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Advances in Stem Cell Biology and Translational Medicine

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 38

Special Issue Editor


E-Mail Website
Guest Editor
Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA
Interests: corneal stem cells; corneal tissue engineering; ocular surface disease

Special Issue Information

Dear Colleagues,

Stem cells are central to the development, maintenance, and regeneration of tissues across a broad range of biological systems. Their remarkable potential for self-renewal and differentiation makes them powerful tools in both basic science and translational medicine. Dysfunction or depletion of stem cells is implicated in a variety of diseases. In recent years, stem cell-based therapies have emerged as promising strategies for tissue repair and functional restoration. However, significant challenges remain, including a need for a deeper understanding of stem cell biology and optimized protocols for clinical translation.

This Special Issue aims to highlight recent advances in stem cell research, including basic mechanistic studies, translational models, and clinical applications. We welcome original research articles, comprehensive reviews, and methods. Topics of interest include, but are not limited to, the following:

  • Mechanisms regulating stem cell proliferation, differentiation, and self-renewal;
  • Identification of novel biomarkers and lineage tracing of stem and progenitor cells;
  • Stem cell-based therapies and their underlying mechanisms;
  • Advances in biomaterial scaffolds for stem cell-based tissue engineering;
  • Optimization of cell differentiation protocols and cell culture systems for clinical translation;
  • Immunological responses and strategies for immune modulation in stem cell therapies.

Dr. Yangluowa Qu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • stem cell regulation
  • differentiation
  • proliferation
  • self-renewal
  • stem cell-based therapy
  • tissue engineering
  • translational research

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Published Papers

This special issue is now open for submission.
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