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18 pages, 7881 KB  
Article
Bridging Targeting Precision and Oncologic Safety: Localization Accuracy for Margin Adequacy in Cone-Beam Computed Tomography-Guided Pulmonary Nodule Resection
by Yu-Hsiang Wang, Hsu-Chih Huang, Chih-Yi Chen, Jiun-Yi Hsia, Guo-Zhi Wang, Ming-Chih Chou and Frank Cheau-Feng Lin
Cancers 2026, 18(14), 2356; https://doi.org/10.3390/cancers18142356 - 21 Jul 2026
Viewed by 410
Abstract
Background/Objectives: Ground-glass pulmonary nodules are often nonpalpable and not visible during thoracoscopic surgery, making accurate localization important for achieving adequate pathological margins. However, no clinically validated localization-error threshold has been established. We evaluated the association between Dmn and pathological margin adequacy after image-guided [...] Read more.
Background/Objectives: Ground-glass pulmonary nodules are often nonpalpable and not visible during thoracoscopic surgery, making accurate localization important for achieving adequate pathological margins. However, no clinically validated localization-error threshold has been established. We evaluated the association between Dmn and pathological margin adequacy after image-guided thoracoscopic pulmonary nodule resection and sought to identify a clinically relevant localization-accuracy threshold. Methods: We retrospectively reviewed 169 patients in a predefined peripheral-lesion cohort who underwent cone-beam computed tomography-guided pulmonary nodule localization using hook-wire placement or dye marking in a hybrid operating room, followed by thoracoscopic wedge resection. Dmn was defined as the shortest three-dimensional Euclidean distance from the localization needle tip to the tumor margin. Pathological margin adequacy was defined as a resection margin equal to or greater than the maximum tumor diameter. Logistic regression was used to identify predictors of pathological margin inadequacy, and receiver operating characteristic analysis was performed to determine the optimal Dmn cutoff. Results: Dmn was independently associated with pathological margin inadequacy (odds ratio, 1.617; 95% confidence interval, 1.356–1.928; p < 0.001). Receiver operating characteristic analysis yielded an area under the curve of 0.827 and an optimal Dmn cutoff of 4.90 mm, with a sensitivity of 71.0% and specificity of 94.2%. Pathological margin inadequacy occurred more frequently in patients with Dmn ≥ 4.9 mm than in those with Dmn < 4.9 mm (73.3% vs. 6.5%, p < 0.001). Conclusions: In this single-center cohort, a Dmn of approximately 4.9 mm was associated with pathological margin inadequacy after cone-beam computed tomography-guided pulmonary nodule localization and thoracoscopic wedge resection. This value may serve as a candidate intraoperative warning threshold for margin reassessment; however, prospective external validation is required before routine clinical implementation. Full article
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8 pages, 372 KB  
Proceeding Paper
AutoSignal: A Dart-Based Programming Paradigm for Automatic Component Connection via a Signal–Slot Architecture
by George Pashev and Silvia Gaftandzhieva
Eng. Proc. 2026, 150(1), 15; https://doi.org/10.3390/engproc2026150015 - 17 Jul 2026
Viewed by 663
Abstract
Managing event-driven communication in large reactive codebases remains a persistent challenge: developers routinely write repetitive wiring code that becomes difficult to trace and maintain. We present AutoSignal, a programming paradigm for the Dart ecosystem that automates component interconnection through a signal–slot architecture based [...] Read more.
Managing event-driven communication in large reactive codebases remains a persistent challenge: developers routinely write repetitive wiring code that becomes difficult to trace and maintain. We present AutoSignal, a programming paradigm for the Dart ecosystem that automates component interconnection through a signal–slot architecture based on name and data-type matching. To improve scalability and limit unintended side effects in large applications, the framework implements hierarchical namespace isolation and deterministic reactivity through topological sorting of dependency graphs. In a reference contact-management application, AutoSignal reduced connection-specific code by 47%, unintended signal propagation by 32%, and average propagation latency by 28% relative to manual wiring. The framework also integrates with Flutter through reactive UI primitives such as specialized hooks and builders. These results indicate that AutoSignal is a practical, type-aware option for building maintainable event-driven applications in the Dart/Flutter ecosystem. Full article
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24 pages, 10752 KB  
Article
Real-Time Wire Rope Inclination Detection Using YOLOv9-Based Camera–LiDAR Fusion for Overhead Cranes
by Anh-Hung Pham, Ga-Eun Jung, Xuan-Kien Mai, Byeong-Soo Go and Seok-Ju Lee
J. Mar. Sci. Eng. 2026, 14(4), 393; https://doi.org/10.3390/jmse14040393 - 20 Feb 2026
Viewed by 1122
Abstract
Safe and efficient cargo handling is essential in modern port logistics, where overhead cranes are widely used to move containers, bulk materials, and heavy equipment. Accurate real-time measurement of wire rope inclination is critical for preventing collisions, reducing load sway, and enabling autonomous [...] Read more.
