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40 Results Found

  • Article
  • Open Access
7 Citations
4,021 Views
27 Pages

12 April 2024

The aim of the study was to compare the antioxidant activity and polyphenol content in extracts prepared from freeze-dried leaves of three apple cultivars: Ligol, Gala, and Gloster, using different solvents and extraction methods. The content of tota...

  • Article
  • Open Access
5 Citations
3,705 Views
13 Pages

27 July 2020

In this work, we developed an extraction technique that can handle simple as well as complex matrixed liquid (aqueous) samples. In the standard liquid–liquid extraction, it is quite challenging to deal with complex liquid samples as they may co...

  • Article
  • Open Access
4 Citations
5,109 Views
21 Pages

Integrated Metabolomics and Transcriptomics Using an Optimised Dual Extraction Process to Study Human Brain Cancer Cells and Tissues

  • Alison Woodward,
  • Alina Pandele,
  • Salah Abdelrazig,
  • Catherine A. Ortori,
  • Iqbal Khan,
  • Marcos Castellanos Uribe,
  • Sean May,
  • David A. Barrett,
  • Richard G. Grundy and
  • Dong-Hyun Kim
  • + 1 author

14 April 2021

The integration of untargeted metabolomics and transcriptomics from the same population of cells or tissue enhances the confidence in the identified metabolic pathways and understanding of the enzyme–metabolite relationship. Here, we optimised a simu...

  • Article
  • Open Access
10 Citations
5,700 Views
10 Pages

Isolation and Maximisation of Extraction of Mangiferin from the Root of Salacia chinensis L.

  • Thanh V. Ngo,
  • Christopher J. Scarlett,
  • Michael C. Bowyer and
  • Quan V. Vuong

Mangiferin has been reported to exhibit anti-viral, anti-cancer, anti-diabetic, immunomodulatory and hepatoprotective properties. This study aimed to develop an HPLC method to isolate mangiferin from Salacia chinensis L. root; investigate the impact...

  • Article
  • Open Access
152 Citations
13,903 Views
17 Pages

Comparison of Cell Disruption Methods for Improving Lipid Extraction from Thraustochytrid Strains

  • Avinesh R. Byreddy,
  • Adarsha Gupta,
  • Colin J. Barrow and
  • Munish Puri

11 August 2015

Lipid extraction is an integral part of biodiesel production, as it facilitates the release of fatty acids from algal cells. To utilise thraustochytrids as a potential source for lipid production. We evaluated the extraction efficiency of various sol...

  • Article
  • Open Access
1,006 Citations
59,715 Views
14 Pages

15 June 2009

Theeffects of four extracting solvents [absolute ethanol, absolute methanol, aqueous ethanol (ethanol: water, 80:20 v/v) and aqueous methanol (methanol: water, 80:20 v/v)] and two extraction techniques (shaking and reflux) on the antioxidant activity...

  • Article
  • Open Access
12 Citations
5,205 Views
15 Pages

12 April 2023

The effect of the extraction conditions on the DPPH radical scavenging activity and isolation of bioactive compounds from the maca (Lepidium meyenii) root was investigated. Different extraction techniques (maceration, maceration with shaking, ultraso...

  • Article
  • Open Access
4 Citations
3,327 Views
16 Pages

Simultaneous Determination of Multiresidues of Pesticides and Veterinary Drugs in Agricultural Soil Using QuEChERS and UHPLC–MS/MS

  • Michele C. Vicari,
  • Janice F. Facco,
  • Sandra C. Peixoto,
  • Gabriel S. de Carvalho,
  • Luana Floriano,
  • Osmar D. Prestes,
  • Martha B. Adaime and
  • Renato Zanella

Soil is one of the main destinations for pesticides and veterinary drugs used in agriculture and animal production. The negative consequences of the accumulation of these compounds in the environment make it important to monitor these compounds in th...

  • Article
  • Open Access
21 Citations
5,076 Views
13 Pages

26 December 2021

The lemon-scented tea tree (LSTT) is an Australian native herb and is a rich source of essential oil and phenolics. The ETHOS X extraction system is known as a commercial microwave-assisted extraction (MAE) system for extracting bioactive compounds f...

