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396 Results Found

  • Article
  • Open Access
16 Citations
3,026 Views
11 Pages

(1) Background: We have sometimes experienced patients with vasospastic angina (VSA) who presented multi-vessel spasm (MVS) on coronary angiography and spasm provocation test (SPT). However, the clinical characteristics of VSA patients with MVS and t...

  • Article
  • Open Access
2 Citations
1,016 Views
13 Pages

Retrospective Analysis of Angiographic Radial Artery Spasm Predictors

  • Adrian Sebastian Zus,
  • Simina Crișan,
  • Silvia Luca,
  • Daniel Nișulescu and ,
  • Mihaela-Daniela Valcovici,
  • Oana Pătru,
  • Mihai-Andrei Lazăr,
  • Cristina Văcărescu,
  • Dan Gaiță and
  • Constantin-Tudor Luca
  • + 5 authors+ 0 author

16 November 2025

Background: Radial artery spasm remains a frequent complication during transradial coronary and peripheral angiography. Despite its impact on procedural success and patient discomfort, consistent predictors remain elusive, as does a standard definiti...

(This article belongs to the Special Issue Management of Ischemia and Heart Failure—3rd Edition)
  • Article
  • Open Access
2 Citations
2,409 Views
12 Pages

Which Coronary Artery Should Be Preferred for Starting the Coronary Spasm Provocation Test?

  • Hiroki Teragawa,
  • Yuko Uchimura,
  • Chikage Oshita,
  • Yu Hashimoto and
  • Shuichi Nomura

17 October 2023

Background: The spasm provocation test (SPT) is a critical test for diagnosing vasospastic angina (VSA). However, the choice of vessel to be preferred for initiating the SPT—the right coronary artery (RCA) or the left coronary artery (LCA)&mdas...

(This article belongs to the Collection Advances in Coronary Heart Disease)
  • Review
  • Open Access
1 Citations
1,923 Views
26 Pages

Coronary Artery Spasm in Patients with Type 2 Diabetes Mellitus

  • Theodor Iulian Matei,
  • Minerva Codruta Badescu,
  • Alexandru Dan Costache,
  • Ionuț Tudorancea and ,
  • Ionela Lăcrămioara Șerban,
  • Sandu Cucută,
  • Bianca-Ana Dmour,
  • Raluca Daria Mitea,
  • Radu-George Ciorap and
  • Irina Iuliana Costache-Enache
  • + 6 authors+ 1 author

19 February 2026

Cardiovascular disease and diabetes mellitus have now reached pandemic proportions, and their association has become very common. Some patients with coronary artery disease and diabetes remain symptomatic, with chest pain present despite the implemen...

(This article belongs to the Special Issue Cardiovascular Diseases: From Basic Research to Clinical Application—3rd Edition)
  • Case Report
  • Open Access
1 Citations
645 Views
5 Pages

Paradoxical Coronary Spasm After Intracoronary Nitrogylcerin Injection

  • Marco Robertoa,
  • Cedric Vuilleb and
  • Edoardo De Benedettic

16 November 2016

Vasospastic angina is a clinical disorder primarily attributable to coronary artery spasm and typically characterised by a history of rest angina that promptly responds to short-acting nitrates. In this case report, we describe a 72-year-old man affe...

  • Article
  • Open Access
1 Citations
1,586 Views
11 Pages

Should the Right Coronary Artery Be Routinely Assessed During Provocative Spasm Testing?

  • Olivia Girolamo,
  • Rosanna Tavella,
  • David Di Fiore,
  • Abdul Sheikh and ,
  • Sivabaskari Pasupathy,
  • Eng Lee Ooi,
  • Jessica A. Marathe,
  • Christopher Zeitz and
  • John F. Beltrame
  • + 4 authors+ 0 author

18 February 2025

Background/Objectives: The diagnosis of coronary artery spasm (CAS) frequently requires invasive provocation testing, typically utilising acetylcholine (ACh). Although the left coronary artery (LCA) is routinely assessed as a part of the testing prot...

