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5,701 Results Found

  • Article
  • Open Access
3 Citations
2,100 Views
13 Pages

27 November 2023

Slow-releasing tablets combined with persulfate acting as an oxidant and ferrous iron acting as an activator were manufactured for in situ chemical oxidation. The trichloroethylene (TCE) removal efficiency according to the molar ratio of the oxidizer...

  • Article
  • Open Access
11 Citations
2,170 Views
13 Pages

Shock-Induced Energy Release Performances of PTFE/Al/Oxide

  • Ying Yuan,
  • Dongfang Shi,
  • Suo He,
  • Huanguo Guo,
  • Yuanfeng Zheng,
  • Yong Zhang and
  • Haifu Wang

22 April 2022

In recent years, polytetrafluoroethylene (PTFE)/aluminum (Al) energetic materials with high-energy density have attracted extensive attention and have broad application prospects, but the low-energy release efficiency restricts their application. In...

  • Article
  • Open Access
37 Citations
7,686 Views
17 Pages

Nitric Oxide Releasing Polymeric Coatings for the Prevention of Biofilm Formation

  • George Fleming,
  • Jenny Aveyard,
  • Joanne L. Fothergill,
  • Fiona McBride,
  • Rasmita Raval and
  • Raechelle A. D’Sa

11 November 2017

The ability of nitric oxide (NO)-releasing polymer coatings to prevent biofilm formation is described. NO-releasing coatings on (poly(ethylene terephthalate) (PET) and silicone elastomer (SE)) were fabricated using aminosilane precursors. Pristine PE...

  • Article
  • Open Access
5 Citations
2,146 Views
13 Pages

Controlling Shock-Induced Energy Release Characteristics of PTFE/Al by Adding Oxides

  • Ying Yuan,
  • Yiqiang Cai,
  • Dongfang Shi,
  • Pengwan Chen,
  • Rui Liu and
  • Haifu Wang

10 August 2022

Polytetrafluoroethylene (PTFE)/aluminum (Al)-based energetic material is a kind of energetic material with great application potential. In this research, the control of the shock-induced energy release characteristics of PTFE/Al-based energetic mater...

  • Article
  • Open Access
8 Citations
3,162 Views
15 Pages

7 December 2021

Elevated emissions of hydrogen chloride (HCl) from the combustion of biomass in utility boilers are a major issue because they can cause corrosion problems and deposit molten alkali chloride salts on boilers’ water tubes, resulting in further c...

  • Review
  • Open Access
30 Citations
5,552 Views
26 Pages

Nitric Oxide-Releasing Platforms for Treating Cardiovascular Disease

  • Mingyue He,
  • Deping Wang,
  • Yumei Xu,
  • Fangying Jiang,
  • Jian Zheng,
  • Yanlin Feng,
  • Jimin Cao and
  • Xin Zhou

Cardiovascular disease (CVD) is the first leading cause of death globally. Nitric oxide (NO) is an important signaling molecule that mediates diverse processes in the cardiovascular system, thereby providing a fundamental basis for NO-based therapy o...

  • Article
  • Open Access
5 Citations
3,095 Views
16 Pages

5 March 2024

In China, most of the high-sulfur iron ores have not been fully developed and utilized due to the lack of breakthrough progress in the research on the sulfur migration and the desulfurization mechanism during the roasting process. This study will foc...

  • Review
  • Open Access
148 Citations
13,226 Views
31 Pages

Nitric Oxide-Releasing Polymeric Materials for Antimicrobial Applications: A Review

  • Fan Rong,
  • Yizhang Tang,
  • Tengjiao Wang,
  • Tao Feng,
  • Jiang Song,
  • Peng Li and
  • Wei Huang

15 November 2019

Polymeric materials releasing nitric oxide have attracted significant attention for therapeutic use in recent years. As one of the gaseous signaling agents in eukaryotic cells, endogenously generated nitric oxide (NO) is also capable of regulating th...

