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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Advances in Cardiac Imaging
edited by
submission deadline 20 Jul 2025 | 3 articles | Viewed by 4382 | Submission Open
Keywords: non-invasive imaging; heart; vessels; application; diagnosis; technique
(This special issue belongs to the Section Cardiology)
Clinical Diagnosis and Management of Neonatal Diseases
edited by Ayala Gover and
submission deadline 20 Jul 2025 | 5 articles | Viewed by 2885 | Submission Open
Keywords: newborn; preterm; neonatal intensive care; low birth weight; point-of-care ultrasound; neonatal monitoring
(This special issue belongs to the Section Clinical Pediatrics)
New Advances in Cardiovascular Diseases: The Cutting Edge
edited by
submission deadline 20 Jul 2025 | 1 articles | Viewed by 1882 | Submission Open
Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Hypertension and Related Complications submission deadline 20 Jul 2025 | 1 articles | Viewed by 1789 | Submission Open
Keywords: hypertension; hypertensive disorders of pregnancy; antihypertensive therapy; resistant hypertension; dual endothelin receptor antagonist; renal denervation; cardiovascular risk; adherence; kidney disease; secondary hypertension
(This special issue belongs to the Section Cardiovascular Medicine)
Long COVID and Cardiovascular Health: Clinical Perspectives on Risk and Management
edited by Mariana Tudoran and
submission deadline 20 Jul 2025 | 2 articles | Viewed by 1360 | Submission Open
Keywords: long COVID; cardiovascular disease; long COVID therapy; management of long COVID; mechanisms of long COVID
(This special issue belongs to the Section Cardiovascular Medicine)
Current Situation and Challenges of Endovascular Treatment Strategies for Acute Ischemic Stroke
edited by
submission deadline 20 Jul 2025 | 1 articles | Viewed by 1056 | Submission Open
Keywords: acute ischemic stroke; endovascular treatment; imaging; management of ischemic stroke; system and strategy for acute ischemic stroke; multidisciplinary approach for acute ischemic stroke
(This special issue belongs to the Section Clinical Neurology)
Advances in Tuberculosis: Comprehensive Insights and Management Strategies
edited by Aliaksandr Skrahin
submission deadline 20 Jul 2025 | 1 articles | Viewed by 866 | Submission Open
Keywords: pulmonary and extra-pulmonary tuberculosis (TB); TB epidemiology; TB screening; TB prevention; TB diagnostics; TB treatment; TB co-infections (e.g.; HIV; Hepatitis B and C); TB co-morbidities (e.g.; diabetes); host and Mycobacteria genetic; molecular mechanisms and genotype/phenotype correlations
(This special issue belongs to the Section Infectious Diseases)
Clinical Management of Cardiogenic Shock and Cardiac Arrest: 2nd Edition
edited by Jaime A. Hernández-Montfort
submission deadline 20 Jul 2025 | 1 articles | Viewed by 722 | Submission Open
Keywords: cardiogenic shock; cardiac arrest; temporary mechanical circulatory support; ECMO; transitions; heart recovery; heart replacement
(This special issue belongs to the Section Cardiology)
Clinical Comparisons of Nonpharmaceutical and Pharmaceutical Analgesia
edited by and
submission deadline 20 Jul 2025 | Viewed by 217 | Submission Open
Keywords: acute pain; chronic pain; postoperative pain; non-pharmaceutical; pharmaceutical; analgesia; clinical
(This special issue belongs to the Section Anesthesiology)
New Technologies in Neurosurgery: An Insight into the Future
edited by Ismail Zaed
submission deadline 23 Jul 2025 | Viewed by 300 | Submission Open
Keywords: neurosurgery; training; technology; augmented reality; virtual reality; robot
(This special issue belongs to the Section Clinical Neurology)
Future Trends in the Diagnosis and Management of Celiac Disease submission deadline 24 Jul 2025 | 3 articles | Viewed by 4723 | Submission Open
Keywords: celiac disease; gluten; autoimmune disease; extraintestinal manifestations; serologic diagnosis; gluten-free diet
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Artificial Intelligence (AI)-Based Diagnosis in Clinical Practice
edited by
submission deadline 24 Jul 2025 | 3 articles | Viewed by 4256 | Submission Open
Keywords: artificial intelligence; AI; diagnosis; clinical medicine; practice
(This special issue belongs to the Section Epidemiology & Public Health)
Clinical Treatment of Refractory Full Thickness Macular Hole (FTMH)
edited by
submission deadline 24 Jul 2025 | 1 articles | Viewed by 659 | Submission Open
Keywords: refractory full thickness macular hole; pars plana vittectomy; internal limiting membrane; peeling; tamponade; flap
(This special issue belongs to the Section Ophthalmology)
