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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research in Asthma and Allergy
edited by
submission deadline 20 Aug 2026 | 6 articles | Viewed by 13340 | Submission Open
Keywords: asthma; allergy; molecular mechanisms; exposome; treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant–Microbe Interactions: 2nd Edition
edited by Jian Jin
submission deadline 20 Aug 2026 | 6 articles | Viewed by 13194 | Submission Open
Keywords: plant; crop; rhizosphere microbiome; microbial colonization; quorum sensing; endophytic microbes
(This special issue belongs to the Section Molecular Plant Sciences)
25th Anniversary of IJMS: Updates and Advances in “Molecular Immunology”
edited by
submission deadline 20 Aug 2026 | 6 articles | Viewed by 13074 | Submission Open
Keywords: inflammation; innate immunity; adaptive immunity; genetics; epigenetics; immunometabolism; receptors; cytokines; cell therapy; immune checkpoint inhibitors
(This special issue belongs to the Section Molecular Immunology)
Anti-Cancer Drugs: Natural Products, Synthetic Compounds and Potential Pharmacological Effects and Applications
edited by Kaiqun Ren and Hui Zou
submission deadline 20 Aug 2026 | 4 articles | Viewed by 12551 | Submission Open
Keywords: cancer; natural product; synthetic compounds; mechanism; structural modification; pharmacological action
(This special issue belongs to the Section Molecular Pharmacology)
Studies on Lactic Acid Bacteria and Their Products in Health and Diseases: 3rd Edition submission deadline 20 Aug 2026 | 7 articles | Viewed by 12263 | Submission Open
Keywords: lactic acid bacteria; probiotics health benefits; gut microbiota modulation; functional foods with biological applications; immunomodulatory mechanisms; antimicrobial peptide production and its mechanisms; host-microbe interactions; functional dairy and meat products; inflammatory bowel diseases; metabolic health improvement; bioactive microbial metabolites; food safety and management; metabolic diseases and disorders; antibiotic-associated complications
(This special issue belongs to the Section Bioactives and Nutraceuticals)
The Role of Cytokines and Autoantibodies Against Cytokines in Health and Disease submission deadline 20 Aug 2026 | 1 articles | Viewed by 11889 | Submission Open
Keywords: cytokine; autoantibodies; cytokine therapy; cytokine inhibition
(This special issue belongs to the Section Molecular Immunology)
Molecular and Cellular Mechanisms of Skin Diseases (Second Edition)
edited by
submission deadline 20 Aug 2026 | 5 articles | Viewed by 11082 | Submission Open
Keywords: hyperproliferative skin diseases; psoriasis; keratinocyte carcinoma; actinic keratosis; atopic dermatitis; skin inflammation; inflammation-associated skin diseases; epidermal differentiation; epidermal cell metabolism; 3D models; in vivo models
(This special issue belongs to the Section Molecular Biology)
New Advances in Cancer Genomics
edited by
submission deadline 20 Aug 2026 | 7 articles | Viewed by 11035 | Submission Open
Keywords: cancer genomics; biomarker discovery; precision oncology; KRAS and undruggable targets; artificial intelligence in oncology; multi-omics data integration; drug discovery
(This special issue belongs to the Section Molecular Biology)
New Insights into Plant Stress submission deadline 20 Aug 2026 | 4 articles | Viewed by 10819 | Submission Open
Keywords: abiotic stress; biotic stress; bioinformatics; artificial intelligence; biotechnology; breeding; crop plants; horticultural plants; GWAS; CRISPR-Cas; multi-omics; genomics; epigenomics; transcriptomics; proteomics; genetic diversity; gene expression
(This special issue belongs to the Section Molecular Plant Sciences)
Circulating Non-Coding RNAs as Diagnostic and Prognostic Markers of Human Diseases: 3rd Edition submission deadline 20 Aug 2026 | 7 articles | Viewed by 10689 | Submission Open
Keywords: miRNA; gene expression regulation; diagnosis; prognosis; therapy; biomarkers
