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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Optical Diagnostics for Head and Neck: Current Trends and Future Directions

edited by

Waseem Jerjes

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2533 | Submission Open

Keywords: head and neck cancer; head and neck surgery; fluorescence imaging; Raman spectroscopy; optical coherence tomography; photoacoustic imaging; photodiagnosis; photodynamic therapy

(This special issue belongs to the Section Otolaryngology)

Challenges in Minimally Invasive Colorectal and Abdominal Wall Surgery

edited by Francesco Ferrara and

Roberto Peltrini

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2511 | Submission Open

Keywords: colorectal surgery; laparoscopy; abdominal wall surgery; hernia; diastasis recti; surgical oncology; rectal tumor; colon tumor; colorectal neoplasia

(This special issue belongs to the Section General Surgery)

Prevention, Diagnosis and Treatment of Oral Mucosal Diseases

edited by

Masanobu Abe

submission deadline 31 Jul 2025 | 3 articles | Viewed by 2372 | Submission Open

Keywords: oral mucosal diseases; oral mucositis; oral precancerous lesions; oral cancer; oral potentially malignant disorders; OPMDs; oral leukoplakia

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Male Fertility in the Modern Age: Challenges and Opportunities

edited by Angelo Marino

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2330 | Submission Open

Keywords: male infertility; semen parameters; sperm selection; IVF/ICSI

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Advances in Diagnosis, Risk Stratification, and Personalized Management in Acute Coronary Syndromes

edited by Efstratios Karagiannidis, Barbara P. Fyntanidou and Aikaterini Apostolopoulou

submission deadline 31 Jul 2025 | 2 articles | Viewed by 2205 | Submission Open

Keywords: acute coronary syndrome (ACS); cardiovascular disease (CVD); ischemic heart disease; emergency medicine; risk stratification; personalized treatment; antiplatelets; primary and secondary prevention

(This special issue belongs to the Section Cardiology)

Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition

edited by

Joaquín Moya-Angeler

and

Francisco Forriol

submission deadline 31 Jul 2025 | 3 articles | Viewed by 1997 | Submission Open

Keywords: knee; knee replacement; knee arthroplasty; knee alignment technique; robotic knee arthroplasty

(This special issue belongs to the Section Orthopedics)

Clinical Advances in Assessment Measures and Theoretical Models of Caregivers' Sensitivity and Contingency: 2nd Edition

edited by

Silvia Cimino

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1906 | Submission Open

Keywords: clinical caregiving; sensitivity assessment; contingency modeling; caregiver– patient interactions; mental health outcomes; novel assessment measures; therapeutic responsiveness; caregiver interventions; clinical well-being; care recipient support

(This special issue belongs to the Section Intensive Care)

Artificial Intelligence and Machine Learning in Clinical Practice: Advancing Medical Imaging Analysis

edited by Guillaume Herpe

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1690 | Submission Open

Keywords: artificial intelligence; effectiveness; transformative impact; patient-centered radiology; workflows

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Recent Clinical Research on Nonalcoholic Fatty Liver Disease: 2nd Edition

edited by Gerond V. Lake-Bakaar

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1579 | Submission Open

Keywords: NAFLD; NASH; cirrhosis; hepatocellular carcinoma; hepatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Sustaining Success Through Innovation in Kidney Transplantation

edited by Junji Uchida

submission deadline 31 Jul 2025 | 2 articles | Viewed by 1357 | Submission Open

Keywords: kidney transplantation; long-term graft survival; immunosuppression; organ shortage; post-transplant complication

(This special issue belongs to the Section Nephrology & Urology)

Diagnostic and Therapeutic Pathways in Cardiac Heart Failure

edited by

Vincenzo Ezio Santobuono

and

Andrea Igoren Guaricci

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1282 | Submission Open

Keywords: heart failure; cardiomyopathies; pharmacologic therapies; device therapies; biomarkers; genetic testing; sudden cardiac death; cardiac MRI

(This special issue belongs to the Section Cardiology)

Sports Injuries: Recent Advances in Prevention and Rehabilitation, 2nd Edition

edited by

Stasinopoulos Dimitrios

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1279 | Submission Open

Keywords: sports injuries; treatment; musculoskeletal disorders; rehabilitation; physical rehabilitation; exercise science; sports science; injury prevention

