thermodynamic driving force of the interaction between lysozyme (Lys) and sulfated β-cyclodextrin (β-CDS), with a particular emphasis on the elusive role of hydration during polyelectrolyte–protein bindin...

This study investigated the dose-dependent impact of pear juice supplementation on the chemical composition, phenolic profile, and biological activity of kombucha during 14 days of fermentation. Four formulations (0–75% pear juice) were evaluat...

Fragmentation Resilience Energy Mass Spectrometry (FREMS) builds on the field of energy-resolved mass spectrometry and previously used methods, e.g., Survival Yield. It exploits breakdown energies at near “continuous” ramp (0.2% NCE incre...

The separation of rare earth elements (REEs) with similar chemical properties remains a relevant challenge today, most often addressed using liquid–liquid and solid-phase extraction with various chelating agents. Excellent complexing agents for...

Infertility represents a significant global health issue, and the use of antioxidants in sperm preservation techniques provides an effective strategy to improve sperm quality. This study aims to examine the phytochemical components of Phlai and Njui...

The still-growing demand for nutritious gluten-free products necessitates the development of a composite flour that addresses the nutritional deficiencies common in conventional gluten-free formulations. This study aimed to comprehensively characteri...

The gut microbiome produces thousands of metabolites with potential to modulate central nervous system function through peripheral or direct neural mechanisms. Tourette syndrome, attention-deficit/hyperactivity disorder, and autism spectrum disorder...

This review provides a comprehensive overview of recent progress in chitin-based nanomaterials and their composite engineering. Particular focus is placed on techniques for constructing self-assembled chitin nanofibers (ChNFs) with tightly bundled fi...

In response to growing interest in green additives derived from natural raw materials or post-production waste of natural origin, epoxy compositions containing the additive in the form of waste wood flour and microcellulose were prepared. The researc...

Chalcones have garnered significant research interest due to their various medical bioactivities. Several chalcone compounds have been approved for marketing and clinical use in the treatment of various diseases. A critical aspect of the action of ch...

Background: The golden apple snail (Pomacea canaliculata), an invasive species originating from South America, has inflicted considerable agricultural and ecological harm in non-native habitats. While the molluscicide niclosamide is currently effecti...

Olive and Chinese olive are rich sources of bioactive compounds with reported sensory and hepatoprotective activities; however, the synergistic effect between their functional components have not been systematically evaluated. In this study, DF3 (fun...

Plant-based fermented foods are increasingly promoted for glycemic control, yet their mechanisms and clinical impact remain incompletely defined. This narrative review synthesizes mechanistic, preclinical, and human data for key matrices—kimchi...

Suzetrigine was approved by the US American Food and Drug Administration in 2025 as the first oral, non-opioid, selective inhibitor of Na_V1.8 sodium channel for the treatment of acute pain. Therefore, it represents a groundbreaking advancement in pai...

The present study involves the isolation, structural elucidation, and biological evaluation of eight compounds from Pouzolzia zeylanica. From the n-hexane and ethyl acetate extracts of the plant, eight compounds were successfully isolated and identif...

Modern agriculture faces the critical need to develop sustainable, safe, and effective strategies for enhancing productivity, protecting plants and animals, and ensuring food security. Challenges posed by antibiotic resistance and the adverse environ...

Naturally inspired electrophilic scaffolds, such as chalcone, curcumin, aurone, C-5-monocarbonyl-curcumin, and bis-(arylidene)piperidone, are considered privileged structures because of their ability to interact with a variety of biological macromole...

This study presents a straightforward strategy for producing novel, effective and inexpensive functional non-noble metal-supported carbon materials made from abundant natural biomass. These materials offer a cost-effective alternative to noble metals...

In this study, we have investigated heterostructural TiO₂/BiVO₄ anodes to determine the effect of the amount and form of BiVO₄ nanoparticles on TiO₂ on the response of photoanodes under UV and visible illumination. BiVO₄ nanopowders were prepared and...

Germination is widely recognized as an effective strategy to enhance the nutritional quality and reduce anti-nutritional factors in plant foods. This study evaluated the impact of germination on Cruciferous vegetables (family Cruciferae or Brassicace...

Cholesterol plays a fundamental role in the human body—it stabilizes cell membranes, modulates gene expression, and is a precursor to steroid hormones, vitamin D, and bile salts. Its correct level is crucial for homeostasis, while both excess a...

Trypsin is one of the most extensively studied enzymes in biochemistry. However, little information is available on the role of the disulfide bonds to establish the correct conformation and enzyme activity during molecular evolution. To obtain this i...

Lithium-ion batteries (LIBs) face the safety hazard of thermal runaway (TR). Gas-sensing-based monitoring is one of the viable warning approaches for batteries during operation, and TR warning using semiconductor gas sensors has garnered widespread a...

In the search for solutions to the global health threat posed by antimicrobial resistance, the development of new compounds is crucial. In this context, the in vitro testing of known indolizinoquinolinedione analogs 1–7 revealed that N,N-syn re...

Among the metal-derived complexes, recently, tin derivatives have been investigated as promising anti-cancer drug candidates. Our previous study showed that the tin-based compound Bu₃SnOCOCF₃ (TBT) exerts cytotoxic activity on solid tumor cell lines....

Artificial metalloenzymes incorporating cobalt protoporphyrin IX (Co-PPIX) are promising for sustainable hydrogen production; however, slow protein preparation and a lack of suitable detection methods limit the systematic optimization of their cataly...

Dietary bioactive compounds derived from plant-based and fermented foods act as plei-otropic modulators of human health, exerting antioxidant, anti-inflammatory, cardiopro-tective, neuroprotective, and metabolic effects beyond basic nutrition. Whole...

Proteins are generally characterized by three-dimensional structures that are well suited for their specific function. It is much less accepted that a particular flexibility or plasticity of a protein is essential for performing its function. The lat...

Melanoma is an aggressive skin cancer that continues to present major therapeutic difficulties. Although targeted drugs and immune checkpoint inhibitors have improved outcomes, resistance and treatment-related toxicity limit long-term benefit. In rec...