(This special issue belongs to the Section Biochemistry)
Chronic Kidney Disease: From Molecular Mechanisms to Therapeutic Approaches
edited by
submission deadline 20 Aug 2026 | 6 articles | Viewed by 10625 | Submission Open
Keywords: genetics; epigenetics; inflammation; metabolomics; oxiative stress
(This special issue belongs to the Section Molecular Biology)
Plant Molecular Regulatory Networks and Stress Responses
edited by
submission deadline 20 Aug 2026 | 5 articles | Viewed by 10598 | Submission Open
Keywords: plant stress response; stress response gene; regulatory mechanism; gene regulatory network; transcriptional regulation; post-transcriptional regulation; multi-omics integration; single-cell RNA-seq; spatial genomics; bioinformatics
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Research on Depression—2nd Edition submission deadline 20 Aug 2026 | 2 articles | Viewed by 9954 | Submission Open
Keywords: depression; epigenetics; animal models of depression; serotonin; glutamate; dopamine; neurotrophic factors
(This special issue belongs to the Section Molecular Neurobiology)
Challenges and Future Perspectives in Treatment for Lung Cancer: 2nd Edition
edited by Ilaria Marrocco and
submission deadline 20 Aug 2026 | 2 articles | Viewed by 9944 | Submission Open
Keywords: lung cancer; non-small cell lung cancer; small cell lung cancer; chemotherapy; targeted therapy; immunotherapy; drug resistance; drug delivery
(This special issue belongs to the Section Molecular Oncology)
Advances in Antimicrobial Nanomaterials 2.0
edited by
submission deadline 20 Aug 2026 | 4 articles | Viewed by 9629 | Submission Open
Keywords: metallic nanoparticles; bimetallic nanoparticles; antimicrobial activity; polymeric nanomaterials; nanoplatforms; nanoparticle functionalization; delivery of antimicrobial agents
(This special issue belongs to the Section Molecular Nanoscience)
Biochemistry and Molecular Biology of Coronaviruses
edited by
submission deadline 20 Aug 2026 | 6 articles | Viewed by 9523 | Submission Open
Keywords: SARS-CoV; MERS-CoV; COVID-19; RNA viruses; infection; antivirals; vaccines; therapeutics; host-virus interactions
(This special issue belongs to the Section Molecular Microbiology)
25th Anniversary of IJMS: Updates and Advances in Molecular Informatics submission deadline 20 Aug 2026 | 10 articles | Viewed by 9463 | Submission Open
Keywords: AI-guided drug repurposing; virtual screening in personalized medicine; machine learning for toxicity prediction; network-based biomarkers in complex diseases; in silico pharmacokinetics and ADMET profiling; data-driven materials design; deep learning for molecular property prediction; AI-assisted nanomaterial synthesis; systems biology models for metabolic engineering
(This special issue belongs to the Section Molecular Informatics)
MicroRNAs and mRNA in Human Health and Disease
edited by
submission deadline 20 Aug 2026 | 7 articles | Viewed by 9371 | Submission Open
Keywords: stem cells; mesenchymal stem cells; gene expression; microRNA; mRNA
(This special issue belongs to the Section Molecular Biology)
Advances in Amyloid Aggregation and Its Inhibition: Implementing Insights from Physiological Conditions submission deadline 20 Aug 2026 | 4 articles | Viewed by 9359 | Submission Open
Keywords: protein aggregation; amyloid; physiological conditions; aggregation inhibition; neurodegenerative diseases; amyloidosis
(This special issue belongs to the Section Molecular Neurobiology)
Toxicity Mechanism of Emerging Pollutants: 2nd Edition submission deadline 20 Aug 2026 | 6 articles | Viewed by 9001 | Submission Open
Keywords: emerging pollutant; toxicology; cancer; EDC; pesticides; microplastic; human cell lines; environment; molecular mechanisms
(This special issue belongs to the Section Molecular Toxicology)
Molecular Insights into Antimicrobial Activity submission deadline 20 Aug 2026 | 2 articles | Viewed by 8558 | Submission Open