(This special issue belongs to the Section Sports Medicine)

Diagnosis and Treatment of Salivary Gland Tumors: Current Advances and Future Options

edited by

Masaaki Higashino

submission deadline 31 Jul 2025 | 1 articles | Viewed by 1154 | Submission Open

Keywords: salivary gland tumor; facial nerve; functional preservation; preoperative diagnosis; ultrasonography; intraoperative nerve monitoring; extracapsular dissection; endoscopic surgery; neck dissection; facial nerve reconstruction; anticancer therapy; postoperative radiation therapy; frey syndrome; first bite syndrome; rehabilitation

(This special issue belongs to the Section General Surgery)

Clinical Advances in Minimally Invasive Urologic Surgery

edited by

Umberto Carbonara

, Fabio Crocerossa and

Savio Domenico Pandolfo

submission deadline 31 Jul 2025 | 1 articles | Viewed by 815 | Submission Open

Keywords: urology; uro-oncology; uro-gynecology; robotic surgery; laparoscopy; robot-assisted; artificial intelligence

(This special issue belongs to the Section Nephrology & Urology)

Clinical Advances in Autoimmune Disorders

edited by

Chiara Pellicano

and

Edoardo Rosato

submission deadline 31 Jul 2025 | 1 articles | Viewed by 812 | Submission Open

Keywords: systemic sclerosis; Raynaud’ s phenomenon; digital ulcers; scleroderma renal crisis; pulmonary arterial hypertension; interstitial lung disease; fibrosis

(This special issue belongs to the Section Immunology)

Application of Artificial Intelligence in Cardiology

edited by

Matthias Unterhuber

submission deadline 31 Jul 2025 | 1 articles | Viewed by 685 | Submission Open

Keywords: artificial intelligence; cardiology; clinical practice; valvular heart disease; arrhythmias; device therapy; machine learning

(This special issue belongs to the Section Cardiology)

Foot and Ankle Surgery: Current Advances and Prospects

edited by

Jaeho Cho

submission deadline 31 Jul 2025 | 1 articles | Viewed by 676 | Submission Open

Keywords: foot and ankle surgery; foot pathologies; ankle disease and trauma; diabetic foot; epidemiology; clinical anatomy; foot orthoses; weight-bearing CT

(This special issue belongs to the Section Orthopedics)

Clinical Investigations into Diagnosing and Managing Strabismus

edited by Mario Cantó Cerdán and Pilar Cacho-Martínez

submission deadline 31 Jul 2025 | 1 articles | Viewed by 587 | Submission Open

Keywords: oculomotricity; binocular vision; strabismus; ocular motility disorders; exotropia; esotropia; video oculography; eye tracker; ocular deviation

(This special issue belongs to the Section Ophthalmology)

Clinical Insights into Pediatric Critical Care

edited by Katherine Biagas and Daniel E Sloniewsky

submission deadline 31 Jul 2025 | 1 articles | Viewed by 510 | Submission Open

Keywords: PICU; anemia; blood transfusion; critically ill children; traumatic hemorrhage

(This special issue belongs to the Section Intensive Care)

Hip Fracture and Surgery: Clinical Updates and Challenges

edited by

Norio Imai

submission deadline 31 Jul 2025 | 1 articles | Viewed by 382 | Submission Open

Keywords: antiosteoporosis medication; fracture liaison service; osteosynthesis; total hip arthroplasty; hemiarthroplasty

(This special issue belongs to the Section Orthopedics)

Novel Developments on Diagnosis and Treatment of Atrial Fibrillation

edited by

Elena Bobescu

and Mihaela-Viviana Ivan

submission deadline 31 Jul 2025 | 1 articles | Viewed by 314 | Submission Open

Keywords: atrial fibrillation; supraventricular arrhythmia; cardiovascular risk; oxidative stress; inflammation

(This special issue belongs to the Section Cardiovascular Medicine)

