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47 Results Found

  • Article
  • Open Access
5,207 Views
11 Pages

Characteristics and Treatment Strategies for Basicervical and Transcervical Shear Fractures of the Femoral Neck

  • Hiroaki Kijima,
  • Shin Yamada,
  • Tetsuya Kawano,
  • Motoharu Komatsu,
  • Yosuke Iwamoto,
  • Natsuo Konishi,
  • Hitoshi Kubota,
  • Hiroshi Tazawa,
  • Takayuki Tani and
  • Norio Suzuki
  • + 7 authors

10 November 2023

This study aimed to define basicervical and transcervical shear fractures using area classification and to determine the optimal osteosynthesis implants for them. The clinical outcomes of 1042 proximal femur fractures were investigated. A model of th...

  • Case Report
  • Open Access
1,748 Views
8 Pages

First Case Report of Uterine Leiomyosarcoma Diagnosed After Transcervical Fibroid Ablation

  • Dimitrios Chronas,
  • Inna Jörg,
  • Kristina Bolten,
  • Laura Reich,
  • David Toub and
  • Zsuzsanna Varga

27 December 2024

Background: Uterine fibroids are benign monoclonal neoplasms of the myometrium, representing the most common female pelvic neoplasms globally. Treatments may be invasive, such as hysterectomy and myomectomy, non-invasive, such as medical therapy or f...

  • Article
  • Open Access
8 Citations
4,122 Views
10 Pages

Transcervical Fibroid Ablation (TFA): Update on Pregnancy Outcomes

  • Leslie Hansen-Lindner,
  • Juliette Schmid-Lossberg and
  • David Toub

14 May 2024

Background/Objectives: Transcervical fibroid ablation (TFA) is an incisionless method to treat symptomatic uterine fibroids. While safety regarding future pregnancy remains to be established, TFA does not preclude the possibility of pregnancy, and a...

  • Communication
  • Open Access
8 Citations
4,253 Views
8 Pages

9 January 2020

Transcervical artificial insemination (AI) after the surgical incision of cervical folds (SICF) could represent a valid alternative to laparoscopic AI when frozen thawed semen is used. The aim of this experiment was to compare pregnancy (PR) and lamb...

  • Study Protocol
  • Open Access
4 Citations
2,239 Views
14 Pages

Comparison of Transoral and Transcervical Ultrasonography with MRI for the Diagnostic Work-Up of Oropharynx Tumors: A Protocol for a Multicenter Clinical Trial (SPOTUS)

  • Martin Garset-Zamani,
  • Gitte Bjørn Hvilsom,
  • Thomas Kjærgaard,
  • Christina Caroline Plaschke,
  • Christoffer Holst Hahn,
  • Mikkel Kaltoft,
  • Padraig O’Leary,
  • Natalie Lassen Frid,
  • Rikke Norling and
  • Danijela Dejanovic
  • + 7 authors

This study protocol for a prospective, multicenter, diagnostic, clinical trial describes the integration of transoral and transcervical ultrasonography (US) in the initial clinical work-up of patients referred to tertiary head and neck cancer centers...

  • Article
  • Open Access
11 Citations
4,653 Views
6 Pages

Feasibility of Transcervical Robotic-Assisted Esophagectomy (TC-RAMIE) in a Cadaver Study—A Future Outlook for an Extrapleural Approach

  • Peter Philipp Grimminger,
  • Pieter Christiaan van der Sluis,
  • Hubert Stein,
  • Hauke Lang,
  • Richard van Hillegersberg and
  • Jan-Hendrik Egberts

1 September 2019

In recent years, the evolution of advanced robotic medical systems has increased rapidly. These technical developments have led to advanced robotic systems, such as the da Vinci Xi, which allows superior controlled complex procedures and innovative s...

  • Article
  • Open Access
663 Views
16 Pages

Transcervical, Transabdominal and Transvaginal Chorionic Villus Sampling for Prenatal Diagnosis in Zagreb, Croatia: A Prospective Single-Operator Study on 5500 Cases

  • Petra Podobnik,
  • Tomislav Meštrović,
  • Mario Podobnik,
  • Ivan Bertović-Žunec,
  • Igor Lončar,
  • Kristian Kurdija,
  • Dženis Jelčić,
  • Zlata Srebreniković and
  • Slava Podobnik-Šarkanji

30 October 2025

Background/Objectives: Chorionic villus sampling (CVS) is a pivotal diagnostic tool for early prenatal detection of chromosomal and genetic abnormalities; however, the safety and diagnostic efficacy of different CVS approaches remain a subject of cli...