Safe and efficient cargo handling is essential in modern port logistics, where overhead cranes are widely used to move containers, bulk materials, and heavy equipment. Accurate real-time measurement of wire rope inclination is critical for preventing collisions, reducing load sway, and enabling autonomous crane operation under challenging maritime conditions. This paper presents a You Only Look Once v9 (YOLOv9)-based camera–LiDAR fusion system for real-time estimation of the trolley–hook rope inclination angle in overhead cranes. A monocular industrial camera and a YOLOv9 detector provide semantic region-of-interest (ROI) masks for the trolley and hook, while a 3D LiDAR sensor, rigidly mounted and extrinsically calibrated to the camera, provides depth information. LiDAR points projected onto the image and filtered by YOLOv9 bounding boxes allow efficient extraction of safety-critical 3D geometry and reconstruction of the rope vector. Experimental results on an overhead crane testbed show that the proposed fusion estimator achieves an angle RMSE below 1 degree in dynamic swing and low-illumination scenarios, significantly outperforming a camera-only baseline (RMSE ≈ 2.11). These metrically validated results indicate that the proposed detection pipeline offers a robust foundation for intelligent crane monitoring and automation in maritime logistics and smart port operations. Full article
(This article belongs to the Section Ocean Engineering)
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11 pages, 1114 KB  
Article
Locking Plate with Cerclage Wiring Versus Hook Plate Fixation for Unstable Distal Clavicle Fractures: Is There Still a Role for Hook Plates?
by Hyun Seok Song and Hyungsuk Kim
Medicina 2025, 61(10), 1882; https://doi.org/10.3390/medicina61101882 - 21 Oct 2025
Cited by 2 | Viewed by 1827
Abstract
Background and Objectives: Hook plate fixation has been widely used for unstable distal clavicle fractures, but concerns remain regarding implant-related complications and the need for secondary removal. Locking plate fixation with supplementary cerclage wiring has been proposed as an alternative that may [...] Read more.
Background and Objectives: Hook plate fixation has been widely used for unstable distal clavicle fractures, but concerns remain regarding implant-related complications and the need for secondary removal. Locking plate fixation with supplementary cerclage wiring has been proposed as an alternative that may provide stability while reducing complications. This study compared the clinical and radiologic outcomes of locking plate fixation with cerclage wiring versus hook plate fixation. Materials and Methods: A retrospective review was performed on patients who underwent open reduction and internal fixation for unstable distal clavicle fractures (Cho’s classification type II) between 2015 and 2024. Patients with at least 6 months of follow-up were included. Two techniques were evaluated: locking plate with cerclage wiring (Group 1) and hook plate fixation (Group 2). Clinical outcomes, including complications, range of motion, and patient satisfaction, were compared at the final follow-up. Results: A total of 52 patients met the inclusion criteria: 27 in Group 1 and 25 in Group 2. The overall mean follow-up period was 13.17 ± 8.46 months. The distribution of fracture types was not significantly different between groups (p = 0.287). Complications were more frequent in Group 2 (40%), including postoperative stiffness requiring capsular release (70%), nonunion requiring revision (20%), and peri-implant fracture (10%). The overall union rate was 100% in Group 1 and 80% in Group 2. In contrast, Group 1 had only one complication (3.7%), a peri-implant fracture (p = 0.002). Shoulder range of motion at the final follow-up showed no significant difference between groups. Conclusions: Hook plate fixation was associated with a significantly higher complication rate compared with locking plate fixation with cerclage wiring. Locking plate fixation with supplementary cerclage wiring appears to be a better surgical option for unstable distal clavicle fractures. Full article
(This article belongs to the Special Issue Orthopedic Trauma: Surgical Treatment and Rehabilitation)
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14 pages, 1360 KB  
Article
Multicenter Prospective Comparative Study of Patient Radiation Doses in Localization Techniques for Small Lung Lesions
by Tomoki Nishida, Yuichi Saito, Takeshi Takata, Shizuka Morita, Ryo Takeyama, Shinya Kohmaru, Tomohiro Watanabe, Nobuo Yamaguchi, Hikaru Takahashi, Yasuyuki Kanamoto, Hiroaki Morooka, Takayuki Ibi, Yoshikane Yamauchi, Ryuta Fukai, Nobumasa Takahashi, Tetsu Kanauchi, Ikuo Kobayashi, Masafumi Kawamura and Yukinori Sakao
Cancers 2025, 17(19), 3119; https://doi.org/10.3390/cancers17193119 - 25 Sep 2025
Cited by 2 | Viewed by 1300
Abstract
Background/Objectives: Although surgeries employing cone-beam computed tomography (CBCT) for small lung lesions have been reported, the association between CBCT scan frequency and patient radiation exposure remains unclear. This study aimed to investigate patient radiation doses from CBCT during thoracic surgeries, and the patient [...] Read more.
