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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Interventional Cardiology: Clinical Advances and Future Perspectives
edited by Antonio Landi and
submission deadline 20 May 2026 | 1 articles | Viewed by 655 | Submission Open
Keywords: percutaneous coronary intervention; myocardial infarction; interventional cardiology; cardiac catheterization; coronary artery disease; antithrombotic therapy; intravascular imaging; acute coronary syndrome; chronic coronary syndrome
(This special issue belongs to the Section Cardiology)
Audiology and Phoniatrics in Head and Neck Surgery: Functional Assessment, Rehabilitation Strategies, and Quality of Life Outcomes
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 646 | Submission Open
Keywords: audiology; phoniatrics; voice disorders; hearing preservation; speech rehabilitation; head and neck surgery; functional outcomes; quality of life; voice analysis; audiometry; cochlear implants; dysphagia; laryngeal surgery
(This special issue belongs to the Section Otolaryngology)
Clinical Research in Vascular Access Devices
edited by
submission deadline 20 May 2026 | 1 articles | Viewed by 441 | Submission Open
Keywords: short peripheral catheters; long peripheral catheters; midline; peripherally inserted central catheters (PICCs); femoral-inserted central catheters (FICCs); centrally inserted central catheters (CICCs); totally implantable venous access devices (TIVAD); catheter-related bloodstream infection (CRBSI); catheter-associated bloodstream infection (CABSI); central line-associated bloodstream infection (CLABSI); catheter-related thrombosis (CRT); fibroblastic sleeve; infiltration; extravasation
(This special issue belongs to the Section Vascular Medicine)
Novel Approaches in Cataract and Refractive Surgery
edited by Stephen T. Armenti
submission deadline 20 May 2026 | Viewed by 350 | Submission Open
Keywords: cataract surgery; complex cataract surgery; secondary intraocular lens surgery; refractive surgery (LASIK; PRK; SMILE); astigmatism correction; multifocal intraocular lenses; femtosecond laser; dropless cataract surgery
(This special issue belongs to the Section Ophthalmology)
Key Quality Indicators in Diagnosis and Treatment of Respiratory Diseases
edited by
submission deadline 20 May 2026 | Viewed by 347 | Submission Open
Keywords: key quality indicators; respiratory disorders; audit; quality improvement; real-life data
(This special issue belongs to the Section Respiratory Medicine)
Ventricular Assist Devices: Clinical Advances in Practice and Future Perspectives
edited by Balakrishnan M. Mahesh
submission deadline 20 May 2026 | Viewed by 328 | Submission Open
Keywords: ventricular assist device; mechanical circulatory support; pulsatile pneumatic devices; microaxial intraventricular de-vices; magnetically levitated devices; cardiac transplantation; donor circulatory death; normothermic regional perfusion
(This special issue belongs to the Section Cardiology)
Diagnosis, Monitoring, and Treatment of Myocardial Infarction: 2nd Edition
edited by
submission deadline 20 May 2026 | Viewed by 304 | Submission Open
Keywords: myocardial infarction; diagnosis; monitoring; treatment; acute MI
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Diagnosis and Management of Scoliosis
edited by
submission deadline 20 May 2026 | Viewed by 301 | Submission Open
Keywords: scoliosis; spinal deformities; therapeutic strategies; personalized care; quality of life
(This special issue belongs to the Section Orthopedics)
Contemporary Advances in Joint Arthroplasty: Optimizing Outcomes and Expanding Indications submission deadline 20 May 2026 | Viewed by 296 | Submission Open
Keywords: joint arthroplasty; total joint replacement; revision arthroplasty; robotic-assisted surgery; periprosthetic joint infection (PJI); enhanced recovery after surgery (ERAS); machine learning; artifical intelligence
(This special issue belongs to the Section Orthopedics)
Surgery in the Era of Neoadjuvant Immune Checkpoint Inhibitors Therapy for Thoracic Oncology
edited by
submission deadline 20 May 2026 | Viewed by 282 | Submission Open
Keywords: neoadjuvant therapy; immune checkpoint inhibitors; unresectable disease; lung cancer; locally advanced lung cancer
(This special issue belongs to the Section General Surgery)
Clinical Research Progress in Atrial Fibrillation
edited by
submission deadline 20 May 2026 | Viewed by 280 | Submission Open
Keywords: atrial fibrillation; atrial arrhythmias; cardiac fibrosis; inflammation; electrical remodeling
(This special issue belongs to the Section Cardiology)
Prevention, Treatment, and Prognosis of Cerebral Aneurysms
edited by
submission deadline 20 May 2026 | Viewed by 268 | Submission Open
