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41 Results Found

  • Article
  • Open Access
18 Citations
4,895 Views
15 Pages

Brain Computer Interface-Based Action Observation Game Enhances Mu Suppression in Patients with Stroke

  • Hyoseon Choi,
  • Hyunmi Lim,
  • Joon Woo Kim,
  • Youn Joo Kang and
  • Jeonghun Ku

2 December 2019

Action observation (AO), based on the mirror neuron theory, is a promising strategy to promote motor cortical activation in neurorehabilitation. Brain computer interface (BCI) can detect a user’s intention and provide them with brain state-depe...

  • Review
  • Open Access
11 Citations
3,879 Views
10 Pages

2 August 2024

Background: Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor symptoms such as tremors, rigidity, and bradykinesia. Rehabilitation utilizing mirror neurons leverages the brain’s capacity for action observatio...

  • Article
  • Open Access
4 Citations
2,759 Views
15 Pages

4 August 2021

Action observation (AO)-based brain-computer interface (BCI) is an important technology in stroke rehabilitation training. It has the advantage of simultaneously inducing steady-state motion visual evoked potential (SSMVEP) and activating sensorimoto...

  • Article
  • Open Access
13 Citations
3,096 Views
23 Pages

1 September 2023

Virtual Co-embodiment (vc) is a relatively new field of VR, enabling a user to share control of an avatar with other users or entities. According to a recent study, vc was shown to have the highest motor skill learning efficiency out of three VR-base...

  • Communication
  • Open Access
4 Citations
3,197 Views
16 Pages

Multimodal Drumming Education Tool in Mixed Reality

  • James Pinkl,
  • Julián Villegas and
  • Michael Cohen

First-person VR- and MR-based Action Observation research has thus far yielded both positive and negative findings in studies observing such tools’ potential to teach motor skills. Teaching drumming, particularly polyrhythms, is a challenging m...

  • Article
  • Open Access
2,022 Views
16 Pages

The Effects of Action Observation Speed on Motor Function in Patients with Chronic Low Back Pain: From Observation to Execution

  • Mónica Grande-Alonso,
  • Manuel Estradera-Bel,
  • Carlos Forner-Álvarez,
  • Ferran Cuenca-Martínez,
  • Celia Vidal-Quevedo,
  • Alba Paris-Alemany and
  • Roy La Touche

30 December 2024

Objective: The objective of this study was to examine the effect of observing actions at different speeds on the speed of motor task performance in subsequent actions. Methods: Sixty individuals, divided equally between those with non-specific chroni...

  • Article
  • Open Access
10 Citations
5,192 Views
15 Pages

21 November 2019

Action observation (AO) and motor imagery (MI) are useful techniques in neurorehabilitation. Previous studies have reported that AO and MI facilitate corticospinal excitability only in those muscles that are active when actually performing the observ...

  • Article
  • Open Access
28 Citations
6,994 Views
18 Pages

12 July 2019

The aim of the present study was to explore the pain modulation effects of motor imagery (MI) and action observation (AO) of specific neck therapeutic exercises both locally, in the cervical region, and remotely. A single-blind, placebo clinical tria...

  • Review
  • Open Access
1 Citations
1,939 Views
7 Pages

Effects of Movement Representation Strategies on Cardiovascular Disease: A Literature Review

  • Ferran Cuenca-Martínez,
  • Elena Muñoz-Gómez,
  • Sara Mollà-Casanova and
  • Núria Sempere-Rubio

1 July 2023

Motor imagery (MI) and action observation (AO) techniques are two movement representation strategies that are widely used in multiple fields of study. MI is defined as the cognitive skill that involves the representation of an action, internally, wit...

  • Review
  • Open Access
19 Citations
4,318 Views
14 Pages

21 July 2022

Parkinson’s disease (PD) is a neurodegenerative disease that alters gait patterns from early stages. The visuo-motor training strategies such as action observation (AO) and motor imagery (MI) that are based on the activity of the mirror neuron...

  • Review
  • Open Access
30 Citations
10,155 Views
21 Pages

The Role of Movement Representation Techniques in the Motor Learning Process: A Neurophysiological Hypothesis and a Narrative Review

  • Ferran Cuenca-Martínez,
  • Luis Suso-Martí,
  • Jose Vicente León-Hernández and
  • Roy La Touche

We present a neurophysiological hypothesis for the role of motor imagery (MI) and action observation (AO) training in the motor learning process. The effects of movement representation in the brain and those of the cortical–subcortical networks...

