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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Machine Learning and Medicine: The Interface of Medicine, Engineering and Artificial Intelligence

edited by Simon W. Rabkin

submission deadline 31 May 2025 | 9 articles | Viewed by 21268

Keywords: medical informatics; healthcare analytics; predictive modeling; digital health; precision medicine; machine learning; artificial intelligence

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence and Machine Learning in Spine Research

edited by

Min Cheol Chang

submission deadline 31 May 2025 | 8 articles | Viewed by 15239

Keywords: spinal disorder; artificial intelligence; machine learning

(This special issue belongs to the Section Biosignal Processing)

Application of Deep Learning in Medical Diagnosis

edited by

Zhanlin Ji

and

Li Zhao

submission deadline 31 May 2025 | 7 articles | Viewed by 11905

Keywords: deep learning; artificial intelligence; medical image segmentation; medical image target detection; medical image classification; computer-assisted therapy

(This special issue belongs to the Section Biosignal Processing)

Functionalization of Dental Materials towards Improved Interaction with the Oral Environment

edited by

Nicoleta Ilie

and

Andrei Cristian Ionescu

submission deadline 31 May 2025 | 4 articles | Viewed by 11091

Keywords: resin composites; bioreactors; oral biofilms; microbial adherence; biofilm formation; bioactivity; controlled release; toxicity; surface texturing; surface characterization; aging; accelerated aging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Drug Delivery Systems for Cancer Treatment

edited by

Wujie Zhang

submission deadline 31 May 2025 | 3 articles | Viewed by 10353

Keywords: drug delivery; cancer treatment; controlled release; sustained release; drug targeting; microcarrier; nanocarrier; tumor microenvironment-responsive; cancer stem-like cells

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Novel, Low Cost Technologies for Cancer Diagnostics and Therapeutics

edited by

Brian T. Crouch

and

Jenna Mueller

submission deadline 31 May 2025 | 3 articles | Viewed by 6495

Keywords: low-cost cancer diagnostics; low-cost cancer therapeutics; point-of-care technology; see and treat; global health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancements in Medical Imaging Technology

edited by

Yuling Yan

submission deadline 31 May 2025 | 6 articles | Viewed by 4681

Keywords: diagnostic imaging; image reconstruction and analysis; computer-aided diagnosis; deep learning

(This special issue belongs to the Section Biosignal Processing)

Biological Tissue Regeneration Using Medical Materials

edited by

Osamu Yamamoto

Osamu Suzuki

and Norio Fukuda

submission deadline 31 May 2025 | 3 articles | Viewed by 4158

Keywords: ceramics; polymers; metals; gel; collagen; in vivo/in vitro evaluation; cells; animal model; clinical trial; biological tissue regeneration

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomedical Application of Big Data and Artificial Intelligence—Second Edition

edited by

Yan Pei

and

Jijiang Yang

submission deadline 31 May 2025 | 2 articles | Viewed by 4156

Keywords: artificial intelligence; big data; image processing; data mining; soft computing; bioinformatics; bioengineering; healthcare

(This special issue belongs to the Section Biosignal Processing)

Novel Treatment Technologies in Physical Medicine and Rehabilitation

edited by Ross Bogey

submission deadline 31 May 2025 | 1 articles | Viewed by 2594

Keywords: spinal cord injury; stroke; robotic assisted; gait training; physical therapy; rehabilitation medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

AI and Data Science in Bioengineering: Innovations and Applications

edited by

Muneer Ahmad

submission deadline 31 May 2025 | 1 articles | Viewed by 2263

Keywords: AI; data science; bioengineering; biomedical engineering; predictive modeling; machine learning; smart biomaterials; tissue engineering

(This special issue belongs to the Section Biosignal Processing)

Blue Economy: Innovative Strategies for Valorising Micro- and Macroalgae

edited by

José Carlos Magalhães Pires

and Tânia Tavares

submission deadline 31 May 2025 | 1 articles | Viewed by 2168

Keywords: blue economy; microalgae; microscopic aquatic plants; macroalgae; valuable compounds

(This special issue belongs to the Section Biochemical Engineering)

Bioengineering Strategies for Cardiac Tissue

edited by Mohamed Ghorbel

submission deadline 31 May 2025 | 1 articles | Viewed by 1958

Keywords: congenital heart disease; cardiovascular disease modeling; corrective heart surgery; bioengineering; cardiovascular tissue; stem cells; vascular grafts; cardiac patches; 3D bioprinting; biomaterials

