Management of Ischemia and Heart Failure—3rd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 38

Special Issue Editor


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Guest Editor
Cardiology Department, “Victor Babes” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041 Timisoara, Romania
Interests: heart failure; acute coronary syndrome; speckle tracking; tissue Doppler imaging
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are grateful to the researchers who contributed to the first and second editions of this Special Issue, linked below:

Management of Ischemia and Heart Failure: https://www.mdpi.com/journal/life/special_issues/ischemia_heart

Management of Ischemia and Heart Failure—2nd Edition: https://www.mdpi.com/journal/life/special_issues/74677OH137

We are pleased to announce the upcoming publication of the latest edition of our Special Issue, entitled “Management of Ischemia and Heart Failure—3rd Edition”.

Heart disease is the number one cause of death worldwide, within which myocardial ischemia and heart failure are some of the most important entities. Heart failure is a complex syndrome responsible for high rates of death and hospitalization. Ischemic heart disease is one of the most frequent causes of heart failure, and is normally attributed to coronary artery disease, defined by the presence of one or more obstructive plaques, which restrict coronary blood flow, causing myocardial ischemia and consequent heart failure. Coronary microvascular dysfunction results in an inability of coronary circulation to satisfy myocardial metabolic demands due to the imbalance of coronary blood flow regulatory mechanisms, including in ion channels, leading to the development of hypoxia, fibrosis and tissue death, which may determine a loss of myocardial function, even beyond the presence of atherosclerotic epicardial plaques. 

The aim of this Special Issue is to analyze and discuss major unsolved issues, from basic research to new medical and interventional options, to provide the best management strategies. Invited papers will focus on left ventricular remodeling, reperfusion injury (potential targets for treatment), prognostic markers, timing and tools to achieve optimal management in patients with ischemia and heart failure, and concepts to improve heart failure networks.

Dr. Cristian Mornoş
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • heart failure
  • myocardial ischemia
  • left ventricular remodeling
  • prognosis

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Published Papers

This special issue is now open for submission.
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