  • Systematic Review
  • Open Access
14 Citations
5,114 Views
18 Pages

The Effects of Action Observation Therapy as a Rehabilitation Tool in Parkinson’s Disease Patients: A Systematic Review

  • Ioannis Giannakopoulos,
  • Panagiota Karanika,
  • Charalambos Papaxanthis and
  • Panagiotis Tsaklis

During Action Observation (AO), patients observe human movements that they then try to imitate physically. Until now, few studies have investigated the effectiveness of it in Parkinson’s disease (PD). However, due to the diversity of interventi...

  • Protocol
  • Open Access
2,510 Views
10 Pages

Upper Limb Electromyographic Responses to Motor Imagery and Action Observation in Acquired Brain Injury

  • Sara Santiago-Martín,
  • Ana Belén Calvo-Vera,
  • Beatriz María Bermejo-Gil and
  • Ana María Martín-Nogueras

11 March 2024

Acquired Brain Injuries are one of the leading causes of mortality and disability worldwide. One of the most frequent sequelae is motor impairment of the upper limbs, which affects people’s functionality and quality of life. Following the disco...

  • Article
  • Open Access
16 Citations
5,561 Views
10 Pages

This study aimed to investigate the effect of motor imagery (MI) intervention with action observation (AO) on upper extremity function and corticospinal activation in stroke patients. MI and AO are two forms of motion simulation that activate the mot...

  • Article
  • Open Access
6 Citations
2,703 Views
16 Pages

21 October 2022

Action observation (AO) combined with motor imagery (MI) was verified as more effective in improving limb function than AO or MI alone, while the underlying mechanism of swallowing was ambiguous. The study aimed at exploring the efficacy of AO combin...

  • Feature Paper
  • Short Note
  • Open Access
9 Citations
5,641 Views
8 Pages

Action Observation in People with Parkinson’s Disease. A Motor–Cognitive Combined Approach for Motor Rehabilitation. A Preliminary Report

  • Walter Di Iorio,
  • Alessandro Ciarimboli,
  • Giorgio Ferriero,
  • Michele Feleppa,
  • Luigi Baratto,
  • Giuseppe Matarazzo,
  • Giovanni Gentile,
  • Stefano Masiero and
  • Patrizio Sale

The aim of this study was to assess the role of Action Observation (AO) to improve balance, gait, reduce falls, and to investigate the changes in P300 pattern. Five cognitively intact People with Parkinson’s disease (PwP) were enrolled in this...

  • Article
  • Open Access
955 Views
24 Pages

11 August 2025

Age of Information (AoI) is a newly introduced metric that quantifies the freshness and timeliness of data, playing a crucial role in applications reliant on time-sensitive information. Minimizing AoI through optimal scheduling is challenging, especi...

  • Article
  • Open Access
24 Citations
5,454 Views
20 Pages

The motor imagery (MI)-based brain computer interface (BCI) is an intuitive interface that enables users to communicate with external environments through their minds. However, current MI-BCI systems ask naïve subjects to perform unfamiliar MI t...

  • Article
  • Open Access
7 Citations
3,232 Views
9 Pages

Motor Cortical Activity during Observing a Video of Real Hand Movements versus Computer Graphic Hand Movements: An MEG Study

  • Yu-Wei Hsieh,
  • Meng-Ta Lee,
  • Yu-Hsuan Lin,
  • Li-Ling Chuang,
  • Chih-Chi Chen and
  • Chia-Hsiung Cheng

23 December 2020

Both action observation (AO) and virtual reality (VR) provide visual stimuli to trigger brain activations during the observation of actions. However, the mechanism of observing video movements performed by a person’s real hand versus that perfo...

  • Article
  • Open Access
3,876 Views
13 Pages

Distinct Effects of Brain Activation Using tDCS and Observational Practice: Implications for Motor Rehabilitation

  • Julianne McLeod,
  • Anuj Chavan,
  • Harvey Lee,
  • Sahar Sattari,
  • Simrut Kurry,
  • Miku Wake,
  • Zia Janmohamed,
  • Nicola Jane Hodges and
  • Naznin Virji-Babul

13 February 2024

Complex motor skills can be acquired while observing a model without physical practice. Transcranial direct-current stimulation (tDCS) applied to the primary motor cortex (M1) also facilitates motor learning. However, the effectiveness of observation...

