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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Inflammasomes

edited by

Roberto Negro

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2574 | Submission Open

Keywords: inflammasome; pyroptosis; innate immunity; cancer; neurodegenerative diseases; microbiota; gasdermin; ninjurin; drug screening; personalized treatments; multi-omics analysis

(This special issue belongs to the Section Molecular Immunology)

Recent Advances in Molecular and Cellular Approaches to Tuberculosis Pathogenesis, Treatment and Prevention

edited by

Selvakumar Subbian

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2572 | Submission Open

Keywords: tuberculosis (TB); animal models of mycobacterium infections; molecular pathogenesis; host-directed therapy (HDT); nanoparticle drug delivery; vaccine development; cellular immunology; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Genetics and Genomics of Aquatic Crustaceans

edited by

Xianhong Meng

, Falin Zhou and Lingbo Ma

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2533 | Submission Open

Keywords: genome sequencing; epigenomics; CRISPR/Cas9 gene editing; transcriptomics; gene expression profiling; genome-wide association studies (GWASs); quantitative trait loci (QTL) mapping; genomic selection; marker-assisted selection (MAS); molecular markers

(This special issue belongs to the Section Molecular Genetics and Genomics)

Advanced Oxidation Processes for the Decontamination of Emerging Contaminants and Disinfection of Pathogenic Microorganisms

edited by

Chengdu Qi

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2507 | Submission Open

Keywords: advanced oxidation processes; emerging contaminants; pathogenic microorganisms; disinfection; hydroxyl radical; sulfate radical; organic radical

(This special issue belongs to the Section Molecular Microbiology)

Environmental Pollutants Exposure and Toxicity

edited by

Tzveta Georgieva

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2479 | Submission Open

Keywords: environmental pollutants exposure assessment; molecular methods; biomarkers; human safety; environmental safety

(This special issue belongs to the Section Molecular Toxicology)

Advances in Genetic and Epigenetic Research in Skin Diseases

edited by

Nikolai Pace

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2465 | Submission Open

Keywords: skin diseases; genodermatoses; psoriasis; atopic dermatitis; hidradenitis; suppurativa; epigenetic regulation; genome-wide association studies (GWAS); next-generation sequencing; translational dermatogenomics; Mendelian randomization; rare disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insight into Natural Nutraceuticals for Cancer Chemoprevention

edited by

Jia-Feng Chang

and

Chih-Hsin Tang

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2444 | Submission Open

Keywords: natural nutraceuticals; cancer; cancer chemoprevention; natural compounds

(This special issue belongs to the Section Molecular Oncology)

Advances in the Synthesis and Study of Novel Bioactive Molecules

edited by

Adriana Georgieva Bakalova

and

Emiliya Demireva Cherneva

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2432 | Submission Open

Keywords: organic compounds; metal complexes; bioactive molecules

(This special issue belongs to the Section Biochemistry)

Hematopoietic Stem Cells: Molecular Insights into Homeostasis, Disease, and Aging

edited by Yoshikazu Matsuoka

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2429 | Submission Open

Keywords: hematopoietic stem cells (HSCs); senescence; hematopoietic homeostasis; epigenetic drift; DNA damage responses; metabolic reprogramming; hematological disorders; inflammation; environmental stress

(This special issue belongs to the Section Molecular Biology)

Recent Advances in Molecular Imaging and Therapy

edited by

Xuyi Yue

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2425 | Submission Open

Keywords: molecular imaging; therapy; clinical translation; precision medicine; radiotheranostics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research on Embryo Developmental Potential: 2nd Edition

edited by

Jan Tesarik

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2399 | Submission Open

Keywords: embryo developmental potential; oocyte quality; sperm quality; non-invasive techniques; molecular biomarkers

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Next Generation Sequencing in Human Diseases

edited by

Manuel Muro

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2397 | Submission Open

Keywords: NGS; single-cell analysis; metagenomics; forensic DNA analysis; precision medicine; genetic diagnostics; transplant monitoring; cell-free DNA; new allele and variant discovery

(This special issue belongs to the Section Molecular Informatics)

Oral Potentially Malignant Disorders and Oral Cancers: From Molecular Pathology to Therapeutic Approaches

edited by

Ana Caruntu

and Nicholas Kalavrezos

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2337 | Submission Open

Keywords: oral cancer; oral potentially malignant disorders; molecular mechanisms in oral cancer; detection of oral cancer; pathogenic mechanisms of oral cancer; immune system; translational oral cancer; microbiota oral cancer; therapy for oral cancer