Machine Learning and Artificial Intelligence in Neurosurgery

edited by Jan Oliver Neumann and

Paul Naser

submission deadline 31 Jul 2025 | Viewed by 314 | Submission Open

Keywords: artificial intelligence; neurosurgery; neuro-oncology; spinal neurosurgery; neuro-ICU; stereotactic neurosurgery; pre-operative planning

(This special issue belongs to the Section Clinical Neurology)

Kidney Transplantation: Challenges, Advances and Lessons Learnt

edited by Karim Soliman and

Tibor Fülöp

submission deadline 31 Jul 2025 | Viewed by 237 | Submission Open

Keywords: kidney transplantation; nephrology; transplant medicine; patient selection criteria; immunosuppressive treatment; long-term outcomes; graft survival; complication; multi-organ transplant consideration; innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Treatment for Venous Thromboembolism

edited by

Elisavet Grouzi

and Georgia Kaiafa

submission deadline 31 Jul 2025 | Viewed by 205 | Submission Open

Keywords: venous thromboembolism; anticoagulation; cancer-associated thrombosis; thrombosis in MPNs; thrombosis in multiple myeloma; antiphospholipidic syndrome; thrombosis in PNH; thrombosis in hemoglobinopathies; thrombophilia; pregnancy and thrombophilia; reversal of anticoagulants; thromboprophylaxis

(This special issue belongs to the Section Hematology)

Heart Failure and Its Complications: Advances in Clinical Diagnosis and Management, 2nd Edition

edited by

Michael J. Bonios

submission deadline 31 Jul 2025 | Viewed by 203 | Submission Open

Keywords: heart failure; complications; arrhythmias; pharmacological therapy; devices; mechanical circulatory support

(This special issue belongs to the Section Cardiology)

Hand Surgery Clinical Advances and Practice Updates

edited by Guy Rubin

submission deadline 31 Jul 2025 | Viewed by 200 | Submission Open

Keywords: trauma; mallet; burn; nerve; tendon

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Clinical Management and Treatment of Psoriasis

edited by

Luciano Ibba

submission deadline 31 Jul 2025 | Viewed by 179 | Submission Open

Keywords: psoriasis; biological drugs; personalized medicine; comorbidities; real-world evidence

(This special issue belongs to the Section Dermatology)

Clinical Outcomes in Urologic Oncology

edited by

Francesco Claps

submission deadline 31 Jul 2025 | Viewed by 175 | Submission Open

Keywords: urologic oncology; surgical oncology; bladder cancer; upper tract urothlial carcinoma; prostate cancer; testis cancer; penile cancer; immunotherapy; chemotherapy; stereotactic body radiotherapy

(This special issue belongs to the Section Nephrology & Urology)

Advanced Diagnostic and Therapeutic Strategies for Sarcoidosis

edited by

Małgorzata Sobiecka

and

Monika Szturmowicz

submission deadline 31 Jul 2025 | Viewed by 172 | Submission Open

Keywords: sarcoidosis; cardiac sarcoidosis; pulmonary fibrosis; magnetic resonance imaging; FDG-PET/CT; echocardiography; neurosarcoidosis; differential diagnosis; hypercalcaemia; IGRA; sarcoidosis-associated pulmonary hypertension; fatigue; corticosteroids; metotrexat; infliximab; antifibrotic treatment; lung transplantation; artificial intelligence; broncho-alveolar lavage; cytokines

(This special issue belongs to the Section Respiratory Medicine)

Disorders of Consciousness in Ischemic Stroke: Evaluation, Management and Prognostic Implications

edited by

Shraddha Mainali

submission deadline 31 Jul 2025 | Viewed by 158 | Submission Open

Keywords: disorders of consciousness; ischemic stroke; prognosis; coma; neuroprognostication

(This special issue belongs to the Section Clinical Neurology)

Haemophilia: Current Treatment and Clinical Outcomes, Challenges and Opportunities: 2nd Edition

edited by

Ezio Zanon

submission deadline 31 Jul 2025 | Viewed by 142 | Submission Open

Keywords: haemophilia A and B; FVIII EHL; FIX EHL; prophylaxis; emicizumab; health-related quality of life; population pharmacokinetics

(This special issue belongs to the Section Hematology)

