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4,431 Results Found

  • Editorial
  • Open Access
77 Citations
6,369 Views
4 Pages

Plant Natural Products for Human Health

  • Chun-Tao Che and
  • Hongjie Zhang

15 February 2019

The aim of this Special Issue on “Plant Natural Products for Human Health” is to compile a series of scientific reports to demonstrate the medicinal potential of plant natural products, such as in vitro and in vivo activities, clinical ef...

  • Review
  • Open Access
96 Citations
17,403 Views
52 Pages

Natural Products from Chinese Medicines with Potential Benefits to Bone Health

  • Chun-Tao Che,
  • Man Sau Wong and
  • Christopher Wai Kei Lam

27 February 2016

Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass and microstructure, leading to reduced bone strength and increased risk of fracture. It is often associated with reduced quality of life and other medical compli...

  • Abstract
  • Open Access
38 Citations
230 Views

1 August 2008

The use of complementary and alternative medicine (cam), including the ingestion of natural health products (nhps), is common among cancer patients. Of concern to clinicians and patients alike is the possibility that cam, used concurrently with biome...

  • Review
  • Open Access
993 Views
30 Pages

Effects of Natural Health Products in Combination with FP-Based Chemotherapy

  • Valeria Conti,
  • Berenice Stefanelli,
  • Carmineantonio Romeo,
  • Alessandra De Stefano,
  • Dominga Valentino,
  • Graziamaria Corbi,
  • Francesco Sabbatino,
  • Emanuela De Bellis and
  • Amelia Filippelli

20 November 2025

Background: Cancer patients often use natural health products (NHPs) during chemotherapy without medical supervision. We have previously described the clinical cases of two patients taking capecitabine in combination with folate supplements who suffe...

  • Review
  • Open Access
28 Citations
14,669 Views
29 Pages

Natural Pigments Recovery from Food By-Products: Health Benefits towards the Food Industry

  • Daniela Magalhães,
  • Ricardo Gonçalves,
  • Cristina V. Rodrigues,
  • Helena R. Rocha,
  • Manuela Pintado and
  • Marta C. Coelho

19 July 2024

Given the health risks associated with synthetic colorants, natural pigments have emerged as a promising alternative. These renewable choices not only provide health benefits but also offer valuable technical and sensory properties to food systems. T...

  • Article
  • Open Access
17 Citations
6,448 Views
15 Pages

Impacts of Diverse Natural Products on Honey Bee Viral Loads and Health

  • Dawn L. Boncristiani,
  • James P. Tauber,
  • Evan C. Palmer-Young,
  • Lianfei Cao,
  • William Collins,
  • Kyle Grubbs,
  • Jillian A. Lopez,
  • Lyndel W. Meinhardt,
  • Vy Nguyen and
  • Jay D. Evans
  • + 4 authors

13 November 2021

Western honey bees (Apis mellifera), a cornerstone to crop pollination in the U.S., are faced with an onslaught of challenges from diseases caused by parasites, pathogens, and pests that affect this economically valuable pollinator. Natural products...

  • Review
  • Open Access
49 Citations
7,969 Views
32 Pages

Natural Health Products (NHP’s) and Natural Compounds as Therapeutic Agents for the Treatment of Cancer; Mechanisms of Anti-Cancer Activity of Natural Compounds and Overall Trends

  • Benjamin Scaria,
  • Siddhartha Sood,
  • Christopher Raad,
  • Jana Khanafer,
  • Rahul Jayachandiran,
  • Alaina Pupulin,
  • Sahibjot Grewal,
  • Michael Okoko,
  • Mansi Arora and
  • Siyaram Pandey
  • + 1 author

11 November 2020

Most cancer therapeutics, such as tubulin-targeting chemotherapy drugs, cause cytotoxic, non-selective effects. These harmful side-effects drastically reduce the cancer patient’s quality of life. Recently, researchers have focused their efforts on st...

  • Review
  • Open Access
165 Citations
2,633 Views
1 Page

1 February 2006

An integrative approach for managing a patient with cancer should target the multiple biochemical and physiologic pathways that support tumour development and minimize normal-tissue toxicity. Angiogenesis is a key process in the promotion of cancer....

