New Advances in Amyotrophic Lateral Sclerosis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 379
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue will cover varied topics within the field of molecular research on amyotrophic lateral sclerosis (ALS), including but not limited to the following:
- Genetic mutations and their role in familial and sporadic ALS;
- Epigenetic modifications and their impact on gene expression in ALS;
- Protein misfolding and aggregation, particularly TDP-43 pathology;
- Mitochondrial dysfunction, oxidative stress, and altered energy metabolism in ALS;
- Neuroinflammation and its molecular mediators;
- Nutritional status, metabolic changes, and their influence on disease progression and patient outcomes;
- Advances in biomarker discovery for the early diagnosis and monitoring of ALS;
- Novel and advanced models for ALS, such as animal models, organoids, induced pluripotent stem cells (iPSCs), and three-dimensional (3D) culture systems.
Dr. Vacchiano Veria
Guest Editor
Manuscript Submission Information
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Keywords
- genetics and epigenetics
- biomarkers
- nutrition and metabolism
- TDP-43 pathology
- advanced model of ALS
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