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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovations in the Clinical Management of Retinal Diseases: Emerging Therapies and Visual Rehabilitation

edited by

Francisco J. Povedano-Montero

submission deadline 20 Jun 2026 | 3 articles | Viewed by 4146 | Submission Open

Keywords: retinal diseases; macular degeneration; maculopathies; diabetic retinopathy; retinal vascular occlusions; retinitis pigmentosa

(This special issue belongs to the Section Ophthalmology)

Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition

edited by

Anna Olasińska-Wiśniewska

and Maciej Dąbrowski

submission deadline 20 Jun 2026 | 4 articles | Viewed by 4083 | Submission Open

Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; transcatheter aortic valve replacement

(This special issue belongs to the Section Cardiovascular Medicine)

Parkinson's Disease: Recent Advances in Diagnosis and Treatment

edited by

Mariachiara Sensi

and

Fabiana Colucci

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3997 | Submission Open

Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

Autoimmune Diseases and Multisystem Inflammation: Pathophysiology and Therapeutic Strategies

edited by

Tsuyoshi Shirai

submission deadline 20 Jun 2026 | 2 articles | Viewed by 3765 | Submission Open

Keywords: autoimmune diseases; cardiovascular diseases; cutaneous diseases; gastrointestinal diseases; pulmonary diseases; renal diseases; systemic manifestation; rheumatoid arthritis; systemic lupus erythematosus; vasculitis

(This special issue belongs to the Section Immunology & Rheumatology)

State of the Art in Cardiac Surgery: Progress, Challenges and Opportunities

edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3662 | Submission Open

Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts

(This special issue belongs to the Section Cardiology)

Risk Factors in Neonatal Intensive Care

edited by

Gabriela C. Zaharie

and

Melinda Matyas

submission deadline 20 Jun 2026 | 3 articles | Viewed by 3599 | Submission Open

Keywords: neonatal intensive care; infant birth; preterm; neonatal resuscitation; neonatal outcome; growth restriction; prenatal diagnosis; severe maternal pathology and its effects on a newborn; therapeutical hypothermia; parenteral nutrition; neonatal infection; retinopathy of prematurity

(This special issue belongs to the Section Clinical Pediatrics)

Hospital-Acquired Infections: Insights, Prevention, and Control Strategies

edited by

Andrea Fabbri

submission deadline 20 Jun 2026 | 4 articles | Viewed by 3273 | Submission Open

Keywords: healthcare-acquired infections; bloodstream infections; hospital‐acquired pneumonia; intestinal infections; clostridium difficile; surgical site infections; urinary tract infections; emergency department

(This special issue belongs to the Section Epidemiology & Public Health)

New Clinical Advances in Breast Reconstruction

edited by

Nobuyuki Mitsukawa

submission deadline 20 Jun 2026 | 4 articles | Viewed by 3131 | Submission Open

Keywords: breast reconstruction; autologous (flap) reconstruction; implant-based reconstruction; microsurgery and perforator flaps; robotic surgery/endoscopic surgery; fat grafting (lipofilling); patient-reported outcomes; reconstructive surgical innovation

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Advances in Scoliosis and Spinal Disorders: Diagnosis and Management

edited by Tejas Subramanian

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2918 | Submission Open

Keywords: spine surgery; adult spinal deformity; frailty; sarcopenia; muscle health; postoperative recovery; patient-reported outcomes

(This special issue belongs to the Section Orthopedics)

New Perspectives in Maternal–Fetal Medicine

edited by Catalina de Paco-Matallana

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2862 | Submission Open

Keywords: maternal– fetal medicine; prenatal diagnostics; fetal therapy; precision medicine; neonatal outcomes; maternal health

(This special issue belongs to the Section Obstetrics & Gynecology)

Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice

edited by

Stefano Figliozzi

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2833 | Submission Open

Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse

(This special issue belongs to the Section Cardiology)

Innovations in Neurorehabilitation—2nd Edition

edited by

Syoichi Tashiro

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2698 | Submission Open

Keywords: clinical neurophysiology; neuroengineering; robotics; non-invasive transcranial brain stimulation; spinal stimula-tion; regenerative rehabilitation; neuroimaging; brain– computer interface; brain-spinal interface; virtual reality; higher-level cognitive functions; vision rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Clinical Advances in the Pharmacotherapy of Diabetes

edited by Jonathan Watanabe,

Joshua J. Neumiller

and

Cheyenne Frazier

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2695 | Submission Open

Keywords: diabetes; microvascular complications; macrovascular complications; diabetes technology; pharmacoepidemiology; care delivery; novel therapies

(This special issue belongs to the Section Pharmacology)

