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  • Article
  • Open Access
2 Citations
1,931 Views
11 Pages

Effect of Licorice on Gene Expression Related to the Growth of Asian Seabass Lates calcarifer

  • Rui Yang,
  • Wang Zhao,
  • Yifu Wang,
  • Zhengyi Fu,
  • Jing Hu,
  • Shengjie Zhou,
  • Minghao Li and
  • Zhenhua Ma

The Asian seabass (Lates calcarifer) has high economic value and is the primary aquaculture species in China. Licorice (Glycyrrhiza uralensis) as a feed additive has demonstrated significant immunological benefits in aquaculture. However, its effects...

  • Article
  • Open Access
8 Citations
2,999 Views
12 Pages

20 April 2022

The improvements in muscle growth rate and meat quality are the major breeding aims in pigeon industry. Liver and muscle are recognized as important sites for fatty acid metabolism; understanding the role of specific transcripts in the breast muscle...

  • Article
  • Open Access
2,283 Views
18 Pages

26 October 2024

The pikeperch (Sander lucioperca) is an economically important freshwater fish and a valuable food with high market acceptance. It is undergoing important changes in growth and regulatory metabolism during the ontogeny. Hence, the current study aims...

  • Article
  • Open Access
20 Citations
5,565 Views
14 Pages

Promising Role of Growth Hormone-Boosting Peptide in Regulating the Expression of Muscle-Specific Genes and Related MicroRNAs in Broiler Chickens

  • Doaa Ibrahim,
  • Hanan S. Al-Khalaifah,
  • Ahmed Abdelfattah-Hassan,
  • Haitham Eldoumani,
  • Safaa I. Khater,
  • Ahmed H. Arisha,
  • Sally A. M. Mohamed,
  • Tamer Ahmed Ismail and
  • Samar A. Tolba

26 June 2021

Appropriate skeletal muscle development in poultry is positively related to increasing its meat production. Synthetic peptides with growth hormone-boosting properties can intensify the effects of endogenous growth hormones. However, their effects on...

  • Article
  • Open Access
3 Citations
2,869 Views
26 Pages

The Effect of 17α-Ethynilestradiol and GPER1 Activation on Body and Muscle Growth, Muscle Composition and Growth-Related Gene Expression of Gilthead Seabream, Sparus aurata L

  • Maria D. Ayala,
  • Victoria Gómez,
  • Isabel Cabas,
  • María P. García Hernández,
  • Elena Chaves-Pozo,
  • Marta Arizcun,
  • Daniel Garcia de la Serrana,
  • Francisco Gil and
  • Alfonsa García-Ayala

4 December 2021

Endocrine-disrupting chemicals include natural and synthetic estrogens, such as 17α-ethynilestradiol (EE2), which can affect reproduction, growth and immunity. Estrogen signalling is mediated by nuclear or membrane estrogen receptors, such as t...

  • Article
  • Open Access
21 Citations
4,830 Views
15 Pages

18 December 2023

An 8-week feeding trial was conducted to assess the effects on growth, antioxidant capacity, digestive enzyme activity, and gene expression related to muscle growth and protein synthesis of juvenile greasyback shrimp (Metapenaeus ensis) using five ex...

  • Article
  • Open Access
132 Views
18 Pages

Expression Profiles of Growth-Related Genes in CRISPR/Cas9-Mediated MRF4-Crispant Nile Tilapia

  • Zahid Parvez Sukhan,
  • Yusin Cho,
  • Doohyun Cho,
  • Cheol Young Choi and
  • Kang Hee Kho

14 January 2026

Genome editing of late myogenic regulators provides a way to dissect the mechanisms through which transcriptional programs and growth-related signaling pathways shape muscle gene expression programs in farmed fish. This study disrupted myogenic regul...

  • Article
  • Open Access
34 Citations
8,286 Views
17 Pages

Integrative Transcriptome, Genome and Quantitative Trait Loci Resources Identify Single Nucleotide Polymorphisms in Candidate Genes for Growth Traits in Turbot

  • Diego Robledo,
  • Carlos Fernández,
  • Miguel Hermida,
  • Andrés Sciara,
  • José Antonio Álvarez-Dios,
  • Santiago Cabaleiro,
  • Rubén Caamaño,
  • Paulino Martínez and
  • Carmen Bouza

17 February 2016

Growth traits represent a main goal in aquaculture breeding programs and may be related to adaptive variation in wild fisheries. Integrating quantitative trait loci (QTL) mapping and next generation sequencing can greatly help to identify variation i...