Clinical Updates on Maternal Fetal Medicine submission deadline 25 Jul 2025 | 8 articles | Viewed by 16410 | Submission Open
Keywords: diabetes in pregnancy; hypertension in pregnancy; cholestasis in pregnancy; endocrine disorder in pregnancy; sepsis in pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Gynecological Surgery: New Clinical Insights and Challenges
edited by Francesco Plotti
submission deadline 25 Jul 2025 | 9 articles | Viewed by 11319 | Submission Open
Keywords: minimally invasive surgery; urogynecologic surgery; complications; gynecologic oncology; robotic surgery; benign gynecologic surgery; vaginal surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Debates in Minimally Invasive Glaucoma Surgery (MIGS)
edited by
submission deadline 25 Jul 2025 | 9 articles | Viewed by 9182 | Submission Open
Keywords: MIGS (minimally invasive glaucoma surgery); schlemm’ s canal opening surgery; trabeculotomy; trabeculectomy; collector channel; histology; intraocular pressure; surgical success
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Hemodialysis
edited by Maurizio Bossola
submission deadline 25 Jul 2025 | 7 articles | Viewed by 7067 | Submission Open
Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy
(This special issue belongs to the Section Nephrology & Urology)
Clinical Perspectives in Trauma and Orthopedic Surgery
edited by
submission deadline 25 Jul 2025 | 4 articles | Viewed by 5078 | Submission Open
Keywords: trauma; sports; ankle; knee; hip; cartilage regeneration; bone regeneration; orthopedic surgery
(This special issue belongs to the Section Orthopedics)
Chronic Complications of Type 2 Diabetes: Prevalence, Prevention, and Management
edited by
submission deadline 25 Jul 2025 | 4 articles | Viewed by 4627 | Submission Open
Keywords: pathogenesis of diabetic complications; epidemiology of diabetic complications; diabetic retinopathy; diabetic chronic kidney disease; diabetes neuropathies; coronary heart disease; peripheral vascular disease; hypertension and dyslipidemia in diabetes
(This special issue belongs to the Section Endocrinology & Metabolism)
Thoracic Imaging in Cardiovascular and Pulmonary Disease Diagnosis
edited by Marco Sperandeo and
submission deadline 25 Jul 2025 | 3 articles | Viewed by 4570 | Submission Open
Keywords: thoracic imaging; cardiovascular diagnosis; pulmonary disease; clinical medicine; diagnostic accuracy; imaging techniques; thoracic ultrasound; patient care
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Foot and Ankle Surgery: State of the Art and Future Perspectives
edited by Sung Jae Kim and Jaehwang Song
submission deadline 25 Jul 2025 | 5 articles | Viewed by 3725 | Submission Open
Keywords: foot and ankle surgery; hallux disorders; lesser toe problem; diabetic foot salvage; calcaneal fracture; pilon fracture; ligament disorder
(This special issue belongs to the Section Orthopedics)
Applied Cardiorespiratory Physiology in Critical Care Medicine
edited by and Paraskevi Tselioti
submission deadline 25 Jul 2025 | 1 articles | Viewed by 2986 | Submission Open
Keywords: applied physiology; critical care medicine; cardiovascular physiology; respiratory physiology
(This special issue belongs to the Section Anesthesiology)
Multiple Myeloma: Advances in Diagnosis and Treatment
edited by
submission deadline 25 Jul 2025 | 1 articles | Viewed by 2616 | Submission Open
Keywords: multiple myeloma; early intervention; novel therapies; treatment approach; prognosis; bispecific antibodies; CAR T-cells
(This special issue belongs to the Section Oncology)
Vasculitis in Adults and Children: Symptoms, Diagnosis and Treatment—2nd Edition
edited by
submission deadline 25 Jul 2025 | 1 articles | Viewed by 1961 | Submission Open
Keywords: vasculitis; glucocorticoids; cyclophosphamide; molecularly targeted therapy; unmet clinical needs; potential therapeutic targets
(This special issue belongs to the Section Vascular Medicine)
Innovative Clinical Approaches in Oral Health Prevention and Management
edited by , and Flavia Vitiello
submission deadline 25 Jul 2025 | 2 articles | Viewed by 1845 | Submission Open
Keywords: oral health; oral prevention; teeth remineralization; oral pathology; oral health management; preventive dentistry; translational dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Accelerating Fracture Healing: Clinical Diagnosis and Treatment
edited by Seong-Eun Byun
submission deadline 25 Jul 2025 | 3 articles | Viewed by 1674 | Submission Open
Keywords: fracture; fracture surgery; fracture healing; diagnosis; treatment
(This special issue belongs to the Section Orthopedics)
Clinical Updates in Cardiac Electrophysiology: 2nd Edition
