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202 Results Found

  • Article
  • Open Access
6 Citations
7,720 Views
12 Pages

Capacitive Imaging for Skin Characterizations and Solvent Penetration Measurements

  • Xu Zhang,
  • Christos Bontozoglou,
  • Elena Chirikhina,
  • Majella E. Lane and
  • Perry Xiao

1 September 2018

Capacitive contact imaging has shown potential in measuring skin properties including hydration, micro relief analysis, as well as solvent penetration measurements. Through calibration, we can also measure the absolute permittivity of the skin, and f...

  • Article
  • Open Access
8 Citations
3,471 Views
20 Pages

Choosing an Optimal Solvent Is Crucial for Obtaining Cell-Penetrating Peptide Nanoparticles with Desired Properties and High Activity in Nucleic Acid Delivery

  • Abhijit Biswas,
  • Maria Maloverjan,
  • Kärt Padari,
  • Aare Abroi,
  • Margus Rätsep,
  • Sebastian K. T. S. Wärmländer,
  • Jüri Jarvet,
  • Astrid Gräslund,
  • Vambola Kisand and
  • Margus Pooga
  • + 1 author

Cell-penetrating peptides (CPPs) are highly promising transfection agents that can deliver various compounds into living cells, including nucleic acids (NAs). Positively charged CPPs can form non-covalent complexes with negatively charged NAs, enabli...

  • Article
  • Open Access
22 Citations
8,282 Views
20 Pages

Influence of Massage and Skin Hydration on Dermal Penetration Efficacy of Nile Red from Petroleum Jelly—An Unexpected Outcome

  • Vasudha Kaushik,
  • Yameera Ganashalingam,
  • Robert Schesny,
  • Christian Raab,
  • Soma Sengupta and
  • Cornelia M. Keck

The study aimed at comparing the influence of direct and indirect skin hydration as well as massage on the dermal penetration efficacy of active compounds. Nile red was used as a lipophilic drug surrogate and was incorporated into Vaseline (petroleum...

  • Review
  • Open Access
34 Citations
6,750 Views
25 Pages

Deep Eutectic Systems as Novel Vehicles for Assisting Drug Transdermal Delivery

  • Jinbao Wang,
  • Mingjian Li,
  • Langhuan Duan,
  • Yameng Lin,
  • Xiuming Cui,
  • Ye Yang and
  • Chengxiao Wang

In recent years, deep eutectic systems (DES) emerged as novel vehicles for facilitating the transdermal delivery of various drugs, including polysaccharides, proteins, insulin, vaccine, nanoparticles, and herb extracts. The objective of this study is...

  • Feature Paper
  • Communication
  • Open Access
10 Citations
4,642 Views
6 Pages

Application of Confocal Raman Microscopy for the Analysis of the Distribution of Wood Preservative Coatings

  • Toru Kanbayashi,
  • Atsuko Ishikawa,
  • Masahiro Matsunaga,
  • Masahiko Kobayashi and
  • Yutaka Kataoka

27 September 2019

The distribution of wood preservative coatings in wood surface layer was assessed at the cellular level using confocal Raman microscopy. Raman images were created based on the fingerprint Raman bands of the different wood polymers and coating compone...

  • Article
  • Open Access
6 Citations
6,162 Views
11 Pages

14 September 2019

OTTER (opto-thermal transient emission radiometry) is an infrared remote sensing technology that has been extensively used in skin measurements. It is non-contact, non-invasive, and has a unique depth profiling capability. By selecting different dete...

  • Article
  • Open Access
273 Views
13 Pages

Eutectogels as Delivery Media for Therapeutic Metal Complexes: What Are the Benefits?

  • Varvara O. Veselova,
  • Svetlana V. Revtovich,
  • Vitalia V. Kulikova,
  • Arina D. Filippova,
  • Kseniya A. Koshenskova,
  • Nikolay N. Efimov,
  • Irina A. Lutsenko and
  • Marina A. Uvarova

11 January 2026

Drugs and drug candidate compounds commonly suffer from poor solubility and permeability. One promising strategy to mediate these drawbacks is use of novel solvents, such as deep eutectic compositions. The present research aims to determine the appli...

