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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Personalized Treatments for Glaucoma Patients

edited by Gloria Roberti

submission deadline 20 Sep 2025 | 3 articles | Viewed by 3583 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); optic nerve damage; visual field loss; ophthalmoscopy; angle closure glaucoma; open-angle glaucoma; primary glaucoma; secondary glaucoma; normal-tension glaucoma; pigmentary glaucoma

(This special issue belongs to the Section Ophthalmology)

Clinical Advancements in Spine Surgery: Best Practices and Outcomes

edited by

Mitsuru Yagi

submission deadline 20 Sep 2025 | 5 articles | Viewed by 3501 | Submission Open

Keywords: adult spinal deformity; scoliosis; frailty; biological age; big data analysis

(This special issue belongs to the Section Orthopedics)

Corneal Diseases and Corneal Transplantation: Current Updates and Perspectives

edited by Itay Lavy and

Nir Erdinest

submission deadline 20 Sep 2025 | 5 articles | Viewed by 3228 | Submission Open

Keywords: corneal diseases; corneal transplantation; imaging techniques; pharmacological in-terventions; surgical interventions; tissue engineering

(This special issue belongs to the Section Ophthalmology)

Diabetic Nephropathy: Current Standards and Future Directions

edited by

Alaa S. Awad

Emaad M. Abdel-Rahman

and Charles W. Heilig

submission deadline 20 Sep 2025 | 1 articles | Viewed by 2397 | Submission Open

Keywords: diabetic nephropathy: standard of care; diabetic nephropathy: future directions; SGLT2 in diabetic nephropathy; markers for diabetic nephropathy; diabetic nephropathy in the elderly; diabetic nephropathy in renal transplant patients; finerenone in diabetic nephropathy

(This special issue belongs to the Section Nephrology & Urology)

Advances in the Diagnosis and Treatment of Acute Kidney Injury

edited by Gianpaolo Reboldi and

Mario Bonomini

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1748 | Submission Open

Keywords: acute kidney injury; diagnosis; biomarkers; early detection; prognosis; renal replacement therapy

(This special issue belongs to the Section Nephrology & Urology)

The Current State of Robotic Surgery in Urology

edited by

Luca Di Gianfrancesco

submission deadline 20 Sep 2025 | 2 articles | Viewed by 1468 | Submission Open

Keywords: robotic surgery; urology; surgical technique; multi-port; single port; major urological surgery; reconstructive surgery; robot-assisted radical cystectomy; patients’ selection

(This special issue belongs to the Section Nephrology & Urology)

Updates in the Orthopedic Management of Foot Disorders: 2nd Edition

edited by

Carlo Biz

and

Pietro Ruggieri

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1431 | Submission Open

Keywords: foot pathologies; diabetic feet; forefoot deformities; oncology surgery; foot tumors; minimally invasive surgery; percutaneous surgery; foot joint arthroscopy; stress fractures

(This special issue belongs to the Section Orthopedics)

Hemophilia: Current Trends and Future Directions

edited by

Jonathan C. Roberts

and

Michael B. Nichol

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1203 | Submission Open

Keywords: hemophilia; prophylaxis; gene therapy; burden of illness; quality of life; patient reported outcomes; hemarthrosis; women and hemophilia

(This special issue belongs to the Section Hematology)

Foot Disorders: Multidisciplinary Perspectives on Prevention and Treatment

edited by Aksone L. Nouvong and Neil M. Paige

submission deadline 20 Sep 2025 | 1 articles | Viewed by 1045 | Submission Open

Keywords: foot deformities; minimally invasive surgery; foot/ankle joint arthroscopy; nail pathology; trauma; neuropathy; Charcot arthropathy; melanoma; tendon injury; fractures; peripheral vascular disease; diabetic foot infections; diabetic foot ulcer; lower limb amputation

(This special issue belongs to the Section Orthopedics)

Recent Advances in the Prevention, Treatment, and Rehabilitation of Sports Injuries

edited by Nili Steinberg

submission deadline 20 Sep 2025 | 1 articles | Viewed by 821 | Submission Open

Keywords: athletes; physical activity; sports; injuries; musculoskeletal; pain; rehabilitation; prevention; risk factors; functional abilities; muscle strength; joint range of motion (ROM); postural balance; ultrasonography maturation; adolescent

