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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Feature Papers in Biomedical Engineering and Biomaterials

edited by

Andrea Cataldo

Christian Demitri

and

Emanuele Piuzzi

submission deadline 30 Apr 2025 | 11 articles | Viewed by 47657 | Submission Open

Keywords: development; design and characterization of biomaterials; biological tissues and bio-systems; bioengineering; medical diagnosis; biosensors; devices; lab-on-chip and organ-on-a-chip; biomedical instrumentation; smart sensing and predictive modelling; Industry-4.0-ehanced biomedical systems

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomaterials for Bone Repair and Regeneration

edited by

Jianhua Li

submission deadline 30 Apr 2025 | 11 articles | Viewed by 32731 | Submission Open

Keywords: biomaterials; bone scaffold; bone tissue engineering; osteogenesis; regenerative medicine; bone immunoregulation; antibacterial bone scaffold; bone implant; bone defect treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Polyhydroxyalkanoate (PHA) Production, 4th Edition

edited by

Martin Koller

submission deadline 30 Apr 2025 | 7 articles | Viewed by 21659 | Submission Open

(This special issue belongs to the Section Biochemical Engineering)

Smartphone- or Tablet-Based Technologies for Balance and Gait Rehabilitation

edited by

Beom-Chan Lee

submission deadline 30 Apr 2025 | 7 articles | Viewed by 17071 | Submission Open

Keywords: smartphone- or tablet-based technologies for balance and gait rehabilitation; exergame; diagnostic tools for balance and gait impairments; wearable sensors; telerehabilitation or telemonitoring; sensory biofeedback; aging or neurological disorders

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Tissue Engineering for Regenerative Dentistry

edited by

Shahram M. Ghanaati

and

Carlos Fernando Mourão

submission deadline 30 Apr 2025 | 8 articles | Viewed by 13967 | Submission Open

(This special issue belongs to the Section Regenerative Engineering)

Advances in Additive Manufacturing Technologies in the Clinical, Pharmaceutical and Biomedical Sectors

edited by

Karthik K. Tappa

and

Udayabhanu Jammalamadaka

submission deadline 30 Apr 2025 | 6 articles | Viewed by 13399 | Submission Open

Keywords: 3D printing; bioprinting; bioactive materials; bioink; anatomical models; surgical guides; patient-specific implants; 3D-printed drug delivery systems; 3D-printed biomedical devices

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Machine Learning and Deep Learning Applications in Healthcare

edited by

Jorge Mateo

and

Ana María Torres Aranda

submission deadline 30 Apr 2025 | 7 articles | Viewed by 10772 | Submission Open

Keywords: machine learning; deep learning; big-data enabled healthcare systems; biomedical diagnostic techniques; diagnostic imaging; medical decision making; digital pathology; digital radiology; artificial neural networks; artificial intelligence; smart health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Intelligent Health Management, Nursing and Rehabilitation Technology

edited by Ning Deng

submission deadline 30 Apr 2025 | 5 articles | Viewed by 10058 | Submission Open

Keywords: intelligent rehabilitation technology; health monitoring systems; machine learning in healthcare; intelligent nursing technology; data-driven health management

(This special issue belongs to the Section Biosignal Processing)

Biomedical Imaging and Data Analytics for Disease Diagnosis and Treatment, 2nd Edition

edited by

Cosimo Ieracitano

and

Xuejun Zhang

submission deadline 30 Apr 2025 | 13 articles | Viewed by 8942 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; biomedical engineering; medical image processing; data analytics

(This special issue belongs to the Section Biosignal Processing)

Advances in Physical Therapy and Rehabilitation

edited by

Alvaro N. Gurovich

submission deadline 30 Apr 2025 | 6 articles | Viewed by 8457 | Submission Open

Keywords: biomedical engineering; rehabilitation engineering; biomechanics; motor control; applied physiology; 3D printing; additive manufacture; imaging; ultrasound

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Innovations in Regenerative Therapy: Cell and Cell-Free Approaches

edited by

Prakash Gangadaran

submission deadline 30 Apr 2025 | 4 articles | Viewed by 7357 | Submission Open

Keywords: cell-based therapies; MSCs; exosome; extracellular vesicles; bio nanovesicles; wound; ischemia; hair growth; brain; degenerative diseases

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Biomedical Imaging and Biomedical Signal Processing

edited by Zvi Friedman

submission deadline 30 Apr 2025 | 4 articles | Viewed by 7238 | Submission Open

Keywords: artificial intelligence; biomedical imaging; biomedical signal processing; machine learning; deep learning; image segmentation; image classification; image retrieval; knowledge extraction

(This special issue belongs to the Section Biosignal Processing)

