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Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition)
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Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition)

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Obstetrics & Gynecology".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 778

Special Issue Editor

Dr. Panagiotis Christopoulos

E-Mail Website
Guest Editor
2nd Department of Obstetrics and Gynecology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
Interests: gynecology; obstetrics; reproductive; endocrinology; mullerian anomalies; PCOS; pediatric gynecology; high-risk pregnancy; adolescent gynecology; minimally invasive surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Carrying on from the success of the first edition and second edition of the Special Issue “Gynecologic and Obstetric Pathologies: From Birth to Menopause”, this third edition aims to continue publishing a broad range of original, peer-reviewed papers covering the full spectrum of obstetrics and gynecology.

For this Special Issue, we invite submissions on current high-quality research, reporting selected original experimental and clinical investigations in the fields of gynecology, obstetrics, and human reproduction. This Special Issue will address significant topics in gynecology and obstetrics through well-referenced review articles, meta-analyses, practice guidelines, and more. Case reports will also be considered if they have the potential to impact women's healthcare practices.

Topics of interest include general gynecology; reproductive medicine; endocrinology; infertility; pediatric and adolescent gynecology; menopause; urogynecology; gynecologic oncology; oncofertility; pelvic medicine; sexual medicine; minimally invasive gynecologic surgery; and the pros and cons of various techniques in gynecology and obstetrics, as well as high-risk pregnancy, prenatal diagnosis, maternal–fetal medicine, obstetrics, perinatology, and more. This Special Issue will focus particularly on the diagnosis, prediction, prevention, and treatment of obstetrical and gynecological disorders.

Given our global audience, the aim of the second edition of this Special Issue is to play a significant role in educating physicians worldwide. All published content will be accessible to everyone in an open access format.

Dr. Panagiotis Christopoulos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • obstetrics
  • gynecology
  • pathology
  • pediatric and adolescent gynecology
  • menopause
  • urinary disorders
  • infertility
  • gynecologic oncology
  • maternal–fetal medicine
  • incontinence
  • menstruation
  • reproduction
  • polycystic ovarian syndrome
  • endometriosis
  • dysmenorrhea
  • assisted reproduction
  • IVF
  • laparoscopy
  • hysteroscopy
  • gynecologic robotic surgery
  • high-risk pregnancy

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Related Special Issue

Published Papers (2 papers)

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Review

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18 pages, 789 KiB  
Review
Perspective on Perinatal Birth Canal Injuries: An Analysis of Risk Factors, Injury Mechanisms, Treatment Methods, and Patients’ Quality of Life: A Literature Review
by Patrycja Głoćko, Sylwia Janczak, Agnieszka Nowosielska-Ogórek, Wiktoria Patora, Olga Wielgoszewska, Mateusz Kozłowski and Aneta Cymbaluk-Płoska
J. Clin. Med. 2025, 14(10), 3583; https://doi.org/10.3390/jcm14103583 - 20 May 2025
Viewed by 276
Abstract
Perineal injuries are a common complication of vaginal delivery, affecting 75–85% of women. This review examines current knowledge on risk factors, classification, treatment, and quality of life impacts. Risk factors are divided into maternal, foetal, and labour-related categories. Treatment depends on injury severity. [...] Read more.
Perineal injuries are a common complication of vaginal delivery, affecting 75–85% of women. This review examines current knowledge on risk factors, classification, treatment, and quality of life impacts. Risk factors are divided into maternal, foetal, and labour-related categories. Treatment depends on injury severity. First-degree tears can be managed conservatively, with skin glue or suturing—preferably with synthetic absorbable sutures to reduce pain and infection risk. Second-degree tears and episiotomies respond best to continuous non-locking sutures, improving healing, and minimizing postpartum pain. Severe third- and fourth-degree tears require specialised surgical techniques, such as the overlay method for anal sphincter repair, which improves faecal continence. Proper preoperative care, including antibiotics and anaesthesia, enhances outcomes. Episiotomy is controversial; selective use based on clinical indications is recommended over routine practice. Research shows no significant long-term benefits compared to spontaneous tears, and links episiotomy to psychological distress and negative body image. Preventative strategies, like perineal massage and warm compresses during labour, may reduce the risk of severe trauma, particularly in first-time mothers. Perineal trauma can have lasting physical and psychological effects, impacting sexual function, continence, and mental health. Proper diagnosis, treatment, and postpartum care are essential. Future studies should aim to standardise care protocols and explore long-term outcomes to enhance patient quality of life. Full article
(This article belongs to the Special Issue Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition))
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16 pages, 569 KiB  
Systematic Review
Diagnostic Challenges and Management Strategies of Pelvic Inflammatory Disease in Sexually Inactive Pediatric and Adolescent Patients: A Systematic Review of Case Reports
by Adrian Surd, Rodica Mureșan, Andreea Oprea, Kriszta Snakovszki, Lucia Maria Sur, Lia-Oxana Usatiuc, Carmen-Iulia Ciongradi and Ioan Sârbu
J. Clin. Med. 2025, 14(11), 3971; https://doi.org/10.3390/jcm14113971 - 4 Jun 2025
Viewed by 270
Abstract
Background and objectives: Pelvic inflammatory disease (PID), primarily associated with sexually transmitted infections (STIs), represents a diagnostic challenge in virgin pediatric patients due to the often vague, non-specific symptomatology, which can mimic other conditions. Management prioritizes targeted antimicrobial therapy, with surgical intervention reserved [...] Read more.
Background and objectives: Pelvic inflammatory disease (PID), primarily associated with sexually transmitted infections (STIs), represents a diagnostic challenge in virgin pediatric patients due to the often vague, non-specific symptomatology, which can mimic other conditions. Management prioritizes targeted antimicrobial therapy, with surgical intervention reserved for complications like tubo-ovarian abscess (TOA). The present systematic review aimed to critically evaluate the available evidence from case reports of PID in virgin pediatric and adolescent patients. Methods: The search strategy was in accordance with PRISMA guidelines. Case reports published up to March 2025 were searched through PubMed, Embase, Scopus, and Google Scholar databases. We included English-language case reports on non-sexually active pediatric and adolescent patients with available full text, excluding commentaries, reviews, and editorials. The Critical Appraisal Checklist for Case Reports was used for the quality assessment of case reports. Through descriptive analysis, PID symptoms, diagnostic, and management modalities were reviewed. The quality of the included case reports was assessed using the JBI Critical Appraisal Checklist. This review was not registered and did not receive external funding. Results: Among the 56 case reports searched, 20 reports were selected and analyzed based on eight criteria. The most frequently reported symptoms were lower abdominal pain (95.8%), fever (63.6%), and gastrointestinal symptoms (50%). Common comorbidities included urinary tract infections (22.7%), congenital anomalies (18.1%), and appendicitis history (18.1%). Escherichia coli and Streptococcus species were the predominant pathogens identified. All patients received antibiotic therapy, while 90.9% underwent surgical intervention. Favorable outcomes were achieved in 72.7% of cases, though 27.2% experienced complications or recurrences. Conclusions: Although commonly linked to sexual activity, PID should be considered in sexually inactive pediatric patients presenting with abdominal pain and adnexal masses. Early diagnosis, appropriate imaging, and timely treatment are crucial to improve outcomes and reduce complications. The evidence in this review is limited by its reliance on case reports, which may introduce bias and restrict generalizability. Full article
(This article belongs to the Special Issue Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition))
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