(This article belongs to the Special Issue Advances in Clinical Practice and Personalized Approaches in Cardiovascular Disease)
  • Review
  • Open Access
9 Citations
10,761 Views
35 Pages

Coronary Artery Spasm: From Physiopathology to Diagnosis

  • Ilinca Savulescu-Fiedler,
  • Radu Octavian Baz,
  • Radu Andrei Baz,
  • Cristian Scheau and
  • Andrei Gegiu

3 April 2025

Coronary artery spasm (CAS) is a reversible vasoconstriction of normal or atherosclerotic epicardial coronary arteries with a subsequent reduction in myocardial blood flow, leading to myocardial ischemia, myocardial infarction, severe arrhythmias, or...

(This article belongs to the Special Issue Coronary Artery Disease: Pathophysiological Mechanisms, Imaging Modalities and Therapeutic Implications)
  • Article
  • Open Access
5 Citations
4,174 Views
12 Pages

7 October 2023

(1) Background: In cases of hemifacial spasm (HFS), there are various patterns related to the vascular compression of the facial nerve, including a very rare form that is seen when the offending vessel penetrates the facial nerve. However, there have...

(This article belongs to the Special Issue Novel Diagnostic and Therapeutic Approaches in Temporomandibular Disorders (TMDs) and Myofascial Pain)
  • Case Report
  • Open Access
1 Citations
271 Views
2 Pages

Coronary Spasm Provocation Testing: Still Useful?

  • Felipe Andres Molina Jaque,
  • Andrew Christopher Rahardja,
  • Timothy Watson and
  • Mark Webster

This short and interesting case demonstrates very aptly the potential clinical utility of provocation testing for coronary artery spasm and briefly discusses the uncertainty encountered in interpreting the test.

  • Article
  • Open Access
2 Citations
2,664 Views
12 Pages

Background: Multi-vessel spasm (MVS) has a prognostic impact in patients with vasospastic angina (VSA). Thus, the presence of coronary spasm in both the left coronary artery (LCA) and right coronary artery (RCA) should be assessed through the spasm p...

(This article belongs to the Section Cardiovascular Clinical Research)
  • Article
  • Open Access
5 Citations
2,523 Views
10 Pages

21 September 2022

Background: Epicardial spasm (ES) phenotypes may be related to the prognosis in patients with coronary spastic angina. Objectives: The purpose of this study was to elucidate the relationship between angiographic coronary vasomotor responses to intrac...

(This article belongs to the Collection Advances in Coronary Heart Disease)
  • Case Report
  • Open Access
2 Citations
3,491 Views
9 Pages

A Case Report of Hemifacial Spasm Caused by Vestibular Schwannoma and Literature Review

  • Xiaomin Cai,
  • Yinda Tang,
  • Hua Zhao,
  • Zheng Chen and ,
  • Haopeng Wang,
  • Wanchun Zhu and
  • Shiting Li
  • + 2 authors+ 0 author

5 October 2022

Background: Most cases of hemifacial spasm result from mechanical compression at the root exit zone of the facial nerve by vascular loops, and only a few cases are caused by vestibular schwannoma. Case presentation: We report a case of symptomatic he...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Review
  • Open Access
20 Citations
9,802 Views
16 Pages

Cellular Mechanisms of Coronary Artery Spasm

  • Beata Franczyk,
  • Jill Dybiec,
  • Weronika Frąk,
  • Julia Krzemińska and ,
  • Joanna Kućmierz,
  • Ewelina Młynarska,
  • Magdalena Szlagor,
  • Magdalena Wronka and
  • Jacek Rysz
  • + 4 authors+ 0 author

21 September 2022

Coronary artery spasm (CAS) is a reversible phenomenon caused by spontaneous excessive vascular smooth muscle contractility and vascular wall hypertonicity, which results in partial or complete closure of the lumen of normal or atherosclerotic corona...

(This article belongs to the Special Issue Cellular Mechanisms of Cardiovascular Disease)
  • Opinion
  • Open Access
11 Citations
12,597 Views
7 Pages

Clinical Application of Botulinum Toxin for Hemifacial Spasm

  • Chang-Kyu Park,
  • Seung-Hoon Lim and
  • Kwan Park

17 August 2023

Hemifacial spasm is typically caused by contact between the facial nerve and blood vessels. Microvascular decompression, a treatment that directly addresses this pathogenesis, is often considered the most effective treatment method. However, surgery...