Adaptive Neurostimulation: Innovative Strategies for Stimulation

edited by

Luca Mesin

submission deadline 30 Apr 2025 | 3 articles | Viewed by 7025 | Submission Open

Keywords: neurostimulation; closed-loop stimulation; adaptive stimulation; sustained attention; working memory; meditation; relaxation; stress; mindfulness; epilepsy; psychiatric disorders; ADHD; transcranial direct current stimulation; transcranial alternating current stimulation; binaural beats; light pulse stimulation; EEG; ECG; pupillogram; breath monitoring; real time processing; EEG rhythms; complexity; entropy; heart rate variability

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Polymeric Biomaterials for Wound Healing Applications

edited by

Shangyou Yang

submission deadline 30 Apr 2025 | 3 articles | Viewed by 6650 | Submission Open

Keywords: polymeric biomaterials; wound healing; scaffolds; dressings; coatings; tissue regeneration; tissue engineering; biocompatibility; biodegradability; controlled release

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomechanics of Sports Injuries

edited by Man Soo Kim and Sue En Sohn

submission deadline 30 Apr 2025 | 4 articles | Viewed by 6273 | Submission Open

Keywords: sports; shoulder; knee; spine; hip; ankle; wrist; elbow; muscle; mechanics

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advances in Biomedical Analytics: Real-World Evidence, Digital Health, Robotics and Artificial Intelligence

edited by

Kelly H. Zou

, Susan Halabi, Aaron Galaznik and Kiyoyuki Chinzei

submission deadline 30 Apr 2025 | 2 articles | Viewed by 6035 | Submission Open

Keywords: real-world data; real-world evidence; big data; randomized controlled trials; patient-reported outcomes; digital innovation; digital health; robotics; medical devices; artificial intelligence; machine learning; deep learning

(This special issue belongs to the Section Biosignal Processing)

10th Anniversary of Bioengineering: Biosignal Processing

edited by

Andrea Cataldo

Francesco Amato

and Raissa Schiavoni

submission deadline 30 Apr 2025 | 5 articles | Viewed by 5608 | Submission Open

Keywords: biosignal processing; signal analysis; biomedical devices; medical diagnostics; biomedical imaging; biomedical engineering; health monitoring; wearable systems; image processing and visualization; biosensor technology; biosensors; lab-on-chip and organ-on-a-chip instrumentation; smart sensing and predictive modeling; 4.0-ehanced biomedical systems

(This special issue belongs to the Section Biosignal Processing)

Fundamentals of Orthopaedic Biomechanics: Implants, AI, and Innovation in Surgery

edited by Farid Amirouche

submission deadline 30 Apr 2025 | 3 articles | Viewed by 5160 | Submission Open

Keywords: orthopedics; biomechanics; implants; shoulder; knee; hip; hand and motion analysis; AI; augmented reality; ortho innovation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Assessment of Medical Devices

edited by Andrew Robert Beadling, Michael Bryant and Richard M. Hall

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4369 | Submission Open

Keywords: medical devices; preclinical assessment; biomaterials; bioengineering; regulatory science; digital twins

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Multimodal Imaging Methodologies and Virtual/Augmented Reality for Biomedical Applications

edited by

Vera Gramigna

and Arrigo Palumbo

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4337 | Submission Open

Keywords: multimodal imaging; magnetic resonance imaging (MRI); computerized tomography (CT); positron emission tomography (PET); single-photon emission computed tomography (SPECT); functional near infrared spectroscopy (fNIRS); virtual; augmented; and mixed reality; biomedicine; human– robot interaction; technology in healthcare

(This special issue belongs to the Section Biosignal Processing)

Application of Bioengineering to Implant Dentistry

edited by Rolf Ewers

submission deadline 30 Apr 2025 | 2 articles | Viewed by 4156 | Submission Open

Keywords: bioengineering; dental implantology; implant dentistry; dental biomaterials; surface modifications; biomechanics of implant integration; tissue engineering; biocompatibility; implant-associated infections

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

ML and AI for Augmented Biosensing Applications

edited by

Rossana Madrid

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3950 | Submission Open

(This special issue belongs to the Section Biosignal Processing)

Natural Peptides/Proteins and Their Applications in Bioengineering

edited by

Satish Rojekar

and Anusha Rani Pallapati

submission deadline 30 Apr 2025 | 1 articles | Viewed by 3767 | Submission Open

Keywords: peptide design; protein engineering; biomaterial fabrication; drug delivery systems; tissue regeneration; bioengineering; biomaterials; biomedical application

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence in Biomedical Diagnosis and Prognosis: Second Edition

edited by

Tae-Seong Kim

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3666 | Submission Open

Keywords: medical diagnosis; medical prognosis; medical AI; machine learning; deep learning; pervasive AI medical systems

