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37 Results Found

  • Article
  • Open Access
11 Citations
3,563 Views
28 Pages

24 August 2021

This work extends the investigation of higher-order sensitivity and uncertainty analysis from 3rd-order to 4th-order for a polyethylene-reflected plutonium (PERP) OECD/NEA reactor physics benchmark. Specifically, by applying the 4th-order comprehensi...

  • Feature Paper
  • Article
  • Open Access
18 Citations
3,131 Views
34 Pages

5 November 2019

This work presents the Third-Order Adjoint Sensitivity Analysis Methodology (3rd-ASAM) for response-coupled forward and adjoint linear systems. The 3rd-ASAM enables the efficient computation of the exact expressions of the 3rd-order functional deriva...

  • Article
  • Open Access
13 Citations
2,442 Views
42 Pages

10 December 2021

This work presents the mathematical framework of the nth-Order Comprehensive Adjoint Sensitivity Analysis Methodology for Response-Coupled Forward/Adjoint Linear Systems (abbreviated as “nth-CASAM-L”), which is conceived for obtaining the...

  • Review
  • Open Access
6 Citations
2,125 Views
53 Pages

15 October 2021

This work reviews the state-of-the-art methodologies for the deterministic sensitivity analysis of nonlinear systems and deterministic quantification of uncertainties induced in model responses by uncertainties in the model parameters. The need for c...

  • Article
  • Open Access
5 Citations
2,980 Views
16 Pages

21 January 2022

This work quantifies the impact of the most important 4th-order sensitivities of the leakage response of a polyethylene-reflected plutonium (PERP) reactor physics benchmark with respect to the benchmark’s 180 group-averaged microscopic total cr...

  • Article
  • Open Access
3 Citations
4,123 Views
11 Pages

This paper presents the FEM modeling and simulation of a thin-film bulk acoustic resonator (FBAR) for a tetrachloroethene (PCE) gas-sensing application. A zinc oxide layer is used as a piezoelectric material; an aluminum layer is used as the electrod...

  • Article
  • Open Access
954 Views
23 Pages

16 April 2025

The gear-transmission system plays a crucial role in power transmission for urban railway vehicles. However, it can experience abnormal meshing conditions due to wheel polygonization, which presents a potential safety hazard for vehicle operations. T...

  • Article
  • Open Access
6 Citations
3,195 Views
10 Pages

7-Tesla Functional Cardiovascular MR Using Vectorcardiographic Triggering—Overcoming the Magnetohydrodynamic Effect

  • Christian Hamilton-Craig,
  • Daniel Stäeb,
  • Aiman Al Najjar,
  • Kieran O’Brien,
  • William Crawford,
  • Sabine Fletcher,
  • Markus Barth and
  • Graham Galloway

4 August 2021

Objective: Ultra-high-field B0 ≥ 7 tesla (7T) cardiovascular magnetic resonance (CMR) offers increased resolution. However, electrocardiogram (ECG) gating is impacted by the magneto-hydrodynamic effect distorting the ECG trace. We explored the techni...

  • Article
  • Open Access
2 Citations
2,752 Views
33 Pages

24 February 2022

This work illustrates the application of the fourth-order comprehensive sensitivity analysis methodology for nonlinear systems (abbreviated as “4th-CASAM-N”), which enables the efficient computation of exactly determined 1st-, 2nd-, 3rd-,...

  • Article
  • Open Access
5 Citations
6,993 Views
14 Pages

5 December 2014

One of the most important goals in proteomics is to detect the real-time kinetics of diverse biomolecular interactions. Fluorescence, which requires extrinsic tags, is a commonly and widely used method because of its high convenience and sensitivity....

  • Article
  • Open Access
12 Citations
2,790 Views
45 Pages

6 June 2021

The most general quantities of interest (called “responses”) produced by the computational model of a linear physical system can depend on both the forward and adjoint state functions that describe the respective system. This work presents the Fourth...