(This article belongs to the Section Physiology and Pathology)
  • Case Report
  • Open Access
4,541 Views
6 Pages

Spasm of Near Reflex in a Patient with Autism Spectrum Disorder: A Case Report

  • Satoshi Ueki,
  • Yukari Hasegawa,
  • Tetsuhisa Hatase,
  • Takako Hanyu and ,
  • Jun Egawa,
  • Atsushi Miki and
  • Takeo Fukuchi
  • + 2 authors+ 0 author

8 August 2023

Spasm of near reflex (SNR) involves intermittent spasm of one or more of the three near reflex components. Psychiatric disorders are one cause of SNR. We describe a patient with SNR diagnosed with autism spectrum disorder (ASD). A 36-year-old male wi...

  • Review
  • Open Access
44 Citations
17,056 Views
11 Pages

Botulinum Toxin for the Treatment of Hemifacial Spasm: An Update on Clinical Studies

  • Nicola Tambasco,
  • Marta Filidei,
  • Pasquale Nigro,
  • Lucilla Parnetti and
  • Simone Simoni

9 December 2021

Hemifacial spasm (HFS) is a movement disorder characterized by involuntary contractions of the facial muscles innervated by the seventh cranial nerve. Generally, it is associated with a poor quality of life due to social embarrassment and can lead to...

(This article belongs to the Special Issue Botulinum Toxin in the Movement Disorders Clinic: State of the Art)
  • Article
  • Open Access
19 Citations
3,736 Views
14 Pages

27 December 2021

Background: In the clinical setting; the microvascular vasodilatory function test (MVFT) with a pressure wire has been used in ischaemia patients with non-obstructive coronary arteries (INOCA), including vasospastic angina (VSA) and microvascular ang...

(This article belongs to the Special Issue Coronary Syndrome: Clinical Treatment, Prevention and Management for Better Outcomes)
  • Article
  • Open Access
355 Views
13 Pages

Early Risk Stratification and Time-to-Cure Analysis in Patients with Residual Hemifacial Spasm After Microvascular Decompression

  • Siyi Liu,
  • Tao Du,
  • Feng Hou,
  • Zaiying Jiang and ,
  • Liu He,
  • Yunjian Huang,
  • Bing Ni,
  • Xueyuan Wang,
  • Yunpeng Wang and
  • Hongwei Zhu
  • + 5 authors+ 0 author

16 September 2026

Background/Objectives: Microvascular decompression (MVD) is an effective treatment for hemifacial spasm (HFS), but some patients have residual spasms after surgery. Some later achieve delayed cure, whereas others have persistent HFS, making reoperati...

(This article belongs to the Special Issue New Trends and Technologies in Modern Neurosurgery: 2nd Edition)
  • Review
  • Open Access
20 Citations
7,158 Views
12 Pages

24 July 2023

This review article discusses the clinical significance of intraoperative neurophysiological monitoring (IONM), provides recommendations for monitoring protocols, and considers the interpretation of results in microvascular decompression (MVD) for he...

(This article belongs to the Section Physiology and Pathology)
  • Review
  • Open Access
28 Citations
5,975 Views
16 Pages

Radial Artery Spasm—A Review on Incidence, Prevention and Treatment

  • Adrian Sebastian Zus,
  • Simina Crișan,
  • Silvia Luca,
  • Daniel Nișulescu and ,
  • Mihaela Valcovici,
  • Oana Pătru,
  • Mihai-Andrei Lazăr,
  • Cristina Văcărescu,
  • Dan Gaiță and
  • Constantin-Tudor Luca
  • + 5 authors+ 0 author

29 August 2024

Radial artery spasm (RAS) is a common complication associated with transradial access (TRA) for coronary interventions, particularly affecting elderly patients in whom radial access is preferred due to its benefits in reducing bleeding complications,...

