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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Traumatic Brain Injury: Clinical Diagnosis and Management
edited by Alessio Caccioppola
submission deadline 15 Jun 2026 | 1 articles | Viewed by 1207 | Submission Open
Keywords: glasgow coma scale; intracranial pressure monitoring; traumatic brain injury; diffuse axonal injury; post-traumatic epilepsy; decompressive craniectomy; neuromonitoring
(This special issue belongs to the Section Brain Injury)
Clinical Diagnosis and Management of Erectile Dysfunction
edited by Maurizio De Rocco Ponce and
submission deadline 15 Jun 2026 | 1 articles | Viewed by 1163 | Submission Open
Keywords: erectile dysfunction; clinical management; cardiovascular disease; penile prosthesis; personalized medicine; hipogonadism
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Cardiac Arrest: Strategies, Innovations, and Improvements in Outcomes
edited by
submission deadline 15 Jun 2026 | Viewed by 1146 | Submission Open
Keywords: cardiac arrest; cardiopulmonary resuscitation; post-cardiac arrest syndrome; neurological outcomes
(This special issue belongs to the Section Cardiology)
Advances in Minimally Invasive Cardiothoracic Surgery: Current Techniques and Future Innovations submission deadline 15 Jun 2026 | 2 articles | Viewed by 1097 | Submission Open
Keywords: cardiothoracic surgery; lung cancer; cardiac imaging; minimally invasive surgery; thoracic oncology
(This special issue belongs to the Section Cardiovascular Medicine)
Aortic Surgery: State of the Art and Future Directions submission deadline 15 Jun 2026 | 2 articles | Viewed by 780 | Submission Open
Keywords: aortic surgery; aortic aneurysm; aortic dissection; aortic arch; biomaterials; endovascular approach; FET; TEVAR
(This special issue belongs to the Section Cardiovascular Medicine)
Innovations in Infertility Treatment and Assisted Reproductive Technologies (ARTs)
edited by Diana Alecsandru
submission deadline 15 Jun 2026 | Viewed by 529 | Submission Open
Keywords: infertility; assisted reproductive technology (ARTs); fertility preservation; in vitro fertilization (IVF); reproductive endocrinology
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Advancements in Foot and Ankle Surgery: 2nd Edition
edited by
submission deadline 15 Jun 2026 | 1 articles | Viewed by 364 | Submission Open
Keywords: flat foot; hindfoot motion; diabetic foot; hallux valgus; foot infection; foot trauma
(This special issue belongs to the Section Orthopedics)
Current Challenges and Opportunities in Assisted Reproductive Technologies
edited by Andrea Milostić-Srb and
submission deadline 15 Jun 2026 | Viewed by 356 | Submission Open
Keywords: artificial reproductive technologies; ART; mental health effect on ART; IVF; AI in reproductive medicine
(This special issue belongs to the Section Obstetrics & Gynecology)
Surgical Management of Vascular Diseases: Challenges and Innovations in the 21st Century
edited by Reinhardt T. Grundmann
submission deadline 15 Jun 2026 | Viewed by 285 | Submission Open
Keywords: abdominal aortic aneurysm; carotid stenosis; peripheral vascular disease; endovascular therapy; open surgery; vascular disease and cancer outcomes; clinical trial; meta-analysis; surgical innovation
(This special issue belongs to the Section Cardiovascular Medicine)
Skin Cancer: From Diagnosis to Personalized Treatment
edited by
submission deadline 15 Jun 2026 | Viewed by 258 | Submission Open
Keywords: immunotherapy; neoadjuvant; melanoma; cutaneous sarcoma; merkel cel tumor; risk assessment; combination therapy; surgery
(This special issue belongs to the Section Dermatology)
New Advances in Stereotactic Radiosurgery
edited by Shafak S. Aluwini
submission deadline 18 Jun 2026 | 2 articles | Viewed by 2508 | Submission Open
Keywords: stereotactic radiosurgery; clinical outcomes; brachytherapy; IMRT; brain metastases; arteriovenous malformations; functional disorders; radiosurgery
(This special issue belongs to the Section Oncology)
Gynecologic Oncology: Current Therapies and New Frontiers
edited by Laura Paleari and Mariangela Rutigliani
submission deadline 19 Jun 2026 | 1 articles | Viewed by 1034 | Submission Open
Keywords: ovarian cancers; gynecological cancer; drug delivery; AI; screening; new therapies
(This special issue belongs to the Section Obstetrics & Gynecology)
Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition) submission deadline 20 Jun 2026 | 9 articles | Viewed by 35434 | Submission Open
