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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancing Neonatal Seizures and Epilepsy: New Perspectives and Interventions
edited by and Gaetano Cantalupo
submission deadline 25 Jun 2026 | 1 articles | Viewed by 1640 | Submission Open
Keywords: neonatal seizures; neonatal epilepsy; neonatal EEG; automated EEG analysis; neonatal brain monitoring; genetic; precision medicine; genetic epilepsies; genome; exome
(This special issue belongs to the Section Clinical Pediatrics)
Advances in Immunohematology: From Pathophysiology to Tailored Treatments submission deadline 25 Jun 2026 | 1 articles | Viewed by 1576 | Submission Open
Keywords: autoimmune cytopenia; hemophagocytic lymphohistiocytosis; inborn errors of immunity; lymphoproliferative diseases; malignancy; monoclonal antibodies; secondary immunodeficiency; vaccination
(This special issue belongs to the Section Immunology & Rheumatology)
Technological Advancements and Clinical Innovations in Diagnostic and Interventional Radiology: 2nd Edition submission deadline 25 Jun 2026 | 2 articles | Viewed by 1491 | Submission Open
Keywords: artificial intelligence; radiomics; image fusion; spectral computed tomography; functional magnetic resonance im-aging; CO2 angiography; balloon-occluded transcatheter arterial chemoembolization
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Recent Clinical Advances in Cardiac Rehabilitation: 2nd Edition
edited by
submission deadline 25 Jun 2026 | 1 articles | Viewed by 1321 | Submission Open
Keywords: cardiac rehabilitation; kinesiotherapy; psychological support; lifestyle modifications; myocardial infarction; heart failure
(This special issue belongs to the Section Cardiology)
Cardiometabolic Disease and Atherosclerosis: Epidemiology, Prevention, Diagnosis, and Clinical Treatment—2nd Edition
edited by and Konstantinos Mourouzis
submission deadline 25 Jun 2026 | 1 articles | Viewed by 1175 | Submission Open
Keywords: atherosclerosis; obesity; cardiometabolic disease; prevention; diabetes mellitus; endothelium; arteriosclerosis; coronary artery disease
(This special issue belongs to the Section Cardiology)
Clinical Management of Traumatic Brain Injury
edited by Adam James Wells and Peter Hutchinson
submission deadline 25 Jun 2026 | 1 articles | Viewed by 1084 | Submission Open
Keywords: traumatic brain injury; clinical management TBI; neurocritical care; neuromonitoring; trauma neurosurgery; artificial intelligence
(This special issue belongs to the Section Clinical Neurology)
Bariatric Surgery: Current Status and Emerging Clinical Trends
edited by Collin E. M. Brathwaite
submission deadline 25 Jun 2026 | 1 articles | Viewed by 893 | Submission Open
Keywords: bariatric surgery; metabolic surgery; obesity; GLP-1 receptor agonists; robotic surgery; revisional surgery; weight regain; metabolic mechanisms; enhanced recovery; surgical innovation
(This special issue belongs to the Section General Surgery)
Diagnosis and Management of Corneal Diseases
edited by Nicola Cardascia
submission deadline 25 Jun 2026 | 1 articles | Viewed by 871 | Submission Open
Keywords: corneal surgery; lamellar keratoplasty; bioengineered corneal grafts; regenerative medicine; cell-based therapies; tissue-based therapies; Intraoperative imaging; corneal wound healing; lmmune modulation; graft survival; translational research; multimodal diagnostics; clinical outcomes; corneal transparency restoration; ophthalmic surgical innovation
(This special issue belongs to the Section Ophthalmology)
Current Concepts and Clinical Application of Echocardiography
edited by
submission deadline 25 Jun 2026 | 1 articles | Viewed by 834 | Submission Open
Keywords: echocardiography; clinical echocardiography; advanced echocardiography; cardiovascular disease; clinical cardiology
(This special issue belongs to the Section Cardiology)
Multidisciplinary Care in Severe Traumatic Brain Injury Across the Continuum of Care: Acute, Rehabilitative, and Chronic Management