  • Brief Report
  • Open Access
1,015 Views
7 Pages

3 October 2025

This study aims to investigate whether a combined action observation–motor imagery practice may enhance the effects of conventional physical rehabilitation in a stroke survivor population. A total of 8 (7 male, 1 female) post-stroke patients wi...

  • Article
  • Open Access
2 Citations
2,253 Views
11 Pages

Action potential duration (APD) alternans, an alternating phenomenon between action potentials in cardiomyocytes, causes heart arrhythmia when the heart rate is high. However, some of the APD alternans observed in clinical trials occurs under slow he...

  • Article
  • Open Access
15 Citations
3,142 Views
17 Pages

Corticomotor Plasticity Underlying Priming Effects of Motor Imagery on Force Performance

  • Typhanie Dos Anjos,
  • Aymeric Guillot,
  • Yann Kerautret,
  • Sébastien Daligault and
  • Franck Di Rienzo

13 November 2022

The neurophysiological processes underlying the priming effects of motor imagery (MI) on force performance remain poorly understood. Here, we tested whether the priming effects of embedded MI practice involved short-term changes in corticomotor conne...

  • Systematic Review
  • Open Access
366 Views
16 Pages

Neurorehabilitation-Based Movement Representation Techniques in the Management of Craniocervical and Orofacial Pain: A Systematic Review of Randomized Controlled Trials

  • Alberto García-Alonso,
  • Luis Polo-Ferrero,
  • Ana Silvia Puente-González,
  • Tamara Manso-Hierro,
  • Marta Beatriz Carrera-Villegas and
  • Roberto Méndez-Sánchez

15 January 2026

Background: Craniocervical pain and temporomandibular disorders (TMDs) are prevalent, interconnected conditions. While Movement Representation Techniques (MRTs) are cognitive interventions targeting central pain mechanisms, their specific efficacy he...

  • Article
  • Open Access
9 Citations
4,075 Views
18 Pages

Novel Facet of an Old Dietary Molecule? Direct Influence of Caffeine on Glucose and Biogenic Amine Handling by Human Adipocytes

  • Wiem Haj Ahmed,
  • Nathalie Boulet,
  • Anaïs Briot,
  • Barry J. Ryan,
  • Gemma K. Kinsella,
  • Jeffrey O’Sullivan,
  • Francisco Les,
  • Josep Mercader-Barceló,
  • Gary T. M. Henehan and
  • Christian Carpéné

23 June 2021

Caffeine is a plant alkaloid present in food and beverages consumed worldwide. It has high lipid solubility with recognized actions in the central nervous system and in peripheral tissues, notably the adipose depots. However, the literature is scant...

  • Article
  • Open Access
12 Citations
7,237 Views
17 Pages

1 March 2021

The seasonal precipitation (SP) trend and its sensitivity to teleconnection patterns over the East Mediterranean (EM) region remain inconsistent. Based on rainfall records during 1974–2016 at seven meteorological stations in the Gaza region, this stu...

  • Study Protocol
  • Open Access
6 Citations
4,841 Views
14 Pages

New Approaches Based on Non-Invasive Brain Stimulation and Mental Representation Techniques Targeting Pain in Parkinson’s Disease Patients: Two Study Protocols for Two Randomized Controlled Trials

  • Yeray González-Zamorano,
  • Josué Fernández-Carnero,
  • Francisco José Sánchez-Cuesta,
  • Aida Arroyo-Ferrer,
  • Athanasios Vourvopoulos,
  • Patricia Figueiredo,
  • José Ignacio Serrano and
  • Juan Pablo Romero

Pain is an under-reported but prevalent symptom in Parkinson’s Disease (PD), impacting patients’ quality of life. Both pain and PD conditions cause cortical excitability reduction and non-invasive brain stimulation. Mental representation...

  • Article
  • Open Access
1 Citations
2,061 Views
13 Pages

Native Pig Neutrophil Products: Insights into Their Antimicrobial Activity

  • Eric Fernández-De La Cruz,
  • Joanna Wessely-Szponder,
  • Miguel Viñas,
  • Teresa Vinuesa,
  • Alexandra Merlos,
  • Marta Jorba,
  • Paula Espinal and
  • Ester Fusté

Cationic antimicrobial peptides are molecules with potential applications for treating infections due to their antimicrobial and immunomodulatory properties. The aim of this work was to explore the antimicrobial activity and mechanisms of action of a...