(This article belongs to the Special Issue Vascular Malformations: Diagnosis and Management)
  • Article
  • Open Access
6 Citations
2,989 Views
13 Pages

Patient Characteristics and Real-World Use of Botulinum Toxins for the Treatment of Cervical Dystonia, Blepharospasm, and Hemifacial Spasm

  • Michael A. Hast,
  • Amanda M. Kong,
  • Shaina Desai,
  • Soo Back and ,
  • Sahar Syed and
  • Jordan Holmes
  • + 1 author+ 0 author

16 August 2024

Movement disorders such as cervical dystonia, blepharospasm, and hemifacial spasm negatively impact the quality of life of people living with these conditions. Botulinum toxin (BoNT) injections are commonly used to treat these disorders. We sought to...

  • Article
  • Open Access
10 Citations
17,119 Views
9 Pages

23 May 2022

The aim of this study was to show our therapeutic outcome of botulinum injection to the facial muscles and thereby to find the best therapeutic concept which should be embraced. The decision to treat the lower eyelid with 1-point or 2-points injectio...

  • Article
  • Open Access
4 Citations
3,776 Views
9 Pages

Predicting Early Loss of Lateral Spread Response before Decompression in Hemifacial Spasm Surgery

  • Ryan Wing-Yuk Chan,
  • Yung-Hsiao Chiang,
  • Yi-Yu Chen,
  • Yi-Chen Chen and ,
  • Jiann-Her Lin and
  • Yi-Syue Tsou
  • + 1 author+ 0 author

27 December 2021

Recent studies have shown the evocation of lateral spread response (LSR) due to the compression of the facial nerve in hemifacial spasm (HFS). Intraoperative monitoring (IOM) of LSR could help locate neurovascular conflicts and confirm adequate micro...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
10 Citations
3,333 Views
9 Pages

16 March 2021

This study aimed to determine the long-term quality of life (QoL) in hemifacial spasm (HFS) patients after treating with Abo-botulinum toxin A (Abo-BTX). The study assessed the disease-specific QoL (hemifacial spasm questionnaire 30 items; HFS 30), t...

(This article belongs to the Special Issue Enhancing the Effect of Botulinum Toxin in Neurology, Neurorehabilitation and Pain Medicine)
  • Article
  • Open Access
14 Citations
4,115 Views
11 Pages

13 September 2023

Hemifacial spasm (HFS) is a hyperactive cranial neuropathy, and it has been well established that the cause of primary HFS is compression on the root exit zone (REZ) of the facial–vestibulocochlear nerve complex (CN VII-VIII) by a vessel or ves...

(This article belongs to the Special Issue Novel Diagnostic and Therapeutic Approaches in Temporomandibular Disorders (TMDs) and Myofascial Pain)
  • Review
  • Open Access
9 Citations
4,232 Views
12 Pages

29 August 2023

Hemifacial spasm (HFS) is a rare disorder characterized by involuntary facial muscle contractions. The primary cause is mechanical compression of the facial nerve by nearby structures. Lateral spread response (LSR) is an abnormal muscle response obse...

(This article belongs to the Special Issue Novel Diagnostic and Therapeutic Approaches in Temporomandibular Disorders (TMDs) and Myofascial Pain)
  • Case Report
  • Open Access
1,081 Views
3 Pages

29 October 2014

We present an illustrative case report of the mid-vessel left anterior descending (LAD) coronary artery spasm, which has been enhanced by straightening of the tortuous LAD segment with a guidewire (‘‘accordion effect’’) thus resistant to intracoronar...

  • Case Report
  • Open Access
305 Views
12 Pages

7 October 2026

Background and Clinical Significance: Multivessel coronary artery spasm (CAS) is an uncommon, high-risk form of vasospastic angina that can produce transient ST-segment elevation mimicking acute myocardial infarction. Evidence to guide management whe...

(This article belongs to the Section Cardiology/Cardiovascular Medicine)
  • Article
  • Open Access
1 Citations
1,103 Views
26 Pages

Background: In the last few decades, microvascular decompression has been proven to be one of the best therapeutic options in the management of neurovascular compression syndromes, especially trigeminal neuralgia, hemifacial spasm, and glossopharynge...