edited by Ryan Martin, Davin Quinn and Nicholas Race
submission deadline 25 Jun 2026 | 1 articles | Viewed by 673 | Submission Open
Keywords: severe traumatic brain injury; multidisciplinary; rehabilitation; advance practice providers; ancillary health; therapy; neuropsychology; nutrition
(This special issue belongs to the Section Brain Injury)
Upper Airway Management in Obstructive Sleep Apnea: Latest Advances and Future Perspectives
edited by Shintaro Chiba
submission deadline 25 Jun 2026 | 1 articles | Viewed by 452 | Submission Open
Keywords: obstructive sleep apnea (OSA); sleep surgery; upper airway stimulation (UAS); upper airway physiology
(This special issue belongs to the Section Respiratory Medicine)
Advanced Image-Enhanced Endoscopy and Colonoscopy
edited by , and Simona Di Caro
submission deadline 25 Jun 2026 | Viewed by 358 | Submission Open
Keywords: gastrointestinal endoscopy; colorectal cancer; endoscopic screening; artificial intelligence; chromoendoscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances of Aesthetic Plastic Surgery and Aesthetic Medicine
edited by Valentina Pinto and Rosalba Russo
submission deadline 25 Jun 2026 | Viewed by 344 | Submission Open
Keywords: aesthetic plastic surgery; aesthetic medicine; emerging technologies and devices in aesthetics; regenerative medicine and surgery; vulvovaginal surgery; complications in aesthetic medicine
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
IgA Nephropathy: Clinical Updates and Prospects
edited by
submission deadline 25 Jun 2026 | Viewed by 309 | Submission Open
Keywords: pathogenesis of IgA nephropathy; novel therapies; role of complement system; risk factors for disease progression; proteomic approach; serologic biomarkers; histological classification
(This special issue belongs to the Section Nephrology & Urology)
Myocardial Infarction: Clinical Management and Future Options
edited by
submission deadline 25 Jun 2026 | Viewed by 294 | Submission Open
Keywords: myocardial infarction; percutaneous coronary intervention; optimal medical therapy; clinical outcomes; cardiogenic shock; mechanical cardiac support device
(This special issue belongs to the Section Cardiology)
Diet and Nutritional Aspects in Cardiovascular-Kidney-Metabolic Diseases (CKM)
edited by Krishnaswami Vijayaraghavan
submission deadline 25 Jun 2026 | Viewed by 274 | Submission Open
Keywords: cardiovascular-kidney-metabolic diseases (CKM); obesity; diabetes and metabolic syndrome; dietary factors; nutritional aspects; food policy and food security; chronic kidney disease; heart disease; technology
(This special issue belongs to the Section Clinical Nutrition & Dietetics)
Integrating Artificial Intelligence and Contextual Factors in Emergency Care
edited by Ancor Sanz-García and
submission deadline 25 Jun 2026 | Viewed by 255 | Submission Open
Keywords: emergency care; artificial intelligence; early warning systems; data-driven healthcare; predictive analytics
(This special issue belongs to the Section Emergency Medicine)
Advances in Minimally Invasive and Endoscopic Neurosurgery
edited by Shunsuke Shibao
submission deadline 25 Jun 2026 | Viewed by 252 | Submission Open
Keywords: minimally invasive; endoscopic; keyhole; endonasal; transorbital; skull base; complications; surgical outcomes; technical innovations; robotic neurosurgery
(This special issue belongs to the Section Clinical Neurology)
Surgical Innovations in Pediatric Orthopedics
edited by
submission deadline 25 Jun 2026 | Viewed by 244 | Submission Open
Keywords: pediatric orthopedics; surgical innovation; growth modulation; absorbable implant; 3D printing
(This special issue belongs to the Section Orthopedics)
Human Immunodeficiency Virus: From Clinical Studies to Patient Outcomes
edited by Vítor Duque
submission deadline 25 Jun 2026 | Viewed by 221 | Submission Open
Keywords: HIV/AIDS; clinical trials; patient outcomes; clinical translational research
(This special issue belongs to the Section Infectious Diseases)
Clinical Advancements in Laparoscopic Surgery for Gastrointestinal Diseases
