Carbon dots (CDs) have attracted widespread attention in recent years due to their synthetic simplicity, biocompatibility, and unique photoluminescent behavior. In this work, water-soluble silicon–carbon dots (SiCDs) were synthesized, and their...
Magnetic nanoparticles (MNPs) that exhibit high specific loss power (SLP) at lower metal content are highly desirable for hyperthermia applications. The conventional co-precipitation process has been widely employed for the synthesis of magnetic nano...
The magnetic nanoparticles (MNPs) with decreasing heating efficiency (characterized by specific loss power, SLP) with temperature increase, especially around the Curie temperature (TC), are expected to realize the self-regulated temperature hyperther...
The clinical translation of magnetic hyperthermia (MH) needs magnetic nanoparticles (MNPs) with enhanced heating properties and good biocompatibility. Many studies were devoted lately to the increase in the heating power of iron oxide MNPs by doping...
We report the synthesis of magnetite nanoparticles (IOMNPs) using the polyol method performed at elevated temperature (300 °C) and high pressure. The ferromagnetic polyhedral IOMNPs exhibited high saturation magnetizations at room temperature (83...
Spinel ferrite nanoparticles represent a class of magnetic nanoparticles (MNPs) with enormous potential in magnetic hyperthermia. In this study, we investigated the magnetic and heating properties of spinel soft NiFe2O4, MnFe2O4, and hard CoFe2O4 MNP...
Magnetic hyperthermia is a promising cancer treatment technique that relies on Néel and Brownian relaxation mechanisms to heat superparamagnetic nanoparticles injected into tumor sites. Under low-frequency magnetic fields, nanoparticles genera...
Manganese and zinc ferrite magnetic nanoparticles (MNPs) were successfully synthesized
using the polyol method in ethylene glycol and were found to have high saturation magnetization
values (90–95 emu/g at 4 K) when formed by ~30-nm crystallites...
Carbon-encapsulated iron nanoparticles (Fe@C) with a mean diameter of 15 nm have been synthesized using evaporation–condensation flow–levitation method by the direct iron-carbon gas-phase reaction at high temperatures. Further, Fe@C were...
Magnetic nanoparticles became increasingly interesting in recent years as a result of their tailorable size-dependent properties, which enable their use in a wide range of applications. One of their emerging applications is biomedicine; in particular...
This study is an attempt to produce gadolinium-doped iron oxide nanoparticles for the purpose of utilization in magnetic fluid hyperthermia (MFH). Six gadolinium-doped iron oxide samples with varying gadolinium contents (
Magnetic nanoparticles can generate heat when exposed to an alternating magnetic field. Their heating efficacy is governed by their magnetic properties that are in turn determined by their composition, size and morphology. Thus far, iron oxides (e.g....
The study presented in this work consists of two parts: The first part is the synthesis of Graphene oxide-Fe3O4 nanocomposites by a mechanochemical method which, is a mechanical process that is likely to yield extremely heterogeneous particles. The s...
Superparamagnetic ZnxFe3−xO4 magnetic nanoparticles (0 ≤ x < 0.5) with spherical shapes of 16 nm average diameter and different zinc doping level have been successfully synthesized by co-precipitation method. The homogeneous zinc substitu...
In this study, the role of blood perfusion in modulating the thermal response of tumors during magnetic nanoparticle hyperthermia was investigated through computational modeling. The thermal dissipation of 15 nm magnetite nanoparticles was estimated...
Magnetic structures exhibiting large magnetic moments are sought after in theranostic approaches that combine magnetic hyperthermia treatment (MH) and diagnostic magnetic resonance imaging in oncology, since they offer an enhanced magnetic response t...
Magnetic fluid hyperthermia has gained much attention in recent years due to its potential in cancer treatment. Magnetic fluid is a colloidal liquid made of nanoscale magnetic particles suspended in a carrier fluid. The properties of a commercial mag...
In the original publication [...]
Magnetic hyperthermia is a technique that describes the heating of material through an external magnetic field. Classic hyperthermia is a medical condition where the human body overheats, being usually triggered by a heat stroke, which can lead to se...
Hyperthermia, though by itself generally non-curative for cancer, can significantly increase the efficacy of radiation therapy, as demonstrated by in vitro, in vivo, and clinical results. Its limited use in the clinic is mainly due to various practic...
Iron oxide nanoparticle-based hyperthermia is an emerging field in cancer treatment. The hyperthermia is primarily achieved by two differing methods: magnetic fluid hyperthermia and photothermal therapy. In magnetic fluid hyperthermia, the iron oxide...
Magnetic hyperthermia (MH), proposed by R. K. Gilchrist in the middle of the last century as local hyperthermia, has nowadays become a recognized method for minimally invasive treatment of oncological diseases in combination with chemotherapy (ChT) a...
Hyperthermia therapy is a medical treatment based on the exposition of body tissue to slightly higher temperatures than physiological (i.e., between 41 and 46 °C) to damage and kill cancer cells or to make them more susceptible to the effects of radi...
Localized magnetic hyperthermia using magnetic nanoparticles (MNPs) under the application of small magnetic fields is a promising tool for treating small or deep-seated tumors. For this method to be applicable, the amount of MNPs used should be mini...
The design of novel nanomaterials that can be used as multifunctional platforms allowing the combination of therapies is gaining increased interest. Moreover, if this nanomaterial is intended for a targeted drug delivery, the use of several guidance...