(This special issue belongs to the Section Biosignal Processing)

Dental Implant Reconstruction and Biomechanical Evaluation, 2nd Edition

edited by

Bongju Kim

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3224 | Submission Open

Keywords: dental materials; dental implants; dental prosthesis; implant-supported prosthesis; FEA; FEM; computational modelling; biomechanical characterization

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Computer-Aided Diagnosis for Biomedical Engineering

edited by

Brij Gupta

Nadia Nedjah

and

Kwok Tai Chui

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2961 | Submission Open

Keywords: computer-aided diagnosis; biomedical engineering; secure biomedical; machine learning; deep learning; image processing; medical imaging; clinical decision support systems

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence for Skin Diseases Classification

edited by Alessandra Cartocci and Linda Tognetti

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2932 | Submission Open

Keywords: artificial intelligence; dermatology; skin diseases classification; machine learning; deep learning; computer vision; skin lesion detection; healthcare

(This special issue belongs to the Section Biosignal Processing)

Integrating Novel Therapeutics and Personalized Medicine into Osteoarthritis Treatment: Advancements in Cartilage Regeneration and Joint Preservation

edited by

Antonia Sun

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2868 | Submission Open

Keywords: osteoarthritis; cartilage regeneration; personalized medicine; tissue engineering; stem cell therapy; gene therapy; biomaterials; molecular therapeutics; regenerative medicine; biomechanics; translational research; advanced imaging techniques; patient-specific therapies; inflammation modulation; bioinformatics; computational modeling

(This special issue belongs to the Section Regenerative Engineering)

Machine Learning Methods for Biomedical Imaging

edited by Lei Qiu, Yibo Xie and Suk Whan Yoon

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2468 | Submission Open

Keywords: AI; machine learning; deep learning; biomedical image analysis

(This special issue belongs to the Section Biosignal Processing)

Waste-to-Resource: Microbial-Driven Processes for Gaseous, Liquid and Solid Wastes Valorization

edited by Valeria Agostino, Annalisa Abdel Azim and Nicolò S. Vasile

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2255 | Submission Open

Keywords: waste-to-resource; CO2 valorization; industrial waste streams valorization; bio-based manufacturing; acetogens; microalgae; methanogens; methanotrophs; fermentation

(This special issue belongs to the Section Biochemical Engineering)

Research Progress in Stem Cells and Regenerative Medicine

edited by

Naoki Yamamoto

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2081 | Submission Open

Keywords: regenerative medicine; cancer therapy; culture method; drug screening; alternative methods of animal experiment

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Development of Bioelectrochemical Systems for Environmental Engineering

edited by

Shiue-Lin Li

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1626 | Submission Open

Keywords: bioelectrochemical systems; microbial fuel cells; bioelectrosynthesis; high-added value chemicals; environmental engineering

(This special issue belongs to the Section Biochemical Engineering)

Connective Tissue Structure and Function in Normal, Pathological and Aging Skin

edited by Agata Jabłońska-Trypuć

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1581 | Submission Open

Keywords: connective tissue; skin; fibroblasts; collagen; ECM; aging

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Engineering Cells for Immunotherapy

edited by Yun Chang

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1547 | Submission Open

Keywords: cell engineering; CAR T cells; immunotherapy; genetically modified immune cells; tumor targeting; synthetic biology; biomaterials for cell therapy; gene editing for immunotherapy; delivery systems; molecular immunoengineering; preclinical and clinical immunotherapies

(This special issue belongs to the Section Regenerative Engineering)

Advancements in Tissue-Engineered Muscle

edited by Filiz Ates

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1323 | Submission Open

Keywords: skeletal muscle; tissue engineering; biomaterial scaffolds; contractile force; myoblasts; satellite cells; stem cells; volumetric muscle loss; muscle regeneration; myogenic differentiation; vascularization; organ-on-chip; nanofibers; 3D printing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Biomaterials in Dental Medicine

edited by

Alfredo De Rosa

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1171 | Submission Open

Keywords: biomaterials; dental medicine; dental implants; orthodontics; oral health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

New Technique for Endoscopic Diagnosis in Biomedical Engineering

edited by Changseok Bang

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1031 | Submission Open

Keywords: endoscopic diagnosis; gastroenterology; novel technique; precision medicine; minimally invasive; patient- friendly; state-of-the-art technology; gastrointestinal disorders; diagnostic accuracy; research innovation

(This special issue belongs to the Section Biosignal Processing)