Keywords: obstetrics; gynecology; pathology; pediatric and adolescent gynecology; menopause; urinary disorders; infertility; gynecologic oncology; maternal– fetal medicine; incontinence; menstruation; reproduction; polycystic ovarian syndrome; endometriosis; dysmenorrhea; assisted reproduction; IVF; laparoscopy; hysteroscopy; gynecologic robotic surgery; high-risk pregnancy
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Trauma Care and Emergency Medicine submission deadline 20 Jun 2026 | 5 articles | Viewed by 20902 | Submission Open
Keywords: trauma; trauma care; emergency medicine; pre-hospital; emergency room; intensive care unit
(This special issue belongs to the Section Emergency Medicine)
Clinical Advances in Metabolic Dysfunction-Associated Steatotic Liver Disease
edited by Hirsh D. Trivedi
submission deadline 20 Jun 2026 | 5 articles | Viewed by 14075 | Submission Open
Keywords: metabolic dysfunction-associated steatotic liver disease; MASLD; non-alcoholic fatty liver disease; NAFLD; liver disease; liver fibrosis; metabolic syndrome
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Ultrasound-Guided Biopsy of Gynecologic Tumors: Technique and Clinical Application
edited by and Alexandros Daponte
submission deadline 20 Jun 2026 | 1 articles | Viewed by 11045 | Submission Open
Keywords: ultrasound-guided biopsy; gynecologic tumors; ovarian cancer; biopsy technique; precision diagnosis; endometrial lesions
(This special issue belongs to the Section Obstetrics & Gynecology)
Latest Advances in Orthodontics
edited by
submission deadline 20 Jun 2026 | 5 articles | Viewed by 10811 | Submission Open
Keywords: digital treatment planning; clear aligners; skeletal anchorage; OSAS; artificial intelligence
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Advances in Trauma and Orthopaedic Surgery
edited by Valerio Pace and Pierluigi Antinolfi
submission deadline 20 Jun 2026 | 6 articles | Viewed by 10715 | Submission Open
Keywords: orthopaedic surgery; hand/wrist surgery; tendon injury; ligament injury; artificial intelligence (AI); robotic surgery; orthopaedic injections; nerve injury
(This special issue belongs to the Section Orthopedics)
Evidence-Based Diagnosis and Clinical Management of Low Back Pain submission deadline 20 Jun 2026 | 4 articles | Viewed by 10620 | Submission Open
Keywords: low back pain; classification systems; risk stratification; health services research; management strategies; timing and sequencing; prognosis; predictor; clinical decision making; primary care
(This special issue belongs to the Section Clinical Rehabilitation)
AI in Maternal Fetal Medicine and Perinatal Management
edited by Ariel Many
submission deadline 20 Jun 2026 | 5 articles | Viewed by 10373 | Submission Open
Keywords: maternal fetal medicine; high-risk pregnancy; perinatal management; artificial intelligence (AI) in obstetrics; fetal growth abnormalities; preterm labor prediction
(This special issue belongs to the Section Obstetrics & Gynecology)
Advancements in Gait Rehabilitation: Innovative Approaches and Clinical Insights submission deadline 20 Jun 2026 | 8 articles | Viewed by 10355 | Submission Open
Keywords: sarcopenia; swallowing therapy; physical therapy; early mobilization; early rehabilitation; robot-assisted gait training; neurorehabilitation; wearable sensors
(This special issue belongs to the Section Clinical Rehabilitation)
Therapies for Heart Failure: Clinical Updates and Perspectives
edited by Cristina Tudoran, Stela Iurciuc and Dragos Cozma
submission deadline 20 Jun 2026 | 10 articles | Viewed by 8937 | Submission Open
Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome
(This special issue belongs to the Section Cardiology)
Maternal–Fetal Medicine: Current Status, Challenges, and Future Directions
edited by Jessian Munoz
submission deadline 20 Jun 2026 | 7 articles | Viewed by 8128 | Submission Open
Keywords: maternal– fetal medicine; preterm delivery; preterm birth management; newborn; obstetrics; high-risk pregnancy; perinatal outcome; placenta accreta; fetal surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Clinical Approaches to Breast Cancer Diagnosis and Treatment
edited by
submission deadline 20 Jun 2026 | 6 articles | Viewed by 8015 | Submission Open
Keywords: breast cancer; diagnosis; precision medicine; molecular profiling; targeted therapy; breast-conserving surgery; minimally invasive techniques; artificial intelligence; personalized medicine; radiation therapy
(This special issue belongs to the Section Oncology)
Advances in Diagnosis and Treatment of Urological Cancers submission deadline 20 Jun 2026 | 2 articles | Viewed by 6256 | Submission Open