Current Perspectives and Innovations in Urogynecology

edited by

Stavros Athanasiou

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2639 | Submission Open

Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Cardiovascular Rehabilitation: The Central Role of Exercise in Prevention and Care

edited by Massimo Pistono

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2510 | Submission Open

Keywords: cardiac rehabilitation; secondary prevention; physical exercise; cardiovascular health; aerobic exercise; cardio-oncology rehabilitation

(This special issue belongs to the Section Cardiovascular Medicine)

Multiple Myeloma: Therapeutic and Management Strategies

edited by Terri Parker

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2024 | Submission Open

Keywords: multiple myeloma; frontline treatment; monoclonal antibodies; sequencing of treatment; immunotherapy; CAR T; Bi-specific T cell engagers; toxicity management

(This special issue belongs to the Section Hematology)

Clinical Insights in Pediatric Dentistry

edited by

Giulia Orilisi

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1891 | Submission Open

Keywords: pediatric dentistry; caries management; dental trauma; preventive dentistry; behavior management; interdisciplinary care; clinical innovations

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current Challenges and Perspectives in Liver Transplantation

edited by Bogdan Dorobanţu,

Umberto Cillo

and Waldo Concepcion

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1886 | Submission Open

Keywords: liver transplantation; liver surgery; liver cirrhosis; liver disease; alcoholic and non-alcoholic steatohepatitis; cholangiocarcinoma; hepatocellular carcinoma; auxiliary liver transplantation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advanced Endoscopy and Imaging in Gastrointestinal Diseases

edited by

Iancu Dana Monica

and

Paul-Andrei Ștefan

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1739 | Submission Open

Keywords: advanced endoscopy; gastrointestinal imaging; minimally invasive therapy; early diagnosis; image-guided intervention; surgical planning; patient outcomes; gastrointestinal diseases

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Stroke in Patients with Atrial Fibrillation: Risk, Manifestation and Prevention

edited by

Iwona Gorczyca-Głowacka

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1727 | Submission Open

Keywords: anticoagulant treatment; atrial fibrillation; arrhythmia; personalized medicine; stroke

(This special issue belongs to the Section Cardiology)

Stroke Care: From Acute Interventions to Long-Term Recovery

edited by

Aikaterini Theodorou

and

Georgios Tsivgoulis

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1575 | Submission Open

Keywords: cerebrovascular diseases; acute ischemic stroke; intravenous thrombolysis; endovascular thrombectomy; intracerebral hemorrhage; etiology; cerebral amyloid angiopathy; stroke rehabilitation

(This special issue belongs to the Section Clinical Neurology)

Plastic and Reconstructive Surgery of the Face: Chances and Challenges

edited by

Cristian Trâmbițaș

and Bogdan Andrei Suciu

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1516 | Submission Open

Keywords: facial plastic surgery; facial reconstruction procedures; tissue regeneration; esthetic facial procedures; digital imaging and customization; biomaterials in reconstructive surgery; flap surgery innovations; microsurgical precision techniques

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Research on Minimally Invasive Spine Surgery

edited by Daniel Fahim

submission deadline 20 Jun 2026 | 3 articles | Viewed by 1475 | Submission Open

Keywords: minimally invasive spine surgery; spine tumors; spine trauma; spine fractures; lumbar stenosis; lumbar spondylolisthesis; lumbar disc herniation; lumbar radiculopathy; thoracic disc herniations; cervical radiculopathy

(This special issue belongs to the Section Orthopedics)

Clinical Advances and Challenges in Liver Transplantation: 3rd Edition

edited by

Paola Aceto

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1465 | Submission Open

Keywords: liver transplantation (LT); elderly donors; steatotic livers; donors after circulatory death (DCD); hepatocellular carcinoma (HCC); perioperative management

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Research Advances in Gynecologic Oncology

edited by

Maciej Skrzypczak

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1318 | Submission Open

Keywords: ovarian cancer; endometrial cancer; breast cancer; molecular biology; gynecological cancers

(This special issue belongs to the Section Oncology)

Bronchoscopy and Interventional Pulmonology

edited by Bryan S. Benn and

Jonathan Kurman

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1317 | Submission Open

Keywords: navigation-guided bronchoscopy; Robotic-guided bronchoscopy; 3D imaging integration; lung nodule/peripheral pulmonary lesion marking; transbronchial lung cryobiopsy and interstitial lung disease; malignant and benign central airway obstruction and stenosis; airway stents; pleuroscopic procedures; bronchoscopic lung volume reduction

(This special issue belongs to the Section Respiratory Medicine)

Oral and Maxillofacial Surgery: Clinical Progress, Challenges and Opportunities

edited by Janet Hayes Southerland and Leslie Robin Halpern

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1235 | Submission Open

Keywords: OMFS; surgery; research; innovation; interdisciplinary; cosmetic; pharmacology; cancer; repair; nerve; TMJ; rehabilitation; orthognathic; disorder; bleeding