  • Article
  • Open Access
10 Citations
3,499 Views
22 Pages

12 August 2022

Improvements in growth-related traits reduce fish time and production costs to reach market size. Feed deprivation and refeeding cycles have been introduced to maximize aquaculture profits through compensatory growth. However, the molecular compensat...

  • Article
  • Open Access
2 Citations
1,782 Views
13 Pages

2 February 2025

Growth traits are among the most important economic phenotypes targeted in the genetic improvement of beef cattle. To understand the genetic basis of growth traits in Huaxi cattle, we performed a genome-wide association study (GWAS) on body weight, e...

  • Article
  • Open Access
39 Citations
5,184 Views
12 Pages

Effects of Essential Oil Derived from the Bitter Orange (Citrus aurantium) on Growth Performance, Histology and Gene Expression Levels in Common Carp Juveniles (Cyprinus carpio)

  • Ümit Acar,
  • Osman Sabri Kesbiç,
  • Sevdan Yılmaz,
  • Burak Evren İnanan,
  • Fahriye Zemheri-Navruz,
  • Funda Terzi,
  • Francesco Fazio and
  • Vincenzo Parrino

17 May 2021

The aim of this study was to detect effects of bitter orange (Citrus aurantium) essential oil, commonly called neroli oil (NO) (0, 0.25, 0.50, 1, and 1.5% referred to as NO0 NO0.25, NO0. 05, NO1 and NO1.5, respectively) on growth performance output a...

  • Article
  • Open Access
4 Citations
2,146 Views
14 Pages

Effects of Dietary Gallic Acid on Growth Performance, Meat Quality, Antioxidant Capacity, and Muscle Fiber Type-Related Gene Expression in Broiler Chickens Challenged with Lipopolysaccharide

  • Taidi Xiong,
  • Zhilong Chen,
  • Mubashar Hassan,
  • Cui Zhu,
  • Junyan Wang,
  • Shujun Tan,
  • Fayuan Ding,
  • Zhonggang Cheng,
  • Jinling Ye and
  • Dong Ruan
  • + 3 authors

19 December 2024

In this study, broilers were selected as the research object to investigate the effects and mechanisms of dietary gallic acid (GA) supplementation on growth performance, meat quality, antioxidant capacity, and muscle fiber-related gene expression. A...

  • Article
  • Open Access
11 Citations
3,398 Views
8 Pages

Association between Single Nucleotide Polymorphisms in SIRT1 and SIRT2 Loci and Growth in Tibetan Sheep

  • Lin-sheng Gui,
  • Sayed Haidar Abbas Raza,
  • Li Zhou,
  • Matthew Garcia,
  • Ayman Hassan Abd El-Aziz,
  • Dawei Wei,
  • Shengzhen Hou,
  • Jianlei Jia and
  • Zhiyou Wang

6 August 2020

Silent information regulator 1 and 2 (SIRT1, 2) were NAD+-dependent histone or non-histone deacetylase, which emerged as key metabolic sensors in several tissues of mammals. In the present study, the search for polymorphisms within the ovine SIRT1 an...

  • Article
  • Open Access
6 Citations
3,217 Views
11 Pages

miR-708-5p Regulates Myoblast Proliferation and Differentiation

  • Xueli Xu,
  • Hui Lu,
  • Dong Xu,
  • Zonggang Yu,
  • Nini Ai,
  • Kaiming Wang,
  • Xintong Li,
  • Jun He,
  • Jun Jiang and
  • Yuebo Zhang
  • + 1 author

18 November 2022

MicroRNAs (miRNAs) are key regulators involved in the myogenic process in skeletal muscles. miR-708-5p plays an important role in various biochemical and physiological processes, but its function in skeletal myogenesis remain unclear. In this study,...

