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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Anti-cancer Agents: Design, Synthesis and Applications
edited by
submission deadline 20 Sep 2025 | 2 articles | Viewed by 1993 | Submission Open
Keywords: anti-cancer drugs; cancer drug development; cancer therapy; rational drug design; structure– activity relationship; cancer therapeutics; cytotoxicity; apoptosis; anti-tumor activity
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Insights into Flower Gene Regulation
edited by Wen‑Chieh Tsai
submission deadline 20 Sep 2025 | 2 articles | Viewed by 1989 | Submission Open
Keywords: floral gene regulation; flowers; homeotic genes; MADSBox; pollination
(This special issue belongs to the Section Molecular Plant Sciences)
Cellular Oxygen Homeostasis—3rd Edition
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1983 | Submission Open
Keywords: cellular oxygen homeostasis; redox signaling; cellular oxygen sensing; hypoxia; hyperoxia
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms and Treatment of Chronic Kidney Disease
edited by Xinming Chen
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1971 | Submission Open
Keywords: diabetes; cardiovascular diseases; nephrology; diabetic nephropathy
(This special issue belongs to the Section Molecular Biology)
Recent Research on Cardiac Troponins submission deadline 20 Sep 2025 | 2 articles | Viewed by 1967 | Submission Open
Keywords: cardiac troponin; gene mutations; post-translational modifications; therapy; high-sensitivity (hs) immunoassays; mechanisms of release; biomarkers; cardiovascular disease
(This special issue belongs to the Section Molecular Biology)
Molecular Research on Oxidative Stress in Health and Disease submission deadline 20 Sep 2025 | 1 articles | Viewed by 1956 | Submission Open
Keywords: oxidative stress; antioxidants; cancer; redox signalling; reactive oxygen and nitrogen species
(This special issue belongs to the Section Molecular Biology)
Antimicrobial Resistology: A New Approach in the Fight Against Antimicrobial Resistance
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1860 | Submission Open
Keywords: antimicrobial resistance; resistology; ESBL; AmpC; carbapenem resistance; one health
(This special issue belongs to the Section Molecular Pharmacology)
Blood Cells in Human Health and Disease
edited by Leonid Livshits
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1858 | Submission Open
Keywords: red blood cell; RBC membrane; RBC biophysical properties; RBC rheology; RBC mechanical properties; RBC membrane vesiculation; RBC clearance; RBC in diabetes; hemoglobinopathies; RBC storage TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Biochemistry)
Protein Stability Research: 2nd Edition
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1841 | Submission Open
Keywords: protein stability; protein degradation; conformational stability and flexibility; thermodynamic stability of proteins; mutation-induced changes in protein stability; stability of oligomeric proteins; stability of protein complexes; thermal adaptation of protein structures; protein aggregation; molten globules; heat shock proteins; chaperones
(This special issue belongs to the Section Molecular Biophysics)
Advanced Molecular Research on Retinopathy and Protection
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1833 | Submission Open
Keywords: retinopathy; neuroprotection; antioxidants; innovative therapy; emerging technology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Characterization and Biological Function of Plant Extracts submission deadline 20 Sep 2025 | 2 articles | Viewed by 1806 | Submission Open
Keywords: plant extracts; phytochemical characterization; bioactive compounds; biological activity; molecular mechanisms; gene expression; pharmacognosy
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Advances in Burn Wound Healing and Skin Regeneration: Innovations and Insights
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1795 | Submission Open
Keywords: burn wound healing; skin regeneration; novel biomaterials; wound dressings; regenerative therapies
(This special issue belongs to the Section Biochemistry)
Recent Advances in Retinal Neurobiology
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1788 | Submission Open
Keywords: retina; vision; disease; ganglion cells; amacrine cells; bipolar cells; horizontal cells; photoreceptors; astrocytes; microglia; Mü ller cells
(This special issue belongs to the Section Molecular Neurobiology)