Background/Objectives: Although surgeries employing cone-beam computed tomography (CBCT) for small lung lesions have been reported, the association between CBCT scan frequency and patient radiation exposure remains unclear. This study aimed to investigate patient radiation doses from CBCT during thoracic surgeries, and the patient radiation doses were compared with those from other preoperative marking methods. Methods: This multicenter prospective study included 81 patients who underwent surgery for small lung lesions requiring marking between January 2021 and June 2024 at three institutions. CBCT-guided surgeries involved the use of metal clips in a hybrid operating room with 1–4 scans, depending on the lesion. For other preoperative marking methods, hook-wire or virtual-assisted lung mapping (VAL-MAP) was used. Patient radiation doses were measured using wearable dosimeters at five anterior thorax sites, and the total dose was compared across methods. Results: The study included 81 patients: CBCT (n = 61), VAL-MAP (n = 10), and hook-wire (n = 10). CBCT cases were distributed as follows: single scan (n = 10), double scans (n = 34), triple scans (n = 15), and quadruple scans (n = 2). The radiation doses were 86.9 ± 61.7 mGy for hook-wire, 39.8 ± 27.5 mGy for VAL-MAP, and 11.0 ± 6.5 mGy for single-scan CBCT, 17.3 ± 7.8 mGy for double scans, 23.1 ± 14.0 mGy for triple scans, and 22.7 ± 0.1 mGy for quadruple scans. Although radiation exposure increased with more CBCT scans, performing up to triple scans resulted in significantly lower exposure compared to other methods. Conclusions: Intraoperative CBCT is a feasible and safe technique for identifying small lung lesions, providing lower radiation exposure compared to other preoperative localization methods. Full article
(This article belongs to the Special Issue Clinical Research on Thoracic Cancer)
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14 pages, 3113 KB  
Article
Development of the Biofidelic Instrumented Neck Surrogate (BINS) with Tunable Stiffness and Embedded Kinematic Sensors for Application in Static Tests and Low-Energy Impacts
by Giuseppe Zullo, Elisa Baldoin, Leonardo Marin, Andrey Koptyug and Nicola Petrone
Sensors 2025, 25(16), 4925; https://doi.org/10.3390/s25164925 - 9 Aug 2025
Cited by 1 | Viewed by 1495
Abstract
Road accidents could result in severe or fatal neck injuries. A few surrogate necks are available to develop and test neck protectors as countermeasures, but each has its own limitations. The objective of this study was to develop a surrogate neck compatible with [...] Read more.
