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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research and Insights into Anti-Cancer Vaccines
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1459 | Submission Open
Keywords: anti-cancer vaccines; tumor antigens; molecular mechanisms; immunotherapy; molecular oncology
(This special issue belongs to the Section Molecular Oncology)
Molecular Research in Functional Nanomaterials
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1436 | Submission Open
Keywords: functional materials; nanomaterials; molecular structure; molecular materials; functional molecules; nanotechnology; self-assembly methods
(This special issue belongs to the Section Molecular Nanoscience)
Evolutionary Drivers and Adaptive Mechanisms in Algal Organellar Genomes
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1433 | Submission Open
Keywords: organellar genome of algae; molecular evolution; secondary structure of intron; evolutionary driving force; horizontal gene transfer
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Biology of the Thyroid Cancer and Thyroid Dysfunctions: 2nd Edition
edited by Vija Lavinia
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1421 | Submission Open
Keywords: animal models; apoptosis; autophagy; cancer biomarker; cancer epidemiology; cancer prevention; cancer screening; cholesterol metabolism; clinical trial; DNA repair; epigenomics; genome instability; genomic database; genomics; invasion; metabolomics; metastasis; methylation; microarray; microRNA; molecular diagnostics; molecular tumor pathology; next-generation sequencing; noncoding RNA; omics; personalized medicine; prognosis; proteomics; radionuclide therapy; signaling pathway; SNP genotyping; targeted therapy; theranostics; thyroid cancer; hyperthyroidism; therapeutic targets; translational cancer research; treatment response; tumor microenvironment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Thromboinflammation
edited by Ana B. Arroyo
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1405 | Submission Open
Keywords: thromboinflammation; coagulation; inflammation; immune system; sepsis; stroke; autoimmune diseases; cancer; hematology; biomarkers; translational medicine
(This special issue belongs to the Section Molecular Immunology)
Application of Nanomedicine in Cancer Targeting and Treatment
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1372 | Submission Open
Keywords: nanomedicine; nanoimaging/bioimaging; cancer biology; theranostics; translational nanomedicine
(This special issue belongs to the Section Molecular Nanoscience)
The Latest Molecular Insights into Animal Nutrition
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 1342 | Submission Open
Keywords: reproduction; animal production; development; immunity; emissions; digestion efficiency; microbiome; metabolism; molecular signaling; nutritional strategies
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular Research in Protein–Ligand Interactions
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1321 | Submission Open
Keywords: interaction; protein– ligand; computer simulation; docking; molecular simulation
(This special issue belongs to the Section Biochemistry)
AIEgens in Action: Design, Mechanisms, and Emerging Applications submission deadline 20 Aug 2026 | 1 articles | Viewed by 1321 | Submission Open
Keywords: fluorescence effects; photophysical properties of small molecules; ion detection; molecular spectroscopy; various nanoparticle-based additives; fluorescent and phosphorescent phenomena in solvents; amorphous states; and crystals; quantum-mechanical calculations for molecular systems and compositions (DFT; TD-DFT); molecular aggregation influencing fluorescence and phosphorescence properties of tested systems
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Molecular and Electrochemical Mechanisms of Metal Corrosion
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1310 | Submission Open
Keywords: metal corrosion; molecular mechanisms; electrochemistry; surface chemistry; corrosion inhibitors; passivation
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Autoimmune Diseases: From Molecular Mechanisms to Therapeutic Innovations submission deadline 20 Aug 2026 | 1 articles | Viewed by 1300 | Submission Open
Keywords: autoimmunity; biological biomarkers; personalized therapies; biologics and JAK inhibitors; CAR-T cell therapy
(This special issue belongs to the Section Molecular Immunology)
State-of-the-Art Electrochemical Reaction Technologies submission deadline 20 Aug 2026 | 1 articles | Viewed by 1300 | Submission Open
Keywords: energy storage; electrochemical sensors; electrocatalysis; supercapacitors; molecular electrochemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Research Progress of Fluorescent Proteins in Molecular Biology
edited by Matteo Grenzi