State of the Art in Surgical Treatment for Colorectal Cancer

edited by Saulius Švagždys

submission deadline 31 Jul 2025 | Viewed by 123 | Submission Open

Keywords: laparoscopic and robotic surgery; endoscopic and minimally invasive surgery; colorectal cancer; energy devices; staplers

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Shaping Modern Gastroenterology: Bridging Advancements in Digestive Endoscopy and Clinical Research

edited by Manuele Furnari and Stefano Kayali

submission deadline 3 Aug 2025 | Viewed by 137 | Submission Open

Keywords: digestive endoscopy; gastrointestinal disorders; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); therapeutic endoscopy; artificial intelligence; pancreatic and biliary diseases; small bowel pathology; early neoplastic lesions; inflammatory bowel diseases (IBDs); translational gastroenterology; endoscopic submucosal dissection (ESD); per-oral endoscopic myotomy (POEM); endoscopic imaging; gastrointestinal pathophysiology

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) as a Global but Not Liver-Limited Health Challenge—from Disease Pathogenesis to Therapeutic Targets

edited by Beata Kasztelan-Szczerbinska and Halina Cichoż-Lach

submission deadline 5 Aug 2025 | 2 articles | Viewed by 2697 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease (MASLD); non-alcoholic fatty liver disease (NAFLD); hepatic steatosis; multiorgan metabolic interactions; liver-related morbidity; liver-related mortality; lipid metabolism; cardiovascular metabolic complications; metabolic dysfunction-related cancer

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Prevention, Management, and Rehabilitation of Head and Neck Injuries

edited by

Giovanni Barassi

, Pier Enrico Gallenga and

Roberta Di Pietro

submission deadline 5 Aug 2025 | 1 articles | Viewed by 977 | Submission Open

Keywords: neck injuries; whiplash injuries; head injuries; concussion; neck pain; cervicalgia; post-concussive syndrome; post-concussive symptoms; vision disorders; hearing disorders; emergency care; emergency therapies; physical medicine and rehabilitation; musculoskeletal rehabilitation; sports medicine

(This special issue belongs to the Section Sports Medicine)

Clinical Advances in Artificial Intelligence in Urology

edited by

Theodoros Tokas

submission deadline 10 Aug 2025 | 5 articles | Viewed by 5726 | Submission Open

Keywords: artificial intelligence; deep learning; artificial neural networks; computer; AI; machine learning

(This special issue belongs to the Section Nephrology & Urology)

State of the Art: Catheter Ablation of Atrial Fibrillation

edited by

Roberto Menè

and Cinzia Monaco

submission deadline 10 Aug 2025 | 3 articles | Viewed by 5332 | Submission Open

Keywords: atrial fibrillation; catheter ablation; pulsed-field ablation; supraventricular arrhythmias; atrial substrate

(This special issue belongs to the Section Cardiovascular Medicine)

The Clinical Role of Imaging in Lung Diseases

edited by

Isabelle Fitton

and Claire Van Ngoc Ty

submission deadline 10 Aug 2025 | 4 articles | Viewed by 3707 | Submission Open

Keywords: lung screening; lung cancer; acute respiratory distress; pulmonary embolism; chronic obstructive pulmonary disease; imaging

(This special issue belongs to the Section Respiratory Medicine)

Immune Dysregulation in Inborn Errors of Immunity: From Allergy to Autoimmunity and Lymphoproliferation

edited by

Giorgio Costagliola

submission deadline 10 Aug 2025 | 2 articles | Viewed by 3023 | Submission Open

Keywords: immune dysregulation; immunodeficiency; autoimmunity; allergy; lymphoproliferation; inborn errors of immunity

(This special issue belongs to the Section Immunology)

Clinical Updates and Perspectives of Implant Dentistry

edited by

Renzo Guarnieri

and

Rodolfo Reda

submission deadline 13 Aug 2025 | 1 articles | Viewed by 4228 | Submission Open

Keywords: osseointegration; soft tissue integration; peri-implant diseases

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Management of Patients with Heart Failure—2nd Edition

edited by

Tudoran Cristina

submission deadline 13 Aug 2025 | 6 articles | Viewed by 3575 | Submission Open

Keywords: acute heart failure; chronic heart failure; treatment options; management of heart failure; life style changes; diagnosis of heart failure