  • Article
  • Open Access
3 Citations
4,716 Views
12 Pages

The Design of a New Catheter for Transcervical Artificial Insemination in Ewes

  • Laura Falchi,
  • Maria Teresa Zedda,
  • Salvatore Pau,
  • Mauro Ledda,
  • Valentino Melosu and
  • Salvatore Pier Giacomo Rassu

23 November 2021

In ovine species, transcervical artificial insemination (TCAI) is limited by the poor quality of frozen–thawed semen and by the convoluted cervical lumen hampering the passage of inseminating devices. The aim of the study was to test the effici...

  • Article
  • Open Access
5 Citations
804 Views
9 Pages

Transcervical Extended Mediastinal Lymphadenectomy (TEMLA) for Staging of Non-Small-Cell Lung Cancer (NSCLC)

  • Marcin Zieliński,
  • Łukasz Hauer,
  • Jolanta Hauer,
  • Juliusz Pankowski,
  • Artur Szlubowski and
  • Tomasz Nabiałek

21 April 2011

Introduction: The aim of the study is to analyze diagnostic yield of the new surgical technique — the Transcervical Extended Mediastinal Lymphadenectomy (TEMLA) in preoperative staging of Non-Small-Cell Lung Cancer (NSCLC). Material and methods: Oper...

  • Article
  • Open Access
936 Views
11 Pages

Is It Possible to Access the Uterus of Sheep by Endoscopy: Studies of Vaginoscopy and Hysteroscopy with Transcervical Uterine Access in Sheep

  • Augusto Ryonosuke Taira,
  • Thiago da Silva Cardoso,
  • Renata Levy Amanajas,
  • Renata Sitta Gomes Mariano Landers,
  • Priscila Del Águila da Silva,
  • Victor Jóse Correia Santos,
  • Naiara Nantes Rodrigues,
  • Dayane Priscila Vrisman,
  • Felipe Faria Pereira da Câmara Barros and
  • Francisco Décio de Oliveira Monteiro
  • + 4 authors

23 May 2025

Given the endoscopic possibilities and the need to improve AI in sheep, the aim of this study was to develop a transcervical endoscopic technique for accessing the uterus in sheep. The study was conducted on 35 ewes divided according to the uterus ac...

  • Article
  • Open Access
1,004 Views
12 Pages

Exploring the Benefits of 3D Smart MRI in Resident Training and Surgical Planning for Transcervical Radiofrequency Ablation

  • Sepehr Janghorbani,
  • Victoria Weprinsky,
  • Alexandre Caprio,
  • Tamatha Fenster and
  • Bobak Mosadegh

Background: Transcervical radiofrequency ablation (TRFA), particularly using the SONATA® System, is a minimally invasive and uterus-preserving treatment for uterine fibroids. While effective, its reliance on intrauterine ultrasound (IUS) with lim...

  • Article
  • Open Access
1,513 Views
20 Pages

Background/Objectives: We generated a novel recombinant Vibrio cholerae ghost (rVCG)-based subunit vaccine incorporating the A1 subunit of cholera toxin (CTA1) and a multiepitope Chlamydia trachomatis (CT) antigen (MECA) derived from five chlamydial...

  • Review
  • Open Access
3 Citations
3,437 Views
16 Pages

Less Is More: Evaluating the Benefits of Minimally Invasive Spinal Surgery

  • Ali A. Mohamed,
  • Rakan Alshaibi,
  • Steven Faragalla,
  • Garrett Flynn,
  • Asad Khan,
  • Emma Sargent,
  • Youssef Mohamed,
  • Camberly Moriconi,
  • Cooper Williams and
  • Zev Karve
  • + 3 authors

25 December 2024

This review aims to explore the evolution, techniques, and outcomes of minimally invasive spine surgery (MISS) within the field of neurosurgery. We sought to address the increasing burden of spine degeneration in a rapidly aging population and the ne...