Keywords: antimicrobial activity; antimicrobial agents; antimicrobial peptides; phytochemicals with antimicrobial properties; antimicrobial synergy; pathogen-specific targeting; antimicrobial resistance; biomedical science; nanotechnology in antimicrobials; genomic
(This special issue belongs to the Section Molecular Microbiology)
Rapeseed: Genetic Breeding, Key Trait Mining and Genome
edited by Hongbo Chao
submission deadline 20 Aug 2026 | 4 articles | Viewed by 8102 | Submission Open
Keywords: rapeseed (Brassica napus L.); genetic breeding; genomic improvement; molecular markers; genome-wide association studies (GWAS); multi-omics integration; CRISPR gene editing; marker-assisted selection (MAS); stress resistance traits; yield and oil content improvement
(This special issue belongs to the Section Molecular Plant Sciences)
Recent Advances in Brain Cancers: Second Edition submission deadline 20 Aug 2026 | 1 articles | Viewed by 7700 | Submission Open
Keywords: brain tumors; malignant brain tumor; advanced cancer biology
(This special issue belongs to the Section Molecular Oncology)
Biomarkers in Precision Medicine
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 7694 | Submission Open
Keywords: biomarkers; precision medicine; novel techniques; artificial intelligence
(This special issue belongs to the Section Molecular Biology)
Antimicrobial Nanomaterials: Approaches, Strategies and Applications
edited by
submission deadline 20 Aug 2026 | 3 articles | Viewed by 7653 | Submission Open
Keywords: nanotechnology; biocides; antimicrobials; controlled release; drug delivery; antimicrobial agents; antimicrobial resistance; infection; nanoparticles
(This special issue belongs to the Section Materials Science)
Molecular Mechanisms of Neutrophil Extracellular Traps (Nets) in Human Diseases
edited by Eisuke F. Sato
submission deadline 20 Aug 2026 | 3 articles | Viewed by 7651 | Submission Open
Keywords: neutrophil extracellular traps (NETs); neutrophils; inflammation; autoimmune diseases; cardiovascular diseases; tumor metastasis; thrombosis; molecular mechanisms; disease progression; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Stress Biology
edited by Rui Li
submission deadline 20 Aug 2026 | 7 articles | Viewed by 7568 | Submission Open
Keywords: abiotic stress; biotic stress; stress response mechanisms; oxidative stress; phytohormones signaling; stress tolerance
(This special issue belongs to the Section Molecular Plant Sciences)
25th Anniversary of IJMS: Updates and Advances in Molecular Plant Sciences
edited by
submission deadline 20 Aug 2026 | 8 articles | Viewed by 7376 | Submission Open
Keywords: plant science; plant biochemistry; mechanisms; plant development; stress responses; plant physiology; genetics
(This special issue belongs to the Section Molecular Plant Sciences)
Advances in Seed Development and Germination submission deadline 20 Aug 2026 | 4 articles | Viewed by 7314 | Submission Open
Keywords: seed aging; seed development; seed dormancy; seed germination; seed metabolism; seed preservation; seed priming; seed responses to stress
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Imaging for Cancer Theranostics
edited by and Kai Bao
submission deadline 20 Aug 2026 | 2 articles | Viewed by 7279 | Submission Open
Keywords: molecular imaging; cancer theranostics; precision medicine; targeted therapy; diagnostic imaging; theranostic agents; multimodal imaging; molecular probes
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Urologic Cancers: Molecular Basis for Novel Therapeutic Approaches
edited by
submission deadline 20 Aug 2026 | 5 articles | Viewed by 7217 | Submission Open
Keywords: urologic cancers; prostate cancer; urothelial cancer; renal cell cancer; genomics; proteomics; biomarkers; molecular pathways
(This special issue belongs to the Section Molecular Oncology)
Oxidative and Redox Signalling in Neurological Diseases
edited by
submission deadline 20 Aug 2026 | 3 articles | Viewed by 7205 | Submission Open