edited by Kenneth C. Bilchick
submission deadline 25 Jul 2025 | 1 articles | Viewed by 1566 | Submission Open
Keywords: arrhythmias; atrial fibrillation; cardiac electrophysiology; heart rhythm disorders; ablation; ventricular tachycardia; remote monitoring; digital health; artificial intelligence; cardiac magnetic resonance
(This special issue belongs to the Section Cardiology)
Clinical Risks and Perinatal Outcomes in Pregnancy and Childbirth: 2nd Edition
edited by Apostolos Mamopoulos and
submission deadline 25 Jul 2025 | 2 articles | Viewed by 1408 | Submission Open
Keywords: pregnancy complications; perinatal outcomes; childbirth; hypertension; diabetes; fetal growth restriction; stillbirth; preterm delivery
(This special issue belongs to the Section Obstetrics & Gynecology)
Optimizing Present and Future Therapeutic Choices for Treatment and Management of Chronic Inflammatory Bowel Diseases—2nd Edition
edited by
submission deadline 25 Jul 2025 | 1 articles | Viewed by 1342 | Submission Open
Keywords: Inflammatory Bowel Diseases(IBD); JAK inhibitors; mucosal healing
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Safety in Spinal Surgery
edited by Simon B. Roberts and
submission deadline 25 Jul 2025 | 1 articles | Viewed by 1191 | Submission Open
Keywords: spinal surgery; patients with spinal deformity; inherent risks; risk management; surgery safety
(This special issue belongs to the Section General Surgery)
The Role of Biomarkers in Cardiovascular Diseases
edited by Giorgia Panichella
submission deadline 25 Jul 2025 | 1 articles | Viewed by 890 | Submission Open
Keywords: biomarkers; cardiovascular diseases; heart failure; ischemic heart disease; cardiomyopathy; risk stratification; diagnosis; prognosis; inflammation
(This special issue belongs to the Section Cardiovascular Medicine)
Inflammatory Bowel Diseases: Clinical Advances and Emerging Therapies submission deadline 25 Jul 2025 | 1 articles | Viewed by 845 | Submission Open
Keywords: inflammatory bowel disease (IBD); ulcerative colitis; Crohn’ s disease; gut inflammation; bowel perforation
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
New Clinical Treatment for Ocular Vascular Disease and Fundus Disease: Second Edition
edited by , Shohista Saidkasimova and
submission deadline 25 Jul 2025 | 1 articles | Viewed by 793 | Submission Open
Keywords: ocular vascular diseases; fundus disorders; diabetic retinopathy; retinal vein occlusion; age-related macular degeneration; retinal detachment
(This special issue belongs to the Section Ophthalmology)
Diagnosis and Management of Aortic Diseases: Drafting from Theoretical Aspects to Clinical Practice—2nd Edition
edited by
submission deadline 25 Jul 2025 | 1 articles | Viewed by 783 | Submission Open
Keywords: aortic disease; aortic aneurysm; aortic dissection; aortic surgery; diagnosis and management
(This special issue belongs to the Section Cardiovascular Medicine)
Advances and Trends in Pediatric Surgery submission deadline 25 Jul 2025 | 1 articles | Viewed by 683 | Submission Open
Keywords: pediatric surgery; minimally invasive surger; robotics; trends; advances
(This special issue belongs to the Section Clinical Pediatrics)
Minimally Invasive Gynecological Surgery: State of the Art and the Perspectives
edited by Artur Jakimiuk
submission deadline 25 Jul 2025 | 1 articles | Viewed by 657 | Submission Open
Keywords: robotic surgery; laparoscopy; hysteroscopy; gynecological oncolgy surgery; minimally invasive gynecological procedures; reproductive endocrinology; urinary incontinence; endometriosis; advance laparoscopic surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Interventional Cardiology—Challenges and Solutions
edited by
submission deadline 25 Jul 2025 | 1 articles | Viewed by 570 | Submission Open
Keywords: chronic total occlusion; highly calcified coronary or lower extremity arteries; stentless percutaneous coronary intervention; chronic limb threatening ischemia; instent restenosis in the extremity artery diseases; endovascular therapy for pulmonary thromboembolism; transcatheter aortic valve replacemment for the bicuspid aortic valve; transcatheter aortic valve replacement for the valve-in-valve procedure; endovascular therapy for tricospid valve regurgitation; transcatheter edge-to-edge repair for mitral valve regurgitation
(This special issue belongs to the Section Cardiovascular Medicine)
New Perspectives in Chronic Kidney Disease, Transplantation and Immune System
edited by and Dimitrios A. Tsakiris
submission deadline 25 Jul 2025 | 1 articles | Viewed by 525 | Submission Open