  • Article
  • Open Access
2 Citations
1,549 Views
17 Pages

An Option Game Model of Supplier R&D Co-Competition under Uncertainty

  • Yinghua Song,
  • Xiaoyan Sang,
  • Zhe Wang and
  • Hongqian Xu

14 August 2023

In order to improve the market competitiveness of suppliers and their resilience to emergencies, it is of great significance to discuss the investment decision making of suppliers in developing new products under uncertain and competitive environment...

  • Article
  • Open Access
18 Citations
4,389 Views
13 Pages

The Influence of Temperature Changes on the Rice Starch Structure and Digestive Characteristics: One and Two-Step Annealing

  • Guiyuan Xiang,
  • Jiangtao Li,
  • Wenfang Han,
  • Yaqin Yang,
  • Qinlu Lin,
  • Ying Yang,
  • Qiongxiang Liu,
  • Xiaofeng Guo,
  • Qianru Pan and
  • Lingxue Cao
  • + 1 author

14 November 2022

This study investigated the effects of annealing on the structural and physicochemical properties of rice starch below the onset temperature (To) by 5 °C and 15 °C. The results revealed that annealing improved the gelatinization temperature o...

  • Article
  • Open Access
1 Citations
2,203 Views
31 Pages

30 June 2022

The application of the recently developed “nth-order comprehensive sensitivity analysis methodology for nonlinear systems” (abbreviated as “nth-CASAM-N”) has been previously illustrated on paradigm nonlinear space-dependent pr...

  • Article
  • Open Access
8 Citations
3,136 Views
23 Pages

24 September 2023

The design of a low-pass-frequency filter with the electronic change of the approximation characteristics of resulting responses is presented. The filter also offers the reconnection-less reconfiguration of the order (1st-, 2nd-, 3rd- and 4th-order f...

  • Article
  • Open Access
2 Citations
2,728 Views
15 Pages

CIRCNV: Detection of CNVs Based on a Circular Profile of Read Depth from Sequencing Data

  • Hai-Yong Zhao,
  • Qi Li,
  • Ye Tian,
  • Yue-Hui Chen,
  • Haque A. K. Alvi and
  • Xi-Guo Yuan

25 June 2021

Copy number variation (CNV) is a common type of structural variation in the human genome. Accurate detection of CNVs from tumor genomes can provide crucial information for the study of tumor genesis and cancer precision diagnosis. However, the contam...

  • Article
  • Open Access
30 Citations
3,519 Views
15 Pages

The NUMEN Project: Toward New Experiments with High-Intensity Beams

  • Clementina Agodi,
  • Antonio D. Russo,
  • Luciano Calabretta,
  • Grazia D’Agostino,
  • Francesco Cappuzzello,
  • Manuela Cavallaro,
  • Diana Carbone,
  • Paolo Finocchiaro,
  • Luciano Pandola and
  • Federico Pinna
  • + 6 authors

The search for neutrinoless double-beta (0νββ) decay is currently a key topic in physics, due to its possible wide implications for nuclear physics, particle physics, and cosmology. The NUMEN project aims to provide experimental information on the nu...

  • Article
  • Open Access
7 Citations
9,263 Views
14 Pages

Low-Cost Photolithographic Fabrication of Nanowires and Microfilters for Advanced Bioassay Devices

  • Nhi M. Doan,
  • Liangliang Qiang,
  • Zhe Li,
  • Santhisagar Vaddiraju,
  • Gregory W. Bishop,
  • James F. Rusling and
  • Fotios Papadimitrakopoulos

12 March 2015

Integrated microfluidic devices with nanosized array electrodes and microfiltration capabilities can greatly increase sensitivity and enhance automation in immunoassay devices. In this contribution, we utilize the edge-patterning method of thin alumi...

  • Article
  • Open Access
3 Citations
3,985 Views
14 Pages

30 March 2020

To better understand the potential presence of light element alloys of Fe and Ni in the Earth’s interior, the crystal structure and compressional behavior of the Ni-P binary compound, schreibersite (Ni3P), have been investigated using synchrotr...

  • Article
  • Open Access
7 Citations
4,746 Views
19 Pages

3 January 2020

We report on a novel RNA virus infecting the wasp Lysiphlebus fabarum, a parasitoid of aphids. This virus, tentatively named “Lysiphlebus fabarum virus” (LysV), was discovered in transcriptome sequences of wasps from an experimental evolu...