  • Case Report
  • Open Access
7 Citations
813 Views
3 Pages

A Case of a Very Elongated Styloid Process 8 cm in Length with Frequent Throat Pain for 10 Years

  • Takeshi Kusunoki,
  • Hirotomo Homma,
  • Yoshinobu Kidokoro,
  • Aya Yanai,
  • Mitsuhisa Fujimaki and
  • Katsuhisa Ikeda

25 March 2016

We experienced a case of an elongated styloid process that was 8 cm in length. The patient was a 68-year-old Japanese man with frequent episodes of left-sided throat pain for 10 years. The elongated styloid process could be diagnosed by 3D-computed t...

  • Review
  • Open Access
1 Citations
3,807 Views
18 Pages

A Novel Paradigm for Non-Invasive Prenatal Genetic Screening: Trophoblast Retrieval and Isolation from the Cervix (TRIC)

  • Kirim Hong,
  • Hee Jin Park,
  • Hee Yeon Jang,
  • Sung Han Shim,
  • Yoon Jang,
  • Soo Hyun Kim and
  • Dong Hyun Cha

As the prevalence of pregnancies with advanced maternal age increases, the risk of fetal chromosomal abnormalities is on the rise. Therefore, prenatal genetic screening and diagnosis have become essential elements in contemporary obstetrical care. Tr...

  • Article
  • Open Access
8 Citations
2,399 Views
12 Pages

Transoral Ultrasound in the Outpatient Clinic for the Diagnostic Work-Up of Oropharyngeal Cancer: A Feasibility Study

  • Martin Garset-Zamani,
  • Rikke Norling,
  • Christoffer Holst Hahn,
  • Tina Klitmøller Agander,
  • Christian von Buchwald and
  • Tobias Todsen

4 November 2023

Magnetic resonance imaging (MRI) is the preferred imaging modality for oropharyngeal cancers (OPCs), but it has difficulties distinguishing between small OPCs and unilateral tonsil hypertrophy. We hypothesized that surgeon-performed transoral ultraso...

  • Article
  • Open Access
1 Citations
749 Views
8 Pages

Transbronchial Needle Aspiration as a Diagnostic Method in Lung Cancer and Non-Malignant Mediastinal Adenopathy

  • Artur Szlubowski,
  • Jarosław Kużdżał,
  • Jerzy Soja,
  • Ewa Łączyńska,
  • Jolanta Hauer,
  • Piotr Kopiński,
  • Romana Tomaszewska and
  • Marcin Zieliński

13 April 2007

Introduction: The aim of the study was to assess the diagnostic yield of transbronchial needle aspiration (TBNA) in mediastinal or hilar adenopathy in: lung cancer, staging of NSCLC, sarcoidosis and other non-malignant diseases. Material and methods:...

  • Article
  • Open Access
1 Citations
710 Views
8 Pages

Ultrasound Guided Transbronchial Needle Aspiration as a Diagnostic Tool for Lung Cancer and Sarcoidosis

  • Artur Szlubowski,
  • Jarosław Kużdżał,
  • Juliusz Pankowski,
  • Anna Obrochta,
  • Jerzy Soja,
  • Jolanta Hauer,
  • Marcin Kołodziej and
  • Marcin Zieliński

22 June 2008

Introduction: The aim of the study was to assess the diagnostic yield of ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in mediastinal or hilar adenopathy in: (1) staging of non-small cell lung cancer (NSCLC) (97); (2) other malignant...

  • Article
  • Open Access
733 Views
5 Pages

Endoscopic Ultrasound-Guided Needle Aspiration in Lung Cancer

  • Artur Szlubowski,
  • Marcin Zieliński,
  • Joanna Figura,
  • Jolanta Hauer,
  • Witold Sośnicki,
  • Juliusz Pankowski,
  • Anna Obrochta and
  • Magdalena Jakubiak

26 June 2009

Introduction: The aim of the study was to assess the diagnostic yield of transoesophageal endoscopic ultrasound-guided needle aspiration (EUS-NA) in lung cancer (LC). Material and methods: Real time EUS-NA was performed under local anaesthesia and se...

  • Systematic Review
  • Open Access
27 Citations
8,036 Views
18 Pages

Reproductive and Obstetric Outcomes after UAE, HIFU, and TFA of Uterine Fibroids: Systematic Review and Meta-Analysis

  • Ayazhan Akhatova,
  • Gulzhanat Aimagambetova,
  • Gauri Bapayeva,
  • Antonio Simone Laganà,
  • Vito Chiantera,
  • Peter Oppelt,
  • Antonio Sarria-Santamera and
  • Milan Terzic

Novel treatment options for uterine fibroids, such as uterine artery embolization (UAE), ultrasound-guided and magnetic resonance-guided high-intensity focused ultrasound (USgHIFU and MRgHIFU), and transcervical radiofrequency ablation (TFA) methods,...