  • Article
  • Open Access
3 Citations
2,209 Views
12 Pages

A Method for Using Video Presentation to Increase Cortical Region Activity during Motor Imagery Tasks in Stroke Patients

  • Kengo Fujiwara,
  • Rikako Shimoda,
  • Masatomo Shibata,
  • Yoshinaga Awano,
  • Koji Shibayama and
  • Toshio Higashi

23 December 2022

Previous studies have reported that stroke patients have difficulty recalling the motor imagery (MI) of a task, also known as MI vividness. Research on combining MI with action observation is gaining importance as a method to improve MI vividness. We...

  • Article
  • Open Access
1 Citations
4,340 Views
14 Pages

The Impact of Different Telerehabilitation Methods on Peripheral Muscle Strength and Aerobic Capacity in COPD Patients: A Randomized Controlled Trial

  • Amine Ataç,
  • Esra Pehlivan,
  • Fulya Senem Karaahmetoğlu,
  • Zeynep Betül Özcan,
  • Halit Çınarka,
  • Mustafa Çörtük,
  • Kürsad Nuri Baydili and
  • Erdoğan Çetinkaya

20 September 2024

Lung diseases have profound effects on the aging population. We aimed to hypothesize and investigate the effect of remote pulmonary telerehabilitation and motor imagery (MI) and action observation (AO) methods on the clinical status of elderly chroni...

  • Article
  • Open Access
41 Citations
8,196 Views
23 Pages

Neuroprotective Mechanisms of Three Natural Antioxidants on a Rat Model of Parkinson’s Disease: A Comparative Study

  • Lyubka P. Tancheva,
  • Maria I. Lazarova,
  • Albena V. Alexandrova,
  • Stela T. Dragomanova,
  • Ferdinando Nicoletti,
  • Elina R. Tzvetanova,
  • Yordan K. Hodzhev,
  • Reni E. Kalfin,
  • Simona A. Miteva and
  • Atanas G. Atanasov
  • + 2 authors

We compared the neuroprotective action of three natural bio-antioxidants (AOs): ellagic acid (EA), α-lipoic acid (LA), and myrtenal (Myrt) in an experimental model of Parkinson’s disease (PD) that was induced in male Wistar rats through a...

  • Article
  • Open Access
1 Citations
2,528 Views
18 Pages

The Effect of Baseline on Toddler Event-Related Mu-Rhythm Modulation

  • Caterina Piazza,
  • Eleonora Visintin,
  • Gianluigi Reni and
  • Rosario Montirosso

31 August 2021

Event-related mu-rhythm activity has become a common tool for the investigation of different socio-cognitive processes in pediatric populations. The estimation of the mu-rhythm desynchronization/synchronization (mu-ERD/ERS) in a specific task is usua...

  • Article
  • Open Access
18 Citations
6,035 Views
20 Pages

Systematic Balance Exercises Influence Cortical Activation and Serum BDNF Levels in Older Adults

  • Jadwiga Kubica,
  • Jadwiga Szymura,
  • Aleksandra Domagalik,
  • Slawomir Golda,
  • Magdalena Wiecek,
  • Magdalena Fafrowicz,
  • Tadeusz Marek and
  • Joanna Pera

7 November 2019

We sought to investigate whether systematic balance training modulates brain area activity responsible for postural control and influence brain-derived neurotrophic factor (BDNF) mRNA protein expression. Seventy-four older adults were randomly divide...

  • Article
  • Open Access
1,309 Views
18 Pages

Mangrove forests are intertidal ecosystems that harbor diverse microbial communities essential for biogeochemical cycles and energy flow. This study investigated the seasonal and spatial patterns of bacterial communities in the artificially introduce...

