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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Clinical Treatment for Ocular Vascular Disease and Fundus Disease: Second Edition
edited by , Shohista Saidkasimova and
submission deadline 25 Jul 2025 | 1 articles | Viewed by 834 | Submission Open
Keywords: ocular vascular diseases; fundus disorders; diabetic retinopathy; retinal vein occlusion; age-related macular degeneration; retinal detachment
(This special issue belongs to the Section Ophthalmology)
Minimally Invasive Gynecological Surgery: State of the Art and the Perspectives
edited by Artur Jakimiuk
submission deadline 25 Jul 2025 | 1 articles | Viewed by 745 | Submission Open
Keywords: robotic surgery; laparoscopy; hysteroscopy; gynecological oncolgy surgery; minimally invasive gynecological procedures; reproductive endocrinology; urinary incontinence; endometriosis; advance laparoscopic surgery
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances and Trends in Pediatric Surgery submission deadline 25 Jul 2025 | 1 articles | Viewed by 736 | Submission Open
Keywords: pediatric surgery; minimally invasive surger; robotics; trends; advances
(This special issue belongs to the Section Clinical Pediatrics)
Interventional Cardiology—Challenges and Solutions
edited by
submission deadline 25 Jul 2025 | 1 articles | Viewed by 608 | Submission Open
Keywords: chronic total occlusion; highly calcified coronary or lower extremity arteries; stentless percutaneous coronary intervention; chronic limb threatening ischemia; instent restenosis in the extremity artery diseases; endovascular therapy for pulmonary thromboembolism; transcatheter aortic valve replacemment for the bicuspid aortic valve; transcatheter aortic valve replacement for the valve-in-valve procedure; endovascular therapy for tricospid valve regurgitation; transcatheter edge-to-edge repair for mitral valve regurgitation
(This special issue belongs to the Section Cardiovascular Medicine)
New Perspectives in Chronic Kidney Disease, Transplantation and Immune System
edited by and Dimitrios A. Tsakiris
submission deadline 25 Jul 2025 | 1 articles | Viewed by 560 | Submission Open
Keywords: kidney transplantation; HLA; matching at the epitope level; DSAs; complement; kidney disease epigenetics; diabetic nephropathy; hemostasis; graft rejection; B and T cell immunophenotyping; end stage renal disease
(This special issue belongs to the Section Nephrology & Urology)
Advances in the Field of Cutaneous Malignancies: Background and Clinical Management submission deadline 25 Jul 2025 | Viewed by 402 | Submission Open
Keywords: dermatology; skin cancer; diagnosis; melanoma; basal cell carcinoma; squamous cell carcinoma; imaging; artificial intelligence; dermoscopy; treatment
(This special issue belongs to the Section Dermatology)
Hepatobiliary Surgery: State of the Art and Future Perspectives
edited by and
submission deadline 25 Jul 2025 | 1 articles | Viewed by 398 | Submission Open
Keywords: hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; benign liver lesions
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Genetic Obesity and Health submission deadline 25 Jul 2025 | Viewed by 361 | Submission Open
Keywords: obesity; genetics; health; nutrigenetics; clinical trials; personalized
(This special issue belongs to the Section Endocrinology & Metabolism)
Clinical Updates on Cardiac Electrophysiology
edited by Roberto Rordorf
submission deadline 25 Jul 2025 | Viewed by 194 | Submission Open
Keywords: percutaneous cardiac ablation; surgical cardiac ablation; atrial fibrillation; ventricula tachycardia; non invasive radiotherapy of cardiac arrhythmias; neuromodulation of cardiac arrhythmias
(This special issue belongs to the Section Cardiology)
Innovations in Coronary Artery Disease Treatment and Prevention
edited by
submission deadline 25 Jul 2025 | Viewed by 188 | Submission Open
Keywords: coronary artery disease (CAD); CAD prevention and treatment innovations; CAD biomarkers and imaging; advanced imaging and diagnostics; personalized medicine in cardiology; predictive analytics in CAD
