The modern orthopaedic implants for applications in hips, knees, shoulders, and spines are composed of hard metal alloys or ceramics and a tribological sub-component that is made of soft materials, with good frictional properties—e.g., UHMWPE (...
The design and manufacturing of medical implants constitutes an active and highly important field of research, both from a medical and an engineering point of view. From an engineering aspect, the machining of implants is undoubtedly challenging due...
All neural information systems (NIS) rely on sensing neural activity to supply commands and control signals for computers, machines and a variety of prosthetic devices. Invasive systems achieve a high signal-to-noise ratio (SNR) by eliminating the vo...
There is a growing interest in the use of electrocorticographic (ECoG) signals in brain–machine interfaces (BMIs). However, there is still a lack of studies involving the long-term evaluation of the tissue response related to electrode implanta...
Sapphire crystals, owing to their outstanding mechanical and optical properties, which are widely used in advanced optics, microelectronic devices, and medical instruments. The manufacturing precision of sapphire optical components critically affects...
It is necessary to know the manufacturer and model of a previously implanted shoulder prosthesis before performing Total Shoulder Arthroplasty operations, which may need to be performed repeatedly in accordance with the need for repair or replacement...
Background/Objectives: Cochlear implantation is an advantageous procedure for individuals with severe to profound hearing loss in many aspects related to auditory performance, social communication and quality of life. As machine learning applications...
Background: To prevent excessive compression of the cortical layer, which can lead to marginal bone loss, various companies have introduced specialized drills. However, these drills often lack the necessary precision, as the operator’s hand may...
An experimental comparative study of the biomechanical behavior of commonly used orthopedic implants for tibial plateau fractures was carried out. An artificial bone model Synbone1110 was used and a Schatzker V type tibial plateau fracture was create...
Background: The aim of the present multi-center split-mouth randomized control trial was to investigate the effect on peri-implant tissue of abutment with chromium nitride/ niobium nitride (CrN/NbN) coatings (superlattice) compared to traditional mac...
Objective: The primary objective of the present retrospective clinical study was to evaluate and compare the clinical performance presented by castable abutments developed for the MT system versus intermediate machined abutments, specifically regardi...
Background: Current guideline-based implantable cardioverter-defibrillator (ICD) implants fail to meet the demands for precision medicine. Machine learning (ML) designed for survival analysis might facilitate personalized risk stratification. We aime...
Background/Objectives: Cochlear implantation is the most widely used treatment option for patients with severe to profound hearing loss. Despite being a relatively standardized surgical procedure, cochlear implant (CI) outcomes vary considerably amon...
Background/Objectives: Cochlear implantation (CI) significantly enhances speech perception and quality of life in patients with severe-to-profound sensorineural hearing loss, yet outcomes vary substantially. Accurate preoperative prediction of CI out...
Background: Machine learning (ML) techniques have been recently proposed as a solution for aiding in the prevention and diagnosis of microbiome-related diseases. Here, we applied auto-ML approaches on real-case metagenomic datasets from saliva and su...
Peri-implantitis (PI) is a chronic inflammatory disease that ultimately leads to the dysfunction and loss of implants with established osseointegration. Ferroptosis has been implicated in the progression of PI, but its precise mechanisms remain uncle...
Cochlear implantation is the common treatment for severe to profound sensorineural hearing loss if there is no benefit from hearing aids. Measuring the electrode impedance along the electrode array at different time points after surgery is crucial in...
Current prognostic risk scores for transcatheter aortic valve implantation (TAVI) do not benefit yet from modern machine learning techniques, which can improve risk stratification of one-year mortality of patients before TAVI. Despite the advancement...
Background/Objectives: Speech produced by individuals with hearing loss differs notably from that of normal-hearing (NH) individuals. Although cochlear implants (CIs) provide sufficient auditory input to support speech acquisition and control, there...
Crest module can be defined as the portion of a two-piece implant designed to retain the prosthetic components and to allows the maintenance of the peri-implant tissues in the transition zone. Aim: To evaluate the three-year after loading clinical an...
Background: Dental implant abutment screw loosening is an increasingly common problem, as evidenced by multiple studies that have investigated its causes. The objective of this study was to compare the screw loosening torque values before and after c...
Collagen implants in neurosurgery are widely used due to their biocompatibility, biodegradability, and ability to support tissue regeneration, but their mechanical properties, such as low tensile strength and susceptibility to enzymatic degradation,...
Surface modification is given vital importance in the biomedical industry to cope with surface tissue growth problems. Conventionally, basic surface treatment methods are used which include physical and chemical deposition. The major drawbacks associ...
This study presents a multi-objective optimization framework for designing cylindrical triply periodic minimal surface (TPMS) lattices tailored for bone implant applications. Using an artificial neural network (ANN) as a surrogate model trained on si...
Background/Objectives: Evidence from transcriptomic and histopathologic studies has revealed that peri-implantitis lesions are characterized by deeper inflammatory infiltration, increased immune cell accumulation, and distinctive molecular signatures...
As the name implies, patient-specific latticed hip implants vary in design depending on the properties required by the patient to serve as a valid suitable organ. Unit cells are typically built based on a 3D design of beams, and the properties of uni...