Road accidents could result in severe or fatal neck injuries. A few surrogate necks are available to develop and test neck protectors as countermeasures, but each has its own limitations. The objective of this study was to develop a surrogate neck compatible with the Hybrid III dummy, focused on tunable flexural stiffness and integrated angular sensors for kinematic feedback during impact tests. The neck features six 3D-printed surrogate vertebral bodies interconnected by rubber surrogate discs, providing a baseline flexibility to the surrogate fundamental spinal units. An adjustable inner cable and elastic elements hooked on the sides of vertebral elements allow to increase the flexural stiffness of the surrogate and to simulate the asymmetric behavior of the human neck. Neck flexural angles and axial compression are measured using a novel system made of wires, pulleys, and rotary potentiometers embedded in the neck base. A motion capture system and a load cell were used to determine the bending and torsional stiffness of the neck and to calibrate the sensors. Results showed that the neck flexural stiffness can be tuned between 3.29 and 5.76 Nm/rad. Torsional stiffness was 1.01 Nm/rad and compression stiffness can be tuned from 39 to 193 N/mm. Sensor flexural angles were compared with motion capture angles, showing an RMSE error of 1.35° during static testing and of 3° during dynamic testing. The developed neck could be a viable tool for investigating neck braces from a kinematic and kinetic perspective due to its inbuilt sensing ability and its tunable stiffness. Full article
(This article belongs to the Special Issue Applications of Body Worn Sensors and Wearables)
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46 pages, 6649 KB  
Review
Matrix WaveTM System for Mandibulo-Maxillary Fixation—Just Another Variation on the MMF Theme?—Part II: In Context to Self-Made Hybrid Erich Arch Bars and Commercial Hybrid MMF Systems—Literature Review and Analysis of Design Features
by Carl-Peter Cornelius, Paris Georgios Liokatis, Timothy Doerr, Damir Matic, Stefano Fusetti, Michael Rasse, Nils Claudius Gellrich, Max Heiland, Warren Schubert and Daniel Buchbinder
Craniomaxillofac. Trauma Reconstr. 2025, 18(3), 33; https://doi.org/10.3390/cmtr18030033 - 15 Jul 2025
Cited by 1 | Viewed by 4315
Abstract
Study design: Trends in the utilization of Mandibulo-Maxillary Fixation (MMF) are shifting nowadays from tooth-borne devices over specialized screws to hybrid MMF devices. Hybrid MMF devices come in self-made Erich arch bar modifications and commercial hybrid MMF systems (CHMMFSs). Objective: We survey the [...] Read more.
Study design: Trends in the utilization of Mandibulo-Maxillary Fixation (MMF) are shifting nowadays from tooth-borne devices over specialized screws to hybrid MMF devices. Hybrid MMF devices come in self-made Erich arch bar modifications and commercial hybrid MMF systems (CHMMFSs). Objective: We survey the available technical/clinical data. Hypothetically, the risk of tooth root damage by transalveolar screws is diminished by a targeting function of the screw holes/slots. Methods: We utilize a literature review and graphic displays to disclose parallels and dissimilarities in design and functionality with an in-depth look at the targeting properties. Results: Self-made hybrid arch bars have limitations to meet low-risk interradicular screw insertion sites. Technical/clinical information on CHMMFSs is unevenly distributed in favor of the SMARTLock System: positive outcome variables are increased speed of application/removal, the possibility to eliminate wiring and stick injuries and screw fixation with standoff of the embodiment along the attached gingiva. Inferred from the SMARTLock System, all four CHMMFs possess potential to effectively prevent tooth root injuries but are subject to their design features and targeting with the screw-receiving holes. The height profile and geometry shape of a CHMMFS may restrict three-dimensional spatial orientation and reach during placement. To bridge between interradicular spaces and tooth equators, where hooks or tie-up-cleats for intermaxillary cerclages should be ideally positioned under biomechanical aspects, can be problematic. The movability of their screw-receiving holes according to all six degrees of freedom differs. Conclusion: CHMMFSs allow simple immobilization of facial fractures involving dental occlusion. The performance in avoiding tooth root damage is a matter of design subtleties. Full article
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15 pages, 1557 KB  
Article
Association Between Microcalcification Patterns in Mammography and Breast Tumors in Comparison to Histopathological Examinations
by Iqbal Hussain Rizuana, Ming Hui Leong, Geok Chin Tan and Zaleha Md. Isa
Diagnostics 2025, 15(13), 1687; https://doi.org/10.3390/diagnostics15131687 - 2 Jul 2025
Cited by 4 | Viewed by 4632
Abstract
Background/Objectives: Accurately correlating mammographic findings with corresponding histopathologic features is considered one of the essential aspects of mammographic evaluation, guiding the next steps in cancer management and preventing overdiagnosis. The objective of this study was to evaluate patterns of mammographic microcalcifications and their [...] Read more.