(This special issue belongs to the Section Cardiovascular Medicine)
Robotic-Assisted Colorectal Surgery: Advancements and Clinical Applications submission deadline 25 Jul 2025 | Viewed by 168 | Submission Open
Keywords: rectal cancer; diverticulitis; hemicolectomy; redo surgery; cost-effectiveness
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Hysteroscopic Technology for Gynecological Diseases
edited by Aya Mohr-Sasson and Raanan Meyer
submission deadline 25 Jul 2025 | Viewed by 160 | Submission Open
Keywords: diagnostic hysteroscopy; operative hysteroscopy; uterine sampling; uterine polyp; submucosal fibroid; hysteroscopic dilatation and curettage; hysteroscopic niche repair
(This special issue belongs to the Section Obstetrics & Gynecology)
Gestational Diabetes: Cutting-Edge Research and Clinical Practice
edited by Vendula Bartakova
submission deadline 26 Jul 2025 | 4 articles | Viewed by 3388 | Submission Open
Keywords: gestational diabetes mellitus; oral glucose tolerance test; treatment; pregnancy; peripartal outcomes
(This special issue belongs to the Section Endocrinology & Metabolism)
Research Progress and Challenges in Acute Abdominal Surgery
edited by Matteo Cimino
submission deadline 26 Jul 2025 | 1 articles | Viewed by 1680 | Submission Open
Keywords: acute abdominal emergencies; urgent surgical interventions; minimally invasive techniques; robotic surgery in emergency surgery; open surgery; complications; pain management; postoperative rehabilitation; acute appendicitis; acute biliary disease; intraoperative ultrasonography in emergency surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardiac Surgery: Innovations, Challenges and Opportunities
edited by Kyriakos Spiliopoulos and Keti Vitanova
submission deadline 28 Jul 2025 | Viewed by 428 | Submission Open
Keywords: minimally invasive cardiac surgery; redo cardiac surgery; transcatheter aortic valve implantation (TAVI); advances in mechanical circulatory support; endo-carditis; aortic surgery
(This special issue belongs to the Section Cardiology)
Peritoneal Dialysis—Procedure, Risks, Results submission deadline 28 Jul 2025 | Viewed by 257 | Submission Open
Keywords: peritoneal dialysis; peritoneal catheter placement; peritoneal dialysis outcomes; peritoneal membrane; peritoneal transport; infectious complications; mechanical complications; nutritional status; volume management; peritoneal dialysis solutions
(This special issue belongs to the Section Nephrology & Urology)
Clinical Challenges and Advances in Oncology Radiology
edited by Ammar A Chaudhry
submission deadline 28 Jul 2025 | Viewed by 149 | Submission Open
Keywords: radiomics; theranostics; oncology; targeted therapies; immuno-oncology
(This special issue belongs to the Section Oncology)
Shoulder and Elbow Surgery: Clinical Updates and Perspectives
edited by Taku Hatta, Akihiko Hasegawa and Takuma Yuri
submission deadline 28 Jul 2025 | Viewed by 131 | Submission Open
Keywords: rotator cuff injuries; shoulder arthroplasty; elbow surgery; shoulder surgery; shoulder and elbow disease; arthroscopic surgery; orthopedic surgery
(This special issue belongs to the Section Orthopedics)
Innovations in Neurorehabilitation
edited by
submission deadline 30 Jul 2025 | 7 articles | Viewed by 12897 | Submission Open
Keywords: clinical neurophysiology; neuroengineering; robotics; non-invasive transcranial brain stimulation; spinal stimulation; regenerative rehabilitation; neuroimaging; brain– computer interface; brain– spine interface; virtual reality; environmental control systems; higher level cognitive functions; vision rehabilitation
(This special issue belongs to the Section Clinical Rehabilitation)
Current Trends and Innovations in Arthroscopic Shoulder Surgery
edited by , Sebastian Siebenlist and Lucca Lacheta
submission deadline 30 Jul 2025 | 7 articles | Viewed by 11560 | Submission Open
Keywords: shoulder and adjacent joints; arthroscopic surgery; rotator cuff surgery; reconstructive shoulder surgery; minimally invasive surgery
