Molecular Aspects of Diabetes and Its Complications
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 25
Special Issue Editor
Interests: obesity; insulin resistance; adipose tissue; diabetes mellitus, peripheral artery disease; diabetic foot
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The management of diabetes remains a major global health challenge. Despite advances in treatment, diabetes accounts for approximately 6% of total global mortality, with many of these deaths attributable to cardiovascular disease. In addition, diabetes is the leading cause of kidney failure and blindness, as well as a significant cause of non-traumatic lower limb amputations. In recent years, significant progress has been made in understanding the molecular mechanisms underlying both the disruption of glucose homeostasis and the pathophysiology of diabetes-associated complications.
This Special Issue of IJMS invites original research articles and comprehensive reviews that provide insight into type 2 diabetes and its complications. Topics of interest include, but are not limited to, the molecular and preclinical aspects of macrovascular complications—such as atherosclerosis, cardiovascular disease, and peripheral and foot artery disease—as well as microvascular complications including diabetic nephropathy, neuropathy, and retinopathy. Finally, we also aim to highlight the current and emerging therapeutic strategies designed to prevent or mitigate these complications.
We look forward to your valuable contributions.
Dr. Giuseppe Murdolo
Guest Editor
Manuscript Submission Information
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Keywords
- obesity
- insulin resistance
- type 2 diabetes
- atherosclerosis
- endothelial dysfunction
- cardiovascular disease
- peripheral artery disease
- diabetic feet
- diabetic micoangiopathy
- diabetic neuropathy
- regenerative medicine
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