(This special issue belongs to the Section Molecular Oncology)

Breakthroughs in Anti-Cancer Agents Discovery

edited by

Giulia Bononi

submission deadline 20 Aug 2026 | 3 articles | Viewed by 2335 | Submission Open

Keywords: medicinal chemistry; drug discovery; cancer; anti-cancer agents; synthesis; bioactive molecules; biological evaluation; computational drug discovery; artificial intelligence

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in Medicinal Plants and Natural Products: Second Edition

edited by

Teresa Leszczyńska

Barbara Borczak

and

Joanna Kapusta-Duch

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2267 | Submission Open

Keywords: medicinal plants; natural products; phytochemistry; bioactive substances; medicinal properties

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Upcycling Food Industry By-Products: Bioactive Ingredients for Nutrition and Health

edited by

Giusy Rita Caponio

and

Graziana Difonzo

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2256 | Submission Open

Keywords: bioactive compounds; food by-products; functional foods; molecular mechanisms; polyphenols; oxidative stress; inflammation; nutrigenomics; microbiome; prebiotics; postbiotics

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Recent Advances in Regenerative and Anti-Aging Medicine

edited by

Takayuki Yoshimoto

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2215 | Submission Open

Keywords: induced pluripotent stem cells (iPSCs); mesenchymal stem cells (MSCs); platelet-rich plasma (PRP); placenta; organoid; secretome; exosome; senolytics; nicotinamide mononucleotide (NMN); nicotinamide adenine dinucleotide+ (NAD+)

(This special issue belongs to the Section Molecular Biology)

Molecular Studies on Wnt Signaling

edited by Katalin Mészáros

submission deadline 20 Aug 2026 | 2 articles | Viewed by 2168 | Submission Open

Keywords: Wnt signaling pathway; inhibitor; cancer; treatment; drugs

(This special issue belongs to the Section Molecular Biology)

The Role of Extracellular Histones in Patho(physio)logical Hemostasis

edited by Fabrizio Semeraro and

Mauro Coluccia

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2125 | Submission Open

Keywords: extracellular histones; hemostasis; platelets; coagulation; fibrinolysis; thrombosis; inflammation; extracellular traps

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Targets on Anticancer Research and Perspectives

edited by

Apostolos E. Papalois

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2099 | Submission Open

Keywords: anticancer; molecular targets; targeted cancer therapies; malignancy

(This special issue belongs to the Section Molecular Oncology)

The Role of Ion Channels in Health and Disease

edited by

Joohyun Nam

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2068 | Submission Open

Keywords: ion channel; molecular mechanisms; channelopathies; drug discovery; electrophysiology

(This special issue belongs to the Section Molecular Biology)

New Advances in Amyotrophic Lateral Sclerosis

edited by

Vacchiano Veria

submission deadline 20 Aug 2026 | 1 articles | Viewed by 2049 | Submission Open

Keywords: genetics and epigenetics; biomarkers; nutrition and metabolism; TDP-43 pathology; advanced model of ALS

(This special issue belongs to the Section Molecular Neurobiology)

Systemic Lupus: Molecular Research, New Biomarkers and Novel Therapy

edited by Juan Pablo Mackern-Oberti

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1984 | Submission Open

Keywords: lupus; biomarkers; autoimmunity; inflammation; therapy; treatment; endocrine; prolactin; stress; T cell and B cell activation; T cell and B cell proliferation; antigenic immunosuppression

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

From Synapse to Substance Use: Endocannabinoids and Cannabinoid Receptors in Brain Plasticity and Addiction Circuits

edited by Balapal S. Basavarajappa

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1982 | Submission Open

Keywords: anandamide; cannabis; alcohol; drug abuse; plasticity; neurotransmitters; cell-types; reward system

(This special issue belongs to the Section Molecular Neurobiology)

Recent Research on Gut Microbiota in Health and Disease

edited by Li Cui

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1977 | Submission Open

Keywords: microbiota-host crosstalk; HMA models; microbial metabolites; gut– brain axis; translational microbiome

(This special issue belongs to the Section Molecular Microbiology)