(This special issue belongs to the Section Orthopedics)
Recent Advances in Acne, Rosacea and Hidradenitis Suppurativa
edited by and Alexandros Stratigos
submission deadline 30 Jul 2025 | 6 articles | Viewed by 9559 | Submission Open
Keywords: acne; rosacea; hidradenitis suppurativa; inflammatory skin diseases; papules; pustules; nodules; cysts; scars; topical medications; oral therapies; biological treatments; surgery; laser and light therapy; challenges; diagnosis; treatment; management; challenges
(This special issue belongs to the Section Dermatology)
Pediatric Pulmonology: Recent Developments and Emerging Trends
edited by Athina L. Papadopoulou
submission deadline 30 Jul 2025 | 4 articles | Viewed by 9357 | Submission Open
Keywords: definition of breath sounds; lung– gut axis pathophysiology; disease endotypes and phenotypes; asthma management in children; bronchiolitis spectrum; pediatric bronchopulmonary dysplasia; pulmonary function testing in pediatric patients; pediatric sleep-disordered breathing; neonatal respiratory distress syndrome; childhood interstitial lung diseases; pulmonary hypertension in children; biomarkers in pediatric lung diseases; allergy and the lungs; diagnostic and therapeutic challenges in bronchoscopy; gene therapy in cystic fibrosis
(This special issue belongs to the Section Clinical Pediatrics)
Sepsis: New Insights into Diagnosis and Treatment
edited by and Etrusca Brogi
submission deadline 30 Jul 2025 | 6 articles | Viewed by 8481 | Submission Open
Keywords: sepsis and sepsis subphenotypes; adjuvant therapy; blood purification strategies; immunomonitoring and immunotherapy; the microbiome in sepsis; crosstalk in multi-organ failure (MOF); ultrasound in sepsis (POCUS); sepsis-induced coagulophaty and DIC; antibiotic therapy; multimodal approaches to surgical source control
(This special issue belongs to the Section Infectious Diseases)
Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Recent Advances and Perspectives
edited by Ehud I. Assia
submission deadline 30 Jul 2025 | 8 articles | Viewed by 5422 | Submission Open
Keywords: premium IOLs (multifocal and toric); IOL power calculation; biometry and imaging; complications and management; laser vision correction; phakic IOLs; femtosecond-laser-assisted cataract surgery; AI (artificial intelligence) and cataract/refractive surgery; accommodative lenses
(This special issue belongs to the Section Ophthalmology)
Adult Congenital Heart Disease: Latest Advances and Prospects submission deadline 30 Jul 2025 | 3 articles | Viewed by 5375 | Submission Open
Keywords: adult congenital heart disease; heart failure; Fontan circulation; Tetralogy of Fallot; cathetherisation and structural interventions
(This special issue belongs to the Section Cardiology)
New Insights into Joint Arthroplasty
edited by
submission deadline 30 Jul 2025 | 8 articles | Viewed by 5338 | Submission Open
Keywords: total hip arthroplasty; total knee arthroplasty; robotic-assisted technology and navigation; modern implant materials; modern implant fixation techniques; alignment in TKA; spinopelvic alignment in THA
(This special issue belongs to the Section Orthopedics)
Transcatheter Aortic Valve Implantation and Replacement: Prospects and Challenges
edited by Konstantinos Toutouzas and
submission deadline 30 Jul 2025 | 3 articles | Viewed by 3340 | Submission Open
Keywords: TAVI; aortic stenosis; valve-in-valve; structural heart disease; TAVI-in-TAVI
(This special issue belongs to the Section Cardiology)
Oral Health in Children: Clinical Management submission deadline 30 Jul 2025 | 3 articles | Viewed by 2937 | Submission Open
Keywords: pediatric oral health; early childhood caries; preventive strategies; comprehensive clinical approach; early detection; oral care; minimal intervention dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Advancing Psycho-Oncology: Multidimensional Approaches and Challenges to Cancer Care submission deadline 30 Jul 2025 | 2 articles | Viewed by 2703 | Submission Open