  • Article
  • Open Access
5 Citations
2,688 Views
15 Pages

30 May 2022

Emerging evidence suggests that poor mental health is particularly pronounced among Chinese residents, who are exposed to nearly the worst air pollution worldwide. However, the correlations between air pollutant concentration and mental health have n...

  • Article
  • Open Access
8 Citations
4,029 Views
23 Pages

2 August 2020

The asymmetric faults often cause the power grid current imbalance and power grid oscillation, which brings great instability risk to the power grid. To address this problem, this paper presented a modeling and parameter optimization method of grid-c...

  • Article
  • Open Access
17 Citations
5,381 Views
17 Pages

24 August 2022

Mean and Median frequency are typically used for detecting and monitoring muscle fatigue. These parameters are extracted from power spectral density whose estimate can be obtained by several techniques, each one characterized by advantages and disadv...

  • Article
  • Open Access
8 Citations
3,770 Views
17 Pages

(1) Background: Years of life lost (YLL) as a surrogate of health is important for supporting ambient air pollution related policy decisions. However, there has been little comprehensive evaluation of the short-term impact of air pollution on cause-s...

  • Article
  • Open Access
7 Citations
3,109 Views
14 Pages

Sponge Whirl-Pak Sampling Method and Droplet Digital RT-PCR Assay for Monitoring of SARS-CoV-2 on Surfaces in Public and Working Environments

  • Davide Cardinale,
  • Maria Tafuro,
  • Andrea Mancusi,
  • Santa Girardi,
  • Federico Capuano,
  • Yolande Thérèse Rose Proroga,
  • Federica Corrado,
  • Jacopo Luigi D’Auria,
  • Annachiara Coppola and
  • Maria Morgante
  • + 8 authors

The SARS-CoV-2 can spread directly via saliva, respiratory aerosols and droplets, and indirectly by contact through contaminated objects and/or surfaces and by air. In the context of COVID-19 fomites can be an important vehicle of virus transmission...

  • Abstract
  • Open Access
1,957 Views
1 Page

Real-time molecular techniques have become the reference methods for the direct diagnosis of pathogens. The reduction of steps is a key factor in order to decrease the risk of human errors resulting in invalid series and delayed results. We describe...

  • Proceeding Paper
  • Open Access
1,685 Views
6 Pages

Development of a Clock Generation and Time Distribution System for Hyper-Kamiokande

  • Lucile Mellet,
  • Mathieu Guigue,
  • Boris Popov,
  • Stefano Russo and
  • Vincent Voisin

The construction of the next-generation water Cherenkov detector Hyper-Kamiokande (HK) has started. It will have about a ten times larger fiducial volume compared to the existing Super-Kamiokande detector, as well as increased detection performances....

  • Article
  • Open Access
20 Citations
3,083 Views
16 Pages

7 May 2021

Machined surface integrity characteristics, including surface stresses, physical-mechanical properties and metallographic structures, play important roles in the fatigue performance of machined components. This work aimed at investigating the effects...

  • Article
  • Open Access
10 Citations
3,180 Views
19 Pages

Performance of Fully Automated Algorithm Detecting Bone Marrow Edema in Sacroiliac Joints

  • Joanna Ożga,
  • Michał Wyka,
  • Agata Raczko,
  • Zbisław Tabor,
  • Zuzanna Oleniacz,
  • Michał Korman and
  • Wadim Wojciechowski

24 July 2023

This study evaluates the performance of a fully automated algorithm to detect active inflammation in the form of bone marrow edema (BME) in iliac and sacral bones, depending on the quality of the coronal oblique plane in patients with axial spondyloa...

  • Article
  • Open Access
3 Citations
2,768 Views
15 Pages

Novel Proteome Targets Marking Insulin Resistance in Metabolic Syndrome

  • Moritz V. Warmbrunn,
  • Harsh Bahrar,
  • Nicolien C. de Clercq,
  • Annefleur M. Koopen,
  • Pieter F. de Groot,
  • Joost Rutten,
  • Leo A. B. Joosten,
  • Ruud S. Kootte,
  • Kristien E. C. Bouter and
  • Max Nieuwdorp
  • + 11 authors

10 June 2024

Context/Objective: In order to better understand which metabolic differences are related to insulin resistance in metabolic syndrome (MetSyn), we used hyperinsulinemic–euglycemic (HE) clamps in individuals with MetSyn and related peripheral ins...