  • Review
  • Open Access
44 Citations
1,298 Views
9 Pages

1 June 2006

The herbalist has access to hundreds of years of observational data on the anticancer activity of many herbs. Laboratory studies are expanding the clinical knowledge that is already documented in traditional texts. The herbs that are traditionally us...

  • Editorial
  • Open Access
17 Citations
2,869 Views
5 Pages

Functional Properties of Natural Products and Human Health

  • Paola Bontempo,
  • Luigi De Masi and
  • Daniela Rigano

29 June 2023

Natural products (NPs), broadly defined as chemicals produced by living organisms including microbes, marine organisms, animals, fungi and plants, are widely used as therapeutic agents for treating diseases and maintaining health and “wellness&...

  • Article
  • Open Access
1 Citations
3,202 Views
12 Pages

From Prescription Drugs to Natural Health Products: Medication Use in Canadian Infants

  • Pascal Bedard,
  • Geoffrey L. Winsor,
  • Emma S. Garlock,
  • Meghan B. Azad,
  • Allan B. Becker,
  • Piush J. Mandhane,
  • Theo J. Moraes,
  • Malcolm R. Sears,
  • Stuart E. Turvey and
  • Anita L. Kozyrskyj
  • + 2 authors

27 September 2022

Limited data exist on pharmaceutical product use by infants, although available data suggests higher prevalence of use among children under 12 months of age. We conducted a descriptive study of 3050 infants recruited in the CHILD Cohort Study, a pros...

  • Review
  • Open Access
25 Citations
6,481 Views
20 Pages

RETRACTED: Honeybee and Plant Products as Natural Antimicrobials in Enhancement of Poultry Health and Production

  • Erinda Lika,
  • Marija Kostić,
  • Sunčica Vještica,
  • Ivan Milojević and
  • Nikola Puvača

29 July 2021

The quality and safety attributes of poultry products have attracted increasing widespread attention and interest from scholarly groups and the general population. As natural and safe alternatives to synthetic and artificial chemical drugs (e.g., ant...

  • Review
  • Open Access
93 Citations
15,438 Views
22 Pages

Euphorbia-Derived Natural Products with Potential for Use in Health Maintenance

  • Bahare Salehi,
  • Marcello Iriti,
  • Sara Vitalini,
  • Hubert Antolak,
  • Ewelina Pawlikowska,
  • Dorota Kręgiel,
  • Javad Sharifi-Rad,
  • Sunday I. Oyeleye,
  • Adedayo O. Ademiluyi and
  • Ana M. L. Seca
  • + 8 authors

2 August 2019

Euphorbia genus (Euphorbiaceae family), which is the third largest genus of angiosperm plants comprising ca. 2000 recognized species, is used all over the world in traditional medicine, especially in the traditional Chinese medicine. Members of this...

  • Feature Paper
  • Concept Paper
  • Open Access
16 Citations
7,235 Views
16 Pages

Novel Natural Products for Healthy Ageing from the Mediterranean Diet and Food Plants of Other Global Sources—The MediHealth Project

  • Birgit Waltenberger,
  • Maria Halabalaki,
  • Stefan Schwaiger,
  • Nicolas Adamopoulos,
  • Noureddine Allouche,
  • Bernd L. Fiebich,
  • Nina Hermans,
  • Pidder Jansen-Dürr,
  • Victor Kesternich and
  • Hermann Stuppner
  • + 9 authors

There is a rapid increase in the percentage of elderly people in Europe. Consequently, the prevalence of age-related diseases will also significantly increase. Therefore, the main goal of MediHealth, an international research project, is to introduce...

  • Review
  • Open Access
9 Citations
8,548 Views
31 Pages

Natural Health Products for Anti-Cancer Treatment: Evidence and Controversy

  • Valeria Conti,
  • Giovanna Polcaro,
  • Emanuela De Bellis,
  • Danilo Donnarumma,
  • Federica De Rosa,
  • Berenice Stefanelli,
  • Graziamaria Corbi,
  • Francesco Sabbatino and
  • Amelia Filippelli

26 June 2024

Natural Health Products (NHPs) have long been considered a valuable therapeutic approach for the prevention and treatment of various diseases, including cancer. However, research on this topic has led to inconclusive and often controversial results....

