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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Bone Regeneration with Multipotential Stromal Cells and Bioactive Materials

edited by

Elena A. Jones

Jehan J. El-Jawhari

and

Dimitrios Kouroupis

submission deadline 30 Jun 2025 | 11 articles | Viewed by 30135 | Submission Open

Keywords: multipotential stromal/mesenchymal stem cells (MSCs); bone regeneration; cell engineering; activated matrices; sensors and imaging; scaffolds and biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Recent Advances in Machine Learning and Explainable Artificial Intelligence in Biomedical Data Mining, and Disease Diagnosis Frameworks

edited by

Amad Zafar

submission deadline 30 Jun 2025 | 9 articles | Viewed by 16127 | Submission Open

Keywords: EEG; fNIRS; MRI; X-rays; biomedical signal and image processing; machine learning; explainable artificial intelligence; biomedical data mining; computer-aided diagnosis; brain– computer interfaces; healthcare

(This special issue belongs to the Section Biosignal Processing)

Smart Engineering: Integrating Artificial Intelligence and Bioengineering

edited by

Daniele Giansanti

submission deadline 30 Jun 2025 | 3 articles | Viewed by 12627 | Submission Open

Keywords: bioengineering; smart engineering; artificial Intelligence; care robots; wearable devices; medical devices; mobile health; biomedical instrumentation; deep learning; machine learning; IoT

Biomechanics of Orthopaedic Rehabilitation

edited by Songning Zhang

submission deadline 30 Jun 2025 | 9 articles | Viewed by 11902 | Submission Open

Keywords: orthopedic; rehabilitation; joint arthroplasty; biomechanics; osteoarthritis; rehabilitation; pain; muscle; gait; cycling; muscle activation inhibition

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Applications of Bioprinting in Biomedicine

edited by

Chunya Wu

and

Lihua Lu

submission deadline 30 Jun 2025 | 4 articles | Viewed by 10853 | Submission Open

Keywords: bioprinting technology; bioink; bioprinting processes; bioprinter

(This special issue belongs to the Section Regenerative Engineering)

Spine Biomechanics

edited by Christian Liebsch

submission deadline 30 Jun 2025 | 11 articles | Viewed by 9831 | Submission Open

Keywords: biomechanics; spine; intervertebral disc; experiment; modeling; in vivo; in vitro; in silico

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Robotic Assisted Rehabilitation and Therapy

edited by

Carlos A. Jara

and

Andres Ubeda

submission deadline 30 Jun 2025 | 4 articles | Viewed by 8403 | Submission Open

Keywords: assistive rehabilitation robotics; electromyography (EMG); electroencephalography (EEG); computer vision and AI algorithms; exoskeletons or exosuits for assistance/rehabilitation; collaborative manipulators for assistive rehabilitation therapy

(This special issue belongs to the Section Biosignal Processing)

Advanced Biomaterials, Coatings, and Techniques: Applications in Medicine

edited by Yong Hou

submission deadline 30 Jun 2025 | 5 articles | Viewed by 8315 | Submission Open

Keywords: biomaterials; coatings; advanced techniques; medical devices; implants; tissue engineering; biocompatibility; 3D printing; nanotechnology; surface modification

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Regenerative Technologies in Plastic and Reconstructive Surgery

edited by Alanna M. Rebecca,

Joris A. van Dongen

and

Steven Paul Nistico

submission deadline 30 Jun 2025 | 4 articles | Viewed by 6618 | Submission Open

Keywords: plastic surgery; reconstructive surgery; tissue engineering; burn reconstruction; biomaterials; 3D bioprinting; regenerative medicine

(This special issue belongs to the Section Regenerative Engineering)

Advanced Technology for Implant Polymers in Orthopaedics, Spine, and Trauma

edited by Steven M. Kurtz, Hannah Spece,

Pierangiola Bracco

and

Francisco Javier Medel

submission deadline 30 Jun 2025 | 3 articles | Viewed by 5278 | Submission Open

Keywords: UHMWPE; highly crosslinked UHMWPE; HXLPE; PEEK; PEKK; PAEK; additive manufacturing; AM; 3D printing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomechanics of Physical Exercise

edited by

Andrea Biscarini

submission deadline 30 Jun 2025 | 5 articles | Viewed by 5093 | Submission Open

Keywords: biomechanics; kinematics; kinetics; muscle activation; joint loads; proprioception; postural control and balance; neuromotor control; human movement; physical exercise; athletic training; athletic performance; sport; injury prevention; rehabilitation; exercise equipment; equipment design; ergonomics; motion analysis; force plates; electromyography; EMG; musculoskeletal modelling; simulation; sensors; imaging; magnetic resonance; MRI; artificial intelligence; robotics; new technologies