Keywords: gasotransmitters; neurological diseases; oxidative stress; redox signalling; reactive oxygen species (ROS); neuroinflammation; mitochondrial dysfunction; cell death/apoptosis; nitrosative stress; endogenous gas signalling; neuromodulation; neurovascular coupling; therapeutic strategies; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Extracellular Vesicles (EVs) in Cancer Progression and Metastasis: Molecular Insights and Clinical Outlook
edited by Alfredo Cappariello
submission deadline 20 Aug 2026 | 3 articles | Viewed by 7123 | Submission Open
Keywords: mammalian extracellular vesicles; plant-derived extracellular vesicles; bacterial-derived extracellular vesicles; cancer progression; cell migration and invasion; tumor microenvironment; epithelial-to-mesenchymal transition (EMT); drug delivery; diagnostics; precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Post-Mortem Toxicology
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 6855 | Submission Open
Keywords: post-mortem toxicology; fatal poisoning; new psychoactive substances; opioids; analytical methods; interpretation of test results
(This special issue belongs to the Section Molecular Toxicology)
New Insights into the Mechanisms of Neurodegeneration and Regeneration: From Bench to Bedside
edited by Irina Ivanova Stoyanova
submission deadline 20 Aug 2026 | 4 articles | Viewed by 6559 | Submission Open
Keywords: neurodegeneration; neuroregeneration; molecular neurobiology; brain development; developmental brain disorders; synaptogenesis; synaptic plasticity; cognitive neuroscience; neurotrauma
(This special issue belongs to the Section Molecular Neurobiology)
Nutraceuticals and Healthy Aging: Molecular Mechanisms and Therapeutic Perspectives
edited by
submission deadline 20 Aug 2026 | 4 articles | Viewed by 6482 | Submission Open
Keywords: molecular mechanisms of the action of nutraceuticals on cellular aging; nutraceuticals and neuroprotection; effects of nutraceuticals on skin aging; nutraceuticals in the prevention or management of age-related metabolic diseases; interaction between nutraceuticals and gut microbiota in aging; nutraceuticals in bone and joint health; role of nutraceuticals in menopausal management; impact of nutraceuticals on BPH and prostate health; multi-target approaches of nutraceuticals in healthy aging; innovative nutraceutical delivery and formulation strategies to increase bioavailability; clinical and preclinical studies of nutraceuticals in the elderly population
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Functional Genomics in Translational Medicine
edited by , Oana Zanoaga and
submission deadline 20 Aug 2026 | 2 articles | Viewed by 6395 | Submission Open
Keywords: functional genomics; omics approaches; drug response/resistance; therapeutic targets; genomics and transcriptomic alteration; bioinformatic analysis; data integration; human disease; personalized medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
Innovative Strategies in the Design and Development of Anticancer Agents
edited by Sanjay Kumar
submission deadline 20 Aug 2026 | 4 articles | Viewed by 5938 | Submission Open
Keywords: chemotherapy; biomimetic; natural product analogs; prodrugs; nanodrugs; drug release
(This special issue belongs to the Section Molecular Pharmacology)
Zebrafish: A Model Organism for Human Health and Disease: 2nd Edition
edited by
submission deadline 20 Aug 2026 | 4 articles | Viewed by 5936 | Submission Open
Keywords: zebrafish; drug discovery; high-throughput screens; genome editing/CRISPR mutants; cancer; neuronal disorders; drug toxicity; drug effect mechanisms; developmental disorders
(This special issue belongs to the Section Molecular Biology)
Fish Nutrition, Biochemical Pathways, and Physiological Adaptations
edited by Paula Simó-Mirabet and Fernando Naya-Català
submission deadline 20 Aug 2026 | 2 articles | Viewed by 5916 | Submission Open