Keywords: prostate cancer; kidney cancer; urothelial carcinoma; testis cancer; mini-invasive surgery; precision surgery; target therapy; immunotherapy; nuclear medicine; artificial intelligence; augmented reality; biomarkers; prognostic factors and models; focal therapy; radiotherapy; imaging; genetics
(This special issue belongs to the Section Nephrology & Urology)
Advancements in Femtosecond Laser Applications
edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts
submission deadline 20 Jun 2026 | 4 articles | Viewed by 5765 | Submission Open
Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract
(This special issue belongs to the Section Ophthalmology)
Genitourinary Cancers: Clinical Advances and Practice Updates
edited by David Benjamin and Arash Rezazadeh Kalebasty
submission deadline 20 Jun 2026 | 5 articles | Viewed by 5754 | Submission Open
Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology
(This special issue belongs to the Section Nephrology & Urology)
Updates on the Clinical Applications of Dental Restorative Materials
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 5288 | Submission Open
Keywords: restorative dentistry; restorations; adhesive dentistry; resin composites; ceramics; aesthetics; dental materials; direct restorations; indirect restorations; conservative dentistry; prosthetic dentistry; partial restorations; total restorations
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Sepsis: Clinical Advances and Practical Updates
edited by
submission deadline 20 Jun 2026 | 3 articles | Viewed by 5251 | Submission Open
Keywords: sepsis pathophysiology; host immune response; biomarkers for sepsis; early sepsis diagnosis; immunotherapy in sepsis; antimicrobial stewardship
(This special issue belongs to the Section Intensive Care)
Antithrombotic Therapies for Acute Coronary Syndrome and Atrial Fibrillation submission deadline 20 Jun 2026 | 3 articles | Viewed by 5220 | Submission Open
Keywords: atrial fibrillation; acute coronary syndrome; antiplatelet agents; anticoagulants; thrombolysis; direct coagulation factor inhibitors; medical laboratory technology
(This special issue belongs to the Section Cardiology)
Novel Aspects of Endocrine Care: From Patient-Centred Management of Endocrine Diseases to Guidelines Standards submission deadline 20 Jun 2026 | 5 articles | Viewed by 5171 | Submission Open
Keywords: endocrine tumour; hormone; biomarker; neuroendocrine tumour; thyroidectomy; parathyroidectomy; bone; ad-renal gland; osteoporosis; pituitary gland; autoimmune; antibody; clinical study; computed tomography
(This special issue belongs to the Section Endocrinology & Metabolism)
Innovations in Psychosis and Schizophrenia: New Findings and Implications
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 4308 | Submission Open
Keywords: schizophrenia; psychosis; psychopathology; neurobiology; assessment; pharmacological treatment; psychosocial interventions
(This special issue belongs to the Section Mental Health)
New Insights in Maxillofacial Surgery
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 4209 | Submission Open
Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Innovations in the Clinical Management of Retinal Diseases: Emerging Therapies and Visual Rehabilitation submission deadline 20 Jun 2026 | 3 articles | Viewed by 4165 | Submission Open
Keywords: retinal diseases; macular degeneration; maculopathies; diabetic retinopathy; retinal vascular occlusions; retinitis pigmentosa
(This special issue belongs to the Section Ophthalmology)
Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition
edited by and Maciej Dąbrowski
submission deadline 20 Jun 2026 | 4 articles | Viewed by 4124 | Submission Open
Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; transcatheter aortic valve replacement
(This special issue belongs to the Section Cardiovascular Medicine)
Parkinson's Disease: Recent Advances in Diagnosis and Treatment submission deadline 20 Jun 2026 | 3 articles | Viewed by 4043 | Submission Open
Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging
(This special issue belongs to the Section Clinical Neurology)
Autoimmune Diseases and Multisystem Inflammation: Pathophysiology and Therapeutic Strategies
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 3828 | Submission Open
Keywords: autoimmune diseases; cardiovascular diseases; cutaneous diseases; gastrointestinal diseases; pulmonary diseases; renal diseases; systemic manifestation; rheumatoid arthritis; systemic lupus erythematosus; vasculitis
(This special issue belongs to the Section Immunology & Rheumatology)
State of the Art in Cardiac Surgery: Progress, Challenges and Opportunities
edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan
submission deadline 20 Jun 2026 | 3 articles | Viewed by 3680 | Submission Open
Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts
(This special issue belongs to the Section Cardiology)
Risk Factors in Neonatal Intensive Care submission deadline 20 Jun 2026 | 3 articles | Viewed by 3651 | Submission Open
Keywords: neonatal intensive care; infant birth; preterm; neonatal resuscitation; neonatal outcome; growth restriction; prenatal diagnosis; severe maternal pathology and its effects on a newborn; therapeutical hypothermia; parenteral nutrition; neonatal infection; retinopathy of prematurity
(This special issue belongs to the Section Clinical Pediatrics)
Hospital-Acquired Infections: Insights, Prevention, and Control Strategies
edited by
submission deadline 20 Jun 2026 | 4 articles | Viewed by 3307 | Submission Open
Keywords: healthcare-acquired infections; bloodstream infections; hospital‐acquired pneumonia; intestinal infections; clostridium difficile; surgical site infections; urinary tract infections; emergency department
(This special issue belongs to the Section Epidemiology & Public Health)
New Clinical Advances in Breast Reconstruction
edited by
submission deadline 20 Jun 2026 | 4 articles | Viewed by 3179 | Submission Open
Keywords: breast reconstruction; autologous (flap) reconstruction; implant-based reconstruction; microsurgery and perforator flaps; robotic surgery/endoscopic surgery; fat grafting (lipofilling); patient-reported outcomes; reconstructive surgical innovation
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Clinical Advances in Scoliosis and Spinal Disorders: Diagnosis and Management
edited by Tejas Subramanian
submission deadline 20 Jun 2026 | 3 articles | Viewed by 2960 | Submission Open
Keywords: spine surgery; adult spinal deformity; frailty; sarcopenia; muscle health; postoperative recovery; patient-reported outcomes
(This special issue belongs to the Section Orthopedics)
New Perspectives in Maternal–Fetal Medicine
edited by Catalina de Paco-Matallana
submission deadline 20 Jun 2026 | 2 articles | Viewed by 2885 | Submission Open
Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health
(This special issue belongs to the Section Obstetrics & Gynecology)
Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 2847 | Submission Open
Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse
(This special issue belongs to the Section Cardiology)
Innovations in Neurorehabilitation—2nd Edition
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 2735 | Submission Open
Keywords: clinical neurophysiology; neuroengineering; robotics; non-invasive transcranial brain stimulation; spinal stimula-tion; regenerative rehabilitation; neuroimaging; brain– computer interface; brain-spinal interface; virtual reality; higher-level cognitive functions; vision rehabilitation
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in the Pharmacotherapy of Diabetes
edited by Jonathan Watanabe, and
submission deadline 20 Jun 2026 | 1 articles | Viewed by 2715 | Submission Open
Keywords: diabetes; microvascular complications; macrovascular complications; diabetes technology; pharmacoepidemiology; care delivery; novel therapies
(This special issue belongs to the Section Pharmacology)
Current Perspectives and Innovations in Urogynecology
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 2669 | Submission Open
Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Cardiovascular Rehabilitation: The Central Role of Exercise in Prevention and Care
edited by Massimo Pistono
submission deadline 20 Jun 2026 | 3 articles | Viewed by 2546 | Submission Open
Keywords: cardiac rehabilitation; secondary prevention; physical exercise; cardiovascular health; aerobic exercise; cardio-oncology rehabilitation
(This special issue belongs to the Section Cardiovascular Medicine)
Multiple Myeloma: Therapeutic and Management Strategies
edited by Terri Parker
submission deadline 20 Jun 2026 | 2 articles | Viewed by 2044 | Submission Open
Keywords: multiple myeloma; frontline treatment; monoclonal antibodies; sequencing of treatment; immunotherapy; CAR T; Bi-specific T cell engagers; toxicity management
(This special issue belongs to the Section Hematology)
Clinical Insights in Pediatric Dentistry
edited by
submission deadline 20 Jun 2026 | 2 articles | Viewed by 1932 | Submission Open
Keywords: pediatric dentistry; caries management; dental trauma; preventive dentistry; behavior management; interdisciplinary care; clinical innovations
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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