Background/Objectives: Accurately correlating mammographic findings with corresponding histopathologic features is considered one of the essential aspects of mammographic evaluation, guiding the next steps in cancer management and preventing overdiagnosis. The objective of this study was to evaluate patterns of mammographic microcalcifications and their association with histopathological findings related to various breast tumors. Methods: 110 out of 3603 women had microcalcification of BIRADS 3 or higher and were subjected to stereotactic/ultrasound (USG) guided biopsies, and hook-wire localization excision procedures. Ultrasound and mammography images were reviewed by experienced radiologists using the standard American College of Radiology Breast-Imaging Reporting and Data System (ACR BI-RADS). Results: Our study showed that features with a high positive predictive value (PPV) of breast malignancy were heterogeneous (75%), fine linear/branching pleomorphic microcalcifications (66.7%), linear (100%), and segmental distributions (57.1%). Features that showed a higher risk of association with ductal carcinoma in situ (DCIS) were fine linear/branching pleomorphic (odds ratio (OR): 3.952), heterogeneous microcalcifications (OR: 3.818), segmental (OR: 5.533), linear (OR: 3.696), and regional (OR: 2.929) distributions. Furthermore, the features with higher risks associated with invasive carcinoma had heterogeneous (OR: 2.022), fine linear/branching pleomorphic (OR: 1.187) microcalcifications, linear (OR: 6.2), and regional (OR: 2.543) distributions. The features of associated masses in mammograms that showed a high PPV of malignancy had high density (75%), microlobulation (100%), and spiculated margins (75%). Conclusions: We concluded that specific patterns and distributions of microcalcifications were indeed associated with a higher risk of malignancy. Those with fine linear or branching pleomorphic and segmental distribution were at a higher risk of DCIS, whereas those with heterogeneous morphology with a linear distribution were at a higher risk of invasive carcinoma. Full article
(This article belongs to the Special Issue Recent Advances in Breast Cancer Imaging)
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15 pages, 499 KB  
Systematic Review
Aligners as a Therapeutic Approach in Impacted Canine Treatment: A Systematic Review
by Mateusz Wolny, Agata Sikora, Aneta Olszewska, Jacek Matys and Agata Czajka-Jakubowska
J. Clin. Med. 2025, 14(10), 3421; https://doi.org/10.3390/jcm14103421 - 14 May 2025
Cited by 3 | Viewed by 3212
Abstract
Background/Objectives: The growing demand for esthetic, less painful, and more comfortable orthodontic treatment has led to increasing use of aligner systems. Initially used for less complicated malocclusions, aligners are now being incorporated into complex treatment plans, including cases involving impacted teeth. While aligners [...] Read more.
Background/Objectives: The growing demand for esthetic, less painful, and more comfortable orthodontic treatment has led to increasing use of aligner systems. Initially used for less complicated malocclusions, aligners are now being incorporated into complex treatment plans, including cases involving impacted teeth. While aligners are a popular alternative to traditional fixed appliances, they still have limitations. This study aims to evaluate the effectiveness of aligner-based orthodontic treatment in patients with impacted or significantly ectopic canines. Methods: This study was conducted in accordance with the PRISMA guidelines. The search terms used were as follows: ‘Clear Aligner’ OR ‘Invisalign’ AND ‘Impacted Canine’ OR ‘Impacted Tooth’ OR ‘Ectopic Tooth’ OR ‘Ectopic Canine.’ A total of 1101 records were identified, of which 170 articles underwent screening. Fifteen articles were assessed for eligibility, and ultimately six case reports and one three-dimensional finite element analysis (FEA) study were included for both quantitative and qualitative synthesis. Results: According to the studies, additional appliances are often required to achieve favorable outcomes when treating impacted canines with aligner systems. Temporary anchorage devices (TADs) were used in 5 out of 9 reported cases for canine traction into the dental arch. In three cases, TADs were combined with sectional wires implemented as cantilevers. Elastics were used in 6 out of 9 cases for traction to the opposite arch, and in 5 out of 9 cases as interarch elastics attached to the aligners. Interarch elastics were applied in various ways, either directly to the aligners or to primary canines using hidden buttons inside pontics or dovetail hooks. Elastics were also anchored to the lower arch with class II, class III, or cross-arch (criss-cross) mechanics. Conclusions: This review highlights the promising potential of aligner systems in the treatment of impacted canines. However, additional auxiliaries, such as TADs, sectional wires, or elastics remain nearly essential for initial canine traction. Aligner systems offer versatile treatment options, and the possibility of reduced treatment time represents a valuable area for future research. Full article
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13 pages, 1709 KB  
Article
Unlocking the Potential of Computed Tomography-Guided Tracers in Pinpointing Lung Lesions during Surgery: A Collaborative Multi-Institutional Journey
by Rossella Potenza, Marco Andolfi, Andrea Dell’Amore, Marialuisa Lugaresi, Gabriella Roca, Leonardo Valentini, Chiara Catelli, Francesco Buia, Giampiero Dolci, Chiara Floridi, Riccardo Moretti, Claudia Colafigli, Majed Refai, Federico Rea, Francesco Puma and Niccolò Daddi
J. Clin. Med. 2024, 13(20), 6041; https://doi.org/10.3390/jcm13206041 - 10 Oct 2024
Cited by 2 | Viewed by 2598
Abstract
Background: Multiple techniques exist for the preoperative localization of small, deeply located solid or subsolid pulmonary nodules to guide limited thoracoscopic resection. This study aims to conduct a multi-institutional comparison of three different tomography-guided tracers’ methods. Methods: A retrospective multicenter cross-sectional study was [...] Read more.