  • Article
  • Open Access
2 Citations
928 Views
15 Pages

Comparison of the Diagnostic Efficiency of Mediastinal Lymph Node Endobronchial and Endoesophageal Ultrasound with Transcervical Extended Mediastinal Lymphadenectomy in Operable Non-Small Cell Lung Cancer

  • Michal Wilkojc,
  • Pawel Gwozdz,
  • Sylweriusz Kosinski,
  • Juliusz Pankowski,
  • Artur Szlubowski,
  • Aleksandra Kiszka-Wilkojc,
  • Wojciech Czajkowski,
  • Robert Kwiatkowski and
  • Marcin Zielinski

1 July 2025

Objectives: The aim of the study was to compare the diagnostic efficiency between combined endobronchial ultrasound (EBUS)/endoesophageal ultrasound (EUS) and transcervical extended mediastinal lymphadenectomy (TEMLA) for preoperative staging of medi...

  • Review
  • Open Access
2 Citations
3,113 Views
13 Pages

Not All SAVR Are Created Equal: All the Approaches Available for Surgical Aortic Valve Replacement

  • Francesco Cabrucci,
  • Serge Sicouri,
  • Massimo Baudo,
  • Dimitrios E. Magouliotis,
  • Yoshiyuki Yamashita,
  • Beatrice Bacchi,
  • Dario Petrone,
  • Beman Wasef,
  • Aleksander Dokollari and
  • Massimo Bonacchi
  • + 1 author

Surgical Aortic Valve Replacement (SAVR) is still one of the pillars of cardiac surgery practice, and its role is evolving into a more complex operation. The competition with structural valve therapies and the urgent demand for less invasive solution...

  • Review
  • Open Access
23 Citations
7,550 Views
14 Pages

5 September 2014

The ability to capture and analyze fetal cells from maternal circulation or other sources during pregnancy has been a goal of prenatal diagnostics for over thirty years. The vision of replacing invasive prenatal diagnostic procedures with the prospec...

  • Article
  • Open Access
7 Citations
168 Views
6 Pages

Different Surgical Approaches for Multiple Fractured Atrophic Mandibles

  • Felipe Ladeira Pereira,
  • Walter Cristiano Gealh,
  • Carlos Eduardo Braga Barbosa and
  • Liogi Iwaki Filho

Atrophic edentulous mandible fractures in geriatric patients have low incidence but present several biological and biomechanical peculiarities that produce a nonunion rate of around 20%. Surgical extraoral approaches for internal fixation of these fr...

  • Case Report
  • Open Access
1,762 Views
17 Pages

Three-Leaf-Clover Thyroid and Minimally Invasive Trans-Cervical Synchronous Thyroidectomy and Ectopic Mediastinal Thyroid Tissue Removal: Does the Age of the Patient Count amid a Multifaceted Strategy?

  • Claudiu Nistor,
  • Mihai-Lucian Ciobica,
  • Oana-Claudia Sima,
  • Anca-Pati Cucu,
  • Mihai Costachescu,
  • Adrian Ciuche,
  • Lucian-George Eftimie,
  • Dana Terzea and
  • Mara Carsote

22 October 2024

Background: Ectopic organ-associated conditions belong to the larger panel of developmental ailments, and among this challenging medical and surgical chapter, ectopic endocrine glands-related picture is mostly focused on the presence of the ectopic p...

  • Review
  • Open Access
1 Citations
1,738 Views
11 Pages

Non-Surgical Approaches to the Management of the Intrathoracic Goiter—A Systematic Review

  • Cesare Miani,
  • Luca Giovanni Locatello,
  • Nicole Caiazza,
  • Anna Maria Bergamin-Bracale,
  • Stefania Rigo,
  • Maria Gabriella Rugiu,
  • Andrea Zuin and
  • Ricard Simo

29 October 2024

Background: Intrathoracic goiters (ITGs) are usually managed by surgical excision, However, over recent years, non-surgical strategies are emerging as an alternatives for treating this condition. Methods: A systematic review of research published sin...

