Systemic Lupus: Molecular Research, New Biomarkers and Novel Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 42
Special Issue Editor
Interests: systemic lupus erythematosus; autoimmunity; therapy; treatment; biomarker
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with highly variable clinical manifestations and an elusive pathogenesis. Despite advances in immunology and genetics, effective and targeted treatments remain a challenge. This Special Issue invites cutting-edge research that deepens our understanding of SLE at the molecular level, with a strong focus on identifying innovative biomarkers, endocrine regulation of T cell and B cell activation, and emerging therapeutic strategies. We aim to highlight interdisciplinary efforts that bridge laboratory findings, basic research with clinical application, including studies on epigenetics, cellular signaling pathways, immune profiling, and novel drug targets. Submissions exploring translational research and precision medicine are especially encouraged. By fostering collaboration among basic scientists, clinicians, and biopharmaceutical researchers, this Special Issue seeks to accelerate progress toward more effective and personalized approaches to lupus care. Authors are encouraged to contribute original research, reviews, or perspective articles that can shape the future landscape of SLE diagnostics and treatment.
Dr. Juan Pablo Mackern-Oberti
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- lupus
- biomarkers
- autoimmunity
- inflammation
- therapy
- treatment
- endocrine
- prolactin
- stress
- T cell and B cell activation
- T cell and B cell proliferation
- antigenic immunosuppression
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