  • Article
  • Open Access
17 Citations
6,461 Views
15 Pages

Separation of Aluminum and Iron from Lanthanum—A Comparative Study of Solvent Extraction and Hydrolysis-Precipitation

  • Adam Balinski,
  • Norman Kelly,
  • Toni Helbig,
  • Christina Meskers and
  • Markus Andreas Reuter

20 June 2020

This study investigates the removal of aluminum and iron from rare earth element (REE) containing solutions by solvent extraction with saponified naphthenic acid and by hydrolysis-precipitation. The results emphasize both, the preferential applicatio...

  • Article
  • Open Access
15 Citations
4,202 Views
15 Pages

Advanced Oxidation Based Treatment of Soil Wash Water Contaminated with Sulfolane

  • Mariana Brandão,
  • Linlong Yu,
  • Carlos Garcia and
  • Gopal Achari

16 October 2019

This study investigates advanced oxidation processes (AOPs) as post-treatment techniques to degrade sulfolane in soil washing water. Soil washing experiments were conducted with different soil/water ratios, shaking times, and number of extraction cyc...

  • Article
  • Open Access
11 Citations
7,771 Views
11 Pages

22 September 2017

The partition coefficients, Kmim, of N-methylimidazole (mim) in two-component systems composed of ionic liquid (IL) and a series of organic solvents immiscible with ILs (butyl acetate, ethyl acetate, tert-butyl methyl ether, diethyl ether and cyclohe...

  • Article
  • Open Access
34 Citations
10,673 Views
19 Pages

8 December 2021

The aromatic herb lemon myrtle is a good source of polyphenols, with high antioxidant and antimicrobial capacity. In this study, the green extraction technique microwave-assisted extraction (MAE) was applied and the extraction parameters were optimiz...

  • Review
  • Open Access
2 Citations
1,943 Views
17 Pages

Exploring the Influence of Extraction Methods, Solvents, and Temperature on Total Phenolic Recovery and Antioxidant Capacity in Olive Leaf Extracts: A Systematic Review with Quantitative Synthesis

  • María Castillo-Correa,
  • Cristina Montalbán-Hernández,
  • María D. Navarro-Hortal,
  • Diego Peña-Guzmán,
  • Alberto Badillo-Carrasco,
  • Alfonso Varela-López,
  • Daniel Hinojosa-Nogueira and
  • Jose M. Romero Márquez

3 September 2025

Background: Olive leaves are a rich source of bioactive phenolic compounds, but extraction yields vary depending on methodological choices. The aim was to identify optimal parameters for maximizing recovery and preserving antioxidant activity. Method...

  • Feature Paper
  • Article
  • Open Access
46 Citations
9,085 Views
11 Pages

17 April 2020

The aim of this study was to find the best design that is suitable for optimizing the recovery of the representatives of the 2nd, 3rd and 4th generation of fluoroquinolones. The following designs were applied: Central Composite Design, Box–Behn...

  • Article
  • Open Access
14 Citations
5,108 Views
19 Pages

16 December 2022

The aim of this study was to verify various extraction methods: shaking water bath extraction (SWA), ultrasound-assisted extraction (UAE) and microwave assisted extraction (MAE), and their parameters to optimize the extraction yield as well as maximi...

  • Article
  • Open Access
8 Citations
1,417 Views
14 Pages

3 February 2000

Methods for spectrophotometric determination of fenbendazole and ornidazde are described. The methods are based on the formation and extraction of the ion-pair complex formed between bromothymol blue and either fenbendazole (FBZ) or ornidazole (ORN)....

  • Article
  • Open Access
16 Citations
9,410 Views
11 Pages

29 September 2020

Elaeocarpus serratus L. leaves contain significant polyphenols, flavonoids, and myricitrin with medicinal property, which are byproducts after harvest and can be recovered for potential food applications. In this study, the effective extraction metho...

  • Article
  • Open Access
4 Citations
3,334 Views
14 Pages

Influence of Geographical Location of Spirulina (Arthrospira platensis) on the Recovery of Bioactive Compounds Assisted by Pulsed Electric Fields

  • Francesc Ramon-Mascarell,
  • Francisco J. Martí-Quijal,
  • Juan Manuel Castagnini,
  • Yuthana Phimolsiripol,
  • Warintorn Ruksiriwanich,
  • Muhammad Shahid Riaz Rajoka,
  • Hafiza Mahreen Mehwish and
  • Francisco J. Barba

13 September 2022

Spirulina (Arthrospira platensis) has been consumed by humans since ancient times. It is rich in high added-value compounds such as chlorophylls, carotenoids and polyphenols. Pulsed electric fields (PEF) is an innovative non-thermal technique that im...