  • Review
  • Open Access
6 Citations
6,263 Views
12 Pages

Transoral Approach to Parotid Tumors: A Review of the Literature

  • Giuseppe Riva,
  • Andrea Lorenzi,
  • Andrea Borello,
  • Andrea Albera,
  • Andrea Canale and
  • Giancarlo Pecorari

1 December 2022

Different surgical techniques have been proposed for parapharyngeal space tumors, including transcervical, transparotid, trans-mandibular, infratemporal, and transoral. The choice of the correct approach depends on the size, localization and nature o...

  • Interesting Images
  • Open Access
1 Citations
2,658 Views
9 Pages

Thyroglossal Duct Lipoma: A Case Report and a Systematic Review of the Literature for Its Management

  • Luca Giovanni Locatello,
  • Marilena Graziadio,
  • Elena D’Orlando,
  • Alfredo Vallone,
  • Cesare Miani,
  • Enrico Pegolo and
  • Maria Gabriella Rugiu

Thyroglossal duct (TGD) remnants in the form of cysts or fistulas usually present as midline neck masses and they are removed along with the central body of the hyoid bone (Sistrunk’s procedure). For other pathologies associated with the TGD tr...

  • Case Report
  • Open Access
2 Citations
3,260 Views
8 Pages

23 October 2022

Fetal maceration and pyometra were diagnosed in a 16-year-old maiden Welsh pony mare. Due to anatomical and surgical difficulties encountered throughout treatment, previously reported techniques including both per-vaginum removal of fetal remnants an...

  • Case Report
  • Open Access
1 Citations
2,302 Views
8 Pages

Ultrasound-Assisted Removal of a Wooden Foreign Body Embedded in the Neck

  • Daniele Vitali,
  • Pietro Orlando,
  • Giandomenico Maggiore,
  • Oreste Gallo and
  • Ilaria Bindi

19 December 2023

Objectives: The deep submucosal migration of ingested foreign bodies into the pharyngolaryngeal mucosa is a sporadic event, and its management can be very challenging. In the case of the failure of endoscopic retrieval, open surgical techniques are u...

  • Case Report
  • Open Access
2 Citations
5,599 Views
8 Pages

Treatment of a Recurrent Pyometra by Surgical Uterine Drainage in a Main Coon Cat

  • Gianluca Martini,
  • Roberta Bucci,
  • Salvatore Parrillo,
  • Augusto Carluccio and
  • Maria Carmela Pisu

15 January 2023

Pyometra is a uterine disease typical of the luteal phase of the estrus cycle. For selected patients, such as breeding subjects, ovariohysterectomy is not a valid resolutive option. Medical treatments involving cloprostenol and aglepristone have been...

  • Article
  • Open Access
4 Citations
8,746 Views
11 Pages

A 26-Year Experience in Chorionic Villus Sampling Prenatal Genetic Diagnosis

  • Paula Jorge,
  • Maria Manuela Mota-Freitas,
  • Rosário Santos,
  • Maria Luz Silva,
  • Gabriela Soares and
  • Ana Maria Fortuna

24 July 2014

This report describes the trends of chorionic villus sampling (CVS) referred for prenatal genetic diagnosis in the past two and a half decades in a Portuguese Center. Our cohort of 491 CVS was mostly performed by the transcervical method at the 12th...

  • Review
  • Open Access
7 Citations
4,963 Views
18 Pages

The Endoscopic Management of Zenker’s Diverticulum: A Comprehensive Review

  • Giuseppe Dell’Anna,
  • Ernesto Fasulo,
  • Jacopo Fanizza,
  • Rukaia Barà,
  • Edoardo Vespa,
  • Alberto Barchi,
  • Paolo Cecinato,
  • Lorenzo Fuccio,
  • Vito Annese and
  • Alberto Malesci
  • + 3 authors

27 September 2024

Zenker’s Diverticulum (ZD) is the most common hypopharyngeal diverticulum; however, it is often underdiagnosed. It results from the herniation of the mucosa and submucosa through Killian’s Triangle. Dysphagia is the primary symptom, occur...

  • Article
  • Open Access
16 Citations
6,430 Views
7 Pages

Factors Affecting Pregnancy Rate Following Fallopian Tube Recanalization in Women with Proximal Fallopian Tube Obstruction

  • Mamoon H. Al-Omari,
  • Nael Obeidat,
  • Mwafiq Elheis,
  • Ruba A. Khasawneh and
  • Maha M. Gharaibeh

Fallopian tube obstruction is a major cause of female infertility. We aimed to evaluate the factors potentially affecting pregnancy rate following fallopian tube recanalization (FTR) in infertile women with proximal fallopian tube obstruction. Data w...