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1298 | Submission Open
Keywords: fluorescence microscopy; fluorescence live-cell imaging; quantitative imaging; fluorescent biosensors; in vivo imaging; innovative fluorescence microscopy techniques
(This special issue belongs to the Section Molecular Biology)
Decoding the Microbial Influence on Host Gene Expression submission deadline 20 Aug 2026 | 1 articles | Viewed by 1296 | Submission Open
Keywords: microbiota; host; gene expression; in silico; bioinformatics; in vitro; in vivo
(This special issue belongs to the Section Molecular Microbiology)
Unknown Pathogenesis of Musculoskeletal Diseases and Basic Sciences: The Role of New Technologies
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1286 | Submission Open
Keywords: AI; musculoskeletal diseases; pathogenesis; basic sciences; molecular mechanisms; genetics; immunology; biomechanics; translational research; experimental models; tissue engineering
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Artificial Intelligence Advancing Computer-Aided Drug Discovery
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1243 | Submission Open
Keywords: machine learning; deep learning; computer-aided drug design; target identification; AI-assisted molecular diagnosis; AI-driven pharmacokinetic profiling; virtual screening; network pharmacology; drug repurposing; molecular dynamics simulation; computational chemistry; AI in nanotechnology
(This special issue belongs to the Section Molecular Informatics)
Molecular Insights into Microbial Adaptations to Marine Plastics
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1224 | Submission Open
Keywords: plastisphere; marine plastic debris; microbial colonization; biofilms; microbial adaptation; community assembly; quorum sesing; plastic biodegradation; biogeochemical cycling; antibiotic resistance genes; marine microbial ecology; metagenomics; microbe– plastic interactions; microbial succession
(This special issue belongs to the Section Molecular Microbiology)
RNA Biology: Unraveling the Complex Interplay Between Proteins and RNAs in Gene Expression and Regulation, 2nd Edition
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1197 | Submission Open
Keywords: RNA biology; protein– RNA interplay; gene expression; post-transcriptional modifications; non-coding RNAs
(This special issue belongs to the Section Molecular Genetics and Genomics)
Molecular Advances in Heart Disease: Genomics and Bioinformatics of Heart Research—2nd Edition
edited by Justyna Fert-Bober
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1185 | Submission Open
Keywords: heart disease; cardiovascular disease; coronary artery disease (CAD); heart attack; heart failure; arrhythmia (abnormal heart rhythms); valve disease; high blood pressure; congenital heart conditions; inherited heart conditions; fibrosis; pathobiology of fibrosis; aging; chronic inflammation; inflammatory and cardiovascular diseases; myocarditis; extracellular matrix biology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Dendritic Cell-Based Immunotherapy of Cancer
edited by Helena Haque Chowdhury and Matjaz Jeras
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1162 | Submission Open
Keywords: DC-based immunotherapy of cancer; immunostimulatory dendritic cell (DC) generation; dosage and routes of DC administration; body distribution of DCs post-application; frequency and duration of DC applications; tumour immunosuppressive mechanisms’ modulation; combinatorial DC-based anticancer immunotherapy
(This special issue belongs to the Section Molecular Immunology)
Chemical Tools for Microbial Functionalization: Bridging Organic Chemistry and Biotechnology
edited by Stefania Cicco and
submission deadline 20 Aug 2026 | Viewed by 1150 | Submission Open
Keywords: organometallic biochemistry; green chemistry; bioorthogonal; living polymers; living functionalization; hybrid materials
(This special issue belongs to the Section Molecular Microbiology)
The Role of Diet in Lipid and Lipoprotein Metabolism
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1138 | Submission Open
Keywords: dyslipidemia; hypertension; diabetes; dementia
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Recent Advances in Brain Tumor Research and Treatment submission deadline 20 Aug 2026 | 1 articles | Viewed by 1137 | Submission Open
Keywords: brain tumor; gliomas; brain metastases; translational research; molecular biology
(This special issue belongs to the Section Molecular Oncology)
Rewriting Medicine: Stem Cells and Regeneration
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1115 | Submission Open
Keywords: regenerative medicine; stem cell biology; stem cell therapy; induced pluripotent stem cell; tissue engineering
(This special issue belongs to the Section Molecular Biology)
Pregnancy-Related Complications: Molecular Pathogenesis and Therapeutic Strategies
