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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Natural Compounds for Counteracting GI and Liver Diseases

edited by

Daniela Gabbia

and

Raquel Abalo

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5892 | Submission Open

Keywords: natural compounds; gastrointestinal diseases; liver diseases; pharmacological potential

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Exploring the Pathogenetic Mechanisms in Respiratory Virus Infections: Recent Advances and Future Directions

edited by

Marta De Angelis

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5723 | Submission Open

Keywords: respiratory viruses; virus-host interactions; inflammation; metabolic pathways

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Noncovalent Interactions and Applications in Materials and Catalysis

edited by Snežana D. Zarić

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5650 | Submission Open

Keywords: noncovalent interactions; materials; catalysis; crystal structures; quantum chemistry calculations; hydrogen bonds; stacking interactions; spectroscopy

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Editorial Board Members’ Collection Series: Autoimmune Diseases—2nd Edition

edited by

Yves Renaudineau

and

Dirk Roggenbuck

submission deadline 20 Sep 2025 | 5 articles | Viewed by 5530 | Submission Open

Keywords: autoimmunity; autoimmune diseases; immunotherapy; biomarkers; pathogenic mechanisms

(This special issue belongs to the Section Molecular Immunology)

Molecular Advances in Cell Proliferation, Senescence and Apoptosis

edited by

Chuanxi Cai

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5479 | Submission Open

Keywords: biological molecules; cell proliferation; senescence; apoptosis; human diseases

(This special issue belongs to the Section Molecular Biology)

The Role of Oxidative Stress and Antioxidants in Human Disease

edited by

Federica Mannino

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5392 | Submission Open

Keywords: oxidative stress; free radicals; antioxidants; reactive oxygen species (ROS); polyphenols

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Neurodegenerative Diseases and Inflammation: Pathogenesis, Biomarkers and Treatments

edited by

Luisa Agnello

and Anna Maria Ciaccio

submission deadline 20 Sep 2025 | 2 articles | Viewed by 5357 | Submission Open

Keywords: neurodegeneration; inflammation; biomarkers; Alzheimer’ s disease; molecular mechanism; pathogenesis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Advances in Stem Cells in Human Health and Diseases

edited by

Elisaveta N. Voynova

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5327 | Submission Open

Keywords: stem cells biology; iPSCs; hESC

(This special issue belongs to the Section Molecular Biology)

New Insights in Prion Diseases

edited by

Eva Bagyinszky

submission deadline 20 Sep 2025 | 1 articles | Viewed by 5262 | Submission Open

Keywords: prion diseases; prion mutation; genetic modifier; neurodegenerative diseases; therapy; neuroprotection

(This special issue belongs to the Section Molecular Neurobiology)

Biofunctional Coatings for Medical Applications

edited by

Liviu Duta

Valentina Grumezescu

and

Gabriela Dorcioman

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5166 | Submission Open

Keywords: biofunctional coatings; thin film deposition techniques; surface engineering; tissue engineering; materials’ doping and co-doping; medical applications

(This special issue belongs to the Section Materials Science)

Bacterial Adaptation Strategies to the Host: From Acute, Aggressive to Chronic, Dormant Infections, 2nd Edition

edited by

Bettina Löffler

submission deadline 20 Sep 2025 | 2 articles | Viewed by 5053 | Submission Open

Keywords: dormancy; phenotype switching; bacterial stress; survival strategies; persisters; resuscitation; starvation; cell cycle arrest; ATP homeostasis

(This special issue belongs to the Section Molecular Microbiology)

Emerging Advances in Cancer Biomarkers: Machine Learning, Radiomics, Genomics, and More

edited by

Hung-Yu Lin

and

Pei-Yi Chu

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5041 | Submission Open

Keywords: cancers; biomarkers; precision medicine; artificial intelligence; machine learning; radiomics; genomics; radiogenomics; multi-omics; pharmacogenetics

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advanced Synthetic Methodologies in Drug Development

edited by

Davide Moi

submission deadline 20 Sep 2025 | 3 articles | Viewed by 5035 | Submission Open

Keywords: organic chemistry; medicinal chemistry; catalysis; photo-catalysis; green chemistry; drug design; drug analysis; flow chemistry

(This special issue belongs to the Section Molecular Pharmacology)

Fish Immunology, 5th Edition

edited by

Alberto Cuesta

and

Elena Chaves-Pozo

submission deadline 20 Sep 2025 | 4 articles | Viewed by 5011 | Submission Open

Keywords: fish immunology; innate immunity; acquired immunity; leucocytes; disease; immunostimulants; immunodepression; inflammation