edited by
submission deadline 25 Jun 2026 | Viewed by 213 | Submission Open
Keywords: laparoscopic surgery; minimally invasive surgery; gastrointestinal diseases; colorectal cancer; gastric cancer; robotic surgery; fluorescence imaging; endoscopic-laparoscopic hybrid surgery; surgical oncology; future perspectives
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cancer Prevention and Early Detection: Epidemiological Approaches and Public Health Strategies submission deadline 25 Jun 2026 | Viewed by 202 | Submission Open
Keywords: cancer prevention; cancer screening; risk factors; cancer treatment; health information systems; cancer registry; cancer inequalities
(This special issue belongs to the Section Epidemiology & Public Health)
Coronary Artery Bypass Grafting: Contemporary Clinical Research Update submission deadline 25 Jun 2026 | 1 articles | Viewed by 195 | Submission Open
Keywords: coronary artery bypass grafting; arterial grafts; graft patency; hybrid coronary revascularization; perioperative management; outcomes research; risk stratification; frailty; minimally invasive/robotic CABG; antithrombotic therapy
(This special issue belongs to the Section Cardiology)
Acute Kidney Injury: Latest Advances and Prospects
edited by and Kianoush Kashani
submission deadline 26 Jun 2026 | 7 articles | Viewed by 9301 | Submission Open
Keywords: acute kidney injury (AKI); sepsis; septic shock; renal replacement therapy; intensive care; specialized interventions; biomarkers; risk factors; “ Green Practice” ; nephrology; epidemiology; multidisciplinary approach
(This special issue belongs to the Section Nephrology & Urology)
Multifactorial Causation and Therapies of Myopia: 2nd Edition submission deadline 26 Jun 2026 | 1 articles | Viewed by 1841 | Submission Open
Keywords: epidemiology; genetics; premyopia; simple and pathological myopia; orthokeratology; lenses for myopia control; blue light and red light; binocular vision and ocular optics; artificial intelligence
(This special issue belongs to the Section Ophthalmology)
Advances in General and Regional Anaesthesia
edited by Michał Jan Stasiowski, and
submission deadline 26 Jun 2026 | 1 articles | Viewed by 1146 | Submission Open
Keywords: general anaesthesia; regional anaesthesia; ropivacaine; bupivacaine; postoperative pain; postoperative nausea and vomiting; preventive analgesia; rescue opioid analgesia; total intravenous anaesthesia; inhalational anaesthesia
(This special issue belongs to the Section Anesthesiology)
Imaging and Molecular Biomarkers: The New Approach to Degenerative Retinal Diseases submission deadline 28 Jun 2026 | 4 articles | Viewed by 4052 | Submission Open
Keywords: ophthalmology; degenerative retinal diseases; imaging biomarkers; multimodal imaging; OCT; OCT angiography; molecular biomarkers; precision medicine; translational ophthalmic research
(This special issue belongs to the Section Ophthalmology)
Advances in Gene Therapy for Retinal Diseases
edited by Tahreem Aman Mir
submission deadline 28 Jun 2026 | 1 articles | Viewed by 2095 | Submission Open
Keywords: gene therapy; inherited retinal degenerations; age-related macular degeneration; diabetic retinopathy
(This special issue belongs to the Section Ophthalmology)
Youth Sports Injuries: From Prevalence to Prevention
edited by Swarup Mukherjee and
submission deadline 30 Jun 2026 | 4 articles | Viewed by 17027 | Submission Open
Keywords: youth sports injuries; musculoskeletal injuries; injury prevention; sport safety; youth athletes
(This special issue belongs to the Section Sports Medicine)
Pregnancy Complications and Maternal-Perinatal Outcomes
edited by
submission deadline 30 Jun 2026 | 5 articles | Viewed by 5815 | Submission Open
Keywords: pregnancy; high-risk; GDM; preeclampsia; fetal growth restriction; diabetes; placenta; ultrasound
(This special issue belongs to the Section Obstetrics & Gynecology)
Children and Adolescent Mood Disorders: Risks and Treatment submission deadline 30 Jun 2026 | 1 articles | Viewed by 2799 | Submission Open
