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Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 18 December 2025 | Viewed by 211

Special Issue Editors


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Guest Editor
Department of Cardiac Surgery and Transplantology, Poznan University of Medical Sciences, 61-848 Poznan, Poland
Interests: aortic stenosis; TAVI; heart failure; coronary artery disease; atrial fibrillation
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Guest Editor
Department of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland
Interests: coronary angioplasty; aortic stenosis; transcatheter aortic valve implantation; hypertrophic cardiomyopathy
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Special Issue Information

Dear Colleagues,

It is our pleasure to invite you to contribute to this Special Issue entitled “Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition”. This is a new Special Issue that proceeds from the six papers we published in the first edition. For more details, you can access it here: https://www.mdpi.com/journal/jcm/special_issues/C7511T6741.

Transcatheter aortic valve replacement (TAVI) has evolved rapidly since the first procedure in 2002. Currently, TAVI is the recommended method of treatment for patients with severe aortic stenosis with moderate-to-high surgical risk, in addition to some selected low-risk patients. Diagnostic modalities support the proper qualification for this procedure. Modifications of the technique, bioprostheses, and delivery systems enable operators to perform the procedure relatively safely, even in particularly difficult clinical scenarios. Nevertheless, several troublesome issues may occur during or after the procedure. The aim of this Special Issue is to share experiences in pre-procedural planning, procedural techniques, and post-procedural outcomes in order to broaden the knowledge on TAVI performance and improve TAVI team skills.

We invite authors to share their valuable opinions and the results of their research as original or review papers. We would be very grateful for your outstanding contribution to the further development of TAVI.

Dr. Anna Olasinska-Wisniewska
Dr. Maciej Dąbrowski
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • aortic stenosis
  • transcatheter
  • bioprosthesis
  • TAVI
  • transcatheter aortic valve replacement

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Published Papers (1 paper)

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Review

16 pages, 1803 KB  
Review
Valve-in-Valve Transcatheter Aortic Valve Implantation Versus Redo SAVR for Degenerated Biological Prosthesis: A Narrative Review Stating Our Experience
by Salvatore Torre, Laura Asta, Adriana Sbrigata, Sebastiano Castrovinci, Enrico Amoncelli, Antonio Segreto, Giuseppe Maria Raffa, Gioachino Agostino Giarratana, Vincenzo Argano and Calogera Pisano
J. Clin. Med. 2025, 14(20), 7158; https://doi.org/10.3390/jcm14207158 (registering DOI) - 11 Oct 2025
Abstract
Surgical aortic valve replacement (SAVR) is still the gold-standard treatment for aortic stenosis. However, the increasing use of biological prostheses, even in young patients, makes Valve-in-Valve (ViV) transcatheter aortic valve implantation (TAVI) an attractive option compared to redo SAVR, thanks to its lower [...] Read more.
Surgical aortic valve replacement (SAVR) is still the gold-standard treatment for aortic stenosis. However, the increasing use of biological prostheses, even in young patients, makes Valve-in-Valve (ViV) transcatheter aortic valve implantation (TAVI) an attractive option compared to redo SAVR, thanks to its lower invasiveness and sometimes greater safety. However, there are several technical and anatomical aspects to consider. Therefore, the aim of our review is to examine the main mechanisms responsible for the degeneration of biological prostheses and, subsequently, to analyze the hemodynamic (transvalvular gradients, patient–prosthesis mismatch, paravalvular leakage) and technical (risk of coronary obstruction, prosthetic implantation strategy) aspects that most influence the procedure’s success and long-term outcomes. To this end, we present a case we treated in order to enhance our readers’ experience with this procedure. Currently, ViV TAVI is approved for patients at high surgical risk, but it could become a valid option compared to redo SAVR; however, more clinical trials are needed to better analyze the survival differences between these two procedures. Furthermore, it remains a therapeutic strategy reserved for highly specialized centers due to the technical difficulties involved in its execution. Full article
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