  • Article
  • Open Access
9 Citations
6,107 Views
14 Pages

Production of Polyhydroxyalkanoates by Bacillus megaterium: Prospecting on Rice Hull and Residual Glycerol Potential

  • Vanessa Kristine de Oliveira Schmidt,
  • Evelise Fonseca dos Santos,
  • Débora de Oliveira,
  • Marco Antônio Záchia Ayub,
  • Karina Cesca,
  • Paulo Roberto Dall Cortivo,
  • Cristiano José de Andrade and
  • Lilian Raquel Hickert

16 December 2022

The production of polyhydroxyalkanoates (PHAs) by Bacillus megaterium using industrial residues, crude glycerol from biodiesel synthesis and rice hull hydrolysate (RHH), as low-cost carbon sources was investigated. The experiments were conducted by s...

  • Article
  • Open Access
9 Citations
8,885 Views
11 Pages

Polychlorinated biphenyls (PCBs) have been found in soil, which has typically been the result of industrial pollution in the past two decades. Although they are banned, PCBs can still be found in soils and other environmental media. For this reason,...

  • Article
  • Open Access
21 Citations
4,910 Views
18 Pages

Enhancing Efficiency of Enzymatic-Assisted Extraction Method for Evaluating Bioactive Compound Analysis in Mulberry: An Optimization Approach

  • Ainara Tizón Alba,
  • María José Aliaño-González,
  • Miguel Palma,
  • Gerardo Fernández Barbero and
  • Ceferino Carrera

3 October 2023

The present investigation endeavors to optimize a method based on enzyme-assisted extraction for the efficient retrieval of bioactive compounds from mulberry, leveraging its notable health-promoting properties. A combined approach of Plackett–B...

  • Feature Paper
  • Article
  • Open Access
43 Citations
5,759 Views
17 Pages

Ultrasound Extraction Mediated Recovery of Nutrients and Antioxidant Bioactive Compounds from Phaeodactylum tricornutum Microalgae

  • Fadila Al Khawli,
  • Francisco J. Martí-Quijal,
  • Noelia Pallarés,
  • Francisco J. Barba and
  • Emilia Ferrer

14 February 2021

In recent years, a growing interest has been shown in the use of microalgae due to their interesting nutritional and bioactive profiles. Green innovative processing technologies such as ultrasound-assisted extraction (UAE) avoid the use of toxic solv...

  • Article
  • Open Access
21 Citations
5,649 Views
14 Pages

Acetylcholinesterase Inhibitors among Zingiber officinale Terpenes—Extraction Conditions and Thin Layer Chromatography-Based Bioautography Studies

  • Lidia Czernicka,
  • Agnieszka Ludwiczuk,
  • Edward Rój,
  • Zbigniew Marzec,
  • Agata Jarzab and
  • Wirginia Kukula-Koch

Although numerous studies have been conducted on ginger extracts and fractions, the data on the pharmacological activity of single constituents of Zingiber officinale are still insufficient. To assess the antidementia properties of the plant, a thin...

  • Article
  • Open Access
6 Citations
2,235 Views
12 Pages

Evaluation of Anti-Infection and Anti-Diabetic Activities in Methanolic and n-Hexane Plant Extracts of Indigenously Cultivated Chenopodium album

  • Ijaz Hussain,
  • Muhammad Ramzan Saeed Ashraf Janjua,
  • Atta Ul Haq,
  • Sadaf Ul Hassan,
  • Faisal Miqad K. Albaqami,
  • Meshari A. Alsuwat,
  • Barakat M. Alrashdi,
  • Sarah Alzwain and
  • Syed Ali Raza Naqvi

21 June 2024

The Asian region of earth has a rich agriculture system that provides extensive opportunities to boost pharmaceutical and nutritional research to address the use of food crops for health benefits and potential clinical applications. The traditionally...