(This special issue belongs to the Section Molecular Immunology)

Cellular and Molecular Biology in the Compromised Neonate

edited by

Tim G. A. M. Wolfs

submission deadline 20 Sep 2025 | 1 articles | Viewed by 4952 | Submission Open

Keywords: compromised neonate; infections; placental dysfunction; disrupted oxygen supply; molecular and cellular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Musculoskeletal Disorders: From Molecular Pathology to Novel Therapeutic Approach

edited by

María Orosia Lucha López

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4898 | Submission Open

Keywords: joints; skeletal muscles; tendons; ligaments; fascia; articular cartilage; intervertebral discs; physiotherapy; novel therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Anti-Inflammatory Activity of Natural Products of Plant Origin

edited by Radoslaw Zajdel

submission deadline 20 Sep 2025 | 1 articles | Viewed by 4809 | Submission Open

Keywords: anti-inflammatory; phytochemicals; natural products; medicinal plants; inflammation; cytokines; NF-κ B pathway; cyclooxygenase inhibitors; flavonoids; terpenoids; polyphenols; molecular mechanisms; drug discovery; ethnopharmacology; metabolomics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

TRP Channels for Pain, Itch and Inflammation Relief: 2nd Edition

edited by

Arpad Szallasi

and

Ari-Pekka Koivisto

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4647 | Submission Open

Keywords: TRP channels; “ thermoTRP” channels; neuropathic pain; inflammatory pain; cancer pain; pruritic skin iseases; itch; neurogenic inflammation; migraine

(This special issue belongs to the Section Molecular Immunology)

Molecular Genetics and Breeding Mechanisms in Domestic Animals: 3rd Edition

edited by

Guiping Zhao

submission deadline 20 Sep 2025 | 4 articles | Viewed by 4616 | Submission Open

Keywords: animal genetics; animal breeding; functional genomics; multiomics analysis; molecular immunity; interactions between microbe and host

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Genetics of Breast Cancer—Recent Progress

edited by

Virginia Valentini

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4599 | Submission Open

Keywords: hereditary cancer; female breast cancer; male breast cancer; molecular oncology; cancer genetics; NGS of gene panels; transcriptomics; genetic predisposition to breast cancer; breast cancer risk; tumor profiling; predictive biomarkers; personalized treatment

(This special issue belongs to the Section Molecular Oncology)

Application of Genetic Engineering in Treatments for Human Diseases

edited by Claudio Mussolino

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4470 | Submission Open

Keywords: genome editing; epigenome editing; CRISPR-Cas systems; gene therapy; precision medicine; molecular mechanisms; innovative therapies; gene expression regulation

(This special issue belongs to the Section Molecular Genetics and Genomics)

Role of Natural Products in Health and Diseases

edited by

Katarína Bauerová

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4388 | Submission Open

Keywords: natural products; health; chronic diseases; biomolecular research; functional food; oncology; rheumatology; infections; inflammation; autoimmunity

(This special issue belongs to the Section Molecular Pharmacology)

Interactions of Microbiome in Skin, Gastrointestinal, and Mucocutaneous Diseases

edited by Capercomorin S. Pitchumoni and

Bijan Safai

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4323 | Submission Open

Keywords: human microbiome; immune system; skin disease; gut– skin axis; gut flora; microbe-host interactions; microbial metabolites; dysbiosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Compounds in Human Brain Structures and Diseases: 2nd Edition

edited by

Terezia Kiskova

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4321 | Submission Open

Keywords: brain; brain cancer; depression; neurodegenerative disorders; natural compounds

(This special issue belongs to the Section Molecular Neurobiology)

Recent Progress in Advanced Computing Techniques for Molecules and Nanomaterials

edited by

Joonho Bae

submission deadline 20 Sep 2025 | 1 articles | Viewed by 4299 | Submission Open

Keywords: nanomaterials; machine learning; artificial intelligence; computing techniques; modeling; energy storage; catalysis

(This special issue belongs to the Section Molecular Nanoscience)

Redox Enzymes: Molecular Mechanisms, Structural Features, Physiological Roles

edited by

Vitaliy Borisov

and

Elena Forte

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4223 | Submission Open

Keywords: metalloenzyme; terminal oxidase; cytochrome; heme; respiratory chain; photosynthesis; enzyme activation and inhibition; ROS scavenging enzyme; reactive oxygen species; ROS defense mechanism; molecular bioenergetics; drug target

