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Life
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Advances in Vascular Medicine: From Endovascular Innovations to Pathophysiological Insights
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Advances in Vascular Medicine: From Endovascular Innovations to Pathophysiological Insights

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 27 February 2026 | Viewed by 1233

Special Issue Editor

Dr. Edit Dósa

E-Mail Website
Guest Editor
Heart and Vascular Center, Semmelweis University, Városmajor Str. 68, 1122 Budapest, Hungary
Interests: endovascular therapy; carotid stenting; lower extremity interventions; restenosis predictors; venous interventions
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue titled “Advances in Vascular Medicine: From Endovascular Innovations to Pathophysiological Insights”, which aims to highlight the latest research and clinical advancements in vascular health. This Issue will provide a platform for interdisciplinary studies bridging endovascular therapies, diagnostic imaging, and mechanistic discoveries in vascular diseases.

We welcome original research articles and reviews that cover topics such as follows:

  • Endovascular innovations: Novel stent technologies, bioresorbable devices, robotic-assisted interventions, and image-guided therapies.
  • Vascular pathophysiology: Molecular mechanisms, biomarkers, genetic influences, and cellular pathways in atherosclerosis, aneurysms, and peripheral artery disease.
  • Translational and clinical studies: Evidence-based approaches to revascularization, thromboembolic management, and vascular complications of systemic diseases.
  • Emerging imaging techniques: Advances in intravascular ultrasound (IVUS), optical coherence tomography (OCT), and AI-enhanced diagnostics.

This Special Issue seeks to foster collaboration among interventional radiologists, vascular surgeons, cardiologists, and translational researchers. By integrating cutting-edge technology with fundamental science, we aim to advance precision medicine in vascular care.

Dr. Edit Dósa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • endovascular therapy
  • vascular pathophysiology
  • intravascular imaging
  • atherosclerosis
  • precision vascular medicine

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

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12 pages, 1127 KB  
Article
Randomized Controlled Trial of Patient Positioning and Operator Radiation Exposure During Lower Extremity Catheter Angiography
by Ákos Bérczi, Fanni Éva Szablics, Anita Nelli Simon, Gabriella Taba, Dóra Ágota Papp, Réka György, Ákos András Pataki, Artúr Hüttl, Balázs Nemes and Csaba Csobay-Novák
Life 2025, 15(9), 1433; https://doi.org/10.3390/life15091433 - 12 Sep 2025
Viewed by 686
Abstract
Digital subtraction angiography (DSA) remains an important reference modality for evaluating chronic limb-threatening ischemia (CLTI), with left transradial access (TRA) increasingly favored for its lower complication rates and patient comfort. Radiation safety for operators is paramount, yet the impact of patient positioning on [...] Read more.
Digital subtraction angiography (DSA) remains an important reference modality for evaluating chronic limb-threatening ischemia (CLTI), with left transradial access (TRA) increasingly favored for its lower complication rates and patient comfort. Radiation safety for operators is paramount, yet the impact of patient positioning on scatter radiation during lower limb diagnostic catheter angiography (CA) is understudied. This single-center randomized controlled trial evaluated whether head-first (HF) vs. feet-first (FF) supine patient orientation affects operator radiation exposure during lower extremity CA from left TRA. Between February and August 2024, 24 patients with CLTI were enrolled and randomized to HF or FF positions. Operator radiation exposure was measured using thermoluminescent dosimeters (TLDs) at the eye, chest, and left ring finger. Background radiation was subtracted. Procedures were standardized and performed by a single experienced interventional radiologist. Fluoroscopy time, dose area product (DAP), and contrast usage were recorded. No statistically significant differences were found between groups in patient BMI and procedural parameters. Patient positioning (HF vs. FF) did not significantly impact operator radiation exposure. A trend toward higher finger exposure in FF position suggests the need for optimized hand protection. These findings support flexible patient positioning without compromising operator safety, reinforcing adherence to ALARA principles. Full article
(This article belongs to the Special Issue Advances in Vascular Medicine: From Endovascular Innovations to Pathophysiological Insights)
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Review

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20 pages, 5081 KB  
Review
Hybrid Open and Endovascular Repair in Pararenal Abdominal Aortic Pseudoaneurysm—Literature Review and Case Presentation
by Vlad Anton Iliescu, Reza Nayyerani, Catalina Andreea Parasca, Pavel Platon, Catalin Baston, Bianca Morosanu and Ovidiu Stiru
Life 2025, 15(11), 1765; https://doi.org/10.3390/life15111765 - 18 Nov 2025
Viewed by 334
Abstract
Pararenal abdominal aortic aneurysm/pseudoaneurysms (PAAA/PAAP) are rare, high-risk complex aortic lesions involving the renal arteries. Management includes open surgical repair (OSR), endovascular aortic repair (EVAR), or hybrid repair, each with specific advantages and limitations. A review of the literature was performed to assess [...] Read more.
Pararenal abdominal aortic aneurysm/pseudoaneurysms (PAAA/PAAP) are rare, high-risk complex aortic lesions involving the renal arteries. Management includes open surgical repair (OSR), endovascular aortic repair (EVAR), or hybrid repair, each with specific advantages and limitations. A review of the literature was performed to assess treatment strategies and outcomes for PAAA and PAAP. A PubMed search using relevant MeSH terms identified 184 articles published in the last five years. After applying inclusion and exclusion criteria, 34 studies comprising 6460 patients with complex AAA/AAP were included for analysis. Treatment strategies were predominantly endovascular (79.4%), followed by open (5.8%) and hybrid approaches (2.9%) (11.7% have used EVAR or OSR in the same study). To emphasize difficulties in the management of this pathology, a case report of a large PAAP involving both renal arteries and occluded celiac trunk with retrograde flow from patent superior mesenteric artery (SMA) is presented. Given the complex anatomy and high surgical risk, hybrid treatment was chosen consisting of bilateral ilio-renal Dacron bypasses followed by ChEVAR (chimney stenting of the SMA), with favorable postoperative recovery. The management of PAAP requires an individualized, anatomy- and risk-adapted approach. Open surgical repair remains preferable for younger, low-risk patients for superior long-term durability, whereas endovascular repair offers lower perioperative morbidity in high-risk cohorts. Optimal outcomes are dependent on high-volume centers with multidisciplinary expertise. Full article
(This article belongs to the Special Issue Advances in Vascular Medicine: From Endovascular Innovations to Pathophysiological Insights)
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