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Cutting-Edge Applications of Machine and Deep Learning in Biomedical Signal and Image Processing

edited by

Pedro Miguel Rodrigues

, Bruno Bispo and Joaquim Celestino

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4479 | Submission Open

Keywords: biosignal analysis; medical image analysis; machine learning; deep learning; wearable bio-technology

(This special issue belongs to the Section Biosignal Processing)

Machine Learning-Aided Medical Image Analysis

edited by

Amirreza Mahbod

and Ramona Woitek

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4021 | Submission Open

Keywords: artificial intelligence; deep learning; machine learning; medical image analysis; medical imaging

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence Revolution in Biomedical Image and Signal Processing: Innovations and Applications

edited by

Shih-Lun Chen

Liang-Hung Wang

and Tsung-Yi Chen

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3657 | Submission Open

Keywords: artificial intelligence techniques for biomedical signal and image processing; medical image processing; deep learning; AI-based diagnostic imaging; multimodal image fusion; early disease detection; image-guided surgery

(This special issue belongs to the Section Biosignal Processing)

Advancements in Biocompatible Materials for Implantable Medical Devices

edited by

Tarun Goswami

and

Farah Hamandi

submission deadline 30 Jun 2025 | 1 articles | Viewed by 3645 | Submission Open

Keywords: biomaterials; clinical engineering; biomedical devices; cardiovascular engineering; biomedical instrumentation; biomechanical engineering; biomedical modeling; biomedical technology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Engineering Technologies in Orthopaedic Research

edited by Guoan Li,

Tsung-Yuan Tsai

and Shaobai Wang

submission deadline 30 Jun 2025 | 5 articles | Viewed by 3380 | Submission Open

Keywords: orthopaedic biomechanics; kinematics; articular joints; knee; hip; ankle; shoulder; spine; MRI; CT; robotic testing system; bi-plane imaging; FEA; computation modeling

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Anaerobic Digestion Advances in Biomass and Waste Treatment

edited by

Tina Kegl

and Breda Kegl

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2293 | Submission Open

Keywords: waste management; biomass and waste pre-treatments; anaerobic digestion; modeling and optimization; biogas plants; biogas production; digestate treatment; microbial fuel cells; electricity production

(This special issue belongs to the Section Biochemical Engineering)

Antennas for Biomedical Applications

edited by

Pedro Pinho

and

Daniel Filipe Albuquerque

submission deadline 30 Jun 2025 | 1 articles | Viewed by 2071 | Submission Open

Keywords: biomedical applications; wireless communication; remote sensing; monitoring; biocompatible; efficiency; low power; implantable antennas; wearable antennas; health tracking wireless power transfer

(This special issue belongs to the Section Biosignal Processing)

Intelligent Systems for Human Action Recognition

edited by

Mondher Bouazizi

, Yue Yin and Tomoaki Ohtsuki

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1948 | Submission Open

Keywords: wearable sensors; IoT devices; action recognition; computer vision; video analysis; image processing; pattern recognition; human– robot interaction; healthcare; biomedical sensing; biosignal processing; signal processing; activity detection; deep learning; AI

(This special issue belongs to the Section Biosignal Processing)

Advances on Cancer-on-Chip Models

edited by

Mohammad Kohandel

and Nafiseh Moghimi

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1938 | Submission Open

Keywords: cancer-on-chip models; personalized medicine; real-time monitoring; 3D cell cultures; tumour microenvironment; mathematical and computational modelling

(This special issue belongs to the Section Regenerative Engineering)

Personalized Cardiovascular Medicine: Latest Devices, Surgical Techniques, and Tissue Engineering Strategies—Second Edition

edited by

David Santer

Karl H. Schneider

and

George Truskey

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1763 | Submission Open

Keywords: cardiovascular medicine; 3D bioprinting cardiac patch; novel scaffold design; hybrid procedures; minimally invasive cardiac surgery; interventional valve replacement; aortic surgery; aortic interventions; valve procedures; devices

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering Neural Motor Control: From Mechanisms to Neural Interfaces

edited by Eizo Miyashita and Yuki Ueyama

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1732 | Submission Open

Keywords: systems neuroscience; computational neuroscience; motor control; motor learning; motor dysfunction; rehabilitation; neuromodulation; human argumentation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Cell Bioprocess Engineering: Basic Fundamentals and Applications

edited by

Jeffrey J. Chalmers

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1617 | Submission Open

Keywords: cell culture; bioprocess engineering; cell separation; biologics; cellular therapies

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

New Sights of Mathematical Modeling in Biomedicine: Updates and Direction

edited by

Kayode Oshinubi

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1541 | Submission Open

Keywords: mathematical modeling; machine learning; predictive modeling; data modeling; biological systems

(This special issue belongs to the Section Biosignal Processing)