(This special issue belongs to the Section Molecular Biophysics)

New Trends in Research on Cerebral Ischemia

edited by Hideaki Imai

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4214 | Submission Open

Keywords: white matter damage; ischemia; axon regeneration; intervention; cell transplantation; exosome therapy; stem cells; myelin integrity; neurological disorders; neural repair; cognitive impairments

(This special issue belongs to the Section Molecular Neurobiology)

Small Molecule Drug Design and Research: 3rd Edition

edited by

Adel Nefzi

submission deadline 20 Sep 2025 | 4 articles | Viewed by 4179 | Submission Open

Keywords: drug design; diversity-oriented synthesis; combinatorial chemistry; computationally guided synthesis; drug-like compounds; computer modeling techniques

(This special issue belongs to the Section Molecular Pharmacology)

Pituitary Tumors: An Update in the Pathogenetic Mechanisms, the Diagnostic Methods and the Therapeutic Approaches

edited by

Dimitrios Kanakis

submission deadline 20 Sep 2025 | 3 articles | Viewed by 4125 | Submission Open

Keywords: pituitary neuroendocrine tumors (PitNETs); pituitary transcription factors; PIT1; TPIT; SF1; GATA3; ERα ; pituicytoma; hypothalamic neurocytoma; hypothalamic gangliocytoma

(This special issue belongs to the Section Molecular Oncology)

Molecular Insights on Drug Discovery, Design, and Treatment

edited by Chih Kang Chiang

submission deadline 20 Sep 2025 | 2 articles | Viewed by 4070 | Submission Open

Keywords: antibacterial drugs; antiviral drugs; antioxidant drugs; anti-inflammatory drugs; antibiotics; anticancer drugs; drug discovery; drug development; drug design; drug delivery; drug carriers; nanoparticles; molecular modeling; molecular mechanisms; crystallography; pharmacokinetics; molecular activity; inhibitors and antagonists

(This special issue belongs to the Section Molecular Pharmacology)

Cytokine Networks in Inflammatory Skin Diseases

edited by

Emanuele Scala

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3997 | Submission Open

Keywords: chronic inflammatory skin diseases; immunopathogenesis; inflammatory pathways; cytokines; molecular targets; psoriasis; atopic dermatitis; hidradenitis suppurativa; urticaria; lichen planus

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Perspectives in Nanomedicine

edited by

Stefano Leporatti

submission deadline 20 Sep 2025 | 1 articles | Viewed by 3777 | Submission Open

Keywords: nanomedicine; drug delivery; nano therapy and diagnostics; micro and nanofluidic tools; hybrid nanoparticles; CAR-T nanotechnologies

(This special issue belongs to the Section Molecular Nanoscience)

Advances in Polymers and Polysaccharides in Delivery Systems

edited by

Stefania Racovita

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3767 | Submission Open

Keywords: polysaccharides; synthetic polymers; drug delivery systems; enzyme drugs; gene delivery; targeted release; controlled drug delivery systems

(This special issue belongs to the Section Molecular Pharmacology)

TRP Channel, 2nd Edition

edited by

Louis Premkumar

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3762 | Submission Open

Keywords: TRP; TRPAnkyrin; TRPCanonical; TRPMelastatin; TRPPolycystin; TRPVanilloid

(This special issue belongs to the Section Molecular Pharmacology)

Wheat Genetics and Genomics: 3rd Edition

edited by

Xiaojun Nie

submission deadline 20 Sep 2025 | 4 articles | Viewed by 3726 | Submission Open

Keywords: wheat; genetics; molecular breeding; genome variation; multiomics

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular and Translational Research of Non-Small Cell Lung Cancer

edited by

Xabier Mielgo Rubio

submission deadline 20 Sep 2025 | 1 articles | Viewed by 3579 | Submission Open

Keywords: non-small cell lung cancer; precision medicine; targeted therapy; resistance mechanisms; immunotherapy; molecular biomarkers

(This special issue belongs to the Section Molecular Oncology)

DNA and mRNA-Based Vaccines Against Infectious Diseases

edited by

Wentao Li

submission deadline 20 Sep 2025 | 1 articles | Viewed by 3568 | Submission Open

Keywords: mRNA vaccines; DNA vaccines; vaccine delivery; infectious disease; animal model

(This special issue belongs to the Section Molecular Immunology)