(This special issue belongs to the Section Sports Medicine)

Pancreatic Surgery: Clinical Practices and Challenges

edited by Guido Alsfasser and

Roberto Salvia

submission deadline 20 Sep 2025 | 1 articles | Viewed by 802 | Submission Open

Keywords: prognostic variables; surgical technique; outcome; timing of surgery; perioperative strategies; pancreatic cancer; pancreatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Thoracic Surgery: State of the Art and Future Directions

edited by

Ugo Cioffi

and

Marco Scarci

submission deadline 20 Sep 2025 | 1 articles | Viewed by 653 | Submission Open

Keywords: thoracic surgery; lung surgery; lung cancer; rib fractures; lung disease; pectus excavatum

(This special issue belongs to the Section Respiratory Medicine)

Advances in the Management of Intracranial Aneurysms

edited by Robert H. Rosenwasser, Nikolaos Mouchtouris and Elias Atallah

submission deadline 20 Sep 2025 | Viewed by 350 | Submission Open

Keywords: cerebral aneurysm; endovascular; open vascular; flow diversion; cerebral bypass; stent-assisted coiling

(This special issue belongs to the Section Clinical Neurology)

Laparoscopic Surgery: Challenges and Solutions in Clinical Practice

edited by

Giuseppe Cavallaro

and Alessia Fassari

submission deadline 20 Sep 2025 | Viewed by 209 | Submission Open

Keywords: laparoscopic surgery; minimally invasive surgery; surgical challenges; clinical practice; surgical training; robotic-assisted surgery; artificial intelligence in surgery; laparoscopic instrumentation; intraoperative complications; surgical innovation; skill enhancement; surgical outcomes

(This special issue belongs to the Section General Surgery)

Liquid Biopsies in Oral Cancer: Advances and New Perspectives

edited by

Óscar Rapado-González

submission deadline 20 Sep 2025 | Viewed by 209 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; liquid biopsies; saliva and blood biomarkers; circulating tumor cells (CTCs); cell-free DNA (cfDNA)/circulating tumor DNA (ctDNA); cell-free RNA (cfRNA); extracellular vesicles (EVs); genetic and epigenetic biomarkers; early detection; prognosis and therapy response prediction; precision medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

New Insights into the Management of Psoriasis and Cardiovascular Disease

edited by Amit Kumar Dey

submission deadline 20 Sep 2025 | Viewed by 115 | Submission Open

Keywords: psoriasis; psoriatic arthritis; inflammatory skin disease; chronic inflammation; cardiometabolic disease

(This special issue belongs to the Section Dermatology)

Aortic Aneurysms: Recent Advances in Diagnosis and Treatment

edited by Marco Virgilio Usai, Giuseppe Asciutto and Michele Piazza

submission deadline 23 Sep 2025 | 3 articles | Viewed by 2737 | Submission Open

Keywords: aortic aneurysms; abdominal aortic; thoraco-abdominal aortic aneurysms (TAAAs); complex aortic anatomies; endovascular abdominal aortic aneurysm repair (EVAR); endovascular thoracic aortic aneurysm repair (TEVAR); endovascular treatment

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Minimally Invasive Vascular Surgery

edited by Ben Li and

Mohammad Qadura

submission deadline 23 Sep 2025 | 1 articles | Viewed by 781 | Submission Open

Keywords: minimally invasive vascular surgery; endovascular surgery; angioplasty; stenting; atherectomy; robotics; peripheral vascular intervention; carotid stenting; transcarotid artery revascularization; endovascular aneurysm repair

(This special issue belongs to the Section Vascular Medicine)

Hypertension: Clinical Treatment and Management

edited by

José L. Flores-Guerrero

submission deadline 24 Sep 2025 | 2 articles | Viewed by 888 | Submission Open

Keywords: hypertension management; weight control; blood pressure monitoring; wearable technology; telemonitoring sys-tems; immune therapy; resistant hypertension; lifestyle interventions; cardiovascular health; advanced treatment strate-gies

(This special issue belongs to the Section Epidemiology & Public Health)