Smart Applications and Technology for Cardiovascular Disease Management

edited by Alexander Samol and Sven Kaese

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1343 | Submission Open

Keywords: cardiovascular disease; smart applications; technology; wearable devices; artificial intelligence; telemedicine; virtual reality

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Ophthalmic Engineering (3rd Edition)

edited by

Xiaofei Wang

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1254 | Submission Open

Keywords: ophthalmology; biomechanics; eye; medical imaging; optical coherence tomography; artificial intelligence; deep learning; virtual reality; medical device; finite element method; inverse analysis

(This special issue belongs to the Section Regenerative Engineering)

Transforming Healthcare with Large Language Models: Innovations, Challenges, and Future Directions

edited by

Essam A. Rashed

, Walayat Hussain and

Ghada Khoriba

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1110 | Submission Open

Keywords: large language models (LLMs); large vision models (LVMs); summarization of medical data; medical report generation; medical chatbots; healthcare data analysis; medical imaging; trustworthy AI; diagnosis

Numerical Simulation and AI in Biological Systems

edited by

Claudio De Lazzari

submission deadline 30 Jun 2025 | 1 articles | Viewed by 799 | Submission Open

Keywords: numerical model; software simulator; AI tools; e-learning; 0D; 1D; and 3D model; clinical environment; hybrid model; athletic performance; biomechanics in athletics; movement analysis; computer assist surgery

3D Cell Culture Systems: Current Technologies and Applications

edited by

Peggy Stock

submission deadline 30 Jun 2025 | 1 articles | Viewed by 676 | Submission Open

Keywords: 3D cell culture; tissue engineering; biomaterials; drug discovery; cancer research; regenerative medicine; scaffold technology; high-throughput screening; organoids; in vitro models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Nerve Regeneration

edited by Luca Cicero,

Claudia Giampietri

and

Munmun Chattopadhyay

submission deadline 30 Jun 2025 | 1 articles | Viewed by 424 | Submission Open

Keywords: nerve regeneration; neuroengineering; biomaterials; stem cells; neuroprosthetics; biomedical devices

(This special issue belongs to the Section Regenerative Engineering)

Advances in Additive Biofabrication: From Techniques to Emerging Applications

edited by

Yageng Li

, Nazlı Tümer and Pedro J. Díaz-Payno

submission deadline 30 Jun 2025 | Viewed by 406 | Submission Open

Keywords: additive manufacturing; biofabrication; bioprinting; bioceramic printing; metal printing; tissue engineering; biomedical engineering; regenerative medicine

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Recent Progress of Autophagy in Cardiovascular Disease

edited by Lu Zhang, Liang Hong and

George Truskey

submission deadline 30 Jun 2025 | Viewed by 375 | Submission Open

Keywords: autophagy; gene edit; myocardial infarction; heart failure; atherosclerosis; cardiovascular tissue engineering

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Biomedical Image Processing and Sensing Applications

edited by

Tariq Mahmood Khan

submission deadline 30 Jun 2025 | Viewed by 361 | Submission Open

Keywords: biomedical image processing; biomedical sensing; medical imaging modalities; diagnostic tools; healthcare innovation; image enhancement algorithms; physiological data monitoring; disease diagnosis; medical device development; healthcare technology

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Healthy Aging

edited by Arkers Wong, Jed Montayre and Justina Liu

submission deadline 30 Jun 2025 | Viewed by 343 | Submission Open

Keywords: machine learning; ecological momentary assessment; wearable; gerontechnology; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Design and Fabrication of Biosensors for Biomedical Applications

edited by

Zuan-Tao Lin

submission deadline 30 Jun 2025 | Viewed by 337 | Submission Open

Keywords: biosensors; point-of-care; wearable sensor; ultrasensitive detection; biomarkers; multiplex detection; disease diagnostics; early diagnostics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Neuroimaging Techniques for Central Autonomic System: Methodologies and Applications

edited by Antonio Ferretti and Mauro Gianni Perrucci

submission deadline 30 Jun 2025 | Viewed by 283 | Submission Open

Keywords: integration of EEG; fMRI; fNIRS; or other neuroimaging modalities; fMRI preprocessing; autonomic system; central autonomic network; physiological noise; brainstem; epilepsy; sudep; valsalva maneuver; functional connectivity; integration of neuroimaging and extended-reality protocols

(This special issue belongs to the Section Biosignal Processing)

Trends in Vascular Tissue Engineering

edited by

Michalis P. Katsimpoulas

and Yuncheng Du

submission deadline 30 Jun 2025 | Viewed by 262 | Submission Open

Keywords: cardiovascular disease; 3D bioprinting; vascular grafts; stem cells; scaffolds

(This special issue belongs to the Section Regenerative Engineering)