(This article belongs to the Section Pain Research)
  • Case Report
  • Open Access
2,143 Views
13 Pages

Background: Alemtuzumab is a recombinant DNA-derived humanized monoclonal antibody directed against the 21–28 kd cell surface glycoprotein, CD52. Alemtuzumab is used as an organ anti-rejection therapy in transplant recipients. Neuro-ophthalmic...

(This article belongs to the Section Solid Organ Transplantation)
  • Article
  • Open Access
446 Views
21 Pages

Sedation Strategy, Procedural Comfort, and Clinically Detected Radial Artery Spasm During Transradial Coronary Angiography: A Prospective Observational Study

  • Uğur Karagöz,
  • Senem Girgin,
  • Mehmet Ali Coşar,
  • Fahrettin Tuğrul Çitekçi and ,
  • Tolunay Demirbaş,
  • Ecem Büger,
  • Büşra Tozduman,
  • Sadık Volkan Emren and
  • Murat Aksun
  • + 4 authors+ 0 author

1 September 2026

Background/Objectives: Radial artery spasm (RAS) is the most common periprocedural complication of transradial coronary angiography (TRA) and is identified clinically, from patient-reported forearm pain and operator-perceived catheter resistance, rat...

(This article belongs to the Special Issue Advances in Interventional Cardiology: From Access to Outcomes)
  • Article
  • Open Access
4 Citations
5,453 Views
9 Pages

A New Finding on Magnetic Resonance Imaging for Diagnosis of Hemifacial Spasm with High Accuracy and Interobserver Correlation

  • Guilherme Finger,
  • Kyle C. Wu,
  • Joshua Vignolles-Jeong,
  • Saniya S. Godil and ,
  • Ben G. McGahan,
  • Daniel Kreatsoulas,
  • Mohammad T. Shujaat,
  • Luciano M. Prevedello and
  • Daniel M. Prevedello
  • + 4 authors+ 0 author

9 October 2023

Among patients with clinical hemifacial spasm (HFS), imaging exams aim to identify the neurovascular conflict (NVC) location. It has been proven that the identification in the preoperative exam increases the rate of surgical success. Despite the desc...

(This article belongs to the Special Issue Advances in Skull Base Tumor Surgery: The Practical Pearls)
  • Review
  • Open Access
15 Citations
7,848 Views
35 Pages

Coronary Artery Spasm-Related Heart Failure Syndrome: Literature Review

  • Ming-Jui Hung,
  • Chi-Tai Yeh,
  • Nicholas G. Kounis,
  • Ioanna Koniari and ,
  • Patrick Hu and
  • Ming-Yow Hung
  • + 1 author+ 0 author

Although heart failure (HF) is a clinical syndrome that becomes worse over time, certain cases can be reversed with appropriate treatments. While coronary artery spasm (CAS) is still underappreciated and may be misdiagnosed, ischemia due to coronary...

(This article belongs to the Special Issue New Advances in Thrombosis)
  • Article
  • Open Access
696 Views
12 Pages

Pontine Microtubular Signal Intensity in Hemifacial Spasm: Association with Outcome After Microvascular Decompression Surgery

  • Hyun Seok Lee,
  • Hong Gee Roh,
  • Won-Jin Moon,
  • Change-Hee Kim and ,
  • Kwan Park and
  • Jin Woo Choi
  • + 1 author+ 0 author

14 April 2026

Background: We aimed to investigate the prevalence and clinical significance of pontine microtubular signal intensity (MSI), presumed dilated perivascular or perineural spaces, in patients with hemifacial spasm (HFS) using high-resolution MRI using p...

(This article belongs to the Special Issue Advances in Vascular Medicine: From Endovascular Innovations to Pathophysiological Insights)
  • Article
  • Open Access
13 Citations
2,215 Views
9 Pages

Gender Differences in the Impact of Plasma Xanthine Oxidoreductase Activity on Coronary Artery Spasm

  • Ken Watanabe,
  • Tetsu Watanabe,
  • Yoichiro Otaki,
  • Takayo Murase and ,
  • Takashi Nakamura,
  • Shigehiko Kato,
  • Harutoshi Tamura,
  • Satoshi Nishiyama,
  • Hiroki Takahashi and
  • Masafumi Watanabe
  • + 6 authors+ 1 author

26 November 2021

Xanthine oxidoreductase (XOR) is the rate-limiting enzyme in uric acid (UA) production that plays a pivotal role in generating oxidative stress. Gender differences in the impact of plasma XOR activity on coronary artery spasm (CAS) remain unclear. We...

