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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Bioinformatics Study in Human Diseases: Integration of Omics Data for Personalized Medicine (Second Edition)

edited by

Hung-Yu Lin

and

Pei-Yi Chu

submission deadline 20 Jul 2025 | 5 articles | Viewed by 5348 | Submission Open

Keywords: cancers; ageing-related diseases; bioinformatics; multi-omics; pharmacogenetics; deep learning; evolutionary learning; diagnosis; prognosis; companion biomarker; drug screening; mechanism dissection

(This special issue belongs to the Section Molecular Informatics)

Abiotic Stresses in Plants: From Molecules to Environment—2nd Edition

edited by

Martin Bartas

submission deadline 20 Jul 2025 | 4 articles | Viewed by 5179 | Submission Open

Keywords: stress signaling; abiotic stress; oxidative stress; genotoxic stress

(This special issue belongs to the Section Molecular Plant Sciences)

Lung Diseases Molecular Pathogenesis and Therapy

edited by

Kazufumi Nakamura

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5106 | Submission Open

Keywords: lung diseases; drug therapy; chronic obstructive pulmonary disease; lung cancer; lung fibrosis; pulmonary hypertension; asthma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Chromatin Remodelers as Players and Drivers in Pathological States

edited by Matteo De March

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5082 | Submission Open

Keywords: protein structure/function; chromatin remodelers; DNA repair; oncogene/oncosuppressor; cancer

(This special issue belongs to the Section Molecular Biology)

Genomic Research of Rare Diseases

edited by Shira Rockowitz and Piotr Sliz

submission deadline 20 Jul 2025 | 5 articles | Viewed by 5082 | Submission Open

Keywords: rare disease ontology; variants of uncertain significance; candidate genes; whole genome sequencing; long read whole genome sequencing; machine learning; multi-omics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Linkage between Atherosclerosis and Extracellular Vesicles

edited by

Wioletta Olejarz

submission deadline 20 Jul 2025 | 2 articles | Viewed by 5017 | Submission Open

Keywords: atherosclerosis; extracellular vesicles; exosomes; vascular inflammation; stroke; biomarkers; miRNA; stem and progenitor cells; cardiovascular diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Application of Biomolecular Materials in Tissue Engineering

edited by

István Hornyák

submission deadline 20 Jul 2025 | 3 articles | Viewed by 5017 | Submission Open

Keywords: biomolecular materials; tissue engineering; material science; in vitro and in vivo biodegradation; cell culture; tissue regeneration; cell scaffold; biocompatible materials

(This special issue belongs to the Section Materials Science)

Chronic Obstructive Pulmonary Disease (COPD): From Pathogenesis to Therapy

edited by José M. Marin

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4980 | Submission Open

Keywords: COPD; COPD mechanisms; COPD pathology; COPD pharmacology; cytokine biology; biomarkers; early diagnosis; inflammation; COPD management; new therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Animal Research Model for Neurological Diseases, 2nd Edition

edited by

Giuseppe Montalbano

and

Sepand Rastegar

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4977 | Submission Open

Keywords: experimental models; mouse; rat; zebrafish; neurological disease; Alzheimer’ s disease; Parkinson’ s disease; neurodegeneration; neuroregeneration

(This special issue belongs to the Section Molecular Neurobiology)

Understanding Reproductive Health and Infertility: Molecular and Genetic Insights

edited by

Jan Tesarik

submission deadline 20 Jul 2025 | 4 articles | Viewed by 4903 | Submission Open

Keywords: sperm quality; oocyte quality; uterine receptivity

(This special issue belongs to the Section Molecular Biology)

The Role of Glia in Neuropsychiatric Disorders

edited by

Guillaume Lucas

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4809 | Submission Open

Keywords: glial cells; astrocytes; microglia; neuro-inflammation; synaptic plasticity; neuropsychiatric disorders

(This special issue belongs to the Section Molecular Neurobiology)

Recent Advances in Prevention, Diagnosis and Treatment of Pediatric Diseases

edited by

Giovanni Fiorito

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4784 | Submission Open

Keywords: pediatric diseases; bioinformatics; in utero and early-life exposures; multi-omic biomarkers; personalized medicine; diagnosis; prevention