Endocrine Tumors: Diagnosis, Treatment, and Management

edited by

Jules T. Zhang-Yin

Francesco Dondi

and Emmanouil Panagiotidis

submission deadline 25 Sep 2025 | 8 articles | Viewed by 11343 | Submission Open

Keywords: neuroendocrine tumors; thyroid cancer; adrenal gland tumors; pituitary adenomas; parathyroid tumors; pancreatic neuroendocrine tumors; surgical management; radiotherapy

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Perspectives in Stroke Rehabilitation

edited by Krystyna Jaracz,

Karolina Filipska-Blejder

and Robert Ślusarz

submission deadline 25 Sep 2025 | 7 articles | Viewed by 10802 | Submission Open

Keywords: stroke; clinical perspectives; therapy; functional outcome predictors; rehabilitation; quality of life

(This special issue belongs to the Section Clinical Rehabilitation)

Pancreatic Cancer: Current and Emerging Treatment Options

edited by Eleonora Lai,

Nicola Silvestris

and

Mario Scartozzi

submission deadline 25 Sep 2025 | 2 articles | Viewed by 10364 | Submission Open

Keywords: pancreatic cancer; treatment options; emerging therapies; precision medicine; immunotherapy; targeted therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Sleep in Neurology—Sleep Disorders and Dysfunction of the Nervous System

edited by

Mariusz Siemiński

submission deadline 25 Sep 2025 | 5 articles | Viewed by 9282 | Submission Open

Keywords: sleep; neurology; insomnia; restless leg syndrome; REM sleep behavior disorder; parasomnia; somnambulism; neurodegenerative disorders; brain injury; sleep-related movement disorders

(This special issue belongs to the Section Clinical Neurology)

Ultrasound Diagnosis of Obstetrics and Gynecologic Diseases

edited by

Florian Recker

submission deadline 25 Sep 2025 | 7 articles | Viewed by 8991 | Submission Open

Keywords: obstetric ultrasound; gynecologic sonography; 3D/4D ultrasound imaging; fetal imaging techniques; prenatal screening; gynecologic oncology; ultrasound elastography; contrast-enhanced ultrasound; ultrasound in fertility; ultrasound training and education; clinical ultrasound standardization; diagnostic imaging in obstetrics and gynecology; personalized medicine in ultrasound diagnosis; ethical considerations in obstetric ultrasound; technological advancements in ultrasound imaging

(This special issue belongs to the Section Obstetrics & Gynecology)

Rehabilitation and Management of Stroke

edited by Thomas Platz

submission deadline 25 Sep 2025 | 4 articles | Viewed by 8824 | Submission Open

Keywords: stroke; rehabilitation; evidence; implementation; neurology; neurorehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Inborn Errors of Immunity: Advances in Diagnosis and Treatment

edited by Jolanta Bernatoniene

submission deadline 25 Sep 2025 | 2 articles | Viewed by 8791 | Submission Open

Keywords: inborn errors of immunity (IEI); primary immunodeficiencies (PID); chronic granulomatous disease; PIK3CD mutations; immunology; autoimmunity

(This special issue belongs to the Section Immunology)

Acute Respiratory Distress Syndrome (ARDS): Causes, Management, and Treatment

edited by Gabriele Sales and Francesca Collino

submission deadline 25 Sep 2025 | 3 articles | Viewed by 8773 | Submission Open

Keywords: acute respiratory distress syndrome; mechanical ventilation; lung-protective ventilation; extracorporeal membrane oxygenation; ventilator-induced lung injury; hypoxemia; rescue therapies; pronation; lung physiology; clinical outcome

(This special issue belongs to the Section Respiratory Medicine)

Current Advances in Endometriosis: An Update

edited by

Mislav Mikuš

, Mario Ćorić and

Antonio Simone Laganà

submission deadline 25 Sep 2025 | 6 articles | Viewed by 6957 | Submission Open

Keywords: endometriosis; gynecological diseases; adenomyosis; classification; diagnosis; treatment; alternative therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Interaction Between Systemic Diseases and Oral Diseases

edited by

Henk S. Brand

submission deadline 25 Sep 2025 | 5 articles | Viewed by 6436 | Submission Open

Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Moving Forward to New Trends in Pulmonary Diseases

edited by

Ramona Cioboata

and

Costin Teodor Streba

submission deadline 25 Sep 2025 | 5 articles | Viewed by 6193 | Submission Open

Keywords: pulmonary tuberculosis; chronic obstructive airway diseases; bronchiectasis; COVID-19; sleep apnea; ultrasound; lung cancer; pulmonary rehabilitation