  • Article
  • Open Access
2 Citations
2,058 Views
22 Pages

10 April 2024

The study of porous liquids (PLs) using molecular dynamics (MD) simulation is one of the most interesting and attractive research topics. The possibility of creating permanent porosity in a solvent and increasing its adsorption capacity is very pract...

  • Feature Paper
  • Article
  • Open Access
22 Citations
6,174 Views
14 Pages

25 December 2018

We hypothesize that plasma treatments that increase the adhesion and penetration of transparent water, and solvent-borne polyurethane coatings into black spruce wood will improve the performance of coated wood exposed to accelerated weathering. We te...

  • Article
  • Open Access
13 Citations
3,158 Views
22 Pages

Systemic disposition of dermally applied chemicals is often formulation-dependent. Rapid evaporation of the vehicle can result in crystallization of active compounds, limiting their degree of skin penetration. In addition, the choice of vehicle can a...

  • Article
  • Open Access
4 Citations
4,540 Views
19 Pages

Alternatives to Conventional Topical Dosage Forms for Targeted Skin Penetration of Diclofenac Sodium

  • Benjamin Gavinet,
  • Séverine Sigurani,
  • Christine Garcia and
  • Alicia Roso

Skin penetration of an active pharmaceutical ingredient is key to developing topical drugs. This penetration can be adjusted for greater efficacy and/or safety through the selection of dosage form. Two emerging dosage forms, cream–gel and gel-i...

  • Article
  • Open Access
5 Citations
3,593 Views
16 Pages

29 May 2018

Adequate maintenance and taking active preventive measures can effectively prevent the early disease of asphalt pavements before significant damage occurs. By developing a light screening preventive maintenance agent (LS pre-maintenance agent) for st...

  • Article
  • Open Access
20 Citations
3,380 Views
9 Pages

29 August 2021

An organic solvent sensor of polymer-dispersed liquid crystals (PDLCs) film is fabricated by a combination of tri-functional monomers and LCs. When the patterned PDLC film comes into contact with the organic solvent, the organic solvent will penetrat...

  • Article
  • Open Access
14 Citations
2,049 Views
12 Pages

6 January 2022

High-quality cotton stalk fibers that are both fine and have a high breakage strength are extracted via limited alkali penetration in the glycerol solvent and simultaneous accelerated temperature rise by means of microwave-assisted heating. Alkali is...

  • Article
  • Open Access
2 Citations
1,109 Views
16 Pages

3 April 2025

The behavior of a single homopolymer chain in an explicit solvent in a wide range of poor and good solvents was investigated. For this purpose, a two-dimensional coarse-grained model based on a triangular lattice was used. Simulations were carried ou...

  • Article
  • Open Access
3 Citations
7,265 Views
12 Pages

On the Nature of the Transition State Characterizing Gated Molecular Encapsulations

  • Xiaoyong Lu,
  • Bao-Yu Wang,
  • Shigui Chen and
  • Jovica D. Badjić

11 September 2014

Gated molecular encapsulations, with baskets of type 1, are postulated to occur by the mechanism in which solvent molecule penetrates the inner space of 1, through one of its apertures, while the residing guest simultaneously departs the cavity. In t...

  • Article
  • Open Access
9 Citations
4,774 Views
13 Pages

The Applicability of a Drop Penetration Method to Measure Contact Angles on TiO2 and ZnO Nanoparticles

  • Sabrina M. Garner,
  • Edgar A. O’Rear,
  • Sharukh Soli Khajotia and
  • Fernando Luis Esteban Florez

In this study, six solvents (water, diiodomethane, bromonaphthalene, formamide, ethanol and ethylene glycol) were examined for three nanoparticle substrates, zinc oxide and titanium dioxide (21 nm and 100 nm), with the goal of assessing the suitabili...