Keywords: cerebral aneurysm; subarachnoid hemorrhage; clipping; interventional surgery; mortarity; long-term; surgical com-plication; bypass
(This special issue belongs to the Section Clinical Neurology)
Clinical Advances in Hemodialysis: 2nd Edition
edited by Maurizio Bossola
submission deadline 20 May 2026 | Viewed by 252 | Submission Open
Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy
(This special issue belongs to the Section Nephrology & Urology)
Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies
edited by Carla Contaldi
submission deadline 20 May 2026 | Viewed by 244 | Submission Open
Keywords: cardiomyopathies; heart failure; genetic mutations; molecular mechanisms; advanced cardiac imaging; cardiac MRI; precision medicine; risk stratification
(This special issue belongs to the Section Cardiology)
Clinical Challenges in Pancreatitis Management
edited by
submission deadline 20 May 2026 | Viewed by 231 | Submission Open
Keywords: acute pancreatitis; chronic pancreatitis; medical management; surgical management; nutritional support; pancreatic diabetes; clinical research; reviews
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Strategies in Complex Hand Trauma: Bridging Orthopedics, Plastic Surgery and Rehabilitation
edited by Clarisa Simón-Pérez and
submission deadline 20 May 2026 | Viewed by 221 | Submission Open
Keywords: complex hand trauma; orthopedics; plastic surgery; microsurgery; rehabilitation; functional reconstruction; multidis-ciplinary management
(This special issue belongs to the Section General Surgery)
Clinical Advances in Venous Thrombosis
edited by Nicola Mumoli
submission deadline 20 May 2026 | Viewed by 188 | Submission Open
Keywords: direct oral anticoagulants (DOACs); cancer-associated thrombosis (CAT); venous thromboembolism (VTE); thrombolytic therapy; post-thrombotic syndrome (PTS); artificial intelligence in VTE prediction
(This special issue belongs to the Section Vascular Medicine)
Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease
edited by Josuel Ora
submission deadline 20 May 2026 | 1 articles | Viewed by 185 | Submission Open
Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities
(This special issue belongs to the Section Respiratory Medicine)
Valvular Heart Disease: Current Knowledge and Therapeutic Prospects
edited by Simona Mega
submission deadline 20 May 2026 | Viewed by 183 | Submission Open
Keywords: valvular heart disease; echocardiographic assessment; cardiovascular imaging; valvular regurgitation; valvular stenosis; structural heart intervention; minimally invasive cardiac surgery; catheter-based interventions
(This special issue belongs to the Section Cardiology)
The Application of Mechanical Circulatory Support Within Cardiology Practice
edited by
submission deadline 20 May 2026 | Viewed by 171 | Submission Open
Keywords: mechanical circulatory support (MCS); cardiogenic shock; intra-aortic balloon pumping (IABP); extracorporeal membranous oxygenation (ECMO); Impella; ventricular assist device (VAD)
(This special issue belongs to the Section Cardiology)
Clinical Challenges in Uterus Transplant Management
edited by Giuliano Testa
submission deadline 20 May 2026 | Viewed by 158 | Submission Open
Keywords: uterus transplant; absolute uterine infertility; fertility treatment; immunosuppression in uterus transplant; pregnancy complications; uterine donor evaluation
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Features and Management of Psychosis
edited by , and Michael Hadjulis
submission deadline 22 May 2026 | 5 articles | Viewed by 19473 | Submission Open
Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis
(This special issue belongs to the Section Mental Health)
Multiparametric Ultrasound Techniques for Liver Disease Assessments
edited by Francesco Giangregorio
submission deadline 22 May 2026 | 2 articles | Viewed by 6221 | Submission Open
Keywords: ultrasound; multiparametric ultrasound; hepatic ultrasound; contrast-enhanced ultrasound; contrast agents; diffuse hepatic diseases; focal liver lesions; hepatic elastography; liver stiffness; hepatic endosonography; hepatic EUS
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Clinical Updates on Rheumatoid Arthritis: 2nd Edition
edited by Francesca Bandinelli
submission deadline 22 May 2026 | 5 articles | Viewed by 4968 | Submission Open
Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease
(This special issue belongs to the Section Immunology & Rheumatology)
Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management submission deadline 22 May 2026 | 1 articles | Viewed by 4968 | Submission Open
Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management
(This special issue belongs to the Section Cardiology)