(This special issue belongs to the Section Respiratory Medicine)

Innovations and Advances in Breast Cancer Research and Treatment

edited by

Palma Fedele

submission deadline 25 Sep 2025 | 4 articles | Viewed by 5883 | Submission Open

Keywords: breast cancer; early detection; genomics; personalized medicine; targeted therapies; survivorship; quality of life; artificial intelligence; machine learning; immunotherapy

(This special issue belongs to the Section Oncology)

Clinical Perspectives on Foot and Ankle Surgery

edited by Kenichiro Nakajima

submission deadline 25 Sep 2025 | 3 articles | Viewed by 4989 | Submission Open

Keywords: foot and ankle; minimally invasive surgery; surgical techniques; new technologies; diagnosis; clinical assessment

(This special issue belongs to the Section Orthopedics)

Surgical Treatment for Lung Cancer

edited by

Piotr Gabryel

, Cezary Piwkowski and Marek Ochman

submission deadline 25 Sep 2025 | 4 articles | Viewed by 4986 | Submission Open

Keywords: lung cancer; surgery; minimally invasive surgery; immunotherapy; enhanced recovery after surgery; segmentectomy

(This special issue belongs to the Section Respiratory Medicine)

Strategies for Preventing and Managing Postoperative Complications in Minimally Invasive Surgery

edited by Shingo Tsujinaka

submission deadline 25 Sep 2025 | 4 articles | Viewed by 4741 | Submission Open

Keywords: minimally invasive surgery; postoperative complications; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes

(This special issue belongs to the Section General Surgery)

Clinical Updates on Diabetes Mellitus and Carbohydrate Metabolism-Related Diseases

edited by

Tatsuya Fukuda

submission deadline 25 Sep 2025 | 2 articles | Viewed by 4350 | Submission Open

Keywords: diabetes; diabetic complications; cardiovascular disease; carbohydrate; endocrinology treatment strategies

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Advances in Valvular Heart Diseases

edited by

Mohammad Kassar

submission deadline 25 Sep 2025 | 3 articles | Viewed by 4051 | Submission Open

Keywords: prosthetic heart valve; heart valve pathophysiology; structural heart valve interventions; echocardiographic assessment; cardiovascular imaging; valvular heart disease; valvular regurgitation; valvular stenosis

(This special issue belongs to the Section Cardiology)

Infective Endocarditis: What Is New in the Clinical Research: 2nd Edition

edited by

Petros Ioannou

submission deadline 25 Sep 2025 | 2 articles | Viewed by 3749 | Submission Open

Keywords: infective endocarditis; vegetation; native valve; prosthetic valve; aortic valve; mitral valve; cardiac device; bloodstream infection; bacteremia

(This special issue belongs to the Section Cardiovascular Medicine)

Treatment of Bladder Cancer: From Past to Future

edited by

Jørgen Bjerggaard Jensen

submission deadline 25 Sep 2025 | 2 articles | Viewed by 3479 | Submission Open

Keywords: urology; bladder cancer; urothelial cancer; nonmuscle-invasive bladder cancer; muscle-invasive bladder cancer

(This special issue belongs to the Section Oncology)

Dentistry and Oral Surgery: Current Status and Future Prospects

edited by

Dragana Gabrić

Ivona Bago

and

Marko Vuletić

submission deadline 25 Sep 2025 | 2 articles | Viewed by 2901 | Submission Open

Keywords: dentistry; oral surgery; dental implantology; prosthodontics; restorative dentistry; periodontology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Gastric Cancer and Peritoneal Diseases

edited by

Shin Saito

submission deadline 25 Sep 2025 | 2 articles | Viewed by 2498 | Submission Open

Keywords: gastric cancer; peritoneal disease; conversion surgery; intraperitoneal chemotherapy; potential biomarker