Peptide Self-Assembly
edited by
submission deadline 20 Sep 2025 | 2 articles | Viewed by 1783 | Submission Open
Keywords: peptide assembly; aromatic short peptides; bioinspired supramolecular architectures; functional materials; peptide microfabrication; anticancer therapy; supercapacitor; biosensing
(This special issue belongs to the Section Macromolecules)
DNA Damage Response from Molecular Mechanisms to Cancer Therapy
edited by Luigi Alfano and
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1783 | Submission Open
Keywords: DNA damage response; synthetic lethality; homologous recombination; cancer therapy
(This special issue belongs to the Section Molecular Oncology)
Explore Marine Biodiversity: Discover Insights from Genomics and Transcriptomics
edited by and Ambrosino Luca
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1762 | Submission Open
Keywords: comparative genomics; functional genomics; transcriptomics; gene expression; adaptation; population genomics; marine biodiversity; evolution
(This special issue belongs to the Section Molecular Genetics and Genomics)
The Molecular Role of Platelets in Human Diseases submission deadline 20 Sep 2025 | 1 articles | Viewed by 1702 | Submission Open
Keywords: platelet; biomarkers; platelet membrane proteins; platelet-derived microparticles; platelet-related diseases; thrombosis; inflammatory diseases; cardiovascular disease; cancer; tumor growth and metastasis
(This special issue belongs to the Section Molecular Biology)
Electrochemistry: Molecular Advances and Challenges
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1686 | Submission Open
Keywords: fundamental electrochemistry; electroanalytical techniques; sensors and biosensors; nano-electrochemistry; electrochemical energy production and storage; environmental electrochemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Molecular Advances in Forensic Toxicology: Innovative Approaches in Detection of New Psychoactive Substances
edited by Roberta Tittarelli and Giulio Mannocchi
submission deadline 20 Sep 2025 | 2 articles | Viewed by 1660 | Submission Open
Keywords: addiction; new psychoactive substances; mass spectrometry; biological matrices; diversion; forensic toxicology; drug testing
(This special issue belongs to the Section Molecular Toxicology)
Chronic Liver Disease and Hepatocellular Carcinoma—2nd Edition
edited by and Sara Carpi
submission deadline 20 Sep 2025 | 2 articles | Viewed by 1657 | Submission Open
Keywords: hepatocellular carcinoma; NAFLD/NASH; viral hepatitis; autoimmune liver disease; immunotherapy; biomarker
(This special issue belongs to the Section Molecular Oncology)
Scleroderma: From Biomarkers to Therapeutic Targets
edited by Kathryn Seraphin Torok
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1631 | Submission Open
Keywords: scleroderma; biomarkers; epigenetics; RNA sequencing; genetics and genomics; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Research in Spatial Proteomics
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1625 | Submission Open
Keywords: spatial proteomics; mass spectrometry imaging; mass cytometry; biomarker; machine learning; spatial biology; molecular pathology; cancer
(This special issue belongs to the Section Molecular Informatics)
Reproductive Diseases and Modern Lifestyle: From Bench to Bedside submission deadline 20 Sep 2025 | 1 articles | Viewed by 1621 | Submission Open
Keywords: infertility; endocrine disrupting chemicals; reproductive hormones; lifestyle; metabolic diseases
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Amyotrophic Lateral Sclerosis Behind Motor Neurons
edited by and Ezia Guatteo
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1612 | Submission Open
Keywords: non-neuronal cells; neurotransmitters; systemic disease; motor system; neuronal circuitry; skeletal muscle metabolism; muscle oxidative metabolism
(This special issue belongs to the Section Molecular Neurobiology)
Pathophysiology and New Therapies of Alopecia
edited by Jong-Hyuk Sung
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1578 | Submission Open
Keywords: alopecia; pathophysiology; novel pharmacological treatments; regenerative medicines; gene therapy; cell therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Advances in the Field of Thrombosis and Hemostasis
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1564 | Submission Open
Keywords: bleeding; thrombosis; new diagnostic tests; rare diseases; platelet function; biomarkers; risk factors; thrombocytopenia; endothelial dysfunction; autoantibodies; extracellular vesicles; stem cells; gene therapy