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Chronic Kidney Disease: From Diagnosis to Treatment

edited by Debra Hain

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1165 | Submission Open

Keywords: chronic kidney disease; type 2 diabetes; diabetic complications; hemodialysis; nephrology nursing; older adults; palliative care; therapy; hypertension

(This special issue belongs to the Section Nephrology & Urology)

New Insights into Transcatheter Mitral Valve Therapy

edited by Antonio Sisinni and

Rodrigo Estévez-Loureiro

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1150 | Submission Open

Keywords: mitral regurgitation; transcatheter mitral valve therapy; TEER; TMVR; MitraClip; pascal; valve-in-valve; multimodality imaging; outcomes; structural heart interventions

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances and Future Challenges for Occupational Health

edited by

Gabriele D’Ettorre

and Vincenza Pellicani

submission deadline 20 Jun 2026 | 3 articles | Viewed by 1109 | Submission Open

Keywords: work-related disease; precision medicine; gender differences; aging workforce; preventive strategies

(This special issue belongs to the Section Epidemiology & Public Health)

Clinical Rehabilitation Strategies and Exercise for Stroke Recovery

edited by

Dimitrios I. Tsiptsios

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1102 | Submission Open

Keywords: stroke; stroke rehabilitation; exercise; biomarkers; rehabilitation outcomes

(This special issue belongs to the Section Clinical Rehabilitation)

Neuroimmunological Disorders: Mechanisms and Therapies

edited by

Christos Bakirtzis

and

Marina Kleopatra Boziki

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1102 | Submission Open

Keywords: neuroinflammatory; multiple sclerosis; neuromyelitis optica spectrum disorders; mog associated disease; autoimmune/paraneoplastic encephalitis

(This special issue belongs to the Section Clinical Neurology)

Advances in Peripheral Vascular Disease: Diagnosis, Management and Surgical Interventions

edited by Nikolaos Zacharias

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1076 | Submission Open

Keywords: atherosclerosis; peripheral artery disease; claudication; critical limb threatening ischemia; infrainguinal bypass; femoral stenting

(This special issue belongs to the Section Vascular Medicine)

The Treatment of BPO with Minimal Invasive Approach

edited by

Lukas Lusuardi

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1063 | Submission Open

Keywords: benign prostatic obstruction (BPO); prostatectomy; non-muscle invasive bladder cancer; muscle invasive bladder cancer; robotic surgery

(This special issue belongs to the Section Nephrology & Urology)

Cardiovascular Disease in the Elderly: Cardiogeriatric Assessment, Prevention, Treatment Outcomes and Perspectives

edited by Georgia Vamvakou

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1008 | Submission Open

Keywords: cardiovascular diseases; elderly patients; cardiogeriatric assessment; diagnosis and therapeutic planning; healthy aging; digital medicine

(This special issue belongs to the Section Cardiovascular Medicine)

Recent Progress in Anterior Cruciate Ligament Injury and Reconstruction

edited by Patrick Weninger

submission deadline 20 Jun 2026 | 1 articles | Viewed by 959 | Submission Open

Keywords: anterior cruciate ligament; ACL reconstruction; ACL repair; ACL preservation; orthobiologics; stem cells; rehabilitation

(This special issue belongs to the Section Sports Medicine)

Atrial Fibrillation and Its Complications: Preventive Strategies and Relative Evidence—2nd Edition

edited by Roberto Galea

submission deadline 20 Jun 2026 | 1 articles | Viewed by 943 | Submission Open

Keywords: atrial fibrillation; catheter ablation; oral anticoagulation; left atrial appendage closure; stroke prevent

(This special issue belongs to the Section Cardiology)

New Advances in Oral and Facial Surgery: 2nd Edition

edited by

Olindo Massarelli

submission deadline 20 Jun 2026 | 1 articles | Viewed by 927 | Submission Open

Keywords: squamous cell carcinoma; oro-pharyngeal tumors; skin tumors; plastic and reconstructive surgery; facial plastic surgery; facial reanimation; facial nerve palsy; head and neck surgery; maxillofacial surgery; aesthetic surgery; orthognatic surgery; dental implant surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Endoscopic Innovations in Gastrointestinal Diseases: From Diagnosis to Therapy

edited by Mattia Brigida and Gianluca Andrisani

submission deadline 20 Jun 2026 | 1 articles | Viewed by 912 | Submission Open

Keywords: endoscopic innovation; gastrointestinal diseases; advanced endoscopic imaging; therapeutic endoscopy; artificial intelligence; minimally invasive therapy; personalized medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Novel Insights into the Use of Artificial Intelligence in Clinical Medicine

edited by Sharon C. Kiang and Roger T. Tomihama

submission deadline 20 Jun 2026 | 1 articles | Viewed by 904 | Submission Open

Keywords: artificial intelligence; disease predictive models; wearable technology; surgical innovation; molecular targeting; big data science; machine learning; deep learning