  • Article
  • Open Access
8 Citations
2,409 Views
18 Pages

Simultaneous Release of Silver Ions and 10–Undecenoic Acid from Silver Iron–Oxide Nanoparticles Impregnated Membranes

  • Gheorghe Nechifor,
  • Alexandra Raluca Grosu,
  • Andreea Ferencz (Dinu),
  • Szidonia-Katalin Tanczos,
  • Alexandru Goran,
  • Vlad-Alexandru Grosu,
  • Simona Gabriela Bungău,
  • Florentina Mihaela Păncescu,
  • Paul Constantin Albu and
  • Aurelia Cristina Nechifor

The bio-medical benefits of silver ions and 10–undecenoic acid in various chemical-pharmaceutical preparations are indisputable, thus justifying numerous research studies on delayed and/or controlled release. This paper presents the effect of t...

  • Article
  • Open Access
19 Citations
7,643 Views
11 Pages

Polyvinyl chloride (PVC) is one of the most widely used polymers in medicine but has very poor biocompatibility when in contact with tissue or blood. To increase biocompatibility, controlled release of nitric oxide (NO) can be utilized to mitigate an...

  • Article
  • Open Access
7 Citations
7,290 Views
10 Pages

8 February 2018

Polyacrylate polymer (PA) was modified with graphene oxide (GO) and the obtained composites were applied as coatings for controlled-release coated urea (CRU). The physicochemical properties of the different PA/GO coatings were characterized in detail...

  • Feature Paper
  • Article
  • Open Access
10 Citations
5,562 Views
13 Pages

Comparative Study of Various Graphene Oxide Structures as Efficient Drug Release Systems for Ibuprofen

  • Panagiota Zygouri,
  • Konstantinos Spyrou,
  • Demetrios K. Papayannis,
  • Georgios Asimakopoulos,
  • Evangelia Dounousi,
  • Haralambos Stamatis,
  • Dimitrios Gournis and
  • Petra Rudolf

Ibuprofen is a non-steroidal, anti-inflammatory drug that is widely prescribed for its analgesic, antipyretic, and anti-inflammatory actions to treat pain, symptoms of rheumatoid arthritis and fever, but it is also known to cause stomach-related side...

  • Article
  • Open Access
22 Citations
3,365 Views
13 Pages

Fabrication and Evaluation of Graphene Oxide/Hydroxypropyl Cellulose/Chitosan Hybrid Aerogel for 5-Fluorouracil Release

  • Yanan Sang,
  • Pengpai Miao,
  • Tao Chen,
  • Yuan Zhao,
  • Linfeng Chen,
  • Yayang Tian,
  • Xiaobing Han and
  • Jie Gao

12 October 2022

The incorporation of graphene oxide (GO) into a polymeric drug carrier can not only enhance the loading efficiency but also reduce the initial burst and consequently improve the controllability of drug release. Firstly, 5-fluorouracil (5-Fu)-loaded h...

  • Article
  • Open Access
5 Citations
3,574 Views
17 Pages

Release of Bioactive Molecules from Graphene Oxide-Alginate Hybrid Hydrogels: Effect of Crosslinking Method

  • Lorenzo Francesco Madeo,
  • Manuela Curcio,
  • Francesca Iemma,
  • Fiore Pasquale Nicoletta,
  • Silke Hampel and
  • Giuseppe Cirillo

8 January 2023

To investigate the influence of crosslinking methods on the releasing performance of hybrid hydrogels, we synthesized two systems consisting of Graphene oxide (GO) as a functional element and alginate as polymer counterpart by means of ionic gelation...

  • Article
  • Open Access
11 Citations
3,188 Views
25 Pages

24 June 2023

Chitosan (CS) composite membranes were prepared using different biocompatible metal oxide nanoparticles (NPs): titanium dioxide (TiO2); iron oxide (Fe3O4); and aluminum oxide (Al2O3). For each nanoparticle, the CS-based composite membranes were prepa...