  • Retraction
  • Open Access
490 Views
1 Page

31 July 2025

The journal retracts the article titled “Honeybee and Plant Products as Natural Antimicrobials in Enhancement of Poultry Health and Production” [...]

  • Meeting Report
  • Open Access
2 Citations
14,271 Views
50 Pages

10 October 2014

The 5th International Conference on Natural Products for Health and Beauty (NATPRO 5) was held at the Moevenpick Resort and Spa Karon Beach, Phuket, Thailand on 6–8 May 2014. NATPRO was established in 2005 by Professor Maitree Suttajit, Mahasarakham...

  • Systematic Review
  • Open Access
2 Citations
7,464 Views
23 Pages

Natural Health Products in the Prevention and Management of Alzheimer’s Disease: A Systematic Review of Randomized Clinical Trials

  • Valeria Conti,
  • Adele Zarrella,
  • Danilo Donnarumma,
  • Annarita Pagano,
  • Ines Mazza,
  • Alessandra De Stefano,
  • Francesca Gallo,
  • Valeria Di Landri,
  • Domenico De Pascale and
  • Amelia Filippelli
  • + 4 authors

23 March 2025

Supplementation with natural compounds, referred to as Natural Health Products (NHPs), is emerging as an applicable strategy in all phases of Alzheimer’s disease (AD) management, alongside pharmacological therapy. Several studies have investiga...

  • Review
  • Open Access
19 Citations
5,656 Views
17 Pages

Historical Aspects of Herbal Use and Comparison of Current Regulations of Herbal Products between Mexico, Canada and the United States of America

  • Patricia Rojas,
  • Helgi Jung-Cook,
  • Elizabeth Ruiz-Sánchez,
  • Irma Susana Rojas-Tomé,
  • Carolina Rojas,
  • Arely M. López-Ramírez and
  • Aldo Arturo Reséndiz-Albor

Increased life expectancy and high costs of medicines and medical care have led to the use of herbal products. However, these items may contain toxic compounds that have an impact on public health. We will focus on the regulatory aspects and differen...

  • Review
  • Open Access
4 Citations
8,565 Views
16 Pages

Natural Products and Health Care Functions of Inonotus obliquus

  • Yiming Wang,
  • Jingsheng Gu,
  • Jiaying Wu,
  • Yuxuan Xu,
  • Yiting Liu,
  • Fengxiu Li,
  • Qiao Liu,
  • Kailun Lu,
  • Ting Liang and
  • Jihong Jiang
  • + 3 authors

With the increasing attention of modern medicine to natural medicinal agents, Inonotus obliquus (chaga), a macrofungus with remarkable medicinal value, has gradually garnered widespread academic interest. This paper reviews the primary bioactive comp...

  • Review
  • Open Access
69 Citations
10,948 Views
30 Pages

From Ocean to Medicine: Pharmaceutical Applications of Metabolites from Marine Bacteria

  • José Diogo Santos,
  • Inês Vitorino,
  • Fernando Reyes,
  • Francisca Vicente and
  • Olga Maria Lage

Oceans cover seventy percent of the planet’s surface and besides being an immense reservoir of biological life, they serve as vital sources for human sustenance, tourism, transport and commerce. Yet, it is estimated by the National Oceanic and...

  • Review
  • Open Access
556 Citations
32,908 Views
43 Pages

15 February 2023

Phenolic compounds and flavonoids are potential substitutes for bioactive agents in pharmaceutical and medicinal sections to promote human health and prevent and cure different diseases. The most common flavonoids found in nature are anthocyanins, fl...

  • Review
  • Open Access
54 Citations
9,478 Views
29 Pages

Effects of Plant-Based Antioxidants in Animal Diets and Meat Products: A Review

  • Carmen Daniela Petcu,
  • Oana Diana Mihai,
  • Dana Tăpăloagă,
  • Raluca-Aniela Gheorghe-Irimia,
  • Elena Narcisa Pogurschi,
  • Manuella Militaru,
  • Cristin Borda and
  • Oana-Mărgărita Ghimpețeanu

21 March 2023

The perceived level of risk associated with a food product can influence purchase and consumption decisions. Thus, current trends in food safety address an issue of general interest—the identification of healthy and economical alternatives to s...

  • Article
  • Open Access
31 Citations
10,280 Views
17 Pages

Recent Progress in Perennial Buckwheat Development

  • Qing-Fu Chen,
  • Xiao-Yan Huang,
  • Hong-You Li,
  • Li-Juan Yang and
  • Ya-Song Cui

17 February 2018

Grains in the genus Fagopyrum have benefits to human health and are an excellent gluten-free raw material. Of all cereal foods, this genus has the highest total content of amino-acid nutrients necessary for humans; nutrients that are resistant to dig...

  • Review
  • Open Access
488 Citations
22,210 Views
41 Pages

Natural Bioactive Compounds from Winery By-Products as Health Promoters: A Review

  • Ana Teixeira,
  • Nieves Baenas,
  • Raul Dominguez-Perles,
  • Ana Barros,
  • Eduardo Rosa,
  • Diego A. Moreno and
  • Cristina Garcia-Viguera

4 September 2014

The relevance of food composition for human health has increased consumers’ interest in the consumption of fruits and vegetables, as well as foods enriched in bioactive compounds and nutraceuticals. This fact has led to a growing attention of supplie...

  • Article
  • Open Access
47 Citations
11,253 Views
30 Pages

Reconnecting Farmers with Nature through Agroecological Transitions: Interacting Niches and Experimentation and the Role of Agricultural Knowledge and Innovation Systems

  • Cynthia Giagnocavo,
  • Miguel de Cara-García,
  • Mónica González,
  • Melchor Juan,
  • José Ignacio Marín-Guirao,
  • Sepide Mehrabi,
  • Estefanía Rodríguez,
  • Jan van der Blom and
  • Eduardo Crisol-Martínez

Sustainability transitions in agriculture are explored through an analysis of niche initiatives within a common production system, relying on sustainable transitions, multi-level perspectives, and agroecological frameworks, and involving multi-actor,...

  • Perspective
  • Open Access
43 Citations
15,212 Views
31 Pages

30 September 2022

Specialized products can be needed to help meet the nutrition requirements of vulnerable populations, including infants and young children, those who are ill, and older adults. Laws and regulations delineate distinct categories for such products incl...

  • Review
  • Open Access
1,052 Citations
61,296 Views
29 Pages

Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery

  • Nicholas Ekow Thomford,
  • Dimakatso Alice Senthebane,
  • Arielle Rowe,
  • Daniella Munro,
  • Palesa Seele,
  • Alfred Maroyi and
  • Kevin Dzobo

The therapeutic properties of plants have been recognised since time immemorial. Many pathological conditions have been treated using plant-derived medicines. These medicines are used as concoctions or concentrated plant extracts without isolation of...

  • Review
  • Open Access
4,242 Views
32 Pages

European Consumer and Regulatory Trends in Medicinal Plant Food Supplements and Their Functional Properties: The Road from Farm to Fork

  • Mihaela Mihai,
  • Călina Ciont,
  • Oana-Lelia Pop,
  • Diana E. Dumitras,
  • Valentin C. Mihai,
  • Ionela Daniela Morariu and
  • Cristina Bianca Pocol

30 October 2025

The rising use of medicinal plant food supplements in Europe reflects a growing consumer shift toward natural health solutions and sustainability-driven lifestyles. The study aims to synthesize current literature and regulatory frameworks to better u...

  • Perspective
  • Open Access
19 Citations
7,136 Views
23 Pages

Graphene and Natural Products: A Review of Antioxidant Properties in Graphene Oxide Reduction

  • Filipe Kayodè Felisberto dos Santos,
  • Antônio Augusto Martins Pereira Júnior,
  • Arquimedes Lopes Nunes Filho,
  • Clícia Joanna Neves Fonseca,
  • Daysianne Kessy Mendes Isidorio,
  • Filipe de Almeida Araújo,
  • Pablo Henrique Ataide Oliveira and
  • Valdir Florêncio da Veiga Júnior

This review article addresses the antioxidant properties of different natural products, including ascorbic acid, gallic acid, oxalic acid, L-glutathione (GSH), bacteriorhodopsin, green tea polyphenols, glucose, hydroxycinnamic acid, ethanoic acid, be...

  • Review
  • Open Access
1 Citations
1,471 Views
11 Pages

14 November 2025

Red palm oil (RPO) is a rich source of bioactive compounds, including carotenoids, tocopherols, tocotrienols, and polyphenols, which contribute to its potent antioxidant and anti-inflammatory properties. This review summarizes the current understandi...

  • Systematic Review
  • Open Access
2,057 Views
30 Pages

Natural Compounds in Oral Microbiota Modulation and Caries Prevention: A Systematic Review

  • María del Pilar Angarita-Díaz,
  • Lilia J. Bernal-Cepeda,
  • Jéssica María Sarmiento-Ordoñez,
  • Yohan Yañez-Navas,
  • Karen Garcia-Plazas,
  • Hermann Gutierrez-Reyes and
  • Laura Correa-Guataquira

5 November 2025

Background/Objectives: Certain components of natural products help maintain the oral microbiota balance, thereby promoting oral health. This study aimed to identify natural components with anticariogenic properties by analyzing evidence from in vivo...

  • Review
  • Open Access
33 Citations
8,266 Views
15 Pages

18 October 2022

The sanitization of hatching eggs is the backbone of the hygienic–sanitary management of eggs on farms and extends to the hatchery. Poultry production gains depend on the benefits of sanitizers. Obtaining the maximum yield from incubation free...

  • Article
  • Open Access
4 Citations
2,006 Views
14 Pages

Flower Species Ingredient Verification Using Orthogonal Molecular Methods

  • Subramanyam Ragupathy,
  • Arunachalam Thirugnanasambandam,
  • Thomas Henry,
  • Varathan Vinayagam,
  • Ragupathy Sneha and
  • Steven G. Newmaster

13 June 2024

Flowers are gaining considerable interest among consumers as ingredients in food, beverages, cosmetics, and natural health products. The supply chain trades in multiple forms of botanicals, including fresh whole flowers, which are easier to identify...

  • Proceeding Paper
  • Open Access
5 Citations
2,739 Views
6 Pages

Total Antioxidant Capacity and Phenolic Content of 17 Mediterranean Functional Herbs and Wild Green Extracts from North Aegean, Greece

  • Chrysoula Kaloteraki,
  • Kalliopi Almpounioti,
  • Panagiota Potsaki,
  • Panoraia Bousdouni,
  • Aikaterini Kandyliari and
  • Antonios E. Koutelidakis

Functional foods are considered beneficial to human health due to their high nutritional values. Currently, there is development in research to identify natural functional food sources high in bioactive compounds, such as antioxidants and polyphenols...

  • Editorial
  • Open Access
2,706 Views
9 Pages

Bioactive Natural and Synthetic Products in Human Health and Diseases: Basic, Preclinical and Clinical Studies

  • Felicite K. Noubissi,
  • Tolulope O. Omolekan,
  • Anthony L. Walker and
  • Jean Christopher Chamcheu

27 September 2024

Since the early 20th century, the increase in non-communicable diseases such as diabetes, heart disease, stroke, and cancer compared to infectious diseases has led to chronic illnesses becoming a leading cause of global morbidity and mortality [...]

  • Review
  • Open Access
42 Citations
13,795 Views
31 Pages

Novel Pharmacological Approaches to the Treatment of Depression

  • Elias Elias,
  • Ariel Y. Zhang and
  • Melissa T. Manners

28 January 2022

Major depressive disorder is one of the most prevalent mental health disorders. Monoamine-based antidepressants were the first drugs developed to treat major depressive disorder. More recently, ketamine and other analogues were introduced as fast-act...

  • Article
  • Open Access
24 Citations
5,117 Views
19 Pages

Phytochemical Study and In Vitro Screening Focusing on the Anti-Aging Features of Various Plants of the Greek Flora

  • Aimilia D. Sklirou,
  • Maria T. Angelopoulou,
  • Aikaterini Argyropoulou,
  • Eliza Chaita,
  • Vasiliki Ioanna Boka,
  • Christina Cheimonidi,
  • Katerina Niforou,
  • Eleni Mavrogonatou,
  • Harris Pratsinis and
  • Alexios Leandros Skaltsounis
  • + 4 authors

Skin health is heavily affected by ultraviolet irradiation from the sun. In addition, senile skin is characterized by major changes in the collagen, elastin and in the hyaluronan content. Natural products (NPs) have been shown to delay cellular senes...

  • Article
  • Open Access
3 Citations
4,567 Views
18 Pages

19 June 2020

The lack of effective treatment for chronic discomfort without negative side effects highlights the need for alternative treatments. Pain Bloc-R is a natural health product composed of vitamins B6, B12, D, white willow bark extract, Angelica root ext...

  • Review
  • Open Access
66 Citations
7,526 Views
22 Pages

Natural Polyphenol Recovery from Apple-, Cereal-, and Tomato-Processing By-Products and Related Health-Promoting Properties

  • Katalin Szabo,
  • Laura Mitrea,
  • Lavinia Florina Călinoiu,
  • Bernadette-Emőke Teleky,
  • Gheorghe Adrian Martău,
  • Diana Plamada,
  • Mihaela Stefana Pascuta,
  • Silvia-Amalia Nemeş,
  • Rodica-Anita Varvara and
  • Dan Cristian Vodnar

17 November 2022

Polyphenols of plant origin are a broad family of secondary metabolites that range from basic phenolic acids to more complex compounds such as stilbenes, flavonoids, and tannins, all of which have several phenol units in their structure. Considerable...

  • Review
  • Open Access
16 Citations
7,088 Views
32 Pages

A Review on Apple Pomace Bioactives for Natural Functional Food and Cosmetic Products with Therapeutic Health-Promoting Properties

  • Maria Vandorou,
  • Christos Plakidis,
  • Ilektra Maria Tsompanidou,
  • Theodora Adamantidi,
  • Eirini A. Panagopoulou and
  • Alexandros Tsoupras

9 October 2024

Apples are consumed lavishly worldwide, while demand is increasing for the management of the huge apple-waste amounts that lead to significant disposal costs and ecological issues. Additionally, apples represent fruits with several bioactive constitu...

  • Review
  • Open Access
105 Citations
20,100 Views
16 Pages

Cinnamon: A Natural Feed Additive for Poultry Health and Production—A Review

  • Akhtar Ali,
  • Eric N. Ponnampalam,
  • Gamini Pushpakumara,
  • Jeremy J. Cottrell,
  • Hafiz A. R. Suleria and
  • Frank R. Dunshea

7 July 2021

The increased bacterial resistance to synthetic antibiotics and consumer awareness about the health and food safety concerns have triggered the ban on the use of antibiotic growth promotors (AGPs) in the poultry industry. This situation encouraged th...

  • Review
  • Open Access
27 Citations
8,589 Views
21 Pages

Exploring the Potential of Natural Product-Based Nanomedicine for Maintaining Oral Health

  • Rajeev Kumar,
  • Mohd A. Mirza,
  • Punnoth Poonkuzhi Naseef,
  • Mohamed Saheer Kuruniyan,
  • Foziyah Zakir and
  • Geeta Aggarwal

Oral diseases pose a major threat to public health across the globe. Diseases such as dental caries, periodontitis, gingivitis, halitosis, and oral cancer affect people of all age groups. Moreover, unhealthy diet practices and the presence of comorbi...

  • Review
  • Open Access
5 Citations
7,858 Views
24 Pages

Cranberry: A Promising Natural Product for Animal Health and Performance

  • Sahdeo Prasad,
  • Bhaumik Patel,
  • Prafulla Kumar,
  • Pranabendu Mitra and
  • Rajiv Lall

Cranberries are a distinctive source of bioactive compounds, containing polyphenols such as flavonoids, anthocyanins, phenolic acids, and triterpenoids. Cranberries are often associated with potential health benefits for the urinary tract and digesti...

  • Review
  • Open Access
35 Citations
38,726 Views
28 Pages

Avocado and Its By-Products as Natural Sources of Valuable Anti-Inflammatory and Antioxidant Bioactives for Functional Foods and Cosmetics with Health-Promoting Properties

  • Anita Marra,
  • Vasileios Manousakis,
  • Georgios Panagiotis Zervas,
  • Nikolaos Koutis,
  • Marios Argyrios Finos,
  • Theodora Adamantidi,
  • Ellie Panoutsopoulou,
  • Anna Ofrydopoulou and
  • Alexandros Tsoupras

9 July 2024

Avocado (Persea americana) is a unique fruit with exceptional nutritional and technological characteristics, as well as proposed health benefits. Moreover, the commercial utilization of avocado to make guacamole and/or to extract its oil for several...

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