Keywords: kidney transplantation; HLA; matching at the epitope level; DSAs; complement; kidney disease epigenetics; diabetic nephropathy; hemostasis; graft rejection; B and T cell immunophenotyping; end stage renal disease
(This special issue belongs to the Section Nephrology & Urology)
Advances in the Field of Cutaneous Malignancies: Background and Clinical Management submission deadline 25 Jul 2025 | Viewed by 396 | Submission Open
Keywords: dermatology; skin cancer; diagnosis; melanoma; basal cell carcinoma; squamous cell carcinoma; imaging; artificial intelligence; dermoscopy; treatment
(This special issue belongs to the Section Dermatology)
Clinical Advances in Genetic Obesity and Health submission deadline 25 Jul 2025 | Viewed by 355 | Submission Open
Keywords: obesity; genetics; health; nutrigenetics; clinical trials; personalized
(This special issue belongs to the Section Endocrinology & Metabolism)
Hepatobiliary Surgery: State of the Art and Future Perspectives
edited by and
submission deadline 25 Jul 2025 | Viewed by 229 | Submission Open
Keywords: hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; benign liver lesions
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates on Cardiac Electrophysiology
edited by Roberto Rordorf
submission deadline 25 Jul 2025 | Viewed by 187 | Submission Open
Keywords: percutaneous cardiac ablation; surgical cardiac ablation; atrial fibrillation; ventricula tachycardia; non invasive radiotherapy of cardiac arrhythmias; neuromodulation of cardiac arrhythmias
(This special issue belongs to the Section Cardiology)
Innovations in Coronary Artery Disease Treatment and Prevention
edited by
submission deadline 25 Jul 2025 | Viewed by 179 | Submission Open
Keywords: coronary artery disease (CAD); CAD prevention and treatment innovations; CAD biomarkers and imaging; advanced imaging and diagnostics; personalized medicine in cardiology; predictive analytics in CAD
(This special issue belongs to the Section Cardiovascular Medicine)
Robotic-Assisted Colorectal Surgery: Advancements and Clinical Applications submission deadline 25 Jul 2025 | Viewed by 157 | Submission Open
Keywords: rectal cancer; diverticulitis; hemicolectomy; redo surgery; cost-effectiveness
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Hysteroscopic Technology for Gynecological Diseases
edited by Aya Mohr-Sasson and Raanan Meyer
submission deadline 25 Jul 2025 | Viewed by 152 | Submission Open
Keywords: diagnostic hysteroscopy; operative hysteroscopy; uterine sampling; uterine polyp; submucosal fibroid; hysteroscopic dilatation and curettage; hysteroscopic niche repair
(This special issue belongs to the Section Obstetrics & Gynecology)
Gestational Diabetes: Cutting-Edge Research and Clinical Practice
edited by Vendula Bartakova
submission deadline 26 Jul 2025 | 3 articles | Viewed by 2972 | Submission Open
Keywords: gestational diabetes mellitus; oral glucose tolerance test; treatment; pregnancy; peripartal outcomes
(This special issue belongs to the Section Endocrinology & Metabolism)
Research Progress and Challenges in Acute Abdominal Surgery
edited by Matteo Cimino
submission deadline 26 Jul 2025 | 1 articles | Viewed by 1627 | Submission Open
Keywords: acute abdominal emergencies; urgent surgical interventions; minimally invasive techniques; robotic surgery in emergency surgery; open surgery; complications; pain management; postoperative rehabilitation; acute appendicitis; acute biliary disease; intraoperative ultrasonography in emergency surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardiac Surgery: Innovations, Challenges and Opportunities
edited by Kyriakos Spiliopoulos and Keti Vitanova
submission deadline 28 Jul 2025 | Viewed by 416 | Submission Open
Keywords: minimally invasive cardiac surgery; redo cardiac surgery; transcatheter aortic valve implantation (TAVI); advances in mechanical circulatory support; endo-carditis; aortic surgery
(This special issue belongs to the Section Cardiology)
Peritoneal Dialysis—Procedure, Risks, Results submission deadline 28 Jul 2025 | Viewed by 248 | Submission Open
Keywords: peritoneal dialysis; peritoneal catheter placement; peritoneal dialysis outcomes; peritoneal membrane; peritoneal transport; infectious complications; mechanical complications; nutritional status; volume management; peritoneal dialysis solutions
(This special issue belongs to the Section Nephrology & Urology)
Clinical Challenges and Advances in Oncology Radiology
edited by Ammar A Chaudhry
submission deadline 28 Jul 2025 | Viewed by 146 | Submission Open
Keywords: radiomics; theranostics; oncology; targeted therapies; immuno-oncology
(This special issue belongs to the Section Oncology)
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