  • Article
  • Open Access
185 Views
13 Pages

Low-Temperature Oxidation Behavior and Non-Isothermal Heat Release of Heavy Oil During Oxygen-Reduced Air Injection

  • Wuchao Wang,
  • Defei Chen,
  • Zhaocai Pan,
  • Jianfeng He,
  • Jianxin Shen,
  • Min Liu,
  • Yanzhao Li,
  • Meili Lan and
  • Shuai Zhao

31 December 2025

Oxygen-reduced air injection technology has demonstrated considerable potential for developing heavy oil reservoirs. However, the low-temperature oxidation (LTO) behavior and non-isothermal heat release of heavy oil under oxygen-reduced conditions re...

  • Article
  • Open Access
82 Citations
6,696 Views
12 Pages

Zinc Oxide Nanoparticles Cytotoxicity and Release from Newly Formed PMMA–ZnO Nanocomposites Designed for Denture Bases

  • Mariusz Cierech,
  • Jacek Wojnarowicz,
  • Adam Kolenda,
  • Agata Krawczyk-Balska,
  • Emilia Prochwicz,
  • Bartosz Woźniak,
  • Witold Łojkowski and
  • Elżbieta Mierzwińska-Nastalska

15 September 2019

The goal of the study was to investigate the level of zinc oxide nanoparticles (ZnO NPs) release from polymethyl methacrylate (PMMA)–ZnO nanocomposites (2.5%, 5%, and 7.5% w/w), as well as from the ZnO NPs layer produced on pure PMMA, and the i...

  • Article
  • Open Access
22 Citations
3,762 Views
12 Pages

9 June 2021

Graphene oxide (GO) was proposed as an efficient carrier of antibiotics. The model drug, amoxicillin (AMOX), was attached to GO using a peptide linker (Leu-Leu-Gly). GO-AMOX was dispersed in a hydrogel to which the enzyme responsible for releasing AM...

  • Article
  • Open Access
1 Citations
1,981 Views
13 Pages

Green-Synthesized Zinc Oxide Nanoparticles with Enhanced Release Behavior for Sustainable Agricultural Applications

  • Riyad Al Sharif,
  • Ayman S. Ayesh,
  • Muayad Esaifan,
  • Naem Mazahrih,
  • Nabeel Bani Hani,
  • Bayan Al Rjoub,
  • Eva Rayya and
  • Majd Abu Salem

26 October 2025

This study presents a green and sustainable approach for synthesizing zinc oxide nanoparticles (ZnO-NPs) using Melia azedarach leaf extract as a reducing and stabilizing agent, with zinc acetate as the precursor. The synthesized nanoparticles were th...

  • Article
  • Open Access
20 Citations
7,839 Views
12 Pages

Nitrous Oxide Emission from Organic Fertilizer and Controlled Release Fertilizer in Tea Fields

  • Meihua Deng,
  • Mudan Hou,
  • Naoko Ohkama-Ohtsu,
  • Tadashi Yokoyama,
  • Haruo Tanaka,
  • Kenta Nakajima,
  • Ryosuke Omata and
  • Sonoko Dorothea Bellingrath-Kimura

A field experiment was conducted for two years in the Green Tea Laboratory of Saitama Prefectural Agriculture and Forestry Research Center, Iruma, Saitama, Japan from March 2014 to December 2015. Controlled release fertilizers (CRF) or organic fertil...

  • Feature Paper
  • Article
  • Open Access
33 Citations
4,696 Views
13 Pages

23 October 2019

Very recently, significant attention has been focused on the adsorption and cell adhesion properties of graphene oxide (GO), because it is expected to allow high drug loading and controlled drug release, as well as the promotion of cell adhesion and...

  • Review
  • Open Access
376 Views
26 Pages

Topical antibiotics have long been used for the prevention and treatment of superficial skin and soft tissue infections; however, increasing evidence indicates that their clinical value is undermined by rising antimicrobial resistance, high rates of...