  • Article
  • Open Access
7 Citations
3,280 Views
12 Pages

Dependence of the Optical Constant Parameters of p-Toluene Sulfonic Acid-Doped Polyaniline and Its Composites on Dispersion Solvents

  • Fahad Usman,
  • John Ojur Dennis,
  • Fabrice Meriaudeau,
  • Abdelaziz Yousif Ahmed,
  • Khe Cheng Seong,
  • Yap Wing Fen,
  • Amir Reza Sadrolhosseini,
  • Bashir Abubakar Abdulkadir,
  • Ridwan Tobi Ayinla and
  • Abdelmoneim Sulieman
  • + 3 authors

25 September 2020

The optical constants of Para-Toluene sulfonic acid-doped polyaniline (PANI), PANIchitosan composites, PANI-reduced graphene-oxide composites and a ternary composite comprising of PANI, chitosan and reduced graphene-oxide dispersed in diluted p-tolue...

  • Article
  • Open Access
7 Citations
2,203 Views
11 Pages

Ultra-Dispersed Powders Produced by High-Temperature Shear-Induced Grinding of Worn-Out Tire and Products of Their Interaction with Hot Bitumen

  • Vadim Nikol’skii,
  • Tatiana Dudareva,
  • Irina Krasotkina,
  • Irina Gordeeva,
  • Alexandre A. Vetcher and
  • Alexander Botin

1 September 2022

Structural features of crumb rubber (CR) particles obtained by grinding on rollers and ultra-disperse powder elastomeric modifiers (PEM) obtained by high-temperature shear-induced grinding (HTSG) of CR or co-grinding with butadiene styrene thermoplas...

  • Article
  • Open Access
2 Citations
3,251 Views
12 Pages

N,N-diethyl-3-toluamide (DEET) is one of the most widely used insect repellents in the world. It was reported that a solution containing 6–30% cyclodextrin (CD) as a solvent instead of ethanol (EtOH) provided an enhancement of the repellent act...

  • Review
  • Open Access
333 Citations
47,507 Views
19 Pages

Advances in Lipid Extraction Methods—A Review

  • Ramesh Kumar Saini,
  • Parchuri Prasad,
  • Xiaomin Shang and
  • Young-Soo Keum

20 December 2021

Extraction of lipids from biological tissues is a crucial step in lipid analysis. The selection of appropriate solvent is the most critical factor in the efficient extraction of lipids. A mixture of polar (to disrupt the protein-lipid complexes) and...

  • Article
  • Open Access
9 Citations
3,014 Views
19 Pages

22 March 2021

Experiments on swelling and solute transport in polymeric systems clearly indicate that the classical parabolic models fail to predict typical non-Fickian features of sorption kinetics. The formulation of moving-boundary transport models for solvent...

  • Article
  • Open Access
14 Citations
4,752 Views
14 Pages

Two-Dimensional MFI Zeolite Nanosheets Exfoliated by Surfactant Assisted Solution Process

  • Aafaq ur Rehman,
  • Devipriyanka Arepalli,
  • Syed Fakhar Alam,
  • Min-Zy Kim,
  • Jungkyu Choi and
  • Churl Hee Cho

7 September 2021

Two-dimensional (2D) zeolite nanosheets are important for the synthesis of high flux zeolite membranes due to their lateral size in a preferred orientation. A way to obtain 2D zeolite nanosheets is to exfoliate interlocked structures generated during...

  • Article
  • Open Access
5 Citations
1,922 Views
11 Pages

Compression Relaxation of Multi-Structure Polymer Composites in Penetrating Liquid Medium

  • Alexander Kondratov,
  • Valery Konyukhov,
  • Stanislav Yamilinets,
  • Ekaterina Marchenko and
  • Gulsharat Baigonakova

28 November 2022

Multi-structural polymer composites are widely used in the mechanical engineering, automotive, aviation and oil refining industries, as well as in the printing industry as a shock-absorbing deckle on the offset cylinders of printing machines. During...

  • Review
  • Open Access
97 Citations
17,598 Views
25 Pages

16 May 2023

Pressurized liquid extraction (PLE) is considered an advanced extraction technique developed in the mid-1990s with the aim of saving time and reducing solvent with respect to traditional extraction processes. It is commonly used with solid and semi-s...