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanism and Treatment of Diabetes Mellitus and Its Complications
edited by
submission deadline 20 Sep 2025 | 4 articles | Viewed by 1557 | Submission Open
Keywords: MODY; LADA; diabetes late complications; molecular mechanisms; omics; polyneuropathy; microvascular disease; macrovascular disease; liver disease
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Dynamics Simulation of Biomolecules
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1525 | Submission Open
Keywords: molecular dynamics simulations; biochemical processes; biomaterial properties
(This special issue belongs to the Section Molecular Biophysics)
Molecular Advances in Omics in Agriculture submission deadline 20 Sep 2025 | 2 articles | Viewed by 1520 | Submission Open
Keywords: agronomy; plant production; animal production; genome; microbiome; metagenomics; RNAseq; molecular mechnisms; molecular pest diagnostics; molecular interactions; gene editing
(This special issue belongs to the Section Molecular Informatics)
Characterization and Biological Functions of Plant Extracts submission deadline 20 Sep 2025 | 1 articles | Viewed by 1515 | Submission Open
Keywords: biological activity of plant-derived products; antimicrobial activity; in vitro antibiofilm activity; anticancer activity; anti-inflammatory activity; secondary metabolites
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Genetic Prediction of Risk of Common Diseases
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1514 | Submission Open
Keywords: complex genetic diseases; cancer; heart disease; diabetes; dementia; polygenic risk score; genetic risk signatures
(This special issue belongs to the Section Molecular Genetics and Genomics)
Reproductive Genetics and Epigenetics: Insights into Infertility Failures and Treatment Pathways
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1440 | Submission Open
Keywords: infertility; epigenetics; polymorphism; gametogenesis; fertilization; embryo development; reproductive organs; congenital malformations
(This special issue belongs to the Section Molecular Genetics and Genomics)
Human Hereditary Diseases: Advances in Molecular Genetics, Genomics and Therapeutic Strategies
edited by Yulin Jin and
submission deadline 20 Sep 2025 | 2 articles | Viewed by 1439 | Submission Open
Keywords: hereditary diseases; genetics and genomics; molecular mechanism; gene regulation; therapeutic approach
(This special issue belongs to the Section Molecular Genetics and Genomics)
Phytochemical Dynamics: Plant Metabolite Responses to Environmental Factors
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1436 | Submission Open
Keywords: plant metabolites; phytochemicals; biotic and abiotic factors; environmental influences; biochemical pathways; interactions
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Mechanism and Therapeutic Approaches of Breast Cancer, Metastatic Breast Cancer, 3rd Edition
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1407 | Submission Open
Keywords: breast cancer; metastatic breast cancer; epithelial-to-mesenchymal transition (EMT); epigenetic and post-translational modifications (PTM); tumor microenvironment
(This special issue belongs to the Section Molecular Oncology)
Molecular Research on Type 1 Diabetes and Its Complications: 2nd Edition submission deadline 20 Sep 2025 | 2 articles | Viewed by 1404 | Submission Open
Keywords: type 1 diabetes mellitus; diabetic microangiopathy; diabetic macroangiopathy; continuous glucose monitoring; experimental diabetic models; biomarkers; endothelium dysfunction; diabetes-related diseases; comorbidities; pregnancy; pathophysiology; metabolic syndrome; treatment; precision medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Chemistry Triggered by Low-Energy Particles
edited by Hassan Abdoul-Carime
submission deadline 20 Sep 2025 | 2 articles | Viewed by 1383 | Submission Open
Keywords: low energy (< 50 eV); photons; electrons; ions; gas phase; single molecules; clusters; condensed phase liquids and films; experimental techniques; density functional theory; IA-based prediction models
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Advances and Current Challenges in Plasma Medicine submission deadline 20 Sep 2025 | 1 articles | Viewed by 1382 | Submission Open
Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy; plasma and food; plasma and automotive; plasma and aerospace; plasma diagnostics; plasma material processing; plasma polymerization and coating; simulation of plasma phenomena during interaction with matter
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Investigation of Natural Products as Sources of Bioactive Molecules, 2nd Edition
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1370 | Submission Open
Keywords: metabolomic; secondary metabolites; phytochemical analysis; bioactivity; chemical investigation
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Glutamatergic Signaling in the Nervous System submission deadline 20 Sep 2025 | 1 articles | Viewed by 1347 | Submission Open
Keywords: glutamate glutamine cycle; neurotoxicty; ferroptosis; hyperglutamatergic states; innovative pharmacological interventions
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Advances in Electrochemical Materials
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1333 | Submission Open
Keywords: electrochemical materials; molecular design; energy storage; electrocatalysis; sensing applications; nanomaterials; sustainable materials; hybrid systems; interface engineering; green chemistry
(This special issue belongs to the Section Materials Science)
Drug-Induced Neurotoxicity and Neurodegeneration: Mechanisms, Models and Implications submission deadline 20 Sep 2025 | 1 articles | Viewed by 1322 | Submission Open
Keywords: drugs of abuse; pharmaceutical drugs; environmental toxins; drug exposure; neurotoxicity; neurodegeneration; brain health; substance use disorders; therapeutic interventions; in vivo models; in vitro models; in silico models; biomarkers of damage; translational studies
(This special issue belongs to the Section Molecular Neurobiology)
Type 1 Diabetes: Molecular Mechanisms and Therapeutic Approach
edited by Preeti Chhabra
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1301 | Submission Open
Keywords: type 1 diabetes; microbiome; proteomics; immunotherapy; β -cell replacement; single-cell sequencing; stem cells; gene editing technologies; tolerance
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Hybrid Organic–Inorganic Materials: From Synthesis to Applications submission deadline 20 Sep 2025 | 1 articles | Viewed by 1299 | Submission Open
Keywords: hybrid; organic– inorganic; functional materials; structure– property; design; synthesis
(This special issue belongs to the Section Materials Science)
Unraveling the Genetic Background of Neurological Disorders: 2nd Edition submission deadline 20 Sep 2025 | 1 articles | Viewed by 1293 | Submission Open
Keywords: neurological disorders; neurogenetics; personalized treatments; gene-association studies; genetics; genome-wide association studies; genetic linkage studies
(This special issue belongs to the Section Molecular Genetics and Genomics)
Cell Fate Decisions: Autophagy, Apoptosis, Pyroptosis, Necroptosis, Ferroptosis and PANoptosis in Health and Disease
edited by
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1288 | Submission Open
Keywords: inflammation; autophagy; apoptosis; pyroptosis; necroptosis; PANoptosis; ferroptosis; cell death; cell survival
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanism of Extracellular Vesicles in Human Diseases
edited by Eszter Ágnes Tóth
submission deadline 20 Sep 2025 | 1 articles | Viewed by 1251 | Submission Open
Keywords: extracellular vesicles; intercellular communication; disease pathophysiology; biomarkers; nanoscience; biomolecular interactions
(This special issue belongs to the Section Molecular Biology)
Mitochondria as a Therapeutic Target for Anti-Cancer Drugs submission deadline 20 Sep 2025 | Viewed by 1238 | Submission Open
Keywords: mitochondria; cancer; apoptosis; oxidative phosphorylation; Warburg effect; cardiolipin; inflammation
(This special issue belongs to the Section Molecular Oncology)
Gestational Diabetes Mellitus: Molecular Insights into Pathophysiology, Management and Therapy submission deadline 20 Sep 2025 | 2 articles | Viewed by 1226 | Submission Open
Keywords: GDM pathogenesis; health programming; pharmacogenomics; life-style interventions; fetal growth disorders; preeclampsia; polyhydramnios; placental origin of disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Glioblastoma: Molecular Pathogenesis and Treatment submission deadline 20 Sep 2025 | 1 articles | Viewed by 1194 | Submission Open
Keywords: glioblastoma; molecular therapy; pathogenesis; immunotherapy; brain tumor
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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