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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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AI in OCT (Optical Coherence Tomography) Image Analysis

edited by

Juhwan Lee

and Kiran Kumar Vupparaboina

submission deadline 30 Sep 2025 | 9 articles | Viewed by 18244 | Submission Open

Keywords: retinal imaging; dental imaging; intravascular imaging; optical coherence tomography; machine learning; deep learning; advanced image processing

(This special issue belongs to the Section Biosignal Processing)

Advancing Healthcare: Harnessing AI for Diagnostic and Therapeutic Innovations

edited by Wei-Chang Yeh

submission deadline 30 Sep 2025 | 3 articles | Viewed by 10850 | Submission Open

Keywords: artificial intelligence; personalized healthcare; medicine; bioengineering; machine learning

(This special issue belongs to the Section Biosignal Processing)

Tailored Peptide Modifications for Advanced Infection Control Strategies

edited by Piyush Baindara, Ravinder Kumar and

Santi Mandal

submission deadline 30 Sep 2025 | 3 articles | Viewed by 9636 | Submission Open

Keywords: peptide-based vaccines; drug resistance; protein engineering; infectious diseases; antibacterial; antifungal; antiviral; immunotherapies; therapeutics

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Biomaterials and Technology for Tumor Engineering

edited by

Girdhari Rijal

and

Narayan Bhattarai

submission deadline 30 Sep 2025 | 1 articles | Viewed by 8906 | Submission Open

Keywords: three-dimensional tumor models; xenograft tumors; cancer cell signatures; H-scan ultrasound; in vivo imaging systems; dye-tagged cell technologies; scaffolds; tumoroids; spheroids; anticancer drugs

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Computational Genomics for Disease Prediction

edited by

Pietro Pinoli

submission deadline 30 Sep 2025 | 5 articles | Viewed by 8776 | Submission Open

Keywords: computational genomics; disease prediction; genetic markers; high-throughput sequencing; machine learning; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomaterials for Cartilage and Bone Tissue Engineering: Second Edition

edited by

Francesca Scalera

submission deadline 30 Sep 2025 | 5 articles | Viewed by 7323 | Submission Open

Keywords: cartilage; bone; scaffolds; stem cells; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Periodontics and Implant Dentistry

edited by

Sergio Alexandre Gehrke

submission deadline 30 Sep 2025 | 3 articles | Viewed by 6945 | Submission Open

Keywords: periodontics; implantology; technological advances; periodontal health; dental implants; digital planning; guided tissue regeneration; laser therapy; biomaterials; minimally invasive therapies; 3D printing; artificial intelligence; cone beam computed tomography (CBCT); biomodulation; peri-implantitis; tissue engineering; sustainability in dentistry; stem cells; bioprinting; oral rehabilitation

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Strategies for Ophthalmic Diseases

edited by

Jae Yong Kim

submission deadline 30 Sep 2025 | 3 articles | Viewed by 5613 | Submission Open

Keywords: ophthalmic diseases; imaging technology; artificial intelligence; retinal regeneration; corneal implants; drug delivery

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Computational Modeling in Biomedical Image and Signal Processing—2nd Edition

edited by Xuxin Chen and

Bin Zheng

submission deadline 30 Sep 2025 | 3 articles | Viewed by 5498 | Submission Open

Keywords: computational modeling; quantitative disease markers; medical image processing; image segmentation; biosignal testing; biosignal processes; feature selection; deep learning; computer-aided diagnosis; data standardization; synthetic data generation

(This special issue belongs to the Section Biosignal Processing)

Breast Cancer: From Precision Medicine to Diagnostics

edited by Kosuke Kawaguchi

submission deadline 30 Sep 2025 | 4 articles | Viewed by 5442 | Submission Open

Keywords: breast cancer; precision medicine; diagnostics; novel treatment options; personalized treatment; tumor microenvironment; breast imaging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Development of Bioelectrochemical Systems for Environmental Engineering

edited by

Shiue-Lin Li

submission deadline 30 Sep 2025 | 3 articles | Viewed by 5296 | Submission Open

Keywords: bioelectrochemical systems; microbial fuel cells; bioelectrosynthesis; high-added value chemicals; environmental engineering

(This special issue belongs to the Section Biochemical Engineering)

Dental Implant Reconstruction and Biomechanical Evaluation, 2nd Edition

edited by

Bongju Kim

submission deadline 30 Sep 2025 | 2 articles | Viewed by 4517 | Submission Open

Keywords: dental materials; dental implants; dental prosthesis; implant-supported prosthesis; FEA; FEM; computational modelling; biomechanical characterization

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence for Biomedical Signal Processing, 2nd Edition

edited by

Verónica Barroso-García

and

Fernando Vaquerizo-Villar

submission deadline 30 Sep 2025