  • Article
  • Open Access
4 Citations
3,569 Views
13 Pages

Counterbalance of Stability and Activity Observed for Thermostable Transaminase from Thermobaculum terrenum in the Presence of Organic Solvents

  • Ekaterina Yu. Bezsudnova,
  • Alena Yu. Nikolaeva,
  • Sergey Y. Kleymenov,
  • Tatiana E. Petrova,
  • Sofia A. Zavialova,
  • Kristina V. Tugaeva,
  • Nikolai N. Sluchanko and
  • Vladimir O. Popov

6 September 2020

Pyridoxal-5’-phosphate-dependent transaminases catalyze stereoselective amination of organic compounds and are highly important for industrial applications. Catalysis by transaminases often requires organic solvents to increase the solubility o...

  • Article
  • Open Access
3 Citations
2,571 Views
21 Pages

Unlocking the Stratum Corneum Barrier to Skin Penetration for the Transdermal Delivery of Cyclovirobuxine D

  • Yun-Hao Ren,
  • Feng-Yuan Song,
  • Jing-Yu Zhao,
  • Bing-Wen Liang and
  • Li-Hua Peng

Background/Objectives: Cyclovirobuxine D, a natural compound derived from the medicinal plant Buxus sinica, demonstrates a diverse array of therapeutic benefits, encompassing anti-arrhythmic properties, blood pressure regulation, neuronal protection,...

  • Review
  • Open Access
15 Citations
5,346 Views
17 Pages

An Insight into Enamel Resin Infiltrants with Experimental Compositions

  • Claudia Mazzitelli,
  • Uros Josic,
  • Tatjana Maravic,
  • Edoardo Mancuso,
  • Cecilia Goracci,
  • Milena Cadenaro,
  • Annalisa Mazzoni and
  • Lorenzo Breschi

19 December 2022

Resin infiltration is a conservative treatment of initial enamel carious lesions. Only one infiltrant material is available on the market (Icon, DMG), and research is now investigating new chemical compositions so as to further exploit the benefits o...

  • Article
  • Open Access
1,254 Views
21 Pages

Nanovesicles and Human Skin Interaction: A Comparative Ex-Vivo Study

  • Elisabetta Esposito,
  • Valentyn Dzyhovski,
  • Federico Santamaria,
  • Catia Contado,
  • Cinzia Brenna,
  • Luca Maria Neri,
  • Paola Secchiero,
  • Francesco Spinozzi,
  • Alessia Pepe and
  • Manuela Malatesta
  • + 5 authors

16 June 2025

The topical administration of drugs on the skin by nanovesicular systems can represent a tool to treat skin pathologies. The study of nanovesicle biodistribution after skin administration is crucial to understanding their transdermal potential. A for...

  • Article
  • Open Access
4 Citations
6,154 Views
7 Pages

Parallel-plate capacitors were fabricated using a printed multi-layer structure in order to determine the effects of particle size and solvent on the capacitance. The conductive-dielectric-conductive layers were sequentially spun using commercial ink...

  • Article
  • Open Access
2,824 Views
22 Pages

Nonionic Fast-Penetration System for Diffusion-Driven Degradation of Liquid Plugs

  • Yuexin Tian,
  • Yintao Liu,
  • Haifeng Dong,
  • Xiangjun Liu and
  • Jinjun Huang

25 June 2025

Degradable liquid gel plugs are increasingly required for zonal isolation in high-temperature reservoirs, yet their practical deployment is limited by slow internal degradation and insufficient structural failure under diffusive conditions. In this s...

  • Article
  • Open Access
1 Citations
2,105 Views
18 Pages

Molecular Dynamics of Lysine Dendrigrafts in Methanol–Water Mixtures

  • Emil I. Fatullaev,
  • Oleg V. Shavykin and
  • Igor M. Neelov

4 February 2023

The molecular dynamics method was used to study the structure and properties of dendrigrafts of the first and second generations in methanol–water mixtures with various volume fractions of methanol. At a small volume fraction of methanol, the s...

