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Advances in Diagnosis and Treatment of Urological Cancers
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Advances in Diagnosis and Treatment of Urological Cancers

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 406

Special Issue Editors

Dr. Davide Campobasso

E-Mail Website
Guest Editor
Urology Unit, University Hospital of Parma, Parma, Italy
Interests: laparoscopic urology; endourology; urologic oncology; urolithiasis; robotics and minimally invasive urology; urologic surgical procedures; kidney cancer; bladder cancer; prostate cancer; artificial intelligence
Dr. Stefano Puliatti

E-Mail Website
Guest Editor
Urology Department of the University Hospital (AOU), Modena, Italy
Interests: laparoscopic urology; endourology; urologic oncology; urolithiasis; robotics and minimally invasive urology; urologic surgical procedures; kidney cancer; bladder cancer; prostate cancer; artificial intelligence
Special Issues, Collections and Topics in MDPI journals
Dr. Daniele Amparore

E-Mail Website
Guest Editor
Department of Urology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, 10043 Turin, Italy
Interests: laparoscopic urology; endourology; urologic oncology; urolithiasis; robotics and minimally invasive urology; urologic surgical procedures; kidney cancer; bladder cancer; prostate cancer; artificial intelligence; augmented reality
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to inform you that we are organizing a new Special Issue entitled “Advances in Diagnosis and Treatment of Urological Cancers” for the Journal of Clinical Medicine.

The management of urological cancers has significantly changed in recent years with the introduction of new imaging modalities and medical treatments. The advent of new minimally invasive approaches and the application of artificial intelligence have opened new horizons.

The purpose of this Special Issue is to summarize the latest innovations in the diagnostic and therapeutic management of urological cancers and the future perspectives that may derive from current research.

Radiologists, radiation oncologists, oncologists, and urologists are encouraged to submit their findings as original articles or reviews to this Special Issue.

Dr. Davide Campobasso
Dr. Stefano Puliatti
Dr. Daniele Amparore
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • prostate cancer
  • kidney cancer
  • urothelial carcinoma
  • testis cancer
  • mini-invasive surgery
  • precision surgery
  • target therapy
  • immunotherapy
  • nuclear medicine
  • artificial intelligence
  • augmented reality
  • biomarkers
  • prognostic factors and models
  • focal therapy
  • radiotherapy
  • imaging
  • genetics

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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Research

11 pages, 383 KiB  
Article
Perioperative Complications and In-Hospital Mortality After Radical Prostatectomy in Prostate Cancer Patients with a History of Heart Valve Replacement
by Natali Rodriguez Peñaranda, Carolin Siech, Letizia Maria Ippolita Jannello, Francesco Di Bello, Mario de Angelis, Jordan A. Goyal, Fred Saad, Shahrokh F. Shariat, Nicola Longo, Alberto Briganti, Ottavio de Cobelli, Felix K. H. Chun, Stefano Di Bari, Ivan Matteo Tavolini, Stefano Puliatti, Salvatore Micali and Pierre I. Karakiewicz
J. Clin. Med. 2025, 14(14), 5035; https://doi.org/10.3390/jcm14145035 - 16 Jul 2025
Viewed by 176
Abstract
Objective: To test for in-hospital mortality and complication rates in a population-based group of patients with vs. without a history of heart valve replacement undergoing radical prostatectomy (RP). Methods: Relying on the National Inpatient Sample (2000–2019), prostate cancer patients undergoing RP were stratified [...] Read more.
Objective: To test for in-hospital mortality and complication rates in a population-based group of patients with vs. without a history of heart valve replacement undergoing radical prostatectomy (RP). Methods: Relying on the National Inpatient Sample (2000–2019), prostate cancer patients undergoing RP were stratified according to the presence or absence of heart-valve replacement. Multivariable logistics and Poisson regression models addressed adverse hospital outcomes. Results: Within the NIS, 220,358 patients underwent RP. Of those, 694 (0.3%) had a history of heart valve replacement. The patients undergoing heart valve replacement were older (median age 66 vs. 62 years). The proportion of patients with a history of heart valve replacement increases with the Charlson Comorbidity Index (CCI): CCI 0–0.3%, CCI 1–0.4%, and CCI ≥ 2–0.7%. Patients with a history of heart valve replacement exhibited higher rates of postoperative bleeding (<1.5% vs. <0.1%; odds ratio (OR) 16.2; p < 0.001), cardiac complications (7.5% vs. 1.2%; OR 3.9; p < 0.001), infections (<1.5% vs. 0.1%; OR 3.7; p = 0.01), critical care therapy (CCT) use (<1.5% vs. 0.4%; OR 2.5; p = 0.003), intraoperative complications (8.8% vs. 4.1%; OR 1.9; p < 0.001), transfusions (11% vs. 7.2%; OR 1.5; p < 0.001), longer hospital stay (mean 3.39 vs. 2.37 days; rates ratio [RR] 1.4; p < 0.001), and higher estimated hospital cost (median 33,539 vs. 30,716 $USD; RR 1.1; p < 0.001). Conversely, no statistically significant differences were observed in vascular complications (p = 0.3) or concerning in-hospital mortality (p = 0.1). Conclusions: After RP, patients with a history of heart valve replacement exhibited a higher rate of eight out of nine adverse in-hospital outcomes. However, these differences did not translate into higher in-hospital mortality. Full article
(This article belongs to the Special Issue Advances in Diagnosis and Treatment of Urological Cancers)
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