Bioengineering, Volume 10, Issue 9
2023 September - 117 articles
Cover Story: Muscle tissue engineering aims to repair or regenerate defective muscle tissue lost by trauma or disease. Despite its great potential, the number of clinical trials in this field is very limited. In this context, several parameters need to be addressed towards the development of advanced regenerative therapies employing myogenic cells. Bioprocess considerations covering the cell isolation step starting from different tissue sources (i.e., stem/progenitor cells vs. more committed precursors), as well as the need for robust and cost-effective protocols featuring easy scalability envisioning clinical applications, which are approached herein. Overall, the ultimate goal would be to obtain clinically relevant cell numbers, while maintaining cell/tissue identity and functionality. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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