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Inflammatory Signaling Pathways Involved in Gastrointestinal Diseases: Second Edition

edited by

Diana Di Liberto

and

Marianna Lauricella

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4720 | Submission Open

Keywords: inflammatory signaling pathways; gastrointestinal diseases; gastrointestinal cancer; inflammatory bowel disease; colonitis; colorectal cancer; cytokine

(This special issue belongs to the Section Molecular Immunology)

Functional Role of Non-coding RNAs in Cancer: Inside and outside Cells

edited by

Simone Anfossi

and

Linda Fabris

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4717 | Submission Open

Keywords: ncRNAs; gene expression regulation; biological functions; extracellular vesicles; intercellular communication; cancer progression; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Advances in Density Functional Theory and Related Methods for Molecular Computational Chemistry

edited by Paolo Umari

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4643 | Submission Open

Keywords: density functional theory; quantum chemistry; algorithms; quantum computing; high-performance computing; machine learning; many-body perturbations theory; quantum Monte Carlo

(This special issue belongs to the Section Molecular Informatics)

Molecular Mechanisms Underlying Vulnerability to Stress-Related Disorders

edited by Marta Pardo

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4615 | Submission Open

Keywords: stress-related disorders; post-traumatic stress disorder; molecular mechanisms; pharmacological targets

(This special issue belongs to the Section Molecular Neurobiology)

Genetic Basis of Autism Spectrum Disorder

edited by

Elisabetta Bolognesi

and

Franca Rosa Guerini

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4597 | Submission Open

Keywords: autism spectrum disorder (ASD); neurodevelopmental disorder (NDD); genetic causes of autism; genetic polymorphism; gene variant; genome-wide association studies; single nucleotide; polymorphism; precision medicine; genetic mutations; diagnostic marker

(This special issue belongs to the Section Molecular Genetics and Genomics)

Signaling Pathways and Novel Therapies in Heart Disease

edited by

Anindita Das

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4593 | Submission Open

Keywords: heart failure; arrhythmias; ischemic heart disease; myocardial regeneration; inflammation; gene- or cell-based therapy; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Marine Omics

edited by

Mónica Carrera

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4549 | Submission Open

Keywords: marine; seafood; omics; genomics; proteomics; transcriptomics; metabolomics; systems biology

(This special issue belongs to the Section Biochemistry)

Plasticity of the Nervous System after Injury: 2nd Edition

edited by

Xavier Navarro

and

Tessa Gordon

submission deadline 20 Jul 2025 | 4 articles | Viewed by 4533 | Submission Open

Keywords: neural plasticity; axonal regeneration; nerve injury; glial cells; central nervous system

(This special issue belongs to the Section Molecular Neurobiology)

Recent Research on Hypertension and Related Complications

edited by

Marijn Speeckaert

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4491 | Submission Open

Keywords: arterial hypertension; cardiovascular disease; pathophysiology; molecular mechanisms; complications

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Peroxisome and Lysosome in Health and Disease

edited by

Anne Vejux

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4479 | Submission Open

Keywords: peroxisomes; lysosomes; autophagy; lysosomal diseases; peroxidase; oxidative stress; acid hydrolase; lysosomal storage disease(LSD); gaucher disease

(This special issue belongs to the Section Molecular Biology)

NRF2/KEAP1 Signalling in Cancer

edited by

Sonia Fantone

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4476 | Submission Open

Keywords: oxidative stress; cancer; aging; senescence; inflammation; ovarian cancer; prostate cancer; antioxidants

(This special issue belongs to the Section Molecular Biology)

Pathways in Development and Disease: The Role of RNA Regulation in Biological and Pathological Events

edited by

Guilherme Tralhão

and

Rui Caetano Oliveira

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4381 | Submission Open

Keywords: RNA; human disease; cancer; diagnostic; therapy; development

(This special issue belongs to the Section Biochemistry)

Molecular Insights into Zoology

edited by

Valeria Maselli

submission deadline 20 Jul 2025 | 4 articles | Viewed by 4373 | Submission Open

Keywords: zoology; genomics; transcriptomics; phylogeny; molecular evolution; mtDNA; eDNA; RNA; molecular zoolog

(This special issue belongs to the Section Molecular Biology)

Advances in Molecular Forensic Pathology and Toxicology: An Update

edited by

Angelo Montana

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4357 | Submission Open

Keywords: biomarkers; immunohistochemistry; histopathology; forensic pathology; forensic toxicology; forensic biomarkers; toxicological biomarkers; neuropathology; mRNA; post-mortem interval; cerebral damage; in vitro; in vivo; and in silico models; hypoxic– ischemic brain injury; pregnancy biomarkers; vitality