(This special issue belongs to the Section Cardiovascular Medicine)

Trends and Prospects in Shoulder and Elbow Surgery

edited by Lorenzo Diaz Balzani, Erika Albo,

Rocco Papalia

and

Vincenzo Denaro

submission deadline 14 Aug 2025 | 4 articles | Viewed by 4942 | Submission Open

Keywords: shoulder; elbow; arthroplasty; arthroscopy; rehabilitation; trauma; minimally invasive; regenerative medicine; implant technology

(This special issue belongs to the Section Orthopedics)

Amyloid: From Heart to Brain

edited by

Filippos Triposkiadis

Andrew Xanthopoulos

and

Alexandros Briasoulis

submission deadline 15 Aug 2025 | 4 articles | Viewed by 3852 | Submission Open

Keywords: amyloid; heart; brain; interactions; small vessel disease; takotsubo; Alzheimer’ s disease

(This special issue belongs to the Section Cardiology)

Sepsis: Current Updates and Perspectives

edited by Ecaterina Scarlatescu

submission deadline 15 Aug 2025 | 2 articles | Viewed by 2981 | Submission Open

Keywords: sepsis biomarkers; diagnostic tools; cytokines; inflammation; infection; antibiotherapy; blood purification; novel therapies

(This special issue belongs to the Section Intensive Care)

Novel Therapeutic Strategies for Acute Myeloid Leukemia

edited by Giovangiacinto Paterno and

Maria Ilaria Del Principe

submission deadline 15 Aug 2025 | 2 articles | Viewed by 2377 | Submission Open

Keywords: acute myeloid leukemia; novel treatments; supportive care; quality of life; patients’ outcomes; targeted therapy

(This special issue belongs to the Section Hematology)

Otolaryngology—Head and Neck Surgery: Current Trends and Challenges

edited by

Michele Gaffuri

and Lorenzo Maria Gaini

submission deadline 15 Aug 2025 | 3 articles | Viewed by 1415 | Submission Open

Keywords: minimally invasive surgery; endoscopy; exoscopy; airway surgery; salivary glands diseases; otitis media; pediatric otolaryngology; head and neck surgery

(This special issue belongs to the Section Otolaryngology)

Oral and Maxillofacial Radiology: Clinical Progress and New Directions

edited by Zbigniew Serafin and

Wojciech Kazimierczak

submission deadline 15 Aug 2025 | 3 articles | Viewed by 1395 | Submission Open

Keywords: artificial intelligence (AI); computed-assisted diagnosis (CAD); cone beam computed tomography (CBCT); convolutional neural network (CNN); computed tomography (CT); magnetic resonance (MR); PET-CT

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Cardiac Electrophysiology: Focus on Clinical Practice

edited by

Andreas Müssigbrodt

submission deadline 15 Aug 2025 | 1 articles | Viewed by 878 | Submission Open

Keywords: cardiomyopathy; arrhythmia; heart rhythm; atrial fibrillation; ventricular tachycardia; sudden cardiac death; mapping; ablation; pulsed field ablation (PFA); device; pacemaker; left bundle branch area pacing (LBBAP); conduction system pacing (CSP); implantable cardioverter-defibrillator (ICD); leadless pacing; extraction

(This special issue belongs to the Section Cardiology)

Application of Magnetic Resonance Imaging (MRI) in the Diagnosis, Staging and Follow-Up of Oncological Diseases

edited by

Matteo Bonatti

submission deadline 15 Aug 2025 | 1 articles | Viewed by 767 | Submission Open

Keywords: MRI; cancer; oncology; diagnosis; staging; follow-up; radiomics

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Diagnosis and Treatment for Bone Tumor

edited by Antonio Ziranu and Luigi Cianni

submission deadline 15 Aug 2025 | 1 articles | Viewed by 495 | Submission Open

Keywords: bone tumor; oncology; osteosarcoma; chondrosarcoma; megaprosthesis; bone resection; chemotherapy; radiotherapy; sarcoma; custom-made

(This special issue belongs to the Section Orthopedics)

Displaying special issue 201-250 on page 5 of 29.

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