Soft material-enabled electronics offer distinct advantages over conventional rigid and bulky devices for numerous wearable and implantable applications. Soft materials allow for seamless integration with skin and tissues due to the enhanced mechanic...
The aim of this work is to incorporate lanthanide-cored upconversion nanoparticles (UCNP) into the surface of microengineered biomedical implants to create a spatially controlled and optically releasable model drug delivery device in an integrated fa...
The production of biocompatible medical implants is accompanied by technological and time costs. As a result, to be used in the human body, such a product must be of the highest quality. Assessing the quality of biomedical implants made of titanium a...
An end-fire radiating implantable antenna with a small footprint and broadband operation at the frequency range of 3–5 GHz is proposed for high-data-rate wireless communication in a brain–machine interface. The proposed Vivaldi antenna wa...
Currently, treatment of diabetes and associated obesity involves Roux-en-Y gastric bypass or sleeve gastrectomy to reduce the absorption of nutrients from the intestine to achieve blood glucose control. However, the surgical procedure and subsequent...
This study evaluates the potential of erbium, chromium-doped:yttrium, scandium, gallium, and garnet (Er,Cr:YSGG) laser irradiation to modify the titanium surface for optimal seeding of fibroblasts and osteoblasts in the treatment of peri-implantitis....
Implantable bioelectronics hold tremendous potential in the field of healthcare, yet the performance of these systems heavily relies on the interfaces between artificial machines and living tissues. In this paper, we discuss the recent developments o...
To prevent pedicle screw implant failure, a diagnostic technique that allows surgeons to evaluate implant stability easily, quickly, and quantitatively in clinical orthopedic situations is required. This study aimed to predict the insertion torque eq...
Emerging artificial intelligence (AI) and robotic surgical technologies have the potential to influence digital implant dentistry substantially. As a narrative review, and building on the foundations outlined in Part I, which described current digita...
The recently growing progress in neuroscience research and relevant achievements, as well as advancements in the fabrication process, have increased the demand for neural interfacing systems. Brain–machine interfaces (BMIs) have been revealed t...
Cardiac implantable electronic devices (CIEDs) such as pacemakers, implantable cardioverter-defibrillators (ICDs), and cardiac resynchronisation therapy (CRT) devices are generating unprecedented volumes of data in both inpatient and remote settings....
Background: Sudden cardiac death (SCD) remains a major cause of cardiovascular mortality. Implantable cardioverter-defibrillators (ICDs) reduce arrhythmic mortality, but current selection based largely on left ventricular ejection fraction (LVEF) lac...
Total Shoulder Arthroplasty (TSA) is the process of replacing the damaged ball and socket joint in the shoulder with a prosthesis made with polyethylene and metal components. After this procedure, intervention may be required as a result of damage to...
Biocompatible materials with excellent mechanical properties as well as sophisticated surface morphology and chemistry are required to satisfy the requirements of modern dental implantology. In the study described in this article, an industrial-grade...
Current prognostic risk scores in cardiac surgery do not benefit yet from machine learning (ML). This research aims to create a machine learning model to predict one-year mortality of a patient after transcatheter aortic valve implantation (TAVI). We...
Although cochlear implants work well for people with hearing impairment in quiet conditions, it is well-known that they are not as effective in noisy environments. Noise reduction algorithms based on machine learning allied with appropriate speech fe...
Sudden cardiac death (SCD) remains a major clinical challenge, with implantable cardioverter-defibrillators (ICDs) serving as the primary preventive intervention. Current patient selection guidelines rely on limited and imperfect risk markers. This s...
Background: Cochlear implants (CIs) serve diverse populations with hearing loss, but patients with single-sided deafness (SSD) often show lower post-implantation usage and satisfaction than bilateral CI users. This disparity may stem from their norma...
Window of implantation (WOI) genes have been comprehensively identified at the single cell level. DNA methylation changes in cervical secretions are associated with in vitro fertilization embryo transfer (IVF-ET) outcomes. Using a machine learning (M...
A new, simple machine was developed to address a long-standing challenge in biomedical and mechanical engineering: how to enhance the primary stability and long-term integration of screws and implants in low-density or heterogeneous materials, such a...
Ultraviolet (UV) photofunctionalization has been suggested as an effective method to enhance the osseointegration of titanium surface. In this study, machined surface treated with UV light (M + UV) was compared to sandblasted, large-grit, acid-etched...
The increasing prevalence of cardiovascular complications in cancer patients due to cardiotoxic treatments has necessitated advanced monitoring and predictive solutions. Cardio-oncology is an evolving interdisciplinary field that addresses these chal...
Evaluation of the initial stability of implants is essential to reduce the number of implant failures of pedicle screws after orthopedic surgeries. Laser resonance frequency analysis (L-RFA) has been recently proposed as a viable diagnostic scheme in...
PDMS (polydimethylsiloxane) is an important soft biocompatible material, which has various applications such as an implantable neural interface, a microfluidic chip, a wearable brain–computer interface, etc. However, the selective removal of th...
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