  • Article
  • Open Access
2 Citations
1,200 Views
17 Pages

Green Extraction and Targeted LC-MS Analysis of Biopesticides in Honey Using Natural Deep Eutectic Solvents

  • Theaveraj Ravi,
  • Alba Reyes-Ávila,
  • Laura Carbonell-Rozas,
  • Asiah Nusaibah Masri,
  • Antonia Garrido Frenich and
  • Roberto Romero-González

8 October 2025

Natural Deep Eutectic Solvents (NADES) were synthesized from food-grade components and evaluated as green extractants for the simultaneous recovery and liquid chromatography coupled to quadrupole-Orbitrap mass spectrometry (LC–Q-Orbitrap-MS) an...

  • Feature Paper
  • Article
  • Open Access
59 Citations
7,602 Views
16 Pages

Extraction of Antioxidant Compounds and Pigments from Spirulina (Arthrospira platensis) Assisted by Pulsed Electric Fields and the Binary Mixture of Organic Solvents and Water

  • Francisco J. Martí-Quijal,
  • Francesc Ramon-Mascarell,
  • Noelia Pallarés,
  • Emilia Ferrer,
  • Houda Berrada,
  • Yuthana Phimolsiripol and
  • Francisco J. Barba

19 August 2021

The application of pulsed electric fields (PEF) is an innovative extraction technology promoting cell membrane electroporation, thus allowing for an efficient recovery, from an energy point of view, of antioxidant compounds (chlorophylls, carotenoids...

  • Feature Paper
  • Article
  • Open Access
30 Citations
5,605 Views
14 Pages

17 December 2020

Potato peels (PPs) are generally considered as agriculture waste. The United States alone generates over one million tons of PPs a year. However, PPs contain valuable phenolic compounds with antioxidant activities. In this study, we evaluated the eff...

  • Article
  • Open Access
3 Citations
2,972 Views
14 Pages

Ultrasound-Assisted Extraction of Phenolic Compounds and Flavonoids from Banana Inflorescence and Characterization of Its Fibrous Residue

  • Fábio Dias Bertoco Júnior,
  • Érica Marusa Pergo Coelho,
  • Mirian Cristina Feiten and
  • Beatriz Cervejeira Bolanho Barros

The banana inflorescence (BI) is a rich source of antioxidants and dietary fiber, making it a valuable by-product of banana harvesting. This study aimed to maximize the ultrasound-assisted extraction (UAE) of antioxidant compounds from BI and analyze...

  • Article
  • Open Access
6 Citations
1,835 Views
13 Pages

30 October 2024

The bioactive compounds in burdock (Arctium lappa L.) roots, including chlorogenic acid (CGA) and cynarin, are valuable for use in nutraceutical foods. The ultrasound-assisted extraction of bioactive substances from dried burdock root powder (DBR) wa...

  • Abstract
  • Open Access
664 Views
2 Pages

Leaching Kinetics of Ironmaking Blast Furnace Slag as a Source of Calcium for CO2 Sequestration

  • Makhitha Masipa,
  • Itumeleng Kohitlhetse,
  • Hilary Rutto,
  • Kentse Motsetse and
  • Malibongwe S. Manono

An ironmaking blast furnace slag was prepared and dissolved in lixiviant solutions of known concentrations for the leaching of calcium. A portable laboratory orbital shaking incubator was used for the leaching experiments. In addition, XRF and AAS we...

  • Article
  • Open Access
2,116 Views
16 Pages

Perilla Seed Meal Extract Enriched with Rosmarinic Acid and Luteolin: Natural Active Pharmaceutical Ingredients (NAPIs) for Osteoprotective Effects

  • Thanawat Pattananandecha,
  • Sutasinee Apichai,
  • Treethip Sukkho,
  • Jetsada Ruangsuriya,
  • Fumihiko Ogata,
  • Naohito Kawasaki and
  • Chalermpong Saenjum

Perilla seed meal (PSM) is a waste biomass of perilla seed extraction that retains flavonoid and phenolic compounds. In this study, we aimed to investigate the potential of PSM extracts (PSMEs) from Perilla frutescens (L.) Britton as a sustainable so...

  • Article
  • Open Access
4 Citations
2,644 Views
14 Pages

Optimization of Extraction Conditions and Cytotoxic Activity of Rapanone in Comparison to Its Homologue, Embelin

  • Dagmara Wróbel-Biedrawa,
  • Agnieszka Galanty,
  • Paweł Zagrodzki and
  • Irma Podolak

16 November 2022

Rapanone is a plant-derived simple alkyl-dihydroxybenzoquinone structurally close to embelin, a well-known cytotoxic agent. The pharmacological characterization of rapanone is still incomplete, and to fill the data gap, a good source for its acquisit...