  • Article
  • Open Access
68 Citations
7,446 Views
18 Pages

In Situ Hydrogel-Forming/Nitric Oxide-Releasing Wound Dressing for Enhanced Antibacterial Activity and Healing in Mice with Infected Wounds

  • Juho Lee,
  • Shwe Phyu Hlaing,
  • Jiafu Cao,
  • Nurhasni Hasan,
  • Hye-Jin Ahn,
  • Ki-Won Song and
  • Jin-Wook Yoo

The eradication of bacteria from wound sites and promotion of healing are essential for treating infected wounds. Nitric oxide (NO) is desirable for these purposes due to its ability to accelerate wound healing and its broad-spectrum antibacterial ef...

  • Article
  • Open Access
22 Citations
3,726 Views
24 Pages

30 November 2022

Intratumoral (IT) injection of chemotherapeutics into needle-accessible solid tumors can directly localize the anticancer drug in the tumor site, thus increasing its local bioavailability and reducing its undesirable effects compared to systemic admi...

  • Article
  • Open Access
10 Citations
3,131 Views
14 Pages

19 August 2021

The emergence of antibiotic-resistant “superbugs” in recent decades has led to widespread illness and death and is a major ongoing public health issue. Since traditional antimicrobials and antibiotics are in many cases showing limited or no effective...

  • Article
  • Open Access
53 Citations
6,139 Views
21 Pages

29 October 2018

Nanotechnology based drug delivery systems for cancer therapy have been the topic of interest for many researchers and scientists. In this research, we have studied the pH sensitive co-adsorption and release of doxorubicin (DOX) and paclitaxel (PAX)...

  • Article
  • Open Access
3 Citations
2,453 Views
12 Pages

9 December 2023

Layered nickelate oxides containing Ni1+/Ni2+ are isoelectronic to Cu2+/Cu3+ compounds and of present interest with respect to recent findings of superconductivity in a series of different compositions. It is thereby questionable why superconductivit...

  • Article
  • Open Access
3 Citations
2,566 Views
25 Pages

Quantitative Chemical Composition, Anti-Oxidant Activity, and Inhibition of TNF Release by THP-1 Cells Induced by Extracts of Echinodorus macrophyllus and Echinodorus grandiflorus

  • Marina Pereira Rocha,
  • Lyandra Maciel Cabral da Silva,
  • Laura Paulino Maia Silva,
  • José Hugo de Sousa Gomes,
  • Rodrigo Maia de Pádua,
  • João Aguiar Nogueira Batista,
  • Marcelo Martins Sena,
  • Priscilla Rodrigues Valadares Campana and
  • Fernão Castro Braga

This study investigated the similarities between Echinodorus macrophyllus and Echinodorus grandiflorus, plant species that are traditionally used in Brazil to treat rheumatism and arthritis, whose anti-inflammatory effects are supported by scientific...

  • Article
  • Open Access
4 Citations
2,196 Views
12 Pages

30 September 2023

Sustained-release materials are increasingly being used in the delivery of oxidants for in situ chemical oxidation (ISCO) for groundwater remediation. Successful implementation of sustained-release materials depends on a clear understanding of the me...

  • Article
  • Open Access
12 Citations
2,962 Views
15 Pages

Inducible Nitric Oxide Synthase Embedded in Alginate/Polyethyleneimine Hydrogel as a New Platform to Explore NO-Driven Modulation of Biological Function

  • Shaimaa Maher,
  • Lauren A. Smith,
  • Celine A. El-Khoury,
  • Haitham Kalil,
  • Khalid Sossey-Alaoui and
  • Mekki Bayachou

7 February 2023

Nitric oxide (NO), a small free radical molecule, turned out to be pervasive in biology and was shown to have a substantial influence on a range of biological activities, including cell growth and apoptosis. This molecule is involved in signaling and...