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence and Computational Simulations in Cardiovascular System

edited by

John F. LaDisa

submission deadline 31 May 2025 | 1 articles | Viewed by 1595

Keywords: artificial intelligence; computational simulations; cardiovascular system; computational fluid dynamics

(This special issue belongs to the Section Biosignal Processing)

Surgical Wound Infections and Management

edited by Sharon Henry and

Marcelo A. F. Ribeiro Jr.

submission deadline 31 May 2025 | 2 articles | Viewed by 1454

Keywords: surgical wound infections; epidemiology; incidence; risk factors; prophylactic antibiotics; antiseptic techniques; patient outcomes; complications; postoperative care; vulnerable populations; burn wound infection; antimicrobials; bioengineered materials for wounds and infections

(This special issue belongs to the Section Regenerative Engineering)

Micro- and Nano-Technologies for Cell Analysis

edited by Hidetaka Ueno and

Shohei Yamamura

submission deadline 31 May 2025 | 1 articles | Viewed by 1413

Keywords: cell-based assay; high-throughput screening; diagnosis; tissue engineering; micro- and nano-technology; cell chip; lab on a chip; BioMEMS; 3D-printed device; biosensor

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Measuring Outcomes and Impact Related to Assistive Technology and Accessibility for Disability

edited by Rochelle Mendonca, Qussai Obiedat and Roger O. Smith

submission deadline 31 May 2025 | 1 articles | Viewed by 1250

Keywords: assistive technology; disability; accessibility; measurement; outcomes; universal design

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Approaches for Brain and Spinal Cord Injuries

edited by Anita Singh

submission deadline 31 May 2025 | 1 articles | Viewed by 1116

Keywords: injury biomechanics; brain injury; spinal cord injury; birth related injuries; impact biomechanics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Tissue Engineering and Regenerative Medicine Strategies for Biomedical Engineering

edited by Hun Jin Jeong and

Solaiman Tarafder

submission deadline 31 May 2025 | 2 articles | Viewed by 961

Keywords: tissue engineering; regenerative medicine; bioprinting; microfluidics; tissues on chip

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Extracellular Vesicles in Regenerative Medicine

edited by Rohit K. Srivastava and

Shreyas Kuddannaya

submission deadline 31 May 2025 | Viewed by 727

Keywords: extracellular vesicles; regenerative medicine; drug delivery; tissue repair; exosomes; cancer; cell-to-cell communication

(This special issue belongs to the Section Regenerative Engineering)

Novel Fiber-Based Scaffolds for Tissue Engineering and Regenerative Medicine

edited by Mohamadmahdi Samandari and

Mohsen Akbari

submission deadline 31 May 2025 | Viewed by 713

Keywords: tissue engineering; regeneration; electrospinning; 3D (bio)printing; wet spinning; in vivo scaffold fabrication

(This special issue belongs to the Section Regenerative Engineering)

Advances in Medical 3D Vision: Voxels and Beyond

edited by Jiancheng Yang, Hongwei Li and Hieu Le

submission deadline 31 May 2025 | 2 articles | Viewed by 610

Keywords: medical 3D vision; artificial intelligence for health; 3D medical image analysis; voxel-based imaging; point clouds; mesh-based analysis; graph neural networks; implicit representations; deep geometric learning; interventional imaging; healthcare applications; digital twins

(This special issue belongs to the Section Biosignal Processing)

AI-Driven Innovations in Computational Histology/Pathology

edited by

Masataka Kawai

and

Kenta Masui

submission deadline 31 May 2025 | 1 articles | Viewed by 493

Keywords: generative models; multi-instance learning; self-supervised learning; pathology foundation models

(This special issue belongs to the Section Biosignal Processing)

Innovative Materials, Instrumentation, and Techniques in Endodontics

edited by

Dario Di Nardo

and

Rodolfo Reda

submission deadline 31 May 2025 | Viewed by 349

Keywords: endodontics; innovative materials; instrumentation; techniques; electronic devices; endodontic instrumentation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

The Application of Additive Manufacturing in the Biomedical Field

edited by Fengyuan Liu and

Cian Vyas

submission deadline 31 May 2025 | Viewed by 221

Keywords: additive manufacturing; biomedical field; 3D printing; bioprinting; personalized medicine; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Solutions for Sports Performance and Recovery

edited by

Germán Díaz Ureña

and Cristina Gonzalez-Millan

submission deadline 31 May 2025 | Viewed by 219

Keywords: sports medicine; rehabilitation engineering; wearable devices; biomechanics; performance optimization; health monitoring; robotic-assisted therapy

