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Review

Cytokines in Inflammatory Disease

by 1,2,†, 3,† and 4,*
1
Experimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany
2
Department of Cardiology with Emphasis on Electrophysiology, University Heart Centre, University Hospital Hamburg-Eppendorf, 20251 Hamburg, Germany
3
Department of Trauma, Hand and Reconstructive Surgery, Goethe University, 60590 Frankfurt, Germany
4
Experimental Radiology, Department of Radiology and Nuclear Medicine, Otto von Guericke University Magdeburg, 39120 Magdeburg, Germany
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Int. J. Mol. Sci. 2019, 20(23), 6008; https://doi.org/10.3390/ijms20236008
Received: 4 October 2019 / Revised: 24 November 2019 / Accepted: 25 November 2019 / Published: 28 November 2019
(This article belongs to the Special Issue Metabolic Bone Diseases: Pathophysiology and Molecular Biology)
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines. Numerous studies have implicated that inflammatory cytokines exert important effects with regard to various inflammatory diseases, yet the reports on their specific roles are not always consistent. They can be used as biomarkers to indicate or monitor disease or its progress, and also may serve as clinically applicable parameters for therapies. Yet, their precise role is not always clearly defined. Thus, in this review, we focus on the existing literature dealing with the biology of cytokines interleukin (IL)-6, IL-1, IL-33, tumor necrosis factor-alpha (TNF-α), IL-10, and IL-8. We will briefly focus on the correlations and role of these inflammatory mediators in the genesis of inflammatory impacts (e.g., shock, trauma, immune dysregulation, osteoporosis, and/or critical illness). View Full-Text
Keywords: inflammation; disease; interleukin inflammation; disease; interleukin
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MDPI and ACS Style

Kany, S.; Vollrath, J.T.; Relja, B. Cytokines in Inflammatory Disease. Int. J. Mol. Sci. 2019, 20, 6008. https://doi.org/10.3390/ijms20236008

AMA Style

Kany S, Vollrath JT, Relja B. Cytokines in Inflammatory Disease. International Journal of Molecular Sciences. 2019; 20(23):6008. https://doi.org/10.3390/ijms20236008

Chicago/Turabian Style

Kany, Shinwan, Jan T. Vollrath, and Borna Relja. 2019. "Cytokines in Inflammatory Disease" International Journal of Molecular Sciences 20, no. 23: 6008. https://doi.org/10.3390/ijms20236008

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