  • Case Report
  • Open Access
5 Citations
3,235 Views
8 Pages

Parapharyngeal Metastasis of Papillary Carcinoma of Thyroid Gland: A Case Report and a Review of the Literature

  • Massimo Campagnoli,
  • Davide Masnaghetti,
  • Maria Silvia Rosa,
  • Edoardo Paganelli,
  • Massimiliano Garzaro and
  • Paolo Aluffi Valletti

Papillary carcinoma is the most frequently encountered differentiated thyroid carcinoma. Usually, metastasis occurs along lymphatic pathways in the central compartment and along the jugular chain. Nevertheless, lymph node metastasis in the parapharyn...

  • Article
  • Open Access
1,755 Views
14 Pages

19 January 2025

Studies in humans indicate that certain Chlamydia trachomatis serovars are more pathogenic than others. Specifically, several studies concluded that serovars from the C-complex are more pathogenic than those from the B-complex, although there are rep...

  • Article
  • Open Access
10 Citations
4,226 Views
14 Pages

Immunogenicity and Protective Capacity of a Virus-like Particle Vaccine against Chlamydia trachomatis Type 3 Secretion System Tip Protein, CT584

  • Everett Webster,
  • Kyra W. Seiger,
  • Susan B. Core,
  • Amanda L. Collar,
  • Hannah Knapp-Broas,
  • June Graham,
  • Muskan Shrestha,
  • Sarah Afzaal,
  • William M. Geisler and
  • Cosette M. Wheeler
  • + 3 authors

12 January 2022

An effective vaccine against Chlamydia trachomatis is urgently needed as infection rates continue to rise and C. trachomatis causes reproductive morbidity. An obligate intracellular pathogen, C. trachomatis employs a type 3 secretion system (T3SS) fo...

  • Article
  • Open Access
10 Citations
4,137 Views
8 Pages

Risk Factors of Descending Necrotizing Mediastinitis in Deep Neck Abscesses

  • Chih-Yu Hu,
  • Kuang-Hsu Lien,
  • Shih-Lung Chen and
  • Kai-Chieh Chan

30 November 2022

Background and Objectives: Cervical space infection could also extend to the mediastinum due to the anatomical vicinity. The mortality rate of descending necrotizing mediastinitis is 85% if untreated. The aim of this study was to identify risk factor...

  • Article
  • Open Access
1,246 Views
19 Pages

Development and Characterisation of a Microneedle Sensor for Intrapartum Fetal Monitoring

  • J. M. Mitchell,
  • C. V. Thatte,
  • R. Sebastian,
  • C. O’Mahony,
  • R. A. Greene,
  • J. R. Higgins,
  • P. Galvin,
  • F. P. McCarthy and
  • S. R. Teixeira

8 August 2025

This study presents the in vitro and preliminary ex vivo development of a novel microneedle-based pH sensor for continuous intrapartum fetal monitoring. The objective was to evaluate the feasibility of using microneedle sensors to monitor fetal pH du...

  • Article
  • Open Access
31 Citations
3,959 Views
14 Pages

Multiparametric Study of Antioxidant Effect on Ram Sperm Cryopreservation—From Field Trials to Research Bench

  • Marta F. Riesco,
  • Mercedes Alvarez,
  • Luis Anel-Lopez,
  • Marta Neila-Montero,
  • Cristina Palacin-Martinez,
  • Rafael Montes-Garrido,
  • Juan Carlos Boixo,
  • Paulino de Paz and
  • Luis Anel

23 January 2021

The optimization of sperm cryopreservation protocols in ram is a feasible tool to reinforce artificial insemination technologies considering the desirable application of sperm by vaginal/cervical or transcervical deposition. Cryopreservation provokes...

  • Article
  • Open Access
2 Citations
2,939 Views
17 Pages

High-Throughput In Vitro Screening Identified Nemadipine as a Novel Suppressor of Embryo Implantation

  • Xian Chen,
  • Sudini Ranshaya Fernando,
  • Yin-Lau Lee,
  • William Shu-Biu Yeung,
  • Ernest Hung-Yu Ng,
  • Raymond Hang-Wun Li and
  • Kai-Fai Lee

Current contraceptive methods interfere with folliculogenesis, fertilization, and embryo implantation by physical or hormonal approaches. Although hormonal contraceptive pills are effective in regulating egg formation, they are less effective in prev...