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Recent Advances in the Application of Deep Learning and Prediction Models in Biomedicine

edited by

Fangyao Chen

submission deadline 31 May 2025 | Viewed by 198

Keywords: deep learning; biomedical data mining; precision medicine and health; clinical decision making; multimodal data analysis

(This special issue belongs to the Section Biosignal Processing)

Advances and Applications of Neuroimaging

edited by Richard James Addante and Sujoy Ghosh-Hajra

submission deadline 31 May 2025 | Viewed by 160

Keywords: neuroimaging; fMRI; EEG; ERPs; TMS; tDCS; tACS; rTMS; MRI; PET; iEEG; sEEG

(This special issue belongs to the Section Biosignal Processing)

mRNA Nanomedicine: Bridging Material Science and Therapeutic Innovation

edited by

Zhiwei Fang

and Yonger Xue

submission deadline 31 May 2025 | Viewed by 155

Keywords: nanomaterials; mRNA; vaccines; targeted delivery; structural design

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Biosensors for 3D Engineered Cell Cultures

edited by Verena Charwat and Antonia Silvestri

submission deadline 31 May 2025 | Viewed by 139

Keywords: biosensors; 3D cell culture; microengineering; in vitro test systems; microtissues

(This special issue belongs to the Section Regenerative Engineering)

Preclinical Evaluation of Biomaterials and Medical Devices for the Musculoskeletal System

edited by

Silvia Brogini

and Matilde Tschon

submission deadline 15 Jun 2025 | 1 articles | Viewed by 2193 | Submission Open

Keywords: biomaterials and medical devices; preclinical testing; humanized advanced in vitro models; orthopaedic applications

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Fundamentals and Novel Applications of Fluid Mechanics, Biomechanics, and Acoustics in Biomedical Engineering, 2nd Edition

edited by

Iris Little

and

Ephraim Gutmark

submission deadline 15 Jun 2025 | 2 articles | Viewed by 1801 | Submission Open

Keywords: hemodynamics; cardiovascular flow; sleep; airway; voice; bioacoustics; biomechanics; bioflows; CFD; FSI; AI; ML

Wearable Integrated Sensors and Devices

edited by Shideh Kabiri Ameri

submission deadline 15 Jun 2025 | Viewed by 204 | Submission Open

Keywords: wearables; integrated wearable sensors; mobile healthcare; virtual reality; body sensor network; human– machine interface

(This special issue belongs to the Section Biosignal Processing)

New Sight for the Treatment of Dental Diseases: Updates and Direction

edited by

Angelo Michele Inchingolo

submission deadline 20 Jun 2025 | 3 articles | Viewed by 23037 | Submission Open

(This special issue belongs to the Section Regenerative Engineering)

The Power of Models and Simulation Tools in Biomedical and Biochemical Engineering

edited by

Antonio D’Ambrosio

Nicole Guazzelli

and

Leone Mazzeo

submission deadline 20 Jun 2025 | 4 articles | Viewed by 4210 | Submission Open

Keywords: computational simulation of sustainable processes; bioreactor modeling; modeling and optimization of the production of biofuels and bio-based products; bioprocesses intensification; membranes and biotechnology applications in biochemical and biomedical engineering; physiologically-based pharmacokinetic (PBPK) models; artificial organs modeling; simulation and optimization

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomechanical Analysis of Brain Tissue Injury and Bone Failure

edited by

Ghodrat Karami

submission deadline 20 Jun 2025 | Viewed by 317 | Submission Open

Keywords: tissue biomechanics; brain injury biomechanics; bones and orthopedic biomechanics

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Cardiac Tissue Engineering: From Tissue Regeneration to In Vitro Tissue Models

edited by

Elisabetta Rosellini

and Laurie Boyer

submission deadline 20 Jun 2025 | Viewed by 134 | Submission Open

Keywords: cardiac tissue engineering; heart-on-a-chip; stem cell therapy

(This special issue belongs to the Section Regenerative Engineering)

Advances in Bone Regeneration with Multipotential Stromal Cells and Bioactive Materials

edited by

Elena A. Jones

Jehan J. El-Jawhari

and

Dimitrios Kouroupis

submission deadline 30 Jun 2025 | 10 articles | Viewed by 28765 | Submission Open