  • Article
  • Open Access
18 Citations
7,751 Views
20 Pages

Assessing the Solubility of Baricitinib and Drug Uptake in Different Tissues Using Absorption and Fluorescence Spectroscopies

  • Roya Mohammadi-Meyabadi,
  • Negar Beirampour,
  • Núria Garrós,
  • Helen Lissette Alvarado,
  • David Limón,
  • Marcelle Silva-Abreu,
  • Ana Cristina Calpena and
  • Mireia Mallandrich

The low water solubility of baricitinib (BCT) limits the development of new formulations for the topical delivery of the drug. The aims of this study were to assess the solubility of BCT in different solvents, including Transcutol, a biocompatible pe...

  • Article
  • Open Access
9 Citations
4,092 Views
14 Pages

Lanolin-Based Synthetic Membranes for Transdermal Permeation and Penetration Drug Delivery Assays

  • Cristina Alonso,
  • Ilaria Collini,
  • Meritxell Martí,
  • Clara Barba and
  • Luisa Coderch

Due to the high similarity in composition and structure between lanolin and human SC lipids, we will work with two models from wool wax. Two types of lanolin were evaluated: one extracted with water and surfactants (WEL) and the other extracted with...

  • Article
  • Open Access
2 Citations
2,605 Views
24 Pages

21 March 2023

Nanolimes have been commercially available for over a decade as a remineralization agent for natural stone to combat deterioration. While they have been applied successfully and studied extensively, their penetration abilities in different materials...

  • Article
  • Open Access
22 Citations
7,437 Views
16 Pages

31 December 2014

An effective vacuum assisted extraction (VAE) technique was proposed for the first time and applied to extract bioactive components from Andrographis paniculata. The process was carefully optimized by response surface methodology (RSM). Under the opt...

  • Review
  • Open Access
2 Citations
8,976 Views
35 Pages

Aroma Compounds of Carrier Oils

  • Tyler Marshall,
  • Noura S. Dosoky,
  • Prabodh Satyal and
  • William N. Setzer

8 December 2023

Carrier oils are used with essential oils to dilute and enhance skin penetration. They are composed of fatty acids, triglycerides, monoterpenes, and sesquiterpenes and are added to reduce potency and odor. Carrier oils have pharmaceutical application...

  • Article
  • Open Access
2 Citations
1,875 Views
17 Pages

Assessing the Use of Supercritical Carbon Dioxide as a Carrier for Alkoxysilanes to Consolidate Degraded PUR Ester Foams: An Alternative to Traditional Methods

  • Inês Soares,
  • Carolina Viana,
  • Angelica Bartoletti,
  • Susana França de Sá,
  • Anita Quye,
  • Yvonne Shashoua,
  • Teresa Casimiro and
  • Joana Lia Ferreira

22 May 2024

Degradation of ester-based polyurethane (PUR) foams results in extensive fragmentation, stickiness, and brittleness both at surfaces and in the bulk. Current methods to conserve museum objects comprising PUR foams include consolidation with solvent-b...

  • Article
  • Open Access
2 Citations
2,323 Views
15 Pages

13 July 2023

The molecular transport of a series of industrial solvent mixtures into O-rings of Viton fluoropolymers was studied. Sorption, diffusion, and permeation of the individual liquids toluene, cyclohexane, and methanol, and their binary and ternary mixtur...

  • Article
  • Open Access
7 Citations
3,876 Views
15 Pages

1 September 2017

This research work addresses the issue of developing light composite materials with increased ability for impact energy absorption. Novel, hybrid plain woven glass fibre fabric-epoxy laminates with multi-walled carbon nanotube (MWNT) interlayers were...

  • Feature Paper
  • Article
  • Open Access
10 Citations
3,646 Views
11 Pages

23 June 2022

Near-infrared (NIR) light-triggered photoredox catalysis is highly desirable because NIR light occupies almost 50% of solar energy and possesses excellent penetrating power in various media. Herein we utilize a metal-free boron dipyrromethene (BODIPY...