Advancements in Computational Modelling and Imaging Techniques for Personalised Treatment of Aortic Aneurysms

edited by

José Xavier

and

Simona Celi

submission deadline 30 Apr 2025 | 1 articles | Viewed by 1002 | Submission Open

Keywords: cardiovascular diseases; silico modelling; computational fluid– structure interaction frameworks; advanced imaging techniques

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Cell Mechanobiology in Health and Disease

edited by Sangyoon Han

submission deadline 30 Apr 2025 | Viewed by 648 | Submission Open

Keywords: mechanobiology; fibroblasts; immune cells; stem cells; cancer cells; connective tissue disorder; extracellular matrix; shear stress sensing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Materials and Methods for Genetic and Cell-Based Therapy for Ocular Tissue

edited by Jesse Sengillo

submission deadline 30 Apr 2025 | Viewed by 602 | Submission Open

Keywords: retinal injury; retinal repair; biomaterials; surgical techniques; drug delivery systems; imaging modalities; stem cell therapy; gene therapy; regenerative medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Comprehensive Insights into Mechanical Circulatory Support in End-Stage Heart Failure

edited by Claudia Maria Loardi, Emmanuelle Vermes and Marco Zanobini

submission deadline 30 Apr 2025 | Viewed by 556 | Submission Open

Keywords: end-stage heart failure; cardiovascular engineering; cardiovascular technology; biomedical imaging; computational modeling; biventricular assistance; total artificial heart; left-ventricular assist device

(This special issue belongs to the Section Regenerative Engineering)

Advanced Systems in Radiotherapy

edited by

Rosario Megna

and Marcello Serra

submission deadline 30 Apr 2025 | 1 articles | Viewed by 523 | Submission Open

Keywords: innovative techniques; cancer treatment; radiation therapy

(This special issue belongs to the Section Biosignal Processing)

AI-Enhanced Biomechanics and Rehabilitation Engineering

edited by

Tarun Goswami

Anmar Salih

and

Farah Hamandi

submission deadline 30 Apr 2025 | Viewed by 439 | Submission Open

Keywords: artificial intelligence; biomechanics; rehabilitation engineering; machine learning; predictive modeling; prosthetic; gait analysis; personalized healthcare; biomechanical data analysis; injury prevention; fatigue detection; custom orthopedic solutions; biomechanical simulation; biomechanical performance; AI in biomechanical research

(This special issue belongs to the Section Biosignal Processing)

Microalgae Biotechnology and Microbiology: Prospects and Applications

edited by Dora Allegra Carbone and Michael Melkonian

submission deadline 30 Apr 2025 | 1 articles | Viewed by 309 | Submission Open

Keywords: microalgae; bacteria; photobioreactor; bioengineering; biomass; wastewater; compounds

(This special issue belongs to the Section Biochemical Engineering)

Microfluidic Devices for Biomedical Engineering

edited by Therese W. Herling

submission deadline 30 Apr 2025 | Viewed by 277 | Submission Open

Keywords: microfluidics; lab-on-a-chip; organ-on-a-chip; diagnostics; microfabrication; biomedical analysis; biomarker detection; biomolecular analysis and characterization; biomolecular separation; microdroplets; microreactors; detection and optics; single-cell analysis; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomaterials for Oral Health Maintenance: A Translational Approach

edited by

Andrea Butera

and Cinzia Casu

submission deadline 30 Apr 2025 | Viewed by 246 | Submission Open

Keywords: biomaterial; oral health; translational medicine; dental care; caries; periodontitis; peri-implantitis; oral medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Design and Control Innovations in Prosthetic Hands: From Appearance to Advanced Functionality

edited by

Wenjun (Chris) Zhang

submission deadline 30 Apr 2025 | Viewed by 223 | Submission Open

Keywords: prosthetic hands; biomechanics; neural control systems; soft prosthetics; advanced materials; user-centered design; 3D printing in prosthetics; wireless control systems; mind-controlled prosthetics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Electrical Stimulation Systems for Cardiac Tissue Engineering

edited by Johannes Muller

submission deadline 30 Apr 2025 | Viewed by 178 | Submission Open

Keywords: electrical stimulation; cardiac tissue engineering; myocardial regeneration; biomaterial scaffolds; electrode design; tissue maturation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Emerging Trends in Materials for Advanced Biosensing and Biomedical Applications

edited by Xuan Luo

submission deadline 30 Apr 2025 | Viewed by 173 | Submission Open

Keywords: biosensing; biomedical applications; novel materials; nanomaterials; biocompatibility; sustainability

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Drug Delivery in Cancer Treatment

edited by

Chang Yang

submission deadline 30 Apr 2025 | Viewed by 165 | Submission Open

Keywords: cancer; drug delivery; nanotechnology; targeted therapy; combination therapy; biomaterials

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

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