Background: Multiple techniques exist for the preoperative localization of small, deeply located solid or subsolid pulmonary nodules to guide limited thoracoscopic resection. This study aims to conduct a multi-institutional comparison of three different tomography-guided tracers’ methods. Methods: A retrospective multicenter cross-sectional study was conducted. All patients suitable for CT-guided tracers with microcoil (GROUP1, n = 58), hook wire (GROUP2, n = 86), or bioabsorbable hydrogel plug (GROUP3, n = 33) were scheduled for video-assisted thoracoscopic wedge resection. Outcome variables: successful nodule localization, safety, and the feasibility of the tracers’ placement. A χ2 test or Fisher’s test for expected numbers less than five and a Kruskal–Wallis test were used to analyze the categorical and continuous variables, respectively. For the power calculations, we used G*Power version 3.1.9.6. Results: One hundred seventy-seven patients underwent the localization and resection of 177 nodules detected with three different CT-guided tracers. A significant difference was recorded for cancer history (p = 0.030), respiratory function, Charlson comorbidity index (p = 0.018), lesion type (p < 0.0001), distance from pleura surface (p < 0.0001), and time between preoperative CT-guided tracers and surgical procedures (p < 0.0001). Four post-procedural complications were recorded and in GROUP2, four cases of tracer dislocations occurred. Finally, hook wire group was associated with the shortest surgical time (93 min, p = 0.001). Conclusions: All methods were feasible and efficient, resulting in a 100% success rate for the microcoils and the bioabsorbable hydrogel plugs and a 94.2% success rate for the hook wires. Our results highlight the need to choose a technique that is less stressful for the patient and helps the surgeon by extending the approach to deep nodules and resecting over the course of several days from deployment. Full article
(This article belongs to the Special Issue Thoracic Surgery: Recent Developments and Future Challenges)
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14 pages, 2231 KB  
Review
Current Status and Future Perspectives of Preoperative and Intraoperative Marking in Thoracic Surgery
by Toyofumi Fengshi Chen-Yoshikawa, Shota Nakamura, Harushi Ueno, Yuka Kadomatsu, Taketo Kato and Tetsuya Mizuno
Cancers 2024, 16(19), 3284; https://doi.org/10.3390/cancers16193284 - 26 Sep 2024
Cited by 10 | Viewed by 2568
Abstract
The widespread implementation of lung cancer screening and thin-slice computed tomography (CT) has led to the more frequent detection of small nodules, which are commonly referred to thoracic surgeons. Surgical resection is the final diagnostic and treatment option for such nodules; however, surgeons [...] Read more.