Recent Analysis and Applications of Comparative and Functional Genomic on Horticultural Plants: 2nd Edition

edited by

Xiaoming Song

submission deadline 20 Sep 2025 | 3 articles | Viewed by 3500 | Submission Open

Keywords: horticultural plants; gene family; comparative genomics; genome evolution; gene function; gene expression; database construction; tool development

(This special issue belongs to the Section Molecular Genetics and Genomics)

Targeted Radioligand Therapy and Immunotherapy for Cancer Treatment

edited by

Jinda Fan

and

Carolina de Aguiar Ferreira

submission deadline 20 Sep 2025 | 1 articles | Viewed by 3483 | Submission Open

Keywords: targeted radioligand therapy; immunotherapy; receptor targeting; tumor-specific antigens; immune checkpoint inhibitors; radiosensitization; tumor microenvironment; combination therapy

(This special issue belongs to the Section Molecular Oncology)

Nutraceuticals for the Maintenance of Brain Health

edited by

Maria Anttonietta Panaro

submission deadline 20 Sep 2025 | 4 articles | Viewed by 3482 | Submission Open

Keywords: vitamin; nutraceutics; brain; neuroinflammation; neurodegeneration; cognitive function

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Role of SARS-CoV-2 in Immunomodulation—Post-Pandemic Reflection on the Role of Viruses in Human Immunology

edited by

Katarzyna A. Lisowska

submission deadline 20 Sep 2025 | 4 articles | Viewed by 3456 | Submission Open

Keywords: SARS-CoV-2; COVID-19; immunomodulation; T cells; B cells; dendritic cells; monocytes; cytokines

(This special issue belongs to the Section Molecular Immunology)

Technical Developments and Recent Applications of Cellular Molecular Imaging

edited by Hanae Sato

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3429 | Submission Open

Keywords: fluorescence imaging; optogenetics; single-molecule imaging; cellular dynamics; real-time imaging; structural and functional imaging; multimodal imaging

(This special issue belongs to the Section Molecular Biology)

The Molecular Basis of Vascular Pathology

edited by

Jolanta Neubauer-Geryk

submission deadline 20 Sep 2025 | 4 articles | Viewed by 3342 | Submission Open

Keywords: vascular pathologies; blood vessels; dysfunction; vascular damage; blood flow; biomarkers; biomolecules; cytokines

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Electrochemotherapy

edited by Jurij Novickij,

Julita Kulbacka

and

Maja Čemažar

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3300 | Submission Open

Keywords: electrochemotherapy; drug delivery; pulsed electric fields; cancer; drug resistance

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Genetic, Epigenetic and Microbiota Molecular Insights for Crop Resilience to Abiotic Stress

edited by

Aliki Kapazoglou

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3293 | Submission Open

Keywords: abiotic stress; tolerance; crop resilience; crop sustainability; environmental conditions; climate change; gene regulation; epigenetic mechanisms; microbiota communities; microbiome

(This special issue belongs to the Section Molecular Plant Sciences)

Chronic Liver Disease: From Pathophysiology to Treatment

edited by

Jong-Won Kim

submission deadline 20 Sep 2025 | 3 articles | Viewed by 3292 | Submission Open

Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); type 2 diabetes (T2D)

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Musculoskeletal Diseases: Inflammation, Degeneration or Mechanical Stress

edited by

Gianluigi Pasta

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3268 | Submission Open

Keywords: musculoskeletal diseases; inflammation; degeneration; mechanical stress; aging

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Advances in Mental Health and Disorders

edited by Eva Christina Schulte

submission deadline 20 Sep 2025 | 3 articles | Viewed by 3245 | Submission Open

Keywords: molecular studies; mental health disorders; model systems; molecular epidemiology; omics TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in English Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate English to Simplified ChinesePRO Never translate English Never translate admin.mdpi.com

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Computational Methods for Studying the Effects of Radiation on Human Beings

edited by

Mario Antonio Bernal

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3236 | Submission Open

Keywords: DNA damage; biophysical models; DNA geometrical models; computational radiobiology; Monte Carlo simulations; ionizing radiation; heavy ions; DNA damage repair

(This special issue belongs to the Section Molecular Biophysics)

Molecular Mechanisms of Oxidative Stress in Kidney Disease

edited by Stefanos Roumeliotis

submission deadline 20 Sep 2025 | 2 articles | Viewed by 3180 | Submission Open

Keywords: chronic kidney disease; end-stage kidney disease; hemodialysis; peritoneal dialysis; oxidative stress; pro-oxidants; inflammation; atherosclerosis; cardiovascular disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1101-1150 on page 23 of 69.

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