Keywords: emotional dysregulation; mood disorders; adolescence; anxiety; depression; addiction; psychotherapy; pharmacological treatments; prevention programs
(This special issue belongs to the Section Mental Health)
The Atrial Fibrillation–Heart Failure Interconnection: Challenges and Innovations in Diagnosis and Treatment submission deadline 30 Jun 2026 | 1 articles | Viewed by 1485 | Submission Open
Keywords: atrial fibrillation; catheter ablation; ventricular dysfunction; myocardial remodeling; diastolic dysfunction; biomarkers; anti-arrhythmia agents; risk assessment; artificial intelligence; telemedicine
(This special issue belongs to the Section Cardiovascular Medicine)
Ergonomics and Low Back Pain: Integrative Approaches to Prevention, Assessment and Management submission deadline 30 Jun 2026 | 1 articles | Viewed by 1382 | Submission Open
Keywords: advanced in diagnostic methods; therapeutic innovations; multidisciplinary and personalized care models; prevention and rehabilitation; non-pharmacological strategies; ergonomics; biomechanics
(This special issue belongs to the Section Orthopedics)
Advanced Technologies, Concepts, and Topics in Modern Neurosurgery
edited by and Ralf Stroop
submission deadline 30 Jun 2026 | 1 articles | Viewed by 1112 | Submission Open
Keywords: modern neurosurgery; virtual reality; augmented reality; intraoperative imaging; neuronavigation; artificial intelligence; machine learning; robotic surgery; 3D printing; neurovascular interventions; neuro-oncology; skull base surgery; functional neurosurgery; spinal neurosurgery; surgical innovation; image-guided surgery; personalized neurosurgical planning
(This special issue belongs to the Section General Surgery)
New Clinical Insights into Acute Respiratory Failure submission deadline 30 Jun 2026 | 1 articles | Viewed by 914 | Submission Open
Keywords: acute respiratory failure; pathophysiology; advances respiratory monitoring; respiratory support strategies; respiratory mechanics; mechanical ventilation; respiratory drive; patient-ventilator asynchrony
(This special issue belongs to the Section Intensive Care)
Metastatic Colorectal Cancer Beyond Second-Line Treatment
edited by Jacopo Giuliani
submission deadline 30 Jun 2026 | 1 articles | Viewed by 861 | Submission Open
Keywords: metastatic colorectal cancer; subsequent lines; chemotherapy; targeted agents; radiotherapy; local therapy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications
edited by and
submission deadline 30 Jun 2026 | Viewed by 291 | Submission Open
Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications
(This special issue belongs to the Section Mental Health)
Robotic-Assisted Hepato-Pancreato-Biliary (HPB) Surgery: Advances and Clinical Perspectives
edited by and Riccardo Memeo
submission deadline 30 Jun 2026 | Viewed by 267 | Submission Open
Keywords: liver surgery; pancreatic surgery; HPB surgery; robotic surgery; robotic systems; advances in HPB surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Aortic Disease and Revascularization: 2nd Edition
edited by Andrej Udelnow
submission deadline 30 Jun 2026 | Viewed by 210 | Submission Open
Keywords: aortic disease; aortic aneurysm; endovascular aortic repair; atherosclerosis; aortic dissections; overall survival; quality of life; intravascular ultrasound
(This special issue belongs to the Section Vascular Medicine)
Integrating a One Health Approach into Antimicrobial Stewardship and Shared Care in Wound Management
edited by Joanna F. Blackburn
submission deadline 30 Jun 2026 | Viewed by 205 | Submission Open
Keywords: antimicrobial stewardship; antimicrobial resistance; one health; shared care; wound care; wound care management; chronic wound care; acute wound care; digital health; wound diagnostics; antimicrobials; antibiotics
(This special issue belongs to the Section Dermatology)
Advances in Anterior Cruciate Ligament Injury Treatment
edited by Goran Vrgoč
submission deadline 1 Jul 2026 | 3 articles | Viewed by 1326 | Submission Open