(This article belongs to the Special Issue Coronary Syndrome: Clinical Treatment, Prevention and Management for Better Outcomes)
  • Article
  • Open Access
747 Views
12 Pages

23 February 2026

Objectives: Radial artery spasm (RAS) is a common complication of transradial coronary angiography that may adversely affect procedural success and patient comfort. This study aimed to evaluate clinical, procedural, and anthropometric factors associa...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
1 Citations
1,589 Views
13 Pages

3 March 2026

Coronary artery spasm (CAS) is a common endotype in patients with angina with non-obstructive coronary arteries. Pathophysiologically, the presence of CAS among arteries is not normal, as evidenced by several interacting mechanisms involving CAS deve...

(This article belongs to the Special Issue Cardiovascular Diseases: From Basic Research to Clinical Application—3rd Edition)
  • Article
  • Open Access
483 Views
11 Pages

Background/Objectives: Radial artery spasm (RAS) is an important complication during transradial coronary angiography that may negatively affect procedural success and reduce patient comfort. The aim of this study was to comparatively evaluate the ef...

(This article belongs to the Special Issue Advanced Diagnostic Approaches in Cardiovascular Diseases: From Imaging to Biomarkers)
  • Opinion
  • Open Access
5 Citations
3,301 Views
11 Pages

22 August 2023

Brainstem auditory evoked potential (BAEP) testing during microvascular decompression (MVD) is very important in the treatment of hemifacial spasm (HFS). The reason for this is that the vestibulocochlear nerve is located immediately next to the facia...

(This article belongs to the Section Physiology and Pathology)
  • Article
  • Open Access
14 Citations
3,608 Views
25 Pages

Serum SELENBP1 and VCL Are Effective Biomarkers for Clinical and Forensic Diagnosis of Coronary Artery Spasm

  • Xinyi Lin,
  • Zijie Lin,
  • Xin Zhao,
  • Zheng Liu and ,
  • Chenchao Xu,
  • Bokang Yu,
  • Pan Gao,
  • Zhimin Wang,
  • Junbo Ge and
  • Liliang Li
  • + 6 authors+ 1 author

31 October 2022

Coronary artery spasm (CAS) plays an important role in the pathogenesis of many ischemic heart entities; however, there are no established diagnostic biomarkers for CAS in clinical and forensic settings. This present study aimed to identify such seru...

(This article belongs to the Special Issue Cellular and Molecular Biology of Heart Diseases)
  • Article
  • Open Access
6 Citations
2,530 Views
8 Pages

22 January 2023

This study aimed to investigate mental illnesses among patients with hemifacial spasms (HFS) based on nationwide claims data from the South Korea Health Insurance Review and Assessment Service. In this retrospective study, we defined the HFS group as...

  • Article
  • Open Access
9 Citations
6,435 Views
10 Pages

16 October 2023

The purpose of this study was to investigate the outcome of microvascular decompression (MVD) in patients with hemifacial spasm (HFS) who have no definite radiological neurovascular compression (NVC). Sixteen HFS patients without radiological NVC on...

(This article belongs to the Section Physiology and Pathology)
  • Article
  • Open Access
5 Citations
3,997 Views
11 Pages

7 November 2022

The aim of this study was to investigate the frequency of hemorrhagic side effects of botulinum neurotoxin A injections (BoNT/A) for the treatment of benign essential blepharospasm (BEB) and hemifacial spasm (HFS) in patients taking antithrombotic dr...

(This article belongs to the Special Issue Botulinum Toxins: New Uses in the Treatment of Diseases)
  • Review
  • Open Access
2 Citations
813 Views
16 Pages

10 August 2026

Neurovascular compression syndromes (NVCS), including trigeminal neuralgia (TN) and hemifacial spasm (HFS), are characterized by disabling symptoms caused by vascular compression of cranial nerves. Although microvascular decompression is an establish...