  • Review
  • Open Access
830 Views
12 Pages

Tumors of the Parapharyngeal Space Presenting with Obstructive Sleep Apnea: A Case Report and Literature Review

  • Luca Cerri,
  • Francesco Giombi,
  • Michele Cerasuolo,
  • Gian Marco Pace,
  • Anna Losurdo,
  • Giuseppe Lunardi,
  • Francesco Grecchi,
  • Elena Volpini and
  • Luca Malvezzi

28 July 2025

Introduction: Obstructive sleep apnea syndrome (OSAS) is caused by anatomical and non-anatomical factors which lead to upper airway (UA) obstruction during sleep. Intrinsic UA collapse is the most frequent determinant of OSA. In the era of personaliz...

  • Article
  • Open Access
1 Citations
978 Views
16 Pages

Surgery for T1/2N0 Oropharyngeal Carcinoma Is a Better Treatment Option than Radiotherapy—A Long-Term Follow-Up Study from a Single Japanese High-Volume Cancer Center

  • Masahiro Rokugo,
  • Takeshi Shinozaki,
  • Ryo Ishii,
  • Yusuke Ito,
  • Shingo Sakashita,
  • Genichiro Ishii,
  • Takenori Ogawa,
  • Yukio Katori,
  • Kazuto Matsuura and
  • Ryuichi Hayashi

31 May 2025

Background: The proportion of oropharyngeal cancers, especially those that are HPV-associated, is increasing, and both surgery and RT are considered effective initial treatments for early-stage oropharyngeal cancer, regardless of p16 status. However,...

  • Article
  • Open Access
6 Citations
2,885 Views
11 Pages

12 August 2023

Background and Objectives: Surgical treatment for primary hyperparathyroidism (PHPT) has evolved from bilateral exploration through a long transcervical incision to focused parathyroidectomy with a minimal incision above the pathologic gland. Recentl...

  • Systematic Review
  • Open Access
1,734 Views
28 Pages

Topical Dinoprostone vs. Foley’s Catheter: A Systematic Review and Meta-Analysis of Cervical Ripening Approaches

  • Amal Yaseen Zaman,
  • Howaida Amin Hassan,
  • Nageshwar Venkatesh Reddy,
  • Farzana Begum,
  • Samar Ahmed Mahmoud,
  • Hayat Alghamdi,
  • Naglaa Kamel AbdAllah Hussein,
  • Mariam Yousif Elhussain,
  • Soad Mohamed Alnassry and
  • Magda Mubarak Merghani
  • + 3 authors

Background and aim: Labor induction is increasing in obstetric practice. In women with an unfavorable cervix, cervical ripening is required for successful induction. We conducted this review to compare the effectiveness and tolerance of two intervent...

  • Article
  • Open Access
2 Citations
2,187 Views
9 Pages

Enhancing Patient Selection in Stage IIIA-IIIB NSCLC: Invasive Lymph Node Restaging after Neoadjuvant Therapy

  • Robert Kwiatkowski,
  • Marcin Zieliński,
  • Jarosław Paluch,
  • Jadwiga Gabor and
  • Andrzej Swinarew

12 January 2024

Restaging of mediastinal lymph nodes plays a crucial role in the multimodal treatment of stage IIIA Non-Small-Cell Lung Cancer (NSCLC). This study aimed to assess the impact of restaging using endobronchial ultrasound (EBUS), endoesophageal ultrasoun...

  • Case Report
  • Open Access
1,707 Views
16 Pages

Ectopic Mediastinal Thyroid: A Crossroad Between a Multi-Layered Endocrine Perspective and a Contemporary Approach in Thoracic Surgery

  • Claudiu Nistor,
  • Mihai-Lucian Ciobica,
  • Oana-Claudia Sima,
  • Anca-Pati Cucu,
  • Florina Vasilescu,
  • Lucian-George Eftimie,
  • Dana Terzea,
  • Mihai Costachescu,
  • Adrian Ciuche and
  • Mara Carsote

25 October 2024

An ectopic thyroid (ET) involves numerous scenarios of detection and outcomes, while its current management is not standardised. A mediastinal ET (MET) represents a low index of suspicion. In this paper, we introduce a 47-year-old female who was acci...