Keywords: fish; nutrition; metabolism; physiology; growth performance; fish stress; transcriptomics; metataxonomics; metagenomics; epigenomics; aquaculture
(This special issue belongs to the Section Molecular Biology)
Obesity: From Cellular Mechanism to Potential Molecular Therapies
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 5607 | Submission Open
Keywords: metabolic pathways; gene expression; epigenetics; obesity-related comorbidities; molecular biomarkers; adipogenesis; therapeutic interventions; small molecules; gene therapy/gene editing; obesity and cancer
(This special issue belongs to the Section Molecular Biology)
Neurodegenerative Diseases: Genetic Bases and Pathogenetic Mechanisms
edited by Emanuele Panza
submission deadline 20 Aug 2026 | 3 articles | Viewed by 5520 | Submission Open
Keywords: neurodegenerative diseases; molecular and cellular pathways; pathogenetic mechanisms
(This special issue belongs to the Section Molecular Neurobiology)
Fungal Genetics and Functional Genomics Research
edited by and
submission deadline 20 Aug 2026 | 6 articles | Viewed by 4708 | Submission Open
Keywords: enzymes; fungal genetics; fungi; gene editing; regulation; secondary metabolites; synthetic biology; transcription
(This special issue belongs to the Section Molecular Genetics and Genomics)
Ion Channels as Therapeutic Target: Drug Design and Pharmacological Investigation (3rd Edition)
edited by
submission deadline 20 Aug 2026 | 5 articles | Viewed by 4619 | Submission Open
Keywords: LGIC; voltage-gated ion channel; other ion channels; biological studies; molecular modeling; drug design; synthesis
(This special issue belongs to the Section Molecular Pharmacology)
Intestinal Diseases and Gut Microbiota
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 4619 | Submission Open
Keywords: gut microbiota; dysbiosis; natural compounds; colorectal cancer; neurological diseases; autoimmune diseases; probiotics; gut-brain axis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Progress in Adipokines Research in Cardiovascular Health and Diseases
edited by
submission deadline 20 Aug 2026 | 4 articles | Viewed by 4617 | Submission Open
Keywords: adipokine receptors and cell signalling; adipokines and heart failure and hypertrophy; adipokines and myocardial ischemia; adipokines and hypertension; adipokines and thrombosis/atherosclerosis; adipokines and vascular/endothelial function; structure; and integrity; adipokines and cardiovascular inflammation; adipokines; adiposity; and cardiovascular disease in obesity
(This special issue belongs to the Section Molecular Biology)
Hearing Loss: Molecular Biological Insights, 2nd Edition
edited by María Beatriz Durán-Alonso
submission deadline 20 Aug 2026 | 4 articles | Viewed by 4115 | Submission Open
Keywords: genetics; microRNA; epigenetics; CRISPR; multi-omics; presbycusis; ototoxicity; development
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
From Electronic Structure to Application: Computational Insights into Bioactive and Functional Molecules
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 4016 | Submission Open
Keywords: molecular design; molecular modeling; substituent effect; reactivity descriptors; biological potential; in silico study; physicochemical properties; ADME; PASS; QSAR
(This special issue belongs to the Section Molecular Informatics)
Advanced Research of Plant-Pathogen Interaction
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 3989 | Submission Open
Keywords: molecular plant-pathogen interactions; pathogen detection; secondary metabolism; multi-omics approaches; antibiotic resistance
(This special issue belongs to the Section Molecular Plant Sciences)
The Application of an Electron Microscope in the Study of Cell Structure
edited by
submission deadline 20 Aug 2026 | 5 articles | Viewed by 3985 | Submission Open
Keywords: intracellular structure; organelles; cell surface structure; immuno-labeling
(This special issue belongs to the Section Molecular Biophysics)
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