The widespread implementation of lung cancer screening and thin-slice computed tomography (CT) has led to the more frequent detection of small nodules, which are commonly referred to thoracic surgeons. Surgical resection is the final diagnostic and treatment option for such nodules; however, surgeons must perform preoperative or intraoperative markings for the identification of such nodules and their precise resection. Historically, hook-wire marking has been performed more frequently worldwide; however, lethal complications, such as air embolism, have been reported. Therefore, several surgeons have recently attempted to develop novel preoperative and intraoperative markers. For example, transbronchial markings, such as virtual-assisted lung mapping and intraoperative markings using cone-beam computed tomography, have been developed. This review explores various marking methods that have been practically applied for a better understanding of preoperative and intraoperative markings in thoracic surgery. Recently, several attempts have been made to perform intraoperative molecular imaging and dynamic virtual three-dimensional computed tomography for the localization, diagnosis, and margin assessment of small nodules. In this narrative review, the current status and future perspectives of preoperative and intraoperative markings in thoracic surgery are examined for a better understanding of these techniques. Full article
(This article belongs to the Special Issue Advances in Oncological Imaging)
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15 pages, 19767 KB  
Article
Fabrication of Helical Carbon Fiber Skeleton Using Arc Glow Discharge Method
by Xiye Chen, Haiyong Chen, Yongjun Bao, Yuhan Meng and Zhigang Jiang
Materials 2024, 17(17), 4181; https://doi.org/10.3390/ma17174181 - 23 Aug 2024
Cited by 1 | Viewed by 1532
Abstract
An arc glow discharge device was used to prepare a helical carbon fiber skeleton with helical carbon fibers hooked to each other by spraying a hydrogen and ethanol mixture onto the iron wire substrate through the discharge area, using anhydrous ethanol as the [...] Read more.
An arc glow discharge device was used to prepare a helical carbon fiber skeleton with helical carbon fibers hooked to each other by spraying a hydrogen and ethanol mixture onto the iron wire substrate through the discharge area, using anhydrous ethanol as the carbon source. The samples were characterized by SEM, EDS, Raman and XPS. A growth mechanism of helical carbon fiber driven by C sp3 was proposed. The various growth modes of carbon fiber during the formation of carbon fiber skeleton were investigated. A ring appearance that indicated a change in the direction of carbon fiber growth was observed. And double helical carbon fiber was constructed from single helical carbon fiber in two ways. Super-large carbon fiber with a diameter of about 13 μm was observed, and it was speculated that this super-large carbon fiber is the backbone of the carbon fiber skeleton. The mechanical properties of the carbon fiber skeleton are isotropic. Full article
(This article belongs to the Section Carbon Materials)
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16 pages, 6015 KB  
Review
Pars Interarticularis Fractures Treated with Minimally Invasive Surgery: A Literature Review
by Adrienne Minor, Benjamin R. Klein, Mareshah N. Sowah, Kayla Etienne and Allan D. Levi
J. Clin. Med. 2024, 13(2), 581; https://doi.org/10.3390/jcm13020581 - 19 Jan 2024
Cited by 8 | Viewed by 12599
Abstract
Recurrent stress on the isthmic pars interarticularis often leads to profound injury and symptom burden. When conservative and medical management fail, there are various operative interventions that can be used. The current review details the common clinical presentation and treatment of pars injury, [...] Read more.
Recurrent stress on the isthmic pars interarticularis often leads to profound injury and symptom burden. When conservative and medical management fail, there are various operative interventions that can be used. The current review details the common clinical presentation and treatment of pars injury, with a special focus on the emerging minimally invasive procedures used in isthmic pars interarticularis repair. PubMed and Google Scholar database literature reviews were conducted. The keywords and phrases that were searched include but were not limited to; “history of spondylolysis”, “pars interarticularis”, “pars defect”, “conventional surgical repair of pars”, and “minimally invasive repair of pars”. The natural history, conventional presentation, etiology, risk factors, and management of pars interarticularis injury are discussed by the authors. The surgical interventions described include the Buck’s repair, Morscher Screw-Hook repair, Scott’s Wiring technique, and additional pedicle screw-based repairs. Minimally invasive techniques are also reviewed, including the Levi technique. Surgical intervention has been proven to be safe and effective in managing pars interarticularis fractures. However, minimally invasive techniques often provide additional benefit to patients such as reducing damage of surrounding structures, decreasing postoperative pain, and limiting the time away from sports and other activities. Full article
(This article belongs to the Special Issue Advances in Minimally Invasive Spine Surgery)
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10 pages, 4237 KB  
Article
Implementation of Individualized Low-Dose Computed Tomography-Guided Hook Wire Localization of Pulmonary Nodules: Feasibility and Safety in the Clinical Setting
by Wei Wei, Shi-Geng Wang, Jing-Yi Zhang, Xiao-Yu Togn, Bei-Bei Li, Xin Fang, Ren-Wang Pu, Yu-Jing Zhou and Yi-Jun Liu
Diagnostics 2023, 13(20), 3235; https://doi.org/10.3390/diagnostics13203235 - 17 Oct 2023
Cited by 7 | Viewed by 1977
Abstract
Background: CT-guided hook-wire localization is an essential step in the management of small pulmonary nodules. Few studies, however, have focused on reducing radiation exposure during the procedure. Purpose: This study aims to explore the feasibility of implementing a low-dose computed tomography (CT)-guided hook [...] Read more.