Keywords: anterior cruciate ligament (ACL) injury; ACL reconstruction techniques; nonoperative ACL treatment; ACL graft; knee biomechanics; return-to-sport assessment; ACL rehabilitation; neuromuscular and proprioceptive training; athletic injuries; performance-enhancing substances; reinjury prevention; psychological readiness; ACL performance testing; osteoarthritis risk
(This special issue belongs to the Section Orthopedics)
Modern Challenges in Pediatric Endocrinology: From Growth Disorders to Metabolic Dysregulation
edited by Katarzyna A. Majewska and Piotr Fichna
submission deadline 2 Jul 2026 | 1 articles | Viewed by 613 | Submission Open
Keywords: growth hormone deficiency; growth hormone therapy; short stature; obesity; obesity complications; obesity treatment; insulin resistance; prediabetes; type 1 diabetes; type 2 diabetes; hypothyroidism; hyperthyroidism; autoimmune thyroiditis; puberty disorders
(This special issue belongs to the Section Clinical Pediatrics)
Advances in Tuberculosis: Comprehensive Insights and Management Strategies
edited by Aliaksandr Skrahin
submission deadline 5 Jul 2026 | 4 articles | Viewed by 5103 | Submission Open
Keywords: pulmonary and extra-pulmonary tuberculosis (TB); TB epidemiology; TB screening; TB prevention; TB diagnostics; TB treatment; TB co-infections (e.g.; HIV; Hepatitis B and C); TB co-morbidities (e.g.; diabetes); host and Mycobacteria genetic; molecular mechanisms and genotype/phenotype correlations
(This special issue belongs to the Section Infectious Diseases)
Advances in Diagnosis and Management of Pancreatobiliary Disorders—2nd Edition
edited by
submission deadline 9 Jul 2026 | 10 articles | Viewed by 9189 | Submission Open
Keywords: pancreas diseases; pancreatic tumors; biliary tract diseases and neoplams; ERCP; EUS; cholangioscopy
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Treatment and Management of Rheumatic Diseases, Autoinflammatory Diseases, and Autoimmune Disorders
edited by Merav Lidar and
submission deadline 10 Jul 2026 | 8 articles | Viewed by 13713 | Submission Open
Keywords: rheumatic diseases; autoinflammatory diseases; autoimmune disorders; rheumatoid arthritis; diagnosis
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Challenges of Pelvic Floor Disorders Management
edited by
submission deadline 10 Jul 2026 | 4 articles | Viewed by 7929 | Submission Open
Keywords: pelvic floor disorders; pelvic organ prolapse; urinary incontinence; surgery; diagnostics; pelvic pain; vulvodynia; urinary tract symptoms; mesh-related complications
(This special issue belongs to the Section Obstetrics & Gynecology)
Heart Failure and Coronary Artery Diseases: Cardiovascular Complications and Comorbidities submission deadline 10 Jul 2026 | 3 articles | Viewed by 6823 | Submission Open
Keywords: heart failure; acute myocardial infarction; coronary artery diseases; cardiac imaging; biomarkers; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Management for Coronary Artery Disease and Revascularization
edited by Mohammad Reza Movahed
submission deadline 10 Jul 2026 | 3 articles | Viewed by 6651 | Submission Open
Keywords: coronary artery disease; coronary syndrome; stenting; revascularization; cardiovascular
(This special issue belongs to the Section Cardiovascular Medicine)
New Insights into Skin Tumors: From Pathogenesis to Therapy
edited by Loredana Ungureanu and Simona C. Şenilǎ
submission deadline 10 Jul 2026 | 4 articles | Viewed by 5659 | Submission Open
Keywords: skin tumors; pathogenesis; diagnosis; personalized medicine; therapeutic strategies; dermato-oncology
(This special issue belongs to the Section Dermatology)
New Clinical Advances in Pancreatobiliary Diseases
edited by
submission deadline 10 Jul 2026 | 3 articles | Viewed by 4941 | Submission Open
Keywords: pancreatobiliary diseases; EUS; ERCP; interventional endoscopy; targeted therapy; pancreatobiliary cancer
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
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