(This special issue belongs to the Section Molecular Biology)

Transporters in Health and Disease

edited by

Giuliano Ciarimboli

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4262 | Submission Open

Keywords: transporters; disease; regulation; drugs; toxicity; signaling

(This special issue belongs to the Section Molecular Biology)

New Insights into Plant Pathology and Abiotic Stress

edited by

Shoupu He

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4210 | Submission Open

Keywords: plant pathology; abiotic stress; molecular mechanisms; stress resistance; signaling pathways; epigenetics; omics technologies; disease management; climate change; plant stress responses

(This special issue belongs to the Section Molecular Plant Sciences)

The Role of RNAs in Cancers: Recent Advances

edited by Roman Beňačka

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4187 | Submission Open

Keywords: cancer cells; carcinogenesis; mRNAs; ncRNAs; lncRNAs; miRNAs; circRNAs; piRNAs; RNA-based diagnostics; RNA-based therapy

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in Electrochemical-Related Materials

edited by Celia García-Hernandez

submission deadline 20 Jul 2025 | 4 articles | Viewed by 4185 | Submission Open

Keywords: novel electrochemical devices; advanced micro- and nanomaterials for electrochemical applications; batteries; fuel and photoelectrochemical cells; electrochemical sensors and biosensors; new advances in supercapacitors; electrochemical electrolyzers; advanced electrochemical materials for environmental applications

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms and Functions of Macrophage Cells

edited by Magdalena Król

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4171 | Submission Open

Keywords: macrophages; immune responses; inflammation; cancer; tumor microenvironment

(This special issue belongs to the Section Molecular Immunology)

Integrative Multi-Omics Analysis for Cancer Biomarkers

edited by

Youping Deng

and

Kurt K. Zhang

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4151 | Submission Open

Keywords: bioinformatics; biomedical informatics; cancer; genomics; systems biology

(This special issue belongs to the Section Molecular Oncology)

Advances in Agro-Polymers

edited by

In Chul Um

submission deadline 20 Jul 2025 | 2 articles | Viewed by 4133 | Submission Open

Keywords: cellulose; lignin; starch; fibroin; sericin; keratin; soy; zein; pectin; collagen; biocompatibility; biodegradability

(This special issue belongs to the Section Materials Science)

Vegetable Genetics and Genomics, 3rd Edition

edited by

Yunsong Lai

and

Xixiang Li

submission deadline 20 Jul 2025 | 4 articles | Viewed by 4087 | Submission Open

Keywords: major vegetable crops; genome; variome; genotyping; GWAS; QTL mapping; functional genome; metabolome; breeding target characters; genetic mechanism; functional genes

(This special issue belongs to the Section Molecular Plant Sciences)

Pediatric Diseases: From Molecular Mechanisms to Novel Therapeutic Strategies

edited by

Elena Tarca

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4053 | Submission Open

Keywords: congenital abnormalities; genetic disease; molecular mechanism; therapeutic agents; maternal and fetal medicine; pediatric diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Discovery of Microbial and Plant Specialized Metabolites

edited by

Marco Masi

submission deadline 20 Jul 2025 | 3 articles | Viewed by 4032 | Submission Open

Keywords: natural products; specialized metabolites; secondary metabolites; plant; pharmacology

(This special issue belongs to the Section Molecular Plant Sciences)

Non-small Cell Lung Cancer: From Molecular Mechanisms to Therapeutic Strategies

edited by Lorenzo Belluomini

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3976 | Submission Open

Keywords: NSCLC; predictive and prognostic biomarkers; immunotherapy; targeted therapy; special populations

(This special issue belongs to the Section Molecular Oncology)

Molecular Toxicity of Foodstuff Contaminants and Mitigation Strategies

edited by

Lihong Zhao

and Matthew Koci

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3940 | Submission Open

Keywords: antibiotics; heavy metals; pesticides; mycotoxins; foodborne pathogens; polycyclic aromatic hydrocarbons; microplastics; toxicity; biodegradation; detoxification

(This special issue belongs to the Section Molecular Toxicology)