  • Article
  • Open Access
9 Citations
2,925 Views
12 Pages

20 February 2024

Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia caused by abnormalities in insulin secretion and/or action. In patients with diabetes, complications such as blindness, delayed wound healing, erectile dysfunction, renal fa...

  • Article
  • Open Access
2 Citations
1,137 Views
20 Pages

Microbially Mediated Arsenic-Nitrogen Biogeochemical Coupling Across Vertical Distribution in Coastal Wetlands

  • Yang Zou,
  • Lili Xue,
  • Ting Luo,
  • Sheng Kong,
  • Zirui Zhao,
  • Liang Ding,
  • Kexin Liu,
  • Huaxin Gao and
  • Hao Wu

23 April 2025

Few studies have addressed the coupling of arsenic (As) and nitrogen (N) geochemistry in natural soil. This research focused on the vertical distribution and coupling behavior of As and N in coastal wetland sediments. Pore water and sediment from bar...

  • Article
  • Open Access
22 Citations
3,915 Views
14 Pages

15 February 2021

The development of controlled drug delivery systems based on bio-renewable materials is an emerging strategy. In this work, a controlled drug delivery system based on mesoporous oxidized cellulose beads (OCBs) was successfully developed by a facile a...

  • Article
  • Open Access
7 Citations
2,692 Views
15 Pages

Effects of Zinc Addition on the Corrosion Behavior of Pre-Filmed Alloy 690 in Borated and Lithiated Water at 330 °C

  • Soon-Hyeok Jeon,
  • Dong-Seok Lim,
  • Jinsoo Choi,
  • Kyu-Min Song,
  • Jong-Hyeon Lee and
  • Do-Haeng Hur

23 July 2021

The purpose of this work is to quantify the effects of dissolved zinc cations on corrosion and release rates from a pre-filmed Alloy 690 steam generator tubing material that was subsequently exposed to water containing zinc. The corrosion tests were...

  • Article
  • Open Access
15 Citations
4,615 Views
24 Pages

Causation of Oxidative Stress and Defense Response of a Yeast Cell Model after Treatment with Orthodontic Alloys Consisting of Metal Ions

  • Vito Kovač,
  • Matic Bergant,
  • Janez Ščančar,
  • Jasmina Primožič,
  • Polona Jamnik and
  • Borut Poljšak

28 December 2021

Misaligned teeth have a tremendous impact on oral and dental health, and the most efficient method of correcting the problem is orthodontic treatment with orthodontic appliances. The study was conducted to investigate the metal composition of selecte...

  • Article
  • Open Access
19 Citations
3,738 Views
18 Pages

Airway Exposure to Polyethyleneimine Nanoparticles Induces Type 2 Immunity by a Mechanism Involving Oxidative Stress and ATP Release

  • Yotesawee Srisomboon,
  • Noriyuki Ohkura,
  • Koji Iijima,
  • Takao Kobayashi,
  • Peter J. Maniak,
  • Hirohito Kita and
  • Scott M. O’Grady

23 August 2021

Polyethyleneimine (PEI) induced immune responses were investigated in human bronchial epithelial (hBE) cells and mice. PEI rapidly induced ATP release from hBE cells and pretreatment with glutathione (GSH) blocked the response. PEI activated two cond...

  • Review
  • Open Access
6 Citations
2,445 Views
22 Pages

The final recipient of nanoparticles, including various types of copper-based nanoparticles (Cu-based NPs), is the aquatic environment. Their increased production, especially as a component of antimicrobial agents, raises concerns about uncontrolled...

  • Article
  • Open Access
1,581 Views
18 Pages

Ion Release from Endodontic and Restorative Dental Materials: Effects of pH and Time

  • Zbigniew Raszewski,
  • Katarzyna Chojnacka,
  • Małgorzata Ponto-Wolska and
  • Marcin Mikulewicz

22 April 2025

Background: Root canal sealers remain in long-term contact with dental tissues, raising concerns about their potential adverse effects. Methods: This study evaluates the physicochemical properties and ion-release profiles of three dental materials: z...