  • Article
  • Open Access
6 Citations
3,129 Views
12 Pages

Impact of Opioid Analgesia and Inhalation Sedation Kalinox on Pain and Radial Artery Spasm during Transradial Coronary Angiography

  • Caroline Birgy,
  • Antonin Trimaille,
  • Nathan Messas,
  • Jessica Ristorto and ,
  • Anas Kayali,
  • Benjamin Marchandot,
  • Thomas Cardi,
  • Sébastien Hess,
  • Marion Kibler and
  • Olivier Morel
  • + 7 authors+ 2 authors

25 August 2020

With respect to the transfemoral approach, transradial procedures enable a drastic reduction of bleeding events and are associated with a reduction of mortality. Radial artery spasm (RAS) is one of the most common complications and may lead to patien...

(This article belongs to the Special Issue Clinical Research of Percutaneous Coronary Intervention)
  • Review
  • Open Access
21 Citations
4,777 Views
11 Pages

Factors Related to Hemifacial Spasm Recurrence in Patients Undergoing Microvascular Decompression—A Systematic Review and Meta-Analysis

  • Grazia Menna,
  • Marco Battistelli,
  • Alessandro Rapisarda,
  • Alessandro Izzo and ,
  • Manuela D’Ercole,
  • Alessandro Olivi and
  • Nicola Montano
  • + 2 authors+ 0 author

There is a lack of knowledge about the factors associated with the recurrence of hemifacial spam (HFS) following an initially successful microvascular decompression (MVD) surgery. The aim of the present study was to systematically review the pertinen...

(This article belongs to the Special Issue Improving Outcomes and Preventing Complications in Cranial Base Surgery)
  • Article
  • Open Access
6 Citations
7,106 Views
10 Pages

3 March 2022

Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy and early childhood. They can be caused by multiple etiologies. Structural abnormalities represent an important cause of infantile spasms. Brain magnetic reson...

  • Article
  • Open Access
5 Citations
2,915 Views
19 Pages

Phosphorylated CPI-17 and MLC2 as Biomarkers of Coronary Artery Spasm–Induced Sudden Cardiac Death

  • Yiming Dong,
  • Jianfeng Wang,
  • Chenteng Yang,
  • Junxia Bao and ,
  • Xia Liu,
  • Hao Chen,
  • Xiaojing Zhang,
  • Weibo Shi,
  • Lihua Zhang and
  • Guozhong Zhang
  • + 10 authors+ 5 authors

Coronary artery spasm (CAS) plays an important role in the pathogeneses of various ischemic heart diseases and has gradually become a common cause of life-threatening arrhythmia. The specific molecular mechanism of CAS has not been fully elucidated,...

(This article belongs to the Special Issue Molecular Biology in Forensic Science: Past, Present and Future, 2nd Edition)
  • Article
  • Open Access
2 Citations
2,895 Views
9 Pages

14 August 2025

Hemifacial spasm (HFS) is a cranial nerve disorder characterized by involuntary contractions of muscles innervated by the facial nerve. Botulinum toxin type A (BoNT-A) is widely used for symptom control. Although local diffusion is well established,...

(This article belongs to the Special Issue Advances in the Treatment of Movement Disorders with Botulinum Toxins)
  • Article
  • Open Access
1 Citations
1,950 Views
12 Pages

Beyond Improvement of Motor Symptoms: Central Effects of Botulinum Toxin on Anxiety and Depression in Focal Dystonia, Hemifacial Spasm, and Blepharospasm

  • Tihana Gilman Kuric,
  • Zvonimir Popovic,
  • Sara Matosa,
  • Eleonora Strujic and ,
  • Ivana Gacic,
  • Tea Mirosevic Zubonja,
  • Stjepan Juric,
  • Melita Pecek Prpic,
  • Vera Jelusic and
  • Svetlana Tomic
  • + 6 authors+ 1 author

25 January 2026

Cervical dystonia (CD), blepharospasm (BSP), and idiopathic hemifacial spasm (HFS) are focal hyperkinetic movement disorders with distinct underlying mechanisms. While CD and BSP involve central network dysfunctions within the basal ganglia-thalamo-c...

(This article belongs to the Section Bacterial Toxins)

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