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1107 | Submission Open
Keywords: pregnancy-related complications; placental dysfunction; maternal-fetal communication; extracellular vesicles; translational research; biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular and Cellular Basis of Oral Immunology
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1099 | Submission Open
Keywords: oral immunology; oral mucosa; immune tolerance; oral microbiome; oral diseases; periodontium; innate immunity; adaptive immunity
(This special issue belongs to the Section Molecular Immunology)
Fractalkine (CX3CL1) and Its Chemoattractant and Adhesion Molecule Properties in Health and Disease, 2nd Edition
edited by Dariusz Szukiewicz
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1098 | Submission Open
Keywords: fractalkine; transmembrane fractalkine; soluble fractalkine; fractalkine receptor; CX3CL1-CX3CR1 signaling; inflammation; chemokine; cell adhesion; chemotaxis; immune response; angiogenesis; implantation; atherosclerosis; carcinogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Optical, Electrical, and Thermal Materials: Recent Advances and Challenges
edited by Luyi Zou
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1089 | Submission Open
Keywords: optical materials; electrical materials; thermal materials; molecular structure; molecular composition; structural performance
(This special issue belongs to the Section Materials Science)
Structure, Properties, and Applications of Carbon Materials submission deadline 20 Aug 2026 | 1 articles | Viewed by 1067 | Submission Open
Keywords: carbon-based structures; diamonds; carbon quantum dots; carbon composites; graphene; nanotubes
(This special issue belongs to the Section Materials Science)
New Progress in Peptidic Protease Inhibitors
edited by and Carla Di Chio
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1064 | Submission Open
Keywords: peptide inhibitors; infectious diseases; cancer; metabolic disorders; neurological disorders; inflammation
(This special issue belongs to the Section Biochemistry)
Telocytes: Unraveling Their Roles in Health and Disease
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1058 | Submission Open
Keywords: telocytes; telopodes; intercellular communication; stem cell niche; extracellular vesicles; regenerative medicine; tissue remodelling; stromal cells
(This special issue belongs to the Section Molecular Biology)
Advances in Research of Estrogen Receptors in Health and Diseases submission deadline 20 Aug 2026 | 1 articles | Viewed by 1047 | Submission Open
Keywords: estrogen receptors; physiology; pathobiology; cancer; benign diseases and disorders
(This special issue belongs to the Section Biochemistry)
Coordination Chemistry: From Fundamental Principles to Multifunctional Applications
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1013 | Submission Open
Keywords: coordination compounds; metal– ligand interactions; ligand design and synthesis; spectroscopic characterization; coordination geometry; molecular architecture; ion-association complexes; supramolecular chemistry; catalysis and activation mechanisms; functional materials; metal– organic frameworks; magnetism in coordination compounds; redox-active complexes; environmental and green chemistry applications; sensors and molecular devices; bioinorganic chemistry; medicinal coordination chemistry; theoretical and computational coordination chemistry
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Research on the Key Role of Ubiquitination in Signaling and Cancer
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 1007 | Submission Open
Keywords: ubiquitin; ubiquitination; E3 ligase; deubiquitinating enzymes; protein degradation; mutations; cancer progression; signal transduction; drug development
(This special issue belongs to the Section Molecular Oncology)
Molecular Biology on Environmental Microorganisms
edited by
submission deadline 20 Aug 2026 | 2 articles | Viewed by 988 | Submission Open
Keywords: environmental microbiology; metagenomics; microbial interactions; phage– host dynamics; horizontal gene transfer; biogeochemical cycles; antimicrobial resistance; single-cell methods; microbiome engineering; environmental biotechnology
(This special issue belongs to the Section Molecular Microbiology)
Systems Approaches to Diabetic Complications
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 953 | Submission Open
Keywords: diabetes; diabetic complications; molecular mechanisms; precision medicine
(This special issue belongs to the Section Molecular Biology)
New Insight into Bacteriophage and Their Potential Applications
edited by Wilfried Moreira
submission deadline 20 Aug 2026 | 1 articles | Viewed by 950 | Submission Open
Keywords: bacteriophage; phage biology; phage-host interactions; antimicrobial resistance
(This special issue belongs to the Section Molecular Microbiology)