The clinical implementation of magnetic hyperthermia has experienced little progress since the first clinical trial was completed in 2005. Some of the hurdles to overcome are the reliable production of magnetic nanoparticles with controlled propertie...
Magnetic hyperthermia can complement traditional cancer treatments by exploiting the greater heat sensitivity of tumor cells. This approach allows for localized action, increasing its therapeutic effectiveness. In this study, MCF-7 breast cancer cell...
Superparamagnetic iron oxide nanoparticles (SPIONs) have high saturation magnetization and are promising candidates for hyperthermia. They may act as magnetic heating agents when subjected to magnetic field in nano-based hyperthermia. In this work, c...
Doxorubicin is a cytotoxic drug used for the treatment of many cancer types. However, its significant dose-related adverse effects including cardiotoxicity may hamper its efficiency. Moreover, the multidrug resistance that appears during treatments l...
Dextran-coated magnetic nanoparticles are promising biocompatible agents in various biomedical applications, including hyperthermia and magnetic resonance imaging (MRI). However, the influence of dextran molecular weight on the physical properties of...
In this study, silica-encapsulated gadolinium was doped in lanthanum strontium manganite nanoparticles (NPs) with different concentrations using the citrate–gel auto-combustion method. We focused on tuning the Curie temperature and enhancing th...
Ultrasound hyperthermia is a medical treatment used to increase temperature of tissues. It can be used independently or as a supportive method for an anticancer treatment. The therapeutic efficacy of focused ultrasound hyperthermia can be improved us...
Magnetic iron oxide nanoparticles (MNPs) have been developed and applied for a broad range of biomedical applications, such as diagnostic imaging, magnetic fluid hyperthermia, targeted drug delivery, gene therapy and tissue repair. As one key element...
The cancer therapy with the lowest possible toxicity is today an issue that raises major difficulties in treating malignant tumors because chemo- and radiotherapy currently used in this field have a high degree of toxicity and in many cases are ineff...
Integrating hyperthermia with conventional cancer therapies shows promise in improving treatment efficacy while mitigating their side effects. Nanotechnology-based hyperthermia, particularly using superparamagnetic iron oxide nanoparticles (SPIONs),...
In this work, complex studies of the structure and magnetic properties of SrFe12−xInxO19 powders obtained by the mechanochemical and citrate methods were carried out. The solubility of In in strontium hexaferrite SrFe₁₂O₁̀...
The number of cancer patients is rapidly increasing worldwide. Among the leading causes of human death, cancer can be regarded as one of the major threats to humans. Although many new cancer treatment procedures such as chemotherapy, radiotherapy, an...
Heterostructured magnetic nanoparticles show great potential for numerous applications in biomedicine due to their ability to express multiple functionalities in a single structure. Magnetic properties are generally determined by the morphological ch...
Several developments have recently emerged for core-shell magnetic nanomaterials, indicating that they are suitable materials for biomedical applications. Their usage in hyperthermia and drug delivery applications has escalated since the use of shell...
Iron oxide nanoparticles are commonly used in many medical applications as they can be easily modified, have a high surface-to-volume ratio, and are biocompatible and biodegradable. This study was performed to synthesize nanoparticles designed for mu...
The aim of this study was to develop an innovative, dual-stimuli-responsive smart hydrogel local drug delivery system (LDDS), potentially useful as an injectable simultaneous chemotherapy and magnetic hyperthermia (MHT) antitumor treatment device. Th...
Hyperthermia, an alternative medical approach aiming at locally increasing the temperature of a tumor, can cause the “death” of cancer cells or the sensitization of them to chemotherapeutic drugs and radiation. In contrast with the conven...
Currently, one of the main causes of death in the world is cancer; therefore, it is urgent to obtain a precocious diagnosis, as well as boost research and development of new potential treatments, which should be more efficient and much less invasive...
Background: Hyperthermia (HT) therapy still remains relatively unknown, in terms of both its biological and therapeutic effects. This work aims to analyze the effects of exposure to HT, such as that required in anti-tumor magnetic hyperthermia therap...
Recently, in-vitro studies of magnetic nanoparticle (MNP) hyperthermia have attracted significant attention because of the severity of this cancer therapy for in-vivo culture. Accurate temperature evaluation is one of the key challenges of MNP hypert...
The development of nanomedicine involves complex nanomaterial research involving magnetic nanomaterials and their use in magnetic hyperthermia. The selection of the optimal treatment strategies is time-consuming, expensive, unpredictable, and not con...
Background/Objectives: The unique properties of iron oxide nanoparticles have attracted significant interest within the biomedical community, particularly for magnetic hyperthermia applications. Various synthesis methods have been developed to optimi...
Manganese-zinc ferrite (MZF) is known as high-performance magnetic material and has been used in many fields and development. In the biomedical applications, the biocompatible MZF formulation attracted much attention. In this study, water-soluble amp...
The use of perovskite manganite nanoparticles in magnetic hyperthermia has attracted significant attention due to their tunable magnetic properties and high specific absorption rate (SAR). In this work, we present a combined experimental and theoreti...
Cancer is considered today as a prevalent research direction due to the fact that, by 2050, more than 30 million cases will occur, followed by about 19 million deaths. It is expected that scholars will search for new, innovative, and localized therap...
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