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Biomarkers and Diagnostics in Neurological Diseases

edited by Maria Ioanna Stefanou

submission deadline 25 Sep 2025 | 2 articles | Viewed by 2489 | Submission Open

Keywords: biomarkers; neurological diseases; diagnosis; lipoprotein(a); neurofilament protein; tau peptide; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

Cardiac Surgery: Clinical Advances

edited by Carmelo Dominici, Giovanni Casali and

Antonio Nenna

submission deadline 25 Sep 2025 | 3 articles | Viewed by 1823 | Submission Open

Keywords: cardiac surgery; surgical innovation; minimally invasive techniques; robotic surgery; personalized medicine; advanced surgical technologies

(This special issue belongs to the Section Cardiology)

Anterior Cruciate Ligament (ACL) Injuries: Clinical Treatment and Rehabilitation

edited by Young-Jin Seo

submission deadline 25 Sep 2025 | 2 articles | Viewed by 1667 | Submission Open

Keywords: anterior cruciate ligament (ACL); reconstruction; lateral extra-articular procedures; all-inside technique; internal bracing; slope reducing osteotomy; biologic augmentation; rehabilitation

(This special issue belongs to the Section Orthopedics)

Airway Management: From Basic Techniques to Innovative Technologies

edited by Kunal Karamchandani and Sheila Nainan Myatra

submission deadline 25 Sep 2025 | 2 articles | Viewed by 1655 | Submission Open

Keywords: airway management; physiologically difficult airway; videolaryngoscopy; esophageal intubation; artificial intelligence

(This special issue belongs to the Section Intensive Care)

Advanced Approaches in Hip and Knee Arthroplasty

edited by Filippo Randelli and

Alberto Fioruzzi

submission deadline 25 Sep 2025 | 3 articles | Viewed by 1650 | Submission Open

Keywords: hip; hip surgery; knee arthroplasty; knee surgery; hip and knee arthroplasty

(This special issue belongs to the Section Orthopedics)

Post-Return of Spontaneous Circulation (Post-ROSC) Management for Out-of-Hospital Cardiac Arrest (OHCA) Patients: What We Can Do to Improve Survival and Return to Work and Participation in Society?

edited by

Enrico Baldi

submission deadline 25 Sep 2025 | 2 articles | Viewed by 1488 | Submission Open

Keywords: return of spontaneous circulation (ROSC); quality of life; psychological distress; post-ROSC management; return to society

(This special issue belongs to the Section Cardiology)

Diagnostic and Therapeutic Challenges in Infective Endocarditis

edited by Lorenzo Bertolino

submission deadline 25 Sep 2025 | 1 articles | Viewed by 1290 | Submission Open

Keywords: infective endocarditis; complications; diagnostic challenges; therapeutic approach; epidemiology; clinical correlates

(This special issue belongs to the Section Cardiology)

Intracranial Aneurysms: Diagnostics and Current Treatment

edited by Vincenzo Antonelli and

Roberto Colasanti

submission deadline 25 Sep 2025 | 1 articles | Viewed by 1145 | Submission Open

Keywords: neurovascular diseases; aneurysms; vascular malformations; diagnostic imaging; minimally invasive approaches; surgical techniques; endovascular interventions; treatment algorithms; subarachnoid hemorrhage; neurorehabiltation

(This special issue belongs to the Section Clinical Neurology)

Diagnosis and Surgical Treatment for Colorectal Cancer

edited by Nidal Issa, Wisam Khoury and Rachel Gingold-Belfer

submission deadline 25 Sep 2025 | 1 articles | Viewed by 1050 | Submission Open

Keywords: colorectal cancer; laparoscopy; colonoscopy; colectomy; diagnosis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Emerging Trends and Innovations in Restorative Dentistry: Advances in Clinical Practice

edited by

Oana Almasan

submission deadline 25 Sep 2025 | 1 articles | Viewed by 936 | Submission Open

Keywords: restorative dentistry; clinical practice; artificial intelligence; 3D printing; endodontics; prosthodontics; periodontics; dental surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Displaying special issue 201-250 on page 5 of 30.

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