Keywords: psycho-oncology; cancer care; adaptation process; illness experience; risk and protective factors; mental health care; oncofertility; palliative care; critical experience; prevention; qualitative and quantitative methods; quality of life; health behaviors
(This special issue belongs to the Section Mental Health)
Recent Advances in Rehabilitation of Patients with Multiple Sclerosis (MS)
edited by
submission deadline 30 Jul 2025 | 3 articles | Viewed by 2607 | Submission Open
Keywords: multiple sclerosis; rehabilitation; virtual reality; telerehabilitation; quality of life
(This special issue belongs to the Section Clinical Neurology)
Clinical New Insights into Management of Scoliosis
edited by Piotr Janusz and Marcin Tyrakowski
submission deadline 30 Jul 2025 | 3 articles | Viewed by 2598 | Submission Open
Keywords: scoliosis; idiopathic scoliosis; congenital scoliosis; neuromuscular scoliosis; degenerative scoliosis; kyphosis; spine deformation; scoliosis etiology; surgical treatment; non-surgical treatment
(This special issue belongs to the Section Orthopedics)
Clinical Application of Radiotherapy in Modern Oncology submission deadline 30 Jul 2025 | 2 articles | Viewed by 1812 | Submission Open
Keywords: brain metastasis; bone metastasis; brain tumors; head and neck cancers; thoracic oncology; breast cancer; prostate cancer; sarcoma
(This special issue belongs to the Section Oncology)
Plastic Surgery: Challenges and Future Directions
edited by Philip Brazio and Edward C. Ray
submission deadline 30 Jul 2025 | 1 articles | Viewed by 1740 | Submission Open
Keywords: plastic surgery; reconstructive surgery; esthetic surgery; innovation; challenges; technology
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
New Insights into Peritoneal Dialysis and Hemodialysis: 2nd Edition submission deadline 30 Jul 2025 | 1 articles | Viewed by 1084 | Submission Open
Keywords: hemodialysis; peritoneal dialysis; end-stage renal disease; kidney replacement therapy (KRT); pathophysiology; di-alysis membranes; dialysis preparation; dialysis modality; cardiovascular events; vascular access; PD-related perito-nitis; unfavorable adverse effects; complications; challenges; inflammation
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances of Glaucoma: Current Status and Prospects
edited by Rubén Sánchez-Jean, and Federico Sáenz-Francés San Baldomero
submission deadline 30 Jul 2025 | 1 articles | Viewed by 878 | Submission Open
Keywords: glaucoma surgery; new techniques; minimally invasive glaucoma surgery; intraocular pressure; optometry; IOLs designs
(This special issue belongs to the Section Ophthalmology)
Current Challenges and Advancements in Lateral Skull Base Surgery
edited by Alessia Rubini
submission deadline 30 Jul 2025 | 1 articles | Viewed by 829 | Submission Open
Keywords: lateral skull base; neurotology; jugular foramen; cerebellopontine angle; petrous apex; inner ear; acoustic neuroma; jugular paraganglioma; transtemporal approaches; infratemporal approaches
(This special issue belongs to the Section Otolaryngology)
Metabolic Dysregulation Across the Spectrum from Anorexia Nervosa to Obesity
edited by Andriana C. Kaliora
submission deadline 30 Jul 2025 | Viewed by 202 | Submission Open
Keywords: metabolic dysregulation; anorexia nervosa; obesity; environmental factors in metabolic health; gut microbiota and metabolism; hormonal regulation of appetite; inflammation and metabolic disorders; dietary influence on metabolism
(This special issue belongs to the Section Endocrinology & Metabolism)
Advances in the Treatment of Glaucoma and Ocular Hypertension
edited by Ahnul Ha
submission deadline 30 Jul 2025 | Viewed by 165 | Submission Open
Keywords: glaucoma; ocular hypertension; intraocular pressure (IOP); minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI); neuroprotection; meta-analysis
(This special issue belongs to the Section Ophthalmology)
Clinical Updates in Bleeding and Thrombotic Disorders
edited by
submission deadline 30 Jul 2025 | Viewed by 124 | Submission Open