  • Article
  • Open Access
2 Citations
3,120 Views
15 Pages

Modulating the Release Kinetics of Natural Product Actinomycin from Bacterial Nanocellulose Films and Their Antimicrobial Activity

  • Katarzyna Zimowska,
  • Vuk Filipovic,
  • Jasmina Nikodinovic-Runic,
  • Jelena Simic,
  • Tatjana Ilic-Tomic,
  • Malgorzata Zimowska,
  • Jacek Gurgul and
  • Marijana Ponjavic

The present study aimed to create a more sustainable and controlled delivery system based on natural biopolymer bacterial nanocellulose (BNC) and bacterial natural product actinomycin (Act), with the applicative potential in the biomedical field. In...

  • Article
  • Open Access
5 Citations
2,378 Views
19 Pages

Developing a Slow-Release Permanganate Composite for Degrading Aquaculture Antibiotics

  • Chainarong Sakulthaew,
  • Chanat Chokejaroenrat,
  • Sidaporn Panya,
  • Apisit Songsasen,
  • Kitipong Poomipuen,
  • Saksit Imman,
  • Nopparat Suriyachai,
  • Torpong Kreetachat and
  • Steve Comfort

Copious use of antibiotics in aquaculture farming systems has resulted in surface water contamination in some countries. Our objective was to develop a slow-release oxidant that could be used in situ to reduce antibiotic concentrations in discharges...

  • Article
  • Open Access
35 Citations
5,971 Views
16 Pages

Release Behaviors of Arsenic and Heavy Metals from Arsenic Sulfide Sludge during Simulated Storage

  • Liwei Yao,
  • Xiaobo Min,
  • Yong Ke,
  • Yunyan Wang,
  • Yanjie Liang,
  • Xu Yan,
  • Hui Xu,
  • Jiangchi Fei,
  • Yuancheng Li and
  • Kang Yang
  • + 1 author

23 February 2019

Non-ferrous metal smelting enterprises produce hundreds of thousands of tons of arsenic sulfide sludge (ASS) each year in China. Most of the ASS are stored at the companies without enough preventive measures. During the storage and natural drying pro...

  • Article
  • Open Access
5 Citations
2,048 Views
12 Pages

16 October 2024

Introduction: Obesity is one of the major healthcare challenges. It affects one in eight people around the world and leads to several comorbidities, including type 2 diabetes, hyperlipidemia, and arterial hypertension. GLP-1 analogs have become major...

  • Article
  • Open Access
1 Citations
928 Views
19 Pages

In this study, the influence of (i) the degree of crosslinking and (ii) incorporating small amounts of graphene oxide—up to 0.2% by mass—into the matrix of ultra-porous hyaluronic acid scaffolds was analyzed in relation to their physicoch...

  • Article
  • Open Access
5 Citations
2,668 Views
20 Pages

Hybrid Membranes of the Ureasil-Polyether Containing Glucose for Future Application in Bone Regeneration

  • Camila Garcia da Silva,
  • João Rodrigues Monteiro,
  • João Augusto Oshiro-Júnior and
  • Leila Aparecida Chiavacci

The application of mesenchymal stem cells (MSC) in bone tissue regeneration can have unpredictable results due to the low survival of cells in the process since the lack of oxygen and nutrients promotes metabolic stress. Therefore, in this work, poly...

  • Article
  • Open Access
6 Citations
2,543 Views
14 Pages

Iron Oxides Nanoparticles as Components of Ferroptosis-Inducing Systems: Screening of Potential Candidates

  • Artur Dzeranov,
  • Lyubov Bondarenko,
  • Denis Pankratov,
  • Mikhail Prokof‘ev,
  • Gulzhian Dzhardimalieva,
  • Sharipa Jorobekova,
  • Nataliya Tropskaya,
  • Ludmila Telegina and
  • Kamila Kydralieva

This study presents an analysis of a set of iron oxides nanoparticles (NPs) (γ-Fe2O3, α-FeOOH, δ-FeOOH, 5Fe2O3·9H2O, and Fe3O4) as potential candidates for ferroptosis therapy in terms of a phase state, magnetic characteristi...