Background: CT-guided hook-wire localization is an essential step in the management of small pulmonary nodules. Few studies, however, have focused on reducing radiation exposure during the procedure. Purpose: This study aims to explore the feasibility of implementing a low-dose computed tomography (CT)-guided hook wire localization using tailored kVp based on patients’ body size. Materials and Methods: A total of 151 patients with small pulmonary nodules were prospectively enrolled for CT-guided hook wire localization using individualized low-dose CT (LDCT) vs. standard-dose CT (SDCT) protocols. Radiation dose, image quality, characteristics of target nodules and procedure-related variables were compared. All variables were analyzed using Chi-Square and Student’s t-test. Results: The mean CTDIvol was significantly reduced for LDCT (for BMI ≤ 21 kg/m2, 0.56 ± 0.00 mGy and for BMI > 21 kg/m2, 1.48 ± 0.00 mGy) when compared with SDCT (for BMI ≤ 21 kg/m2, 5.24 ± 0.95 mGy and for BMI > 21 kg/m2, 6.69 ± 1.47 mGy). Accordingly, the DLP of LDCT was significantly reduced as compared with that of SDCT (for BMI ≤ 21 kg/m2, 56.86 ± 4.73 vs. 533.58 ± 122.06 mGy.cm, and for BMI > 21 kg/m2, 167.02 ± 38.76 vs. 746.01 ± 230.91 mGy.cm). In comparison with SDCT, the effective dose (ED) of LDCT decreased by an average of 89.42% (for BMI ≤ 21 kg/m2) and 77.68% (for BMI > 21 kg/m2), respectively. Although the images acquired with the LDCT protocol yielded inferior quality to those acquired with the SDCT protocol, they were clinically acceptable for hook wire localization. Conclusions: LDCT-guided localization can provide safety and nodule detection performance comparable to SDCT-guided localization, benefiting radiation dose reduction dramatically, especially for patients with small body mass indexes. Full article
(This article belongs to the Special Issue Technologies in the Diagnosis of Lung Diseases)
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13 pages, 870 KB  
Article
Percutaneous Computed Tomography (CT)-Guided Localization with Indocyanine Green for the Thoracoscopic Resection of Small Pulmonary Nodules
by Emanuele Voulaz, Veronica Maria Giudici, Ezio Lanza, Edoardo Bottoni, Umberto Cariboni, Alessandro Crepaldi, Giuseppe Ferrillo, Giuseppe Marulli, Marco Alloisio, Giuseppe Mangiameli and Alberto Testori
J. Clin. Med. 2023, 12(19), 6149; https://doi.org/10.3390/jcm12196149 - 23 Sep 2023
Cited by 17 | Viewed by 2545
Abstract
Background: The identification of small lung nodules is challenging during mini-invasive thoracic surgery. Unable to palpate them directly, surgeons have developed several methods to preoperatively localize pulmonary nodules, including the computed tomography-guided positioning of coils or metallic landmarks (hook wire) or bronchoscopic marking. [...] Read more.
Background: The identification of small lung nodules is challenging during mini-invasive thoracic surgery. Unable to palpate them directly, surgeons have developed several methods to preoperatively localize pulmonary nodules, including the computed tomography-guided positioning of coils or metallic landmarks (hook wire) or bronchoscopic marking. Methods: We present a series of patients scheduled for the video-assisted thoracoscopic sublobar resection of small pulmonary nodules, in which we performed preoperative percutaneous computed tomography (CT)-guided nodule localization through the injection of a mixture of indocyanine green and human albumin. Results: A total of 40 patients underwent a preoperative CT-guided injection of indocyanine green followed by VATS resection within 24 h. Patients tolerated the procedure well, no pain medication was administrated, and no complications were observed during the marking procedure. All pulmonary nodules were easily detected and successfully resected. Conclusion: the near-infrared dye marking solution of indocyanine green (ICG) with diluted human albumin was safe, effective, and easy to perform. The ICG solution has the potential to facilitate the accurate localization and resection of pulmonary nodules during VATS surgery, avoiding the risk of marker displacement/migration. Full article
(This article belongs to the Section Respiratory Medicine)
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