  • Article
  • Open Access
27 Citations
5,899 Views
15 Pages

Transcriptome Analysis Reveals Long Intergenic Noncoding RNAs Contributed to Growth and Meat Quality Differences between Yorkshire and Wannanhua Pig

  • Cheng Zou,
  • Sha Li,
  • Lulu Deng,
  • Yang Guan,
  • Dake Chen,
  • Xiongkun Yuan,
  • Tianrui Xia,
  • Xinglin He,
  • Yawei Shan and
  • Changchun Li

18 August 2017

There are major differences between Yorkshire (lean-type) and Wannanhua pig (fat-type) in terms of growth performance and meat quality. Long intergenic noncoding RNAs (lincRNAs) are a class of regulators that are involved in numerous biological proce...

  • Feature Paper
  • Article
  • Open Access
2 Citations
1,908 Views
16 Pages

21 October 2024

This study identified the effects of substituting fishmeal (FM) with soy protein concentrate (SPC) supplemented with lysine and methionine in the olive flounder (Paralichthys olivaceus) diet on the expression of genes related to growth, stress, immun...

  • Article
  • Open Access
5 Citations
2,575 Views
14 Pages

6 August 2024

The present research examined the impact of L-glutamic acid (Glu) supplementation on the growth performance, muscle composition, gene expression correlated with muscle growth, and intestinal health of largemouth bass. There were 525 fish in total, wh...

  • Article
  • Open Access
1 Citations
1,786 Views
22 Pages

19 December 2024

Numerous studies have explored alternative protein sources to fishmeal (FM) to enhance fish diets, yet limited research exists on their effects on maturation. This study assessed the impact of replacing FM with soy protein concentrate (SPC) supplemen...

  • Article
  • Open Access
5 Citations
2,203 Views
19 Pages

20 July 2024

This study aimed to evaluate the impact of substituting a portion of feed with Tenebrio molitor (TM) and Elodea nuttallii (EN) on crayfish culture. A total of 270 crayfish (5.1 ± 0.4 g) were fed three different diet combinations (A: 100% feed;...

  • Article
  • Open Access
3 Citations
2,565 Views
13 Pages

5 February 2024

Growth is a fundamental aspect of aquaculture breeding programs, pivotal for successful cultivation. Understanding the mechanisms that govern growth and development differences across various stages can significantly boost seedling production of econ...

  • Article
  • Open Access
527 Views
14 Pages

12 November 2025

Hydrogen-rich water (HRW) is known for its antioxidant, anti-inflammatory, and growth-enhancing properties. However, research on its effects on mandarin fish (Siniperca chuatsi) is limited. This study aimed to explore the effects of HRW on the growth...

  • Article
  • Open Access
1 Citations
2,649 Views
14 Pages

28 February 2024

Genetic composition plays a crucial role in the growth rate of species, and transcriptomics provides a potent tool for studying genetic aspects of growth. We explored the growth rates and transcriptomes of the Cyprinids G. przewalskii (GP) and G. eck...

  • Article
  • Open Access
877 Views
14 Pages

LvSlc12A2 Is a Negative Growth Regulator in Whiteleg Shrimp, Litopenaeus vannamei

  • Panpan Niu,
  • Shanshan Jiang,
  • Mianyu Liu,
  • Siyu Chen,
  • Jie Kong,
  • Sheng Luan,
  • Xianhong Meng,
  • Qun Xing,
  • Qifan Zeng and
  • Huan Gao
  • + 1 author

22 August 2025

Litopenaeus vannamei, commonly known as the Pacific white shrimp, is one of the most economically significant species in global aquaculture, valued for its rapid growth and adaptability. However, the mechanisms regulating its growth, especially under...

  • Article
  • Open Access
2 Citations
1,787 Views
14 Pages

Genome-Wide Scans for Selection Signatures in Haimen Goats Reveal Candidate Genes Associated with Growth Traits

  • Zhen Zhang,
  • Jiafeng Lu,
  • Yifei Wang,
  • Zhipeng Liu,
  • Dongxu Li,
  • Kaiping Deng,
  • Guomin Zhang,
  • Bingru Zhao,
  • Peihua You and
  • Ziyu Wang
  • + 2 authors

7 January 2025

Understanding the genetic characteristics of indigenous goat breeds is vital for their conservation and breeding. Haimen goats, native to China’s Yangtze River Delta, possess distinctive traits such as white hair, moderate growth rate, high-qua...

