Natural Compounds in Neurological Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 537
Special Issue Editor
Interests: functional foods; protein hydrolysate; antioxidant; immunomodulation; natural extracts; biopeptides; lupine; hemp
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Neurological diseases, including neurodegenerative and neuroinflammatory disorders, represent a major global health challenge. Emerging evidence has highlighted the neuroprotective potential of natural compounds, which act through diverse molecular mechanisms, such as oxidative stress modulation, neuroinflammation regulation, mitochondrial function preservation, and autophagy enhancement. Bioactive molecules derived from plants, fungi, and marine organisms—such as polyphenols, flavonoids, terpenoids, and alkaloids—have shown promising effects in both preclinical and clinical studies.
This Special Issue will investigate the molecular mechanisms by which natural compounds influence neuronal survival, immune responses, and cellular signaling pathways in neurological disorders. We welcome original research and review articles exploring novel bioactive molecules, their molecular targets, and their potential therapeutic applications in neurodegenerative diseases, neuroinflammation, and related conditions.
This Special Issue is led by Prof. Dr. Ivan Cruz-Chamorro and assisted by our GE's Assistant Editor, Dr. Ana Isabel Álvarez-López (<aialvarez-ibis@us.es>, Departamento de Bioquímica Médica y Biología Molecular e Inmunología, Facultad de Medicina, Universidad de Sevilla, 41009 Seville, Spain).
Dr. Ivan Cruz-Chamorro
Guest Editor
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Keywords
- natural compounds
- neuroprotection
- neuroinflammation
- oxidative stress
- mitochondrial dysfunction
- autophagy
- bioactive molecules (polyphenols, flavonoids, melatonin, etc.)
- nutraceuticals (bioactive peptides, hydrolysates, etc.)
- neurodegenerative diseases
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