Engineered Extracellular Vesicles for Tissue Regeneration

edited by

Mikko J. Lammi

submission deadline 30 Jun 2025 | Viewed by 243 | Submission Open

Keywords: extracellular vesicles; tissue regeneration; bioengineering; nanotechnology; stem cells; cell therapy; drug delivery; biomaterials; regenerative medicine; therapeutic applications

(This special issue belongs to the Section Regenerative Engineering)

Printable Biomaterials from Tissue Engineering to Orthopedics: Fabrication, Mechanical Performance, and Biological Behavior

edited by

Gianpaolo Serino

and

Gulden Camci-Unal

submission deadline 30 Jun 2025 | Viewed by 190 | Submission Open

Keywords: advanced printable biomaterials; biocompatibility; bioactivity; mechanical properties; physical and chemical properties

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Soft and Flexible Sensors for Biomedical Applications

edited by Martina Maselli and Parisa Pour Shahid Saeed Abadi

submission deadline 30 Jun 2025 | Viewed by 167 | Submission Open

Keywords: stretchable electronics; flexible sensors; biomedical applications; wearable devices; conformable materials; health monitoring

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Dental Pulp Stem Cells in Clinical Application: Present and Future Perspectives

edited by

Ciro Gargiulo Isacco

submission deadline 30 Jun 2025 | Viewed by 166 | Submission Open

Keywords: dental pulp stem cells; cell injections; modified cells; cell sheets; cell spheroids; regeneration; damaged tissues; immunomodulation

(This special issue belongs to the Section Regenerative Engineering)

Biologically Active Constituents and Their Applications for Skin Regeneration and Repair

edited by

Qi Xiang

and Lihua Li

submission deadline 15 Jul 2025 | 4 articles | Viewed by 8095 | Submission Open

Keywords: active constituents; protein; cell factory; biomaterials; drug carrier; drug delivery; bacterial derivatives; skin regeneration; skin repair

(This special issue belongs to the Section Biochemical Engineering)

Design and Synthesis of Functional Deuterated Biomaterials

edited by Nageshwar R. Yepuri

submission deadline 20 Jul 2025 | 1 articles | Viewed by 1054 | Submission Open

Keywords: deuterated lipids; deuterated phospholipids; lipid nano particle; lipid nano discs; deuterated fatty acids; deuterated amino acids

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Emerging Artificial Intelligence Trends for Predictive Analytics and Personalized Healthcare

edited by

Josu Maiora

Maria Begoña Sanz Echevarría

and

Manuel Graña

submission deadline 20 Jul 2025 | Viewed by 219 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; predictive analytics; wearable sensors; medical devices; medical image analysis

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Dentistry: Innovations, Applications, and Future Perspectives

edited by

Hang Nga Mai

and

Tim Joda

submission deadline 31 Jul 2025 | 10 articles | Viewed by 32093 | Submission Open

Keywords: artificial intelligence; big data in dentistry; explainable AI in dental diagnostics; blockchain in dental data security; natural language processing in dental records; robotics in dentistry; smart dental devices; AI in clinical decision support; automation in dentistry; AI-based diagnostic imaging; AI-supported treatment planning

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Optical Imaging and Machine Learning in Biomedicine

edited by

Daniel L. Farkas

submission deadline 31 Jul 2025 | 10 articles | Viewed by 17014 | Submission Open

Keywords: optical imaging; machine learning; biomedicine; bioengineering; biophotonics; translational research; interdisciplinary

(This special issue belongs to the Section Biosignal Processing)

Engineering Biodegradable-Implant Materials, 2nd Edition

edited by

Hamdy Ibrahim

submission deadline 31 Jul 2025 | 5 articles | Viewed by 11014 | Submission Open

(This special issue belongs to the Section Regenerative Engineering)

Biomechanics Studies in Ophthalmology

edited by Joseph L. Demer

submission deadline 31 Jul 2025 | 8 articles | Viewed by 10277 | Submission Open

Keywords: eye movements; finite element modeling; glaucoma; myopia; ocular biomechanics; ocular trauma; ocular viscoelasticity; optic neuropathy; strabismus

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Musculoskeletal Function in Health and Disease

edited by Adrian Paul Harrison and Else Marie Bartels

submission deadline 31 Jul 2025 | 3 articles | Viewed by 6246 | Submission Open

Keywords: musculoskeletal disorders; muscle injury; pre-habilitation and rehabilitation; healthcare; wearable technology; quality of life; sport science; sport medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Intelligent Wearable and Implantable Devices for Biomedical Applications

edited by Milad Zamani and

Dante Mantini

submission deadline 31 Jul 2025 | 3 articles | Viewed by 5942 | Submission Open

Keywords: bio-inspired and neuromorphic computation; spiking neural networks; biosensor devices and interface circuits; bioelectronics; biosensors; biotelemetry

(This special issue belongs to the Section Biosignal Processing)

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