  • Article
  • Open Access
119 Views
15 Pages

RNAi Identified the Potential Functions of Actin-like Protein in the Growth Performance of Macrobrachium nipponense

  • Shubo Jin,
  • Jinyu Lin,
  • Hongtuo Fu,
  • Yiwei Xiong,
  • Hui Qiao,
  • Wenyi Zhang and
  • Sufei Jiang

Macrobrachium nipponense is an important commercial freshwater prawn species in China. Since larger individuals command higher market value, there is a pressing need to identify growth-related genes and single-nucleotide polymorphisms (SNPs) to facil...

  • Article
  • Open Access
62 Citations
5,898 Views
17 Pages

27 January 2023

This work aims to determine the impact of dietary supplementation of polysaccharide, extracted from brown seaweeds Sargassum dentifolium on growth indices, feed utilization, biochemical compositions, microbial abundance, expressions of growth and imm...

  • Article
  • Open Access
13 Citations
4,037 Views
14 Pages

Evaluation of an Innovative and Sustainable Pre-Commercial Compound as Replacement of Fish Meal in Diets for Rainbow Trout during Pre-Fattening Phase: Effects on Growth Performances, Haematological Parameters and Fillet Quality Traits

  • Ümit Acar,
  • Alessia Giannetto,
  • Daniela Giannetto,
  • Osman Sabri Kesbiç,
  • Sevdan Yılmaz,
  • Alessandro Romano,
  • Rifat Tezel,
  • Ali Türker,
  • Kenan Güllü and
  • Francesco Fazio

14 December 2021

The aim of the study was to determine the potential and sustainable use of pre-commercial product ITTINSECT™ APS V1 as a major protein source in rainbow trout (Oncorhynchus mykiss) diets. A 60-day feeding experiment was conducted to potentially...

  • Article
  • Open Access
3 Citations
2,347 Views
11 Pages

Somatostatin Receptor Gene Functions in Growth Regulation in Bivalve Scallop and Clam

  • Xiangchao Zhang,
  • Yuli Niu,
  • Can Gao,
  • Lingling Kong,
  • Zujing Yang,
  • Lirong Chang,
  • Xiangfu Kong,
  • Zhenmin Bao and
  • Xiaoli Hu

Bivalves hold an important role in marine aquaculture and the identification of growth-related genes in bivalves could contribute to a better understanding of the mechanism governing their growth, which may benefit high-yielding bivalve breeding. Som...

  • Review
  • Open Access
905 Views
24 Pages

5 November 2025

A central challenge in functional genomics is understanding the difference between correlative transcriptomic observations and definitive causal understanding of gene function in vivo. Poultry skeletal muscle, a system of significant agricultural and...

  • Article
  • Open Access
10 Citations
4,743 Views
16 Pages

Nutritional Components, Biochemical Characteristics, Enzyme Activities, and Growth Differences of Five Freshwater Fish Species?

  • Xiaona Jiang,
  • Yan Li,
  • Jingwen Tian,
  • Chitao Li,
  • Yanlong Ge,
  • Xuesong Hu,
  • Lei Cheng,
  • Xiaodan Shi,
  • Lianyu Shi and
  • Zhiying Jia

13 October 2022

Common carp (Cyprinus carpio) is an economically important fish worldwide, with many of its species bred for consumption. However, there are few reports on the comprehensive comparative analysis of the muscle nutritional quality and stress resistance...

  • Article
  • Open Access
48 Citations
7,675 Views
14 Pages

5 January 2021

The present study evaluated the effect of three feeding methods (dry feed, wet feed or wet feed fermented with Bacillus licheniformis) on the growth performance, intestinal histomorphometry and gene expression of the lipid metabolism- and growth-rela...

  • Article
  • Open Access
11 Citations
3,924 Views
22 Pages

This study aims to examine the effects of the mixture of Bacillus cereus G1–11 and Exiguobacterium acetylicum G1–33, isolated from the gut of hybrid groupers (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂), on the host....

  • Article
  • Open Access
819 Views
16 Pages

Genetic Effects of Chicken Pre-miR-3528 SNP on Growth Performance, Meat Quality Traits, and Serum Enzyme Activities

  • Jianzhou Shi,
  • Jinbing Zhao,
  • Bingxue Dong,
  • Na Li,
  • Lunguang Yao and
  • Guirong Sun

6 August 2025

The aim was to investigate the genetic effects of a SNP located in the precursor region of gga-miR-3528. (1) Single-nucleotide polymorphisms within precursor regions of microRNAs play crucial biological roles. (2) Utilizing a Gushi–Anka F2 reso...