Molecular Mechanisms of Toxicity Induced by Engineered Nanomaterials

edited by

Shan Zienolddiny-Narui

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1946 | Submission Open

Keywords: toxicity; occupational health; engineered nanomaterials; physical– chemical characteristics; toxicokinetic; toxicodynamic; in vivo; NAMs; NGRA (new-generation risk assessment)

(This special issue belongs to the Section Molecular Toxicology)

Synthesis and Structural Studies of Potential Anticancer Drugs

edited by Janusz Madaj

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1945 | Submission Open

Keywords: medicinal chemistry; drug discovery; design and synthesis of bioactive compounds; molecular modeling; X-ray crystallography; structure– activity relationships; structure-based drug design

(This special issue belongs to the Section Molecular Pharmacology)

Unraveling Synaptic Structure and Function in the Healthy and Diseased Brain

edited by

Jacopo Meldolesi

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1923 | Submission Open

Keywords: molecular studies; axons; synapses; diseases; glial cells

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Epilepsy: Exploring the Molecular Mechanisms and Potential Medications

edited by

Motohiro Okada

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1810 | Submission Open

Keywords: idiopathic epilepsy; genetic epilepsy; transmission; development; signaling; synaptic plasticity; pathophysiology; modulation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Acute Myeloid Leukemia: From Molecular Insights to Therapeutic Innovations

edited by

Lukasz Szymanski

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1798 | Submission Open

Keywords: acute myeloid leukemia; AML; epigenetic Mechanisms; genetics; epigenetic regulation

(This special issue belongs to the Section Molecular Genetics and Genomics)

Macrophage Metabolic Reprogramming in Inflammation

edited by

Ricardo Sánchez-Rodríguez

and

Roberta Angioni

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1771 | Submission Open

Keywords: inflammation; immunometabolism; metabolic rewiring; glycolysis; krebs cycle; glutaminolysis; innate immune response; macrophages

(This special issue belongs to the Section Molecular Immunology)

Significance and Challenges of Plant-Derived Natural Compounds in Cancers

edited by Ba Vinh Le

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1769 | Submission Open

Keywords: metabolomic; bioactive compound; pharmacognosy; oriental medicine; drug discovery; pharmacology; anti-cancer; pharmacological effects

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in Fluorescent Sensors

edited by

Levente Cseri

and

Ervin Kovács

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1751 | Submission Open

Keywords: fluorescence probe; fluorescent nanomaterials; analyte recognition; fluorescence imaging; real-time monitoring; photoinduced electron transfer; Fö rster resonance energy transfer; genetically encoded indicators; sensor devices; fluorescence microscopy

(This special issue belongs to the Section Materials Science)

Biomaterials and Antibacterial Materials for Medical Applications

edited by

Shixiong Yi

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1743 | Submission Open

Keywords: biomaterial science; photodynamic antibacterial materials; photothermal antibacterial materials; advanced antibacterial materials; antimicrobial nanostructured materials; polymer-based biomaterials; infected wound dressings

(This special issue belongs to the Section Materials Science)

Molecular Advances and Views in Triple-Negative Breast Cancer

edited by

Ioannis Boutas

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1730 | Submission Open

Keywords: breast cancer; molecular biology; personalized medicine; triple-negative breast cancer

(This special issue belongs to the Section Molecular Oncology)

Bioactive Peptides: Discovery, Synthesis, and Therapeutic Applications

edited by

Chuan-Mu Chen

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1707 | Submission Open

Keywords: bioactive peptides; functional food-derived peptides; antimicrobial and antiviral peptides; peptide drug design and delivery; anticancer peptides; peptide-based therapeutics; regenerative medicine; immunomodulatory peptides; structure– function relationships; translational peptide research

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Cellular and Molecular Mechanisms of Central Nervous System Injury

edited by

Laurent R. Gauthier

and

José R. Pineda

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1703 | Submission Open

Keywords: central nervous system damage; CNS; oxidative stress; DNA damage responses; neuroregeneration; blood– brain barrier disruption