Recent Advances in Molecular Targets for Treatment and Drug Delivery in Tumors

edited by

Emily Capone

submission deadline 20 Jul 2025 | 4 articles | Viewed by 3935 | Submission Open

Keywords: targeted therapy; tumor; molecular target; drug delivery; drug design

(This special issue belongs to the Section Molecular Oncology)

New Insights into Immune Dysregulation Disorders

edited by

Francesco Saettini

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3934 | Submission Open

Keywords: immune dysregulation disorders; autoimmune conditions; primary immunodeficiencies; autoinflammatory disorders

(This special issue belongs to the Section Molecular Immunology)

New Insights into the Immunopathology of Infectious Diseases

edited by Marta Camici

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3861 | Submission Open

Keywords: infection immunology; immune dysregulation in infectious diseases; interactions between infective agents and immune responses; modeling of the immune system; new pathways of pathogenesis

(This special issue belongs to the Section Molecular Immunology)

Beyond Digestion: The Role of Gut Microbiota in Metabolism, Immunity and Brain Function

edited by

Alip Borthakur

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3852 | Submission Open

Keywords: gut dysbiosis; gut microbiota; metabolism

(This special issue belongs to the Section Molecular Immunology)

Molecular Biology of Osteoporosis

edited by

Harish K. Datta

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3817 | Submission Open

Keywords: osteoporosis; bone; signalling; molecular; fractures; endocrine; paracrine

(This special issue belongs to the Section Molecular Biology)

Biomaterials for Drug Delivery and Advanced Therapies

edited by

Annalisa Bianchera

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3766 | Submission Open

Keywords: polymers; biomaterials; drug delivery; scaffold; ATMPs; tissue regeneration

(This special issue belongs to the Section Materials Science)

Novel Insights into Regenerative Medicine

edited by

Jorge U. Carmona

and

Marco Tatullo

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3754 | Submission Open

Keywords: regenerative medicine; tissue regeneration; stem cell; platelet-rich plasma; growth factors; cytokines; bioscaffolds; gels

(This special issue belongs to the Section Materials Science)

Advances, Pitfalls and Future Perspectives for CRISPR/Cas9 Mediated Genome Editing: 4th Edition

edited by

Alexander Kondrashov

and

Timofey S. Rozhdestvensky

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3734 | Submission Open

Keywords: molecular insights into different approaches and methods for CRISPR/Cas9 genome editing; the generation of disease models; the CRISPR/Cas9-mediated genome editing of ES cells; the CRISPR/Cas9 system in cancer biology; CRISPR/Cas9-mediated genome editing in model organisms (plants; fungi and animals); the CRISPR/Cas9 system in epigenetic research; the CRISPR/Cas9 system in gene therapy— applications and the challenges in the implementation of this technology; the CRISPR/Cas9 system beyond genome editing (molecular markers; biosensors; etc.)

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Amyloidosis in Pathobiology and Therapy

edited by

Kazufumi Nakamura

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3697 | Submission Open

Keywords: amyloidosis; ATTR; transthyretin; misfolding; molecular mechanisms; molecular therapeutic targets; molecular imaging; SPECT; tracers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Human Retrovirus Infection: 2nd Edition

edited by

Yosuke Maeda

Toshio Hattori

and Kotaro Shirakawa

submission deadline 20 Jul 2025 | 3 articles | Viewed by 3629 | Submission Open

Keywords: retrovirus; ATL; HIV-1; AIDS

(This special issue belongs to the Section Molecular Microbiology)

The Effect of Food-Derived Compounds on Brown Fat Cell Function

edited by

Nobuyuki Takahashi

submission deadline 20 Jul 2025 | 2 articles | Viewed by 3584 | Submission Open

Keywords: brown adipocyte; beige adipocyte; nutrients; food-derived components; thermogenesis; energy homeostasis; inflammation; obesity; diabetes; insulin resistance; metabolic syndrome; adipokines; lipid and carbohydrate metabolism

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Nanoparticles in Inhaled Drug Delivery

edited by

Nazrul Islam

submission deadline 20 Jul 2025 | 1 articles | Viewed by 3571 | Submission Open

Keywords: inhaled nanoparticles; inhaled antibacterial formulations and delivery; inhaled anticancer drugs; polymeric drug nanoparticles for lung delivery; controlled release of inhalable antibacterial/anticancer drugs and their toxicity

(This special issue belongs to the Section Materials Science)

Displaying special issue 1101-1150 on page 23 of 69.

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