  • Article
  • Open Access
11 Citations
2,617 Views
18 Pages

19 September 2023

This study was designed to investigate the effects of enzymatically hydrolyzed poultry by-products (EHPB) on the growth and muscle quality of largemouth bass. Different concentrations of EHPB (0.00, 3.10, 6.20, 9.30, and 12.40%) were added to replace...

  • Article
  • Open Access
6 Citations
2,278 Views
18 Pages

Multiple Tissues Transcriptome of Zig-Zag Eel (Mastacembelus armatus) with Different Growth Rates

  • Jinlin Yang,
  • Baoyue Lu,
  • Zhide Yu,
  • Linan Zhang,
  • Yiman Chen,
  • Zihui Chen,
  • Chong Han and
  • Hu Shu

12 January 2024

In order to explore the main regulatory genes and related pathways of growth traits, transcriptome sequencing was first performed on the brain, liver, and muscle tissues of 3-month-old M. armatus with different growth rates. By comparative transcript...

  • Article
  • Open Access
27 Citations
8,482 Views
12 Pages

Effective MSTN Gene Knockout by AdV-Delivered CRISPR/Cas9 in Postnatal Chick Leg Muscle

  • Ke Xu,
  • Cheng Xiao Han,
  • Hao Zhou,
  • Jin Mei Ding,
  • Zhong Xu,
  • Ling Yu Yang,
  • Chuan He,
  • Fisayo Akinyemi,
  • Yu Ming Zheng and
  • He Meng
  • + 2 authors

Muscle growth and development are important aspects of chicken meat production, but the underlying regulatory mechanisms remain unclear and need further exploration. CRISPR has been used for gene editing to study gene function in mice, but less has b...

  • Article
  • Open Access
16 Citations
4,961 Views
13 Pages

Transcriptome Analysis of Differentially Expressed mRNA Related to Pigeon Muscle Development

  • Hao Ding,
  • Yueyue Lin,
  • Tao Zhang,
  • Lan Chen,
  • Genxi Zhang,
  • Jinyu Wang,
  • Kaizhou Xie and
  • Guojun Dai

5 August 2021

The mechanisms behind the gene expression and regulation that modulate the development and growth of pigeon skeletal muscle remain largely unknown. In this study, we performed gene expression analysis on skeletal muscle samples at different developme...

  • Article
  • Open Access
24 Citations
4,133 Views
39 Pages

20 October 2020

In China, the production for duck meat is second only to that of chicken, and the demand for duck meat is also increasing. However, there is still unclear on the internal mechanism of regulating skeletal muscle growth and development in duck. This st...

  • Article
  • Open Access
7 Citations
2,912 Views
17 Pages

Dynamic Changes in the Global Transcriptome of Postnatal Skeletal Muscle in Different Sheep

  • Yue Ai,
  • Yaning Zhu,
  • Linli Wang,
  • Xiaosheng Zhang,
  • Jinlong Zhang,
  • Xianlei Long,
  • Qingyi Gu and
  • Hongbing Han

20 June 2023

Sheep growth performance, mainly skeletal muscle growth, provides direct economic benefits to the animal husbandry industry. However, the underlying genetic mechanisms of different breeds remain unclear. We found that the cross-sectional area (CSA) o...

  • Article
  • Open Access
8 Citations
2,570 Views
18 Pages

1 June 2023

Skeletal muscle growth and development from embryo to adult consists of a series of carefully regulated changes in gene expression. This study aimed to identify candidate genes involved in Haiyang Yellow Chickens’ growth and to understand the r...

  • Article
  • Open Access
20 Citations
9,834 Views
19 Pages

9 April 2015

Myostatin (MSTN), a member of the transforming growth factor-β superfamily, plays a crucial negative role in muscle growth. MSTN mutations or inhibitions can dramatically increase muscle mass in most mammal species. Previously, we generated a transge...

  • Article
  • Open Access
23 Citations
5,962 Views
16 Pages

7 January 2022

Recently, extracellular vesicle (EV)-mediated cell differentiation has gained attention in developmental biology due to genetic exchange between donor cells and recipient cells via transfer of mRNA and miRNA. EVs, also known as exosomes, play a role...

