35 Results Found

Analysis of neural encoding and plasticity processes frequently relies on studying spatial patterns of activity-induced immediate early genes’ expression, such as c-fos. Quantitatively analyzing the numbers of cells expressing the Fos protein o...

Recently, phenotyping has become one of the main bottlenecks in plant breeding and fundamental plant science. This is particularly true for plant disease assessment, which has to deal with time-consuming evaluations and the subjectivity of visual ass...

Most of the time, the deep analysis of a biological sample requires the acquisition of images at different time points, using different modalities and/or different stainings. This information gives morphological, functional, and physiological insight...

Development of resistant cultivars for Fusarium basal rot (FBR), a fungal disease caused by the soil-borne fungus Fusarium oxysporum f.sp. cepae (FOC), is a major breeding goal for onion breeding programs around the world. Currently, the selection of...

Segmentation is one of the most important steps in microscopy image analysis. Unfortunately, most of the methods use fluorescence images for this task, which is not suitable for analysis that requires a knowledge of area occupied by cells and an expe...

This article targets cell biologists who use fluorescence microscopy but lack automatic tools to summarize and manage their image datasets. When using microscopy to document a phenotype, multiple and random pictures are required to reflect the biolog...

Sediment accumulation in irrigation channels poses a significant challenge to water resource management, impacting hydraulic efficiency and agricultural sustainability. This study introduces an innovative multidisciplinary framework that integrates a...

Background: Leiomyomas are benign tumors that may cause symptoms and affect fertility, requiring careful assessment. Magnetic Resonance Imaging (MRI) becomes crucial when ultrasonography results are inconclusive; however, it is expensive and time-con...

Traditionally histology is the gold standard for the validation of imaging experiments. Matching imaging slices and histological sections and the precise outlining of corresponding tissue structures are difficult. Challenges are based on differences...

This paper explains a proposed algorithm for severity estimation of plant leaf diseases by using maize leaf diseased samples. In the literature, a number of researchers have addressed the problem of plant leaf disease severity estimation, but a few,...

(1) Background: Prostate-specific membrane antigen (PSMA)-derived tumour volume (PSMA-TV) and total lesion PSMA (TL-PSMA) from PSMA PET/CT scans are promising biomarkers for assessing treatment response in prostate cancer (PCa). Currently, it is uncl...

Using a high-throughput neuroanatomical screen of histological brain sections developed in collaboration with the International Mouse Phenotyping Consortium, we previously reported a list of 198 genes whose inactivation leads to neuroanatomical pheno...

Currently, for Pinus pinea L., a valuable Mediterranean forest species in Catalonia, Spain, pinecone production is quantified visually before harvest with a manual count of the number of pinecones of the third year in a selection of trees and then ex...

Natural or artificial light allows us to see and analyze matter with our eyes, which are the first tools used in several experiments. In geosciences, particularly in mineralogy, light is used for optical microscopy observations. Reflected and transmi...

In this study, we quantitatively investigate the impact of 1.4 wt.% chromium and 1.4 wt.% molybdenum additions on pearlitic microstructure characteristics in 1 wt.% carbon steels. The study was carried out using a combination of experimental methods...

Following tooth extraction, the bone structure is prone to atrophic changes. Alveolar ridge resorption can compromise subsequent implant treatment not only at the extraction site itself but also by affecting the bone support of adjacent teeth. Variou...

Galectins are a family of beta-galactoside-binding proteins that are characterised by their carbohydrate recognition domain (CRD) and include galectin-1 and galectin-3. These galectins have been implicated in numerous diseases due to their pleiotropi...

Background/Objectives: Amelogenesis imperfecta (AI) represents a heterogeneous group of inherited disorders affecting the quality and quantity of dental enamel, making clinical diagnosis challenging. This study aimed to identify genetic variants in S...

Biocytin, a chemical compound that is an amide formed from the vitamin biotin and the amino acid L-lysine, has been used as a histological dye to stain nerve cells. Electrophysiological activity and morphology are two key characteristics of neurons,...

Background/Objectives: Evaluation of artifact expression in CBCT images caused by different intracanal medications (IMs) considering variations in scanning and reconstruction protocols. Reconstruction protocols refer to the specific parameters and im...

Pathological cleavage of type II collagen (Col2) and generation of Col2 neoepitopes can serve as useful molecular markers of the progression of osteoarthritis (OA). One of such potential biomarkers is type II collagen neoepitope C2C. The aim of this...

The purpose of this study was to investigate changes in bone trabecular structure during adolescence using the fractal analysis (FA) method on hand–wrist radiographs (HWRs) and to evaluate the relationship of these changes with pubertal growth...

The systematic use of plant protection products is now being called into question with the growing awareness of the risks they can represent for the environment and human health. The application of precision agriculture technologies helps to improve...

The determination of uncertainty in porosity analysis based on X-ray computed tomography (XCT) images is currently the focus of research. This study aims to contribute to that by investigating the variation in porosity analysis resulting only from th...

Intracellular calcium (Ca2+) is the central regulator of heart contractility. Indeed, it couples the electrical signal, which pervades the myocardium, with cardiomyocytes contraction. Moreover, alterations in calcium management are the main factors c...

Due to the limitations of current in vivo experimental designs, our comprehensive knowledge of vascular development and its implications for the development of large-scale engineered tissue constructs is very limited. Therefore, the purpose of this s...

Brain diseases including Down syndrome (DS/TS21) are known to be characterized by changes in cellular metabolism. To adequately assess such metabolic changes during pathological processes and to test drugs, methods are needed that allow monitoring of...

The objective of this study was to assess changes in the echogenicity of the cortex and medulla of canine fetal kidneys in relation to days before parturition (dbp), maternal size and litter size. Monitoring of 10 healthy pregnant bitches (2–8...

Despite the extensive and rapidly growing literature on microplastics in oceans and coastal seas, little information exists on microplastic distribution through the salinity gradient. This study is the first one to evaluate microplastic distribution...

In the field of histological analysis, one of the typical issues is the analysis of single cells contained in regions of interest (i.e., ROIs). Today, several commercial, freely available, and open-source software options are accessible for this task...

Glioblastoma (GBM) is highly resistant to treatment and invasion into the surrounding brain is a cancer hallmark that leads to recurrence despite surgical resection. With the emergence of precision medicine, patient-derived 3D systems are considered...

Objective: This study aimed to evaluate peri-implant tissue changes during early osseointegration using a combined approach of digital radiographic analysis, RGB pseudocolorization, and histomorphometry in a sheep tibia model. Materials and Methods:...

Meibomian gland dysfunction (MGD), a chronic abnormality of meibomian glands, causes various dry eye symptoms. Principal treatments for MGD are warm compression and mechanical squeezing of the eyelids. In this study, the immediate impact of this trea...

After tooth extraction, resorptive changes in extraction sockets and the adjacent alveolar ridge can affect subsequent tooth replacement and implantation. Several surgical concepts, including the application of autologous blood concentrate platelet-r...

Microglia are involved in the post-stroke immunomodulation of brain plasticity, repair, and reorganization. Here, we evaluated whether adipose-tissue-derived mesenchymal stem cells (ADMSCs) and/or rehabilitation improve behavioral recovery by modulat...