Keywords: multipotential stromal/mesenchymal stem cells (MSCs); bone regeneration; cell engineering; activated matrices; sensors and imaging; scaffolds and biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Recent Advances in Machine Learning and Explainable Artificial Intelligence in Biomedical Data Mining, and Disease Diagnosis Frameworks

edited by

Amad Zafar

submission deadline 30 Jun 2025 | 9 articles | Viewed by 15414 | Submission Open

Keywords: EEG; fNIRS; MRI; X-rays; biomedical signal and image processing; machine learning; explainable artificial intelligence; biomedical data mining; computer-aided diagnosis; brain– computer interfaces; healthcare

(This special issue belongs to the Section Biosignal Processing)

Smart Engineering: Integrating Artificial Intelligence and Bioengineering

edited by

Daniele Giansanti

submission deadline 30 Jun 2025 | 3 articles | Viewed by 12215 | Submission Open

Keywords: bioengineering; smart engineering; artificial Intelligence; care robots; wearable devices; medical devices; mobile health; biomedical instrumentation; deep learning; machine learning; IoT

Biomechanics of Orthopaedic Rehabilitation

edited by Songning Zhang

submission deadline 30 Jun 2025 | 8 articles | Viewed by 11077 | Submission Open

Keywords: orthopedic; rehabilitation; joint arthroplasty; biomechanics; osteoarthritis; rehabilitation; pain; muscle; gait; cycling; muscle activation inhibition

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Applications of Bioprinting in Biomedicine

edited by

Chunya Wu

and

Lihua Lu

submission deadline 30 Jun 2025 | 4 articles | Viewed by 10631 | Submission Open

Keywords: bioprinting technology; bioink; bioprinting processes; bioprinter

(This special issue belongs to the Section Regenerative Engineering)

Spine Biomechanics

edited by Christian Liebsch

submission deadline 30 Jun 2025 | 9 articles | Viewed by 8710 | Submission Open

Keywords: biomechanics; spine; intervertebral disc; experiment; modeling; in vivo; in vitro; in silico

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Robotic Assisted Rehabilitation and Therapy

edited by

Carlos A. Jara

and

Andres Ubeda

submission deadline 30 Jun 2025 | 4 articles | Viewed by 8174 | Submission Open

Keywords: assistive rehabilitation robotics; electromyography (EMG); electroencephalography (EEG); computer vision and AI algorithms; exoskeletons or exosuits for assistance/rehabilitation; collaborative manipulators for assistive rehabilitation therapy

(This special issue belongs to the Section Biosignal Processing)

Advanced Biomaterials, Coatings, and Techniques: Applications in Medicine

edited by Yong Hou

submission deadline 30 Jun 2025 | 5 articles | Viewed by 7628 | Submission Open

Keywords: biomaterials; coatings; advanced techniques; medical devices; implants; tissue engineering; biocompatibility; 3D printing; nanotechnology; surface modification

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Regenerative Technologies in Plastic and Reconstructive Surgery

edited by Alanna M. Rebecca,

Joris A. van Dongen

and

Steven Paul Nistico

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5320 | Submission Open

Keywords: plastic surgery; reconstructive surgery; tissue engineering; burn reconstruction; biomaterials; 3D bioprinting; regenerative medicine

(This special issue belongs to the Section Regenerative Engineering)

Advanced Technology for Implant Polymers in Orthopaedics, Spine, and Trauma

edited by Steven M. Kurtz, Hannah Spece,

Pierangiola Bracco

and

Francisco Javier Medel

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4943 | Submission Open

Keywords: UHMWPE; highly crosslinked UHMWPE; HXLPE; PEEK; PEKK; PAEK; additive manufacturing; AM; 3D printing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomechanics of Physical Exercise

edited by

Andrea Biscarini

submission deadline 30 Jun 2025 | 5 articles | Viewed by 4354 | Submission Open

Keywords: biomechanics; kinematics; kinetics; muscle activation; joint loads; proprioception; postural control and balance; neuromotor control; human movement; physical exercise; athletic training; athletic performance; sport; injury prevention; rehabilitation; exercise equipment; equipment design; ergonomics; motion analysis; force plates; electromyography; EMG; musculoskeletal modelling; simulation; sensors; imaging; magnetic resonance; MRI; artificial intelligence; robotics; new technologies

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Cutting-Edge Applications of Machine and Deep Learning in Biomedical Signal and Image Processing

edited by