  • Article
  • Open Access
1 Citations
1,894 Views
13 Pages

Synthesis Optimization of BaGdF5:x%Tb3+ Nanophosphors for Tunable Particle Size

  • Vladimir Polyakov,
  • Zaira Gadzhimagomedova,
  • Daria Kirsanova and
  • Alexander Soldatov

1 December 2022

X-ray photodynamic therapy (XPDT) is aimed at the treatment of deep-located malignant tumors thanks to the high penetration depth of X-rays. In XPDT therapy, it is necessary to use materials that effectively absorb X-rays and convert them into visibl...

  • Article
  • Open Access
16 Citations
4,923 Views
19 Pages

One of the major challenges in membrane manufacturing today is to reduce the environmental footprint by promoting biobased raw materials and limiting the use of toxic solvents. In this context, environmentally friendly chitosan/kaolin composite membr...

  • Article
  • Open Access
12 Citations
4,084 Views
19 Pages

28 February 2020

Considering that consolidant products are commonly used in the cultural heritage field and the titanium oxide nanoparticles (TiO2) have been used to develop photocatalyst films to induce self-cleaning property, the scientific research on consolidants...

  • Article
  • Open Access
19 Citations
4,175 Views
19 Pages

Analysis of a Wide Range of Commercial Exterior Wood Coatings

  • Michael J. Gibbons,
  • Saeid Nikafshar,
  • Tina Saravi,
  • Katie Ohno,
  • Sanjeev Chandra and
  • Mojgan Nejad

22 October 2020

This study was focused on measuring the properties of twenty-three commercially available coatings formulated for exterior wood applications. The coatings were characterized by measuring their surface tension, solid content, viscosity, pH, and glass...

  • Article
  • Open Access
9 Citations
4,001 Views
13 Pages

30 April 2024

Despite the excellent oxygen barrier and biodegradability of polyvinyl alcohol (PVA), its poor physical properties owing to its inherent hydrophilicity limit its application. In this paper, we report a novel surface modification technique for PVA fil...

  • Article
  • Open Access
3 Citations
4,108 Views
12 Pages

Selective Oxidation of Citronellol over Titanosilicate Catalysts

  • Daifallah Aldhayan,
  • Květa Kalíková,
  • Mohammed Rafi Shaik,
  • Mohammed Rafiq H. Siddiqui and
  • Jan Přech

5 November 2020

Citronellol is one of the most widely used fragrances for bouquetting purposes and it is a starting material for synthesis of several other terpenoids. Nevertheless, few data have been reported on citronellol selective oxidation. Accordingly, we repo...

  • Article
  • Open Access
575 Views
23 Pages

Comparative Analysis of Impregnation Methods for Polyimide-Based Prepregs: Insights from Industrial Perspective

  • Biljana Kostadinoska,
  • Blagoja Samakoski,
  • Samoil Samak,
  • Dijana Cvetkoska and
  • Anka Trajkovska Petkoska

1 December 2025

This study presents a comparative analysis of two industrially relevant technologies for manufacturing of prepreg composite materials based on polyimide (PI) resin: hot-melt and solvent-based technology. More specifically, the study focuses on evalua...

  • Review
  • Open Access
75 Citations
14,580 Views
19 Pages

Film-Forming Systems for Dermal Drug Delivery

  • Larissa Carine Pünnel and
  • Dominique Jasmin Lunter

Film-forming formulations represent a novel form of sustained release dermatic products. They are applied to the skin as a liquid or semi-solid preparation. By evaporation of the volatile solvent on the skin, the polymer contained in the formulation...

  • Article
  • Open Access
7 Citations
2,270 Views
26 Pages

Effect of Hydroxyl-Containing Fragments on the Structure and Properties of Membrane-Forming Polyamide-Imides

  • Svetlana V. Kononova,
  • Galina K. Lebedeva,
  • Galina N. Gubanova,
  • Elena V. Kruchinina,
  • Elena N. Vlasova,
  • Nadezhda V. Afanas’eva,
  • Elena N. Popova,
  • Anatoly Ya. Volkov,
  • Elena N. Bykova and
  • Natalya V. Zakharova

The structural features and thermophysical and transport properties of dense nonporous membranes of the casting type from (co)polyamide-imides synthesized by the polycondensation of the diacid chloride of 2-(4-carboxyphenyl)-1,3-dioxoisoindoline-5-ca...

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