  • Feature Paper
  • Article
  • Open Access
8 Citations
2,425 Views
17 Pages

Structural Prediction and Characterization of Canavalia grandiflora (ConGF) Lectin Complexed with MMP1: Unveiling the Antiglioma Potential of Legume Lectins

  • Rodrigo Bainy Leal,
  • Josiane Mann,
  • Vanir Reis Pinto-Junior,
  • Messias Vital Oliveira,
  • Vinicius Jose Silva Osterne,
  • Ingrid Alessandra Victoria Wolin,
  • Ana Paula Machado Nascimento,
  • Priscilla Gomes Welter,
  • Valeria Maria Sousa Ferreira and
  • Benildo Sousa Cavada
  • + 3 authors

20 October 2022

A glioblastoma (GBM) is a highly malignant primary brain tumor with a poor prognosis because of its invasiveness and high resistance to current therapies. In GBMs, abnormal glycosylation patterns are associated with malignancy, which allows for the u...

  • Article
  • Open Access
6 Citations
6,147 Views
21 Pages

This article challenges the narrow definition of informal settlements as solely lacking a formal framework, which overlooks the dynamic city-making and urban design processes within these areas. Communities’ self-building processes and areas&rs...

  • Article
  • Open Access
2,021 Views
25 Pages

The Proapoptotic Effect of MB-653 Is Associated with the Modulation of Metastasis and Invasiveness-Related Signalling Pathways in Human Colorectal Cancer Cells

  • Libor Sokoli,
  • Peter Takáč,
  • Mariana Budovská,
  • Radka Michalková,
  • Martin Kello,
  • Natália Nosálová,
  • Ľudmila Balážová,
  • Šimon Salanci and
  • Ján Mojžiš

6 January 2025

Colorectal cancer is one of the most common cancers worldwide and has a high mortality rate. In this study, we investigated the cytotoxic, proapoptotic, and anti-invasive effects of the synthetic indole phytoalexin MB-653. The antiproliferative effec...

  • Article
  • Open Access
2 Citations
2,535 Views
16 Pages

L-Aminoguanidine Induces Imbalance of ROS/RNS Homeostasis and Polyamine Catabolism of Tomato Roots after Short-Term Salt Exposure

  • Ágnes Szepesi,
  • László Bakacsy,
  • Attila Fehér,
  • Henrietta Kovács,
  • Péter Pálfi,
  • Péter Poór,
  • Réka Szőllősi,
  • Orsolya Kinga Gondor,
  • Tibor Janda and
  • Laura Zsigmond
  • + 3 authors

15 August 2023

Polyamine (PA) catabolism mediated by amine oxidases is an important process involved in fine-tuning PA homeostasis and related mechanisms during salt stress. The significance of these amine oxidases in short-term responses to salt stress is, however...

  • Systematic Review
  • Open Access
1 Citations
8,123 Views
48 Pages

The Impact of Visualization on Stroke Rehabilitation in Adults: A Systematic Review of Randomized Controlled Trials on Guided and Motor Imagery

  • Andrea Calderone,
  • Alfredo Manuli,
  • Francesca Antonia Arcadi,
  • Annalisa Militi,
  • Simona Cammaroto,
  • Maria Grazia Maggio,
  • Serena Pizzocaro,
  • Angelo Quartarone,
  • Alessandro Marco De Nunzio and
  • Rocco Salvatore Calabrò

Background/Objectives: Guided imagery techniques, which include mentally picturing motions or activities to help motor recovery, are an important part of neuroplasticity-based motor therapy in stroke patients. Motor imagery (MI) is a kind of guided i...

  • Article
  • Open Access
4 Citations
3,702 Views
24 Pages

Local Site Effects Investigation in Durres City (Albania) Using Ambient Noise, after the 26 November 2019 (M6.4) Destructive Earthquake

  • Nikos Theodoulidis,
  • Edmond Dushi,
  • Llambro Duni,
  • Ioannis Grendas,
  • Areti Panou,
  • Ardit Hajrullai,
  • Neki Kuka and
  • Rexhep Koci

8 November 2022

Site characterization of metropolitan areas, especially after an earthquake, is of paramount importance for interpretation of spatial damage distribution and taking measures that assure realistic design actions to strengthen existing constructions an...

  • Review
  • Open Access
5 Citations
5,332 Views
22 Pages

Review of Applications of Remote Sensing towards Sustainable Agriculture in the Northern Savannah Regions of Ghana

  • Abdul-Wadood Moomen,
  • Lily Lisa Yevugah,
  • Louvis Boakye,
  • Jeff Dacosta Osei and
  • Francis Muthoni

This paper assesses evidence-based applications of Remote Sensing for Sustainable and Precision Agriculture in the Northern Savanna Regions of Ghana for three decades (1990–2023). During this period, there have been several government policy in...