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights in Food Science: From Nutritional Value to Safety Evaluation

edited by

Mariachiara Bianco

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1701 | Submission Open

Keywords: nutraceutical; food safety; analytical methods; novel foods; food analysis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Aspects of Diabetes and Its Complications

edited by

Giuseppe Murdolo

submission deadline 20 Aug 2026 | 3 articles | Viewed by 1683 | Submission Open

Keywords: obesity; insulin resistance; type 2 diabetes; atherosclerosis; endothelial dysfunction; cardiovascular disease; peripheral artery disease; diabetic feet; diabetic micoangiopathy; diabetic neuropathy; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Biopolymer-Based Materials: Synthesis, Characterization and Applications for a Sustainable Future

edited by

Agnieszka Feliczak-Guzik

and

Agata Wawrzyńczak

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1680 | Submission Open

Keywords: biodegradable polymers; biopolymers; biopolymer-based composite materials; synthesis and characterization of biopolymer materials; applications of biopolymers and biopolymer-based composites

(This special issue belongs to the Section Materials Science)

Targeting Epilepsy: Molecular Mechanisms, Neuroinflammation and Emerging Therapies

edited by

Karoly Orban-Kis

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1664 | Submission Open

Keywords: epilepsy; molecular targets; antiepileptic drug discovery; neuroinflammation; epileptogenesis; ion channels; pharmacoresistance; translational neuroscience

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Developing Methods and Molecular Basis in Plant Biotechnology: 2nd Edition

edited by

Wojciech Makowski

submission deadline 20 Aug 2026 | 3 articles | Viewed by 1625 | Submission Open

Keywords: plant biotechnology; plant genetics; plant proteomics; plant metabolomics; stress

(This special issue belongs to the Section Molecular Plant Sciences)

Advanced Strategies in Bacterial Antibiotic Resistance

edited by Xuemei Yang

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1608 | Submission Open

Keywords: antibiotic resistance; resistance mechanisms; antibiotic resistance genes (ARGs); antibiotic tolerance; heteroresistance; horizontal gene transfer (HGT); compensatory evolution

(This special issue belongs to the Section Molecular Microbiology)

Novel Insights into Mitochondrial Signaling and Homeostasis in Metabolic Diseases

edited by Ching-Yi Chen

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1581 | Submission Open

Keywords: diabetes mellitus; cardiovascular disease; fatty liver; chronic kidney disease; mitochondrial homeostasis

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Brain Ischemia: From Molecular Mechanisms to Innovative Therapies

edited by

Ryszard Pluta

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1580 | Submission Open

Keywords: ischemic neurodegeneration; focal brain ischemia; global brain ischemia; perinatal asphyxia; ischemic stroke; traumatic brain injury; apnea; neuroinflammation; proteins; genes; genes involved in neurodegeneration; glia-to-neurons genetic conversion; dementia; Alzheimer’s disease; genetic conversion of ischemia to Alzheimer's disease; new therapeutic approaches; biomarkers

(This special issue belongs to the Section Molecular Biology)

Advances in Stem Cell Biology and Translational Medicine

edited by Yangluowa Qu

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1579 | Submission Open

Keywords: stem cell regulation; differentiation; proliferation; self-renewal; stem cell-based therapy; tissue engineering; translational research

(This special issue belongs to the Section Molecular Biology)

Molecular Insights into Microglia in Neurological Diseases

edited by

Pyung-Hwan Kim

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1578 | Submission Open

Keywords: microglia; neuroinflammation; neurodegenerative diseases; molecular signaling; central nervous system (CNS)

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms of Toxicity Caused by Environmental Pollutants

edited by Ivan Girón-Perez

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1543 | Submission Open

Keywords: environmental pollutant; molecular toxicity; immunotoxicology; neurotoxicity

(This special issue belongs to the Section Molecular Toxicology)

Natural Compounds in Neurological Diseases

edited by

Ivan Cruz-Chamorro

submission deadline 20 Aug 2026 | 1 articles | Viewed by 1543 | Submission Open

Keywords: natural compounds; neuroprotection; neuroinflammation; oxidative stress; mitochondrial dysfunction; autophagy; bioactive molecules (polyphenols; flavonoids; melatonin; etc.); nutraceuticals (bioactive peptides; hydrolysates; etc.); neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Kidney Disease: Molecular Insights and Emerging Therapies

edited by

Yaochun Zhang

submission deadline 20 Aug 2026 | 2 articles | Viewed by 1540 | Submission Open

Keywords: kidney disease; molecular mechanism; precision medicine; translational nephrology; targeted molecular therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 1101-1150 on page 23 of 65.

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