  • Article
  • Open Access
708 Views
44 Pages

Nanoencapsulated Dunaliella tertiolecta Extract and β-Carotene in Liposomal Carriers: Antioxidant and Erythroprotective Potential Through Sustained-Release Systems

  • Jonathan García-Morales,
  • Ricardo Iván González-Vega,
  • Diana Fimbres-Olivarría,
  • Ariadna Thalía Bernal-Mercado,
  • Santiago Pedro Auobourg-Martínez,
  • Karla Alejandra López-Gastélum,
  • Silvia Elena Burruel-Ibarra,
  • María Irene Silvas-García,
  • Andrea Grijalva-Molina and
  • Carmen Lizette Del-Toro-Sánchez
  • + 1 author

29 September 2025

The nanoencapsulation of bioactive compounds such as β-carotene and microalgal extracts has emerged as an effective strategy to enhance their stability, bioavailability, and biological efficacy, particularly against oxidative stress. Dunaliella ...

  • Article
  • Open Access
7 Citations
1,490 Views
15 Pages

Background: Isofraxidin is a hydroxylcoumarin derived from herbal Fraxinus and Eleutherococcus. It has been shown that isofraxidin has antioxidant, anti-inflammatory, anti-diabetic, and anti-lipidemic effects. The study aimed to examine the therapeut...

  • Article
  • Open Access
11 Citations
7,060 Views
15 Pages

DNA Cleavage and Condensation Activities of Mono- and Binuclear Hybrid Complexes and Regulation by Graphene Oxide

  • Shuo Li,
  • Mingxing Dai,
  • Chunping Zhang,
  • Bingying Jiang,
  • Junqiang Xu,
  • Dewen Zhou and
  • Zhongwei Gu

Hybrid complexes with N,N′-bis(2-benzimidazolylmethyl)amine and cyclen moieties are novel enzyme mimics and controlled DNA release materials, which could interact with DNA through three models under different conditions. In this paper, the interactio...

  • Article
  • Open Access
15 Citations
7,490 Views
22 Pages

Sleep Deprivation Triggers Mitochondrial DNA Release in Microglia to Induce Neural Inflammation: Preventative Effect of Hydroxytyrosol Butyrate

  • Yachong Hu,
  • Yongyao Wang,
  • Yifang Wang,
  • Yuxia Zhang,
  • Zhen Wang,
  • Xiaohong Xu,
  • Tinghua Zhang,
  • Tiantian Zhang,
  • Shuangxi Zhang and
  • Jiangang Long
  • + 8 authors

Sleep deprivation (SD) triggers mitochondrial dysfunction and neural inflammation, leading to cognitive impairment and mental issues. However, the mechanism involving mitochondrial dysfunction and neural inflammation still remains unclear. Here, we r...

  • Article
  • Open Access
5 Citations
3,259 Views
15 Pages

Microbiological-Chemical Sourced Chondroitin Sulfates Protect Neuroblastoma SH-SY5Y Cells against Oxidative Stress and Are Suitable for Hydrogel-Based Controlled Release

  • Emiliano Bedini,
  • Alfonso Iadonisi,
  • Chiara Schiraldi,
  • Laura Colombo,
  • Diego Albani,
  • Paola Petrini,
  • Carmen Giordano and
  • Marta Tunesi

16 November 2021

Chondroitin sulfates (CS) are a class of sulfated glycosaminoglycans involved in many biological processes. Several studies reported their protective effect against neurodegenerative conditions like Alzheimer’s disease. CS are commonly derived from a...

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