  • Article
  • Open Access
1 Citations
809 Views
13 Pages

Cloning and Transcriptional Activity Analysis of the Bovine CDH11 Gene Promoter: Transcription Factors Sp1 and GR Regulate Bovine CDH11 Expression

  • Zhanxin Liu,
  • Yanbin Bai,
  • Zongchang Chen,
  • Yanmei Niu,
  • Xue Jia,
  • Liang Li,
  • Xiaolan Zhang,
  • Binggang Shi,
  • Zhidong Zhao and
  • Fangfang Zhao
  • + 5 authors

25 April 2025

Growth rate of bovine skeletal muscle has a major impact on beef yield. Cadherin-11 (CDH11) was found to be a potential candidate gene for growth and development in beef cattle. This study confirmed the high expression of CDH11 in bovine longissimus...

  • Article
  • Open Access
8 Citations
2,870 Views
14 Pages

3 January 2023

The Duroc pig originated in the United States and is a typical lean-meat pig. The breed grows fast, and the body size is large, but the meat quality is poor. The Luchuan pig is one of eight excellent local breeds in China; it has tender meat but is s...

  • Article
  • Open Access
6 Citations
3,442 Views
15 Pages

Effect of Zbed6 Single-Allele Knockout on the Growth and Development of Skeletal Muscle in Mice

  • Ling Liu,
  • Shengnan Wang,
  • Wenjie Tian,
  • Cheng Xu,
  • Chengjie Wei,
  • Kai Cui,
  • Lin Jiang and
  • Dandan Wang

17 February 2023

ZBED6, a key transcription factor, plays an important role in skeletal muscle and organ growth. ZBED6 knockout (ZBED6−/−) leads to the upregulation of IGF2 in pig and mice muscle, thereby increasing muscle mass. However, the effects and m...

  • Article
  • Open Access
24 Citations
3,816 Views
20 Pages

16 March 2021

Skeletal muscle, accounting for approximately 50% of body weight, is the largest and most important tissue. In this study, the gene expression profiles and pathways in skeletal muscle of Pekin duck were investigated and compared at embryonic day 17,...

  • Review
  • Open Access
208 Citations
19,577 Views
25 Pages

Key Genes Regulating Skeletal Muscle Development and Growth in Farm Animals

  • Mohammadreza Mohammadabadi,
  • Farhad Bordbar,
  • Just Jensen,
  • Min Du and
  • Wei Guo

16 March 2021

Farm-animal species play crucial roles in satisfying demands for meat on a global scale, and they are genetically being developed to enhance the efficiency of meat production. In particular, one of the important breeders’ aims is to increase skeletal...

  • Article
  • Open Access
4 Citations
1,899 Views
18 Pages

22 August 2024

With the continuous improvement in living standards, people’s demand for high-quality meat is increasing. Ningxiang pig has delicious meat of high nutritional value, and is loved by consumers. However, its slow growth and low meat yield serious...

  • Article
  • Open Access
38 Citations
6,697 Views
20 Pages

Genome-Wide Analysis Reveals Extensive Changes in LncRNAs during Skeletal Muscle Development in Hu Sheep

  • Caifang Ren,
  • Mingtian Deng,
  • Yixuan Fan,
  • Hua Yang,
  • Guomin Zhang,
  • Xu Feng,
  • Fengzhe Li,
  • Dan Wang,
  • Feng Wang and
  • Yanli Zhang

1 August 2017

As an important type of noncoding RNA molecules, long non-coding RNAs (lncRNAs) act as versatile players in various biological processes. However, little is known about lncRNA regulators during sheep muscle growth. To explore functional lncRNAs durin...

  • Article
  • Open Access
51 Citations
8,547 Views
21 Pages

Deep Sequencing Analysis of miRNA Expression in Breast Muscle of Fast-Growing and Slow-Growing Broilers

  • Hongjia Ouyang,
  • Xiaomei He,
  • Guihuan Li,
  • Haiping Xu,
  • Xinzheng Jia,
  • Qinghua Nie and
  • Xiquan Zhang

17 July 2015

Growth performance is an important economic trait in chicken. MicroRNAs (miRNAs) have been shown to play important roles in various biological processes, but their functions in chicken growth are not yet clear. To investigate the function of miRNAs...

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