  • Article
  • Open Access
11 Citations
3,724 Views
10 Pages

22 March 2020

We developed, optimized and validated a fast analytical cycle using high throughput bar adsorptive microextraction and microliquid desorption (HT-BAμE-μLD) for the extraction and desorption of ketamine and norketamine in up to 100 urine samples...

  • Article
  • Open Access
35 Citations
4,056 Views
21 Pages

Synthesis of a New Chelating Iminophosphorane Derivative (Phosphazene) for U(VI) Recovery

  • Bahig M. Atia,
  • Ahmed K. Sakr,
  • Mohamed A. Gado,
  • Hassan S. El-Gendy,
  • Nagwa M. Abdelazeem,
  • Enass M. El-Sheikh,
  • Mohamed Y. Hanfi,
  • M. I. Sayyed,
  • Jamelah S. Al-Otaibi and
  • Mohamed F. Cheira

21 April 2022

A new synthetic chelating N–hydroxy–N–trioctyl iminophosphorane (HTIP) was prepared through the reaction of trioctylphosphine oxide (TOPO) with N–hydroxylamine hydrochloride in the presence of a Lewis acid (AlCl3). Specificati...

  • Article
  • Open Access
12 Citations
4,172 Views
16 Pages

Design of Experiments-Based Optimization of Flavonoids Extraction from Daphne genkwa Flower Buds and Flavonoids Contents at Different Blooming Stages

  • Min-Kyoung Kim,
  • Geonha Park,
  • Yura Ji,
  • Yun-Gyo Lee,
  • Minsik Choi,
  • Seung-Hyeon Go,
  • Miwon Son and
  • Young-Pyo Jang

29 March 2022

The flower buds of Daphne genkwa have been reported as a potent resource associated with anti-angiogenic, anti-tumor, anti-rheumatoid arthritis activities, as well as immunoregulation. This paper aimed to establish an optimal extraction method for fl...

  • Proceeding Paper
  • Open Access
1 Citations
3,158 Views
15 Pages

Investigating the Effect of Reaction Temperature on the Extraction of Calcium from Ironmaking Slag: A Kinetics Study

  • Itumeleng Kohitlhetse,
  • Kentse Thubakgale,
  • Peter Mendonidis and
  • Malibongwe Manono

Beneficiation of iron and steel slags have a great potential in mitigating high levels of anthropogenic carbon dioxide (CO2) gas emissions owing to their high contents of calcium and magnesium. Carbonation of calcium and magnesium leaching solutions...

  • Article
  • Open Access
4 Citations
1,760 Views
23 Pages

Extraction Optimization and Bioactivity of Polysaccharides from Ganoderma leucocontextum Spores

  • Siying Peng,
  • Yanghui Ou,
  • Yali Zhang,
  • Hongliang Yao and
  • Wen-Hua Chen

11 February 2025

Background: Oxidative stress is associated with the occurrence and progress of aging. Natural polysaccharides have attracted considerable attention in the field of antioxidants and anti-aging products due to their superior biological activity and low...

  • Article
  • Open Access
56 Citations
6,019 Views
17 Pages

Assessment of Pesticide Residue Content in Polish Agricultural Soils

  • Aleksandra Ukalska-Jaruga,
  • Bożena Smreczak and
  • Grzegorz Siebielec

29 January 2020

Pesticides belong to a group of xenobiotics harmful to humans and wildlife, whose fate and activity depends on their susceptibility to degradation. Therefore, the monitoring of their residue level in agricultural soils is very important because it pr...

  • Abstract
  • Open Access
2 Citations
1,878 Views
2 Pages

Determination of CBD in Ethanol Extracts Prepared from Hemp (Cannabis sativa L.) Cultivar Beniko Using Dynamic Maceration and Ultrasound Assisted Extraction

  • Milena Szalata,
  • Mariola Dreger,
  • Grażyna Mańkowska,
  • Małgorzata Górska-Paukszta,
  • Marcin Ożarowski and
  • Karolina Wielgus

Hemp (Cannabis sativa L.) has been known as a source of fibres, oil and medicines since ancient times (4000 B.C.). Currently, there is an increasing interest in fibrous hemp as a source of compounds with pharmacological activity. Cannabis is rich in...