  • Article
  • Open Access
20 Citations
6,371 Views
23 Pages

The BCAT1 CXXC Motif Provides Protection against ROS in Acute Myeloid Leukaemia Cells

  • James Hillier,
  • Gemma J. Allcott,
  • Laura A. Guest,
  • Wayne Heaselgrave,
  • Alex Tonks,
  • Myra E. Conway,
  • Amy L. Cherry and
  • Steven J. Coles

The cytosolic branched-chain aminotransferase (BCAT1) has received attention for its role in myeloid leukaemia development, where studies indicate metabolic adaptations due to BCAT1 up-regulation. BCAT1, like the mitochondria isoform (BCAT2), shares...

  • Article
  • Open Access
4 Citations
2,287 Views
22 Pages

1 July 2023

High-speed maneuvering target inverse synthetic aperture radar (ISAR) imaging is always a hot topic in signal processing. High-speed maneuvering targets often have high-order maneuvering characteristics, such as translational and rotational character...

  • Article
  • Open Access
7 Citations
2,464 Views
16 Pages

FvMYB108, a MYB Gene from Fragaria vesca, Positively Regulates Cold and Salt Tolerance of Arabidopsis

  • Penghui Song,
  • Ruihua Yang,
  • Kuibao Jiao,
  • Baitao Guo,
  • Lei Zhang,
  • Yuze Li,
  • Kun Zhang,
  • Shuang Zhou,
  • Xinjuan Wu and
  • Xingguo Li

MYB (myoblast) protein comes in large quantities and a wide variety of types and plays a role in most eukaryotes in the form of transcription factors (TFs). One of its important functions is to regulate plant responses to various stresses. However, t...

  • Article
  • Open Access
239 Views
24 Pages

13 March 2026

This study presents a quantitative, scenario-based framework for analyzing humanity’s potential progression along the Kardashev scale, with emphasis on the transition to Type I (planetary-scale) and Type II (stellar-scale) civilization status....

  • Article
  • Open Access
7 Citations
2,952 Views
23 Pages

All-People-Test-Based Methods for COVID-19 Infectious Disease Dynamics Simulation Model: Towards Citywide COVID Testing

  • Xian-Xian Liu,
  • Jie Yang,
  • Simon Fong,
  • Nilanjan Dey,
  • Richard C. Millham and
  • Jinan Fiaidhi

The conversion rate between asymptomatic infections and reported/unreported symptomatic infections is a very sensitive parameter for model variables that spread COVID-19. This is important information for follow-up use in screening, prediction, progn...

  • Article
  • Open Access
11 Citations
5,294 Views
26 Pages

JPSS VIIRS SST Reanalysis Version 3

  • Olafur Jonasson,
  • Alexander Ignatov,
  • Victor Pryamitsyn,
  • Boris Petrenko and
  • Yury Kihai

20 July 2022

The 3rd full-mission reanalysis (RAN3) of global sea surface temperature (SST) with a 750 m resolution at nadir is available from VIIRS instruments flown onboard two JPSS satellites: NPP (February 2012–present) and N20 (January 2018–prese...

  • Article
  • Open Access
3 Citations
2,905 Views
16 Pages

CA 19-9 but Not IGF-1/IGFBP-2 Is a Useful Biomarker for Pancreatic Ductal Adenocarcinoma (PDAC) and Chronic Pancreatitis (CP) Differentiation

  • Barbara Wlodarczyk,
  • Lukasz Durko,
  • Przemyslaw Wlodarczyk,
  • Renata Talar-Wojnarowska and
  • Ewa Malecka-Wojciesko

14 June 2023

Introduction: There are still no effective diagnostic and prognostic biomarkers in pancreatic ductal adenocarcinoma (PDAC). The differentiation between PDAC and chronic pancreatitis (CP) is often challenging. The inflammatory mass in the course of CP...