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Advances in Trauma Care and Emergency Medicine

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Emergency Medicine".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 3781

Special Issue Editors


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Guest Editor
1. Department of Anesthesiology, Amsterdam University Medical Center, 1081 HV Amsterdam, The Netherlands
2. Helicopter Emergency Medical Service‚ Lifeliner 1, 1044 AN Amsterdam, The Netherlands
Interests: emergency medicine; trauma care; resuscitation; anesthesia; monitoring of circulation; diving medicine; hyper-baric medicine; HEMS
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Anesthesiology, Amsterdam University Medical Center, 1081 HV Amsterdam, The Netherlands
2. Helicopter Emergency Medical Service‚ Lifeliner 1, 1044 AN Amsterdam, The Netherlands
Interests: emergency medicine; trauma; cadiopulmonary resuscitation; anesthesia; medical statistics
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Helicopter Emergency Medical Service‚ Lifeliner 1, 1044 AN Amsterdam, The Netherlands
2. Department of Surgery, Amsterdam University Medical Center, 1105 AZ Amsterdam, The Netherlands
Interests: pre- and in-hospital trauma care; trauma surgery; spine surgery; treatment of open fractures and fracture-related infections; emergency medicine
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The management of trauma and emergency medicine share a broad overlap in their management priorities and respective challenges. Importantly, in both fields, time is of the essence to prevent and limit morbidity and mortality. The initial treatment in both fields focuses on the restoration and stabilization of vital functions, rather than a definitive therapy of the underlying disease. Furthermore, a broad overlap also exists in the organizational approach to both fields: Severe trauma and emergency medical cases are regularly treated before arrival in the hospital already, e.g., by paramedics or prehospital emergency physicians. Also, within the hospital, the initial organizational approach overlaps, with severe trauma cases and emergency medicine cases being presented in the emergency department and usually treated initially by a multidisciplinary team according to international guidelines. After stating those shared aspects to underline why both topics fit and complement each other within one Special Issue, it is also obvious that both fields are highly diverse, and many facets hereof may be presented in this upcoming Special Issue. Thus, it is the aim of this Special Issue to highlight recent advances in trauma care and emergency medicine, including pre-hospital care, the emergency department, the operating room, and the intensive care unit.

The scope of this Special Issue includes, but is not limited to:

  • Organizational aspects of trauma care and emergency medicine;
  • Approaches to life-threatening conditions;
  • Diagnostics, including ultrasonography and monitoring vital functions;
  • Fluid resuscitation and emergency (surgical) procedures;
  • Cardiopulmonary resuscitation;
  • Emergency anesthesia and critical care;
  • Application of novel technologies, e.g., drones or artificial intelligence;
  • Trauma care and emergency care in the austere environment.

We welcome high-quality original studies (clinical and experimental), well-designed meta-analyses, and informative reviews. We look forward to your contribution.

Dr. Lothar Andreas Schwarte
Prof. Dr. Patrick Schober
Dr. Georgios F. Giannakopoulos
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • trauma
  • trauma care
  • emergency medicine
  • pre-hospital
  • emergency room
  • intensive care unit

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Published Papers (2 papers)

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Research

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13 pages, 1382 KiB  
Article
Early Evaluation of Myeloperoxidase and Delta Neutrophil Indices Is Similar to 48 h Sequential Organ Failure Assessment Score for Predicting Multiple Organ Failure After Trauma
by Woo Jin Jung, Hye Sim Kim, Kyoung Chul Cha, Young-Il Roh, Gyo Jin An, Yong Sung Cha, Hyun Kim, Kang Hyun Lee, Sung Oh Hwang and Oh Hyun Kim
J. Clin. Med. 2025, 14(10), 3447; https://doi.org/10.3390/jcm14103447 - 15 May 2025
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Abstract
Background/Objectives: Multiple organ failure is the main cause of mortality in severely injured patients who survive the early post-trauma phase. Myeloperoxidase and delta neutrophil indices may serve useful markers for the early diagnosis of an inflammatory condition. We aimed to ascertain the [...] Read more.
Background/Objectives: Multiple organ failure is the main cause of mortality in severely injured patients who survive the early post-trauma phase. Myeloperoxidase and delta neutrophil indices may serve useful markers for the early diagnosis of an inflammatory condition. We aimed to ascertain the use of these indices for predicting multiple organ failure after a major trauma. Methods: A retrospective study was performed based on a level I trauma center database that included trauma patients with an injury severity score of >15 points. Organ function was evaluated according to the sequential organ failure assessment score within at least 48 h of admission and the myeloperoxidase and delta neutrophil indices, which were measured every morning. Results: A total of 96 patients were included in this study. Compared with the non-multiple-organ-failure group, the multiple organ failure group had similar myeloperoxidase indices but a significantly higher delta neutrophil index. Multivariate logistic regression analysis revealed no significant difference in the predictive power among the post-trauma multiple organ failure models that included various factors, although model 7, which combined the sequential organ failure assessment score and the myeloperoxidase and delta neutrophil indices, tended to have the maximum predictive power. Conclusions: Early delta neutrophil index (DNI) values and the composite model incorporating SOFA, absolute MPXI, and DNI each demonstrated moderate ability to predict multiple organ failure after major trauma. Prospective multicenter studies that include granular treatment variables are warranted to validate these biomarkers and to explore whether their incorporation into real-time decision tools can improve outcomes. Full article
(This article belongs to the Special Issue Advances in Trauma Care and Emergency Medicine)
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Review

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18 pages, 622 KiB  
Review
Extended Focused Assessment with Sonography for Trauma in the Emergency Department: A Comprehensive Review
by Federico M. Bella, Alessandra Bonfichi, Ciro Esposito, Christian Zanza, Abdelouahab Bellou, Domenico Sfondrini, Antonio Voza, Andrea Piccioni, Antonio Di Sabatino and Gabriele Savioli
J. Clin. Med. 2025, 14(10), 3457; https://doi.org/10.3390/jcm14103457 - 15 May 2025
Cited by 1 | Viewed by 3089
Abstract
The Extended Focused Assessment with Sonography for Trauma (eFAST) plays a crucial role in the emergency department (ED) by providing rapid and non-invasive diagnostic information in trauma patients. It is a diagnostic-free fluid detection technique that uses sonography to assess trauma in different [...] Read more.
The Extended Focused Assessment with Sonography for Trauma (eFAST) plays a crucial role in the emergency department (ED) by providing rapid and non-invasive diagnostic information in trauma patients. It is a diagnostic-free fluid detection technique that uses sonography to assess trauma in different anatomical windows of the chest and abdomen and has been accepted in multiple studies as the initial diagnostic tool for torso injuries in blunt abdominal trauma. By promptly identifying potentially life-threatening injuries, such as haemoperitoneum, haemothorax, and cardiac tamponade, eFAST facilitates timely intervention and improves patient outcomes in the ED. The eFAST exam is reliable, with high sensitivity and specificity, even when performed by non-radiological personnel, saving time and resources in the chaotic emergency environment. This review aims to assess the diagnostic reliability and limitations of eFAST in different trauma conditions and to outline its goals in trauma critical care and in “ABCDE” resuscitation. Full article
(This article belongs to the Special Issue Advances in Trauma Care and Emergency Medicine)
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