Thoracic Surgery: Recent Developments and Future Challenges
edited by and Lucio Cagini
submission deadline 22 May 2026 | 1 articles | Viewed by 3352 | Submission Open
Keywords: VATS; RATS; ERAS; sublobar resection; minimally invasive thoracic surgery; target therapy; nodule localization
(This special issue belongs to the Section Respiratory Medicine)
Thrombotic Risk and Its Management Across Diverse Clinical Settings
edited by Samuel Bogdan Todor and Ana Maria Vlǎdǎreanu
submission deadline 22 May 2026 | 2 articles | Viewed by 2921 | Submission Open
Keywords: thrombosis; thrombotic risk; hematologic disorders; thrombophilia; myeloproliferative neoplasms; antithrombotic therapy; cardiovascular diseases; biomarkers
(This special issue belongs to the Section Hematology)
Role of Platelet in Inflammation, Infection, and Immune Response submission deadline 22 May 2026 | Viewed by 733 | Submission Open
Keywords: platelets; platelet count; dual antiplatelet therapy; inflammation; thrombosis; inflammation; hemostasis; immune response
(This special issue belongs to the Section Hematology)
Clinical Pharmacology: Adverse Drug Reactions
edited by and Ivana Mudnić
submission deadline 25 May 2026 | 11 articles | Viewed by 61714 | Submission Open
Keywords: pharmacology; adverse drug reactions; drug interactions; pharmacovigilance; drug safety
(This special issue belongs to the Section Pharmacology)
Neurovascular Diseases: Clinical Advances and Challenges
edited by , Silky Chotai, Alessandro Di Rienzo and Joham Choque-Velasquez
submission deadline 25 May 2026 | 13 articles | Viewed by 43681 | Submission Open
Keywords: neurovascular diseases; ischemic stroke; hemorrhagic stroke; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms
(This special issue belongs to the Section Clinical Neurology)
The Association Between Sleep Disorders and Metabolic and Mental Health submission deadline 25 May 2026 | 9 articles | Viewed by 25989 | Submission Open
Keywords: sleep medicine; sleep apnea; hypoxia; metabolism; mental health; women’ s health
(This special issue belongs to the Section Mental Health)
Ventilation in Critical Care Medicine: 2nd Edition
edited by Gianluca Zani
submission deadline 25 May 2026 | 3 articles | Viewed by 25409 | Submission Open
Keywords: invasive ventilation; non-invasive ventilation; acute respiratory failure; best PEEP; respiratory weaning; respiratory mechanics; ventilation and perfusion; personalized ventilation
(This special issue belongs to the Section Intensive Care)
Maxillo-Facial Surgery: New Insights and Technologies in Head and Neck
edited by Federica Ruggiero
submission deadline 25 May 2026 | 7 articles | Viewed by 16804 | Submission Open
Keywords: oral and maxilla-facial surgery; orthognathic surgery; cranio-facial surgery; head and neck surgery; augmented reality; navigation; finite element modeling; virtual surgical planning; patient-specific implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Recent Progress in Rehabilitation Medicine—3rd Edition
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 14359 | Submission Open
Keywords: neuro-rehabilitation; cognitive rehabilitation; spinal rehabilitation; orthopedic rehabilitation; pediatric rehabilitation; cancer rehabilitation; visceral rehabilitation; cardiac rehabilitation; pulmonary rehabilitation; renal rehabilitation; hepatic rehabilitation; rehabilitation for transplantation; fitness; peak VO2; multimorbidity and multiple disabilities (MMD); adding life to years and years to life
(This special issue belongs to the Section Clinical Rehabilitation)
Preventive, Diagnostic and Therapeutic Strategies for Abdominal Surgery Complications (Second Edition)
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 13264 | Submission Open
Keywords: complications; diagnosis; treatment; management; morbidity; abdomen; abdominal surgery; outcome; postoperative
(This special issue belongs to the Section General Surgery)
Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition submission deadline 25 May 2026 | 8 articles | Viewed by 12903 | Submission Open
Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract
(This special issue belongs to the Section Ophthalmology)
Oral and Maxillofacial Surgery: Diagnosis, Management and Future Opportunities
edited by
submission deadline 25 May 2026 | 6 articles | Viewed by 11722 | Submission Open
Keywords: head and neck oncology; free flaps; oral surgery; malformative surgery; traumatology; endoscopy; preprosthetic surgery; reconstructive surgery; vascular malformations; osteonecrosis
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Diagnosis and Management of Vestibular Disorders
edited by , Mario Habek and
submission deadline 25 May 2026 | 9 articles | Viewed by 11643 | Submission Open
Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management
(This special issue belongs to the Section Otolaryngology)
Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition
edited by Nikos Nikolettos and
submission deadline 25 May 2026 | 4 articles | Viewed by 9708 | Submission Open
Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Future Opportunities in Thoracic Surgery: The Cutting Edge: 2nd Edition
edited by
submission deadline 25 May 2026 | 2 articles | Viewed by 7893 | Submission Open
Keywords: surgical resection; immunotherapy; target therapy; thoracic surgery; thoracic oncology; lung cancer
(This special issue belongs to the Section Respiratory Medicine)
Advances in Maxillofacial Surgery—Historical and Future Perspectives and Controversies submission deadline 25 May 2026 | 6 articles | Viewed by 6995 | Submission Open
Keywords: oral oncology; facial skeleton; oral cavity; surgical approaches; head and neck; parotid tumors; jaw cysts and tumors; bone healing; patient-specific solutions; surgery planning; artificial intelligence; soft tissues; cancers and tumors of the oral cavity; microsurgery perspectives; open surgery; endoscopic surgery; trauma surgery; facial traumatology; bone and soft tissues healing after trauma; jaw deformities; orthognathic surgery today and tomorrow
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Autoimmune-Induced Alopecia and Emerging Therapies in Hair Loss—2nd Edition
edited by David Saceda-Corralo
submission deadline 25 May 2026 | 2 articles | Viewed by 6166 | Submission Open
Keywords: autoimmune-induced alopecia; alopecia areata; cicatricial alopecia; occurs; hair loss; frontal fibrosing alopecia
(This special issue belongs to the Section Dermatology)
Novel Insights into the Diagnosis and Management of Inflammatory Bowel Disease (IBD)
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 6086 | Submission Open
Keywords: inflammatory bowel disease; non-invasive biomarkers; abdominal ultrasonography; colonoscopy; biologic therapy; small molecules; mucosal healing; brain-gut axis; dysbiosis; colorectal dysplasia
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
The Rebirth of Ventral Skull Base Surgery through Multiportal Approaches: Endonasal, Transorbital, Transmaxillary and Transoral Routes
edited by Matteo de Notaris and Francesco Corrivetti
submission deadline 25 May 2026 | 4 articles | Viewed by 5490 | Submission Open
Keywords: skull base surgery; neuroendoscopy; neuroanatomy; multiportal approaches; technical advancements
(This special issue belongs to the Section Clinical Neurology)
Non-Small Cell Lung Cancer (NSCLC): Recent Advances in Clinical Diagnosis and Treatment
edited by
submission deadline 25 May 2026 | 7 articles | Viewed by 4957 | Submission Open
Keywords: novel screening tool; cancer biomarkers; predictive marker of immunotherapy; targeted therapy; radiotherapy; non-small cell lung cancer
(This special issue belongs to the Section Oncology)
Advances in Ablation Therapy for Atrial Fibrillation: Innovations and Clinical Applications
edited by Ioanna Koniari
submission deadline 25 May 2026 | 4 articles | Viewed by 4750 | Submission Open
Keywords: atrial fibrillation; ablation; PFA; PVI; non-thermal energy; mapping system
(This special issue belongs to the Section Cardiology)
Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition
edited by Alessia Mattei, Rita Cataldo and
submission deadline 25 May 2026 | 4 articles | Viewed by 4043 | Submission Open
Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit
(This special issue belongs to the Section Anesthesiology)
Clinical Advances of Breast Surgery and Reconstruction submission deadline 25 May 2026 | 3 articles | Viewed by 3967 | Submission Open
Keywords: breast reconstruction; autologous breast reconstruction; implant-based breast reconstruction; DIEP; LICAP; breast implant infection
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Advanced Hepato-Pancreato-Biliary Surgery: Clinical Innovations and Improved Outcomes
edited by Ahmad Mahamid and Riad Haddad
submission deadline 25 May 2026 | 3 articles | Viewed by 3650 | Submission Open
Keywords: liver surgery; pancreas surgery; biliary surgery; robotic HPB surgery; single incision surgery; prognostic biomarkers; perioperative clinical care; postoperative complications
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Modern Blood Banking and Transfusion in Clinical Practice: Second Edition
edited by
submission deadline 25 May 2026 | 3 articles | Viewed by 3592 | Submission Open
Keywords: blood transfusion therapy; patient blood management; restrictive transfusion; cell therapy; platelet transfusion
(This special issue belongs to the Section Hematology)
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