Clinical Advances in Endocarditis: From Diagnosis to Treatment

edited by Ram Sharony and Katia Orvin

submission deadline 20 Jun 2026 | 2 articles | Viewed by 887 | Submission Open

Keywords: endocarditis; infective endocarditis; prosthetic valve endocarditis; TAVR endocarditis; advanced cardiac imaging

(This special issue belongs to the Section Cardiology)

Cardiotoxicity Within Cardio-Oncology: Clinical Advances from Prediction to Management

edited by

Massimiliano Camilli

submission deadline 20 Jun 2026 | 1 articles | Viewed by 818 | Submission Open

Keywords: cardio-oncology; cardiotoxicity; cancer therapy– related cardiac dysfunction; heart failure in cancer patients; biomarkers; multimodality imaging; risk stratification; cardioprotection; cancer survivors' care; multidisciplinary approach

(This special issue belongs to the Section Cardiology)

The New Era of Urological Surgery: Technology-Enhanced Clinical Outcomes

edited by

Razvan-George Rahota

and

Guillaume Ploussard

submission deadline 20 Jun 2026 | Viewed by 756 | Submission Open

Keywords: urology; surgery; robotic surgery; artificial intelligence; urological cancer

(This special issue belongs to the Section Nephrology & Urology)

Obsessive–Compulsive Disorder: Clinical Advances and Future Perspectives—Second Edition

edited by Andrea Fagiolini

submission deadline 20 Jun 2026 | 1 articles | Viewed by 679 | Submission Open

Keywords: obsessions– compulsions; anxiety; OCD symptoms; treatment options; functional impairment

(This special issue belongs to the Section Mental Health)

Orthopedic Oncology Updates and Controversial Issues

edited by Yehuda Kollender and Ron Batash

submission deadline 20 Jun 2026 | Viewed by 606 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; oligometastatic; atypical behavior tumor; cryosurgery; rare diseases; surgery; radiation therapy; immunotherapy; chemotherapy

(This special issue belongs to the Section Orthopedics)

Arterial Stiffness and Cardiovascular Risk: New Advances and Challenges

edited by

Andrea Grillo

submission deadline 20 Jun 2026 | 1 articles | Viewed by 573 | Submission Open

Keywords: arterial stiffness; vascular aging; anti-inflammation; cardiovascular risk; personalized medicine

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Rhinosinusitis and Nasal Polyposis: From Emerging Trends and Therapeutic Opportunities to Surgery

edited by Gian Luca Fadda, Giovanni Cavallo and

Giuseppe Guida

submission deadline 20 Jun 2026 | 1 articles | Viewed by 537 | Submission Open

Keywords: nasal polyps; chronic rhinosinusitis; asthma; endoscopic sinus surgery; anatomical variation; biologic treatment; type-2 inflammation; paranasal sinuses; CRSwNP; late response; long term; remission; dupilumab; control

(This special issue belongs to the Section Otolaryngology)

Applications of Artificial Intelligence in Cardiology: New Tools to Transform Care

edited by

Constantinos Bakogiannis

submission deadline 20 Jun 2026 | Viewed by 536 | Submission Open

Keywords: artificial intelligence in cardiology; machine learning; deep learning; AI-driven ECG analysis; cardiovas-cular imaging and AI; predictive analytics in cardiology; mHealth and wearables; clinical decision support systems; ethics and AI in healthcare; digital health and remote monitoring

(This special issue belongs to the Section Cardiology)

Physiotherapy and Therapeutic Exercise in Modern Clinical Practice

edited by Andoni Carrasco Uribarren,

Luis Ceballos-Laita

and

Carolina Climent-Sanz

submission deadline 20 Jun 2026 | 1 articles | Viewed by 505 | Submission Open

Keywords: exercise therapy; physiotherapy; therapeutic exercise; musculoskeletal disorders; musculoskeletal rehabilitation; pain management; patient-centered care; physiotherapy; rehabilitation technology

(This special issue belongs to the Section Orthopedics)

Pediatric Ophthalmology: Current Progress and Future Options

edited by

Claudia Yahalom

and

Nir Erdinest

submission deadline 20 Jun 2026 | Viewed by 404 | Submission Open

Keywords: pediatric ophthalmology; genetic eye diseases; gene therapy; genetic counseling; telemedicine; diagnostic tools; blindness in childhood; congenital cataract; visual rehabilitation; myopia control

(This special issue belongs to the Section Ophthalmology)

Displaying special issue 151-200 on page 4 of 31.

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