Keywords: autoimmune-acquired coagulation deficiency; acquired hemophilia A; disseminated intravascular coagulation; thrombotic microangiopathy; venous thromboembolism; acute coronary syndrome; clot waveform analysis; thrombin generation test; thromboelastogram
(This special issue belongs to the Section Hematology)
The Current Trend in the Management of Bruxism and Temporomandibular Disorders submission deadline 31 Jul 2025 | 5 articles | Viewed by 19480 | Submission Open
Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss
edited by David Saceda-Corralo
submission deadline 31 Jul 2025 | 5 articles | Viewed by 18784 | Submission Open
Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss
(This special issue belongs to the Section Dermatology)
Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment
edited by
submission deadline 31 Jul 2025 | 9 articles | Viewed by 16955 | Submission Open
Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety
(This special issue belongs to the Section Immunology)
New Clinical Advances in Psoriasis and Psoriatic Arthritis
edited by and Alessandra Narcisi
submission deadline 31 Jul 2025 | 6 articles | Viewed by 14398 | Submission Open
Keywords: psoriasis; psoriatic arthritis; inflammatory skin disease; inflammatory autoimmune disease; immunotherapy; autoimmunity; comorbidities; therapeutic; diagnosis; treatment; management; biologics
(This special issue belongs to the Section Dermatology)
Acute Respiratory Failure: Innovations and Clinical Insights
edited by
submission deadline 31 Jul 2025 | 3 articles | Viewed by 10791 | Submission Open
Keywords: ARF; mechanical ventilation; VILI; PSILI; NIV; HFNO; weaning; EIT; lung US
(This special issue belongs to the Section Intensive Care)
Clinical Advances and Challenges in Vascular and Endovascular Medicine
edited by Luca Bertoglio
submission deadline 31 Jul 2025 | 7 articles | Viewed by 10000 | Submission Open
Keywords: vascular and endovascular medicine; minimally invasive cardiovascular surgery; vascular diseases; endovascular technologies; endovascular surgery; aortic dissection
(This special issue belongs to the Section Vascular Medicine)
Vascular Surgery: Current Status and Future Perspectives
edited by Murray L. Shames and Adam Tanious
submission deadline 31 Jul 2025 | 4 articles | Viewed by 9781 | Submission Open
Keywords: vascular history; peripheral arterial disease; aortic aneurysm; aortic dissection; carotid disease
(This special issue belongs to the Section Vascular Medicine)
Clinical Advances in Endoscopic Ultrasound-Guided Diagnosis and Treatment
edited by Nicola Muscatiello
submission deadline 31 Jul 2025 | 5 articles | Viewed by 9110 | Submission Open
Keywords: endoscopic ultrasound (EUS); pancreas; cancer; lumen apposing metal stent (LAMS); stent
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Orthopedic Surgery: Latest Advances and Future Prospects
edited by Andrea Marinozzi and
submission deadline 31 Jul 2025 | 6 articles | Viewed by 8886 | Submission Open
Keywords: custom-made; regenerative; prosthetic; noninvasive surgery; robotic surgery; percutaneous surgery; minimally invasive surgery
(This special issue belongs to the Section Orthopedics)
Oral and Maxillofacial Surgery: Current Updates and Perspectives submission deadline 31 Jul 2025 | 5 articles | Viewed by 8241 | Submission Open
Keywords: current updates in oral and maxillofacial surgery; new insights in oral medicine; advances in dental implantology; 3D pre-surgical evaluation in oral and maxillofacial surgery; regenerative dentistry
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Endoscopic Techniques in Digestive and Gynecological Diseases
edited by , Teresa Mascarenhas and
submission deadline 31 Jul 2025 | 3 articles | Viewed by 7983 | Submission Open
Keywords: endoscopy; gastroenterology; gynecology; colonoscopy; colposcopy; artificial intelligence; capsule endoscopy; upper endoscopy; hysteroscopy; pancreatobiliary endoscopy
(This special issue belongs to the Section General Surgery)
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