Endothelial Cells in Vascular Health and Immunity
edited by and Xianming Zhang
submission deadline 20 Aug 2026 | 1 articles | Viewed by 929 | Submission Open
Keywords: endothelial cells; vascular health; cardiovascular disease; kidney disease; lung injury; inflammation; regenerative medicine; molecular therapy
(This special issue belongs to the Section Biochemistry)
Current Research on Phenolic Profiles and Anti-Inflammatory Activities of Plants
edited by Chi-Rei Wu and Li-Wei Lin
submission deadline 20 Aug 2026 | 1 articles | Viewed by 867 | Submission Open
Keywords: plants; phenolic profiles; inflammation; cardiovascular disorders; cancer; diabetes; neurodegenerative disorders
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Effects of Radiation in Health and Disease submission deadline 20 Aug 2026 | 1 articles | Viewed by 863 | Submission Open
Keywords: extremely low-frequency magnetic fields; proteins and gene interaction; ionizing and non-ionizing radiations
(This special issue belongs to the Section Molecular Biology)
Molecular Research in Renal Endocrinology submission deadline 20 Aug 2026 | 1 articles | Viewed by 838 | Submission Open
Keywords: renin– angiotensin system; natriuretic peptides; calcitriol; erythropoietin; prostaglandins; endothelins; adrenomedullin
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Carbon Fiber, Carbon Nanofiber for Composites: Synthesis, Processing, Molecular Structure, Characterization, and Application
edited by Tridung Ngo
submission deadline 20 Aug 2026 | Viewed by 815 | Submission Open
Keywords: carbon fiber; carbon nanofiber; nanotube; carbon fiber composites; synthesis; advanced manufacturing; characterization; recent advancements; applications
(This special issue belongs to the Section Materials Science)
MicroRNAs as Biomarkers in Chronic Diseases
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 808 | Submission Open
Keywords: microRNA; biomarker; chronic diseases; cancer; cardiovascular diseases; psychiatric conditions
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bioinformatics Analysis of Single Cell and Spatial Multi-Omics
edited by Fahong Yu
submission deadline 20 Aug 2026 | Viewed by 783 | Submission Open
Keywords: bioinformatics; single-cell omics; spatial multi-omics; matabolomics; genomics; transcriptomics; proteomics; next-generation sequencing techniques
(This special issue belongs to the Section Molecular Informatics)
Immune Responses, Viral Infection and Neurodegenerative Diseases
edited by and Barbara Hanson
submission deadline 20 Aug 2026 | 1 articles | Viewed by 774 | Submission Open
Keywords: immune response; innate immunity; viral neuropathogenesis; viral biomarker; AD; PD; neurodegenerative diseases
(This special issue belongs to the Section Molecular Immunology)
Molecular Insights into Innovative Materials and Procedures for Implant and Prosthodontics submission deadline 20 Aug 2026 | Viewed by 712 | Submission Open
Keywords: alloys; biomaterials; dental materials; dental implants; implant dentistry; implant-abutment connection; peri-implant diseases; prosthodontics; surface treatments; tissue regeneration
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Plant Responses to Abiotic Stress: Mechanisms and Adaptations submission deadline 20 Aug 2026 | Viewed by 696 | Submission Open
Keywords: salinity stress; heat and cold stress; oxidative stress; signal transduction; stress-responsive genes; antioxidant defence mechanisms; hormonal regulation; molecular adaptation; epigenetic regulation; plant-microbe interaction; crop improvement; stress-resilient plants
(This special issue belongs to the Section Molecular Plant Sciences)
Tumor Viruses: Infection, Carcinogenesis, and Treatment
edited by
submission deadline 20 Aug 2026 | 1 articles | Viewed by 689 | Submission Open
Keywords: tumor viruses; viral oncogenesis; EBV; HPV; KSHV; HBV; HCV; HTLV-1; and MCPyV; virus-associated cancers; merging oncoviruses; viral latency; immune evasion; antiviral therapy; immunotherapy; cancer vaccines; gene-editing technologies
(This special issue belongs to the Section Molecular Microbiology)
Neuroinflammation, and Alcohol Use Disorders: Molecular Mechanisms and Treatment
edited by
submission deadline 20 Aug 2026 | Viewed by 674 | Submission Open
Keywords: alcohol; addiction; abuse; inflammation; neurodegeneration; cognition; neuroimmunology; oxidative stress
(This special issue belongs to the Section Molecular Biology)
Health-Promoting Benefits of Natural Products and Functional Foods, 2nd Edition
edited by
submission deadline 20 Aug 2026 | Viewed by 646 | Submission Open
Keywords: natural products; functional foods; health promotion; nutrigenomics; evidence-based preventive healthcare; phytochemicals; biomarkers; chronic diseases
(This special issue belongs to the Section Bioactives and Nutraceuticals)
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