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Open AccessReview

Euphorbia-Derived Natural Products with Potential for Use in Health Maintenance

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Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam 44340847, Iran
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Department of Agricultural and Environmental Sciences, Milan State University, via G. Celoria 2, 20133 Milan, Italy
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Institute of Fermentation Technology and Microbiology, Lodz University of Technology, Wolczanska 171/173, 90-924 Lodz, Poland
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Zabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol 61615-585, Iran
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Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, Akure 340252, Nigeria
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Department of Biomedical Technology, Federal University of Technology, Akure 340252, Nigeria
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Institute of Soil Science and Plant Cultivation – State Research Institute, Czartoryskich 8, 24-100 Puławy, Poland
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Centre of Marine Sciences, University of Algarve, Faculty of Sciences and Technology, Building 7, Campus of Gambelas, 8005-139 Faro, Portugal
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Bioorganic Chemistry Laboratory, Facultad de Ciencias Básicas y Aplicadas, Universidad Militar Nueva Granada, Campus Nueva Granada, Cajicá 250247, Colombia
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Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avda. Fuentenueva s/n, 18071 Granada, Spain
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Research and Development Functional Food Centre (CIDAF), Bioregión Building, Health Science Technological Park, Avenida del Conocimiento s/n, 188016 Granada, Spain
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Department of Agricultural Sciences, University of Naples Federico II, 80055 Portici, Italy
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Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong SAR, China
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cE3c- Centre for Ecology, Evolution and Environmental Changes/ Azorean Biodiversity Group & University of Azores, Rua Mãe de Deus, 9501-801 Ponta Delgada, Portugal
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QOPNA & LAQV-REQUIMTE, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal
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Authors to whom correspondence should be addressed.
Biomolecules 2019, 9(8), 337; https://doi.org/10.3390/biom9080337
Received: 2 July 2019 / Revised: 29 July 2019 / Accepted: 1 August 2019 / Published: 2 August 2019
Euphorbia genus (Euphorbiaceae family), which is the third largest genus of angiosperm plants comprising ca. 2000 recognized species, is used all over the world in traditional medicine, especially in the traditional Chinese medicine. Members of this taxa are promptly recognizable by their specialized inflorescences and latex. In this review, an overview of Euphorbia-derived natural products such as essential oils, extracts, and pure compounds, active in a broad range of biological activities, and with potential usages in health maintenance, is described. The chemical composition of essential oils from Euphorbia species revealed the presence of more than 80 phytochemicals, mainly oxygenated sesquiterpenes and sesquiterpenes hydrocarbons, while Euphorbia extracts contain secondary metabolites such as sesquiterpenes, diterpenes, sterols, flavonoids, and other polyphenols. The extracts and secondary metabolites from Euphorbia plants may act as active principles of medicines for the treatment of many human ailments, mainly inflammation, cancer, and microbial infections. Besides, Euphorbia-derived products have great potential as a source of bioactive extracts and pure compounds, which can be used to promote longevity with more health. View Full-Text
Keywords: Euphorbia; essential oils; extracts; phytochemicals; terpenoids; bioactivity; antimicrobial; anti-inflammation; anticancer Euphorbia; essential oils; extracts; phytochemicals; terpenoids; bioactivity; antimicrobial; anti-inflammation; anticancer
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MDPI and ACS Style

Salehi, B.; Iriti, M.; Vitalini, S.; Antolak, H.; Pawlikowska, E.; Kręgiel, D.; Sharifi-Rad, J.; Oyeleye, S.I.; Ademiluyi, A.O.; Czopek, K.; Staniak, M.; Custódio, L.; Coy-Barrera, E.; Segura-Carretero, A.; Cádiz-Gurrea, M.L.; Capasso, R.; Cho, W.C.; Seca, A.M.L. Euphorbia-Derived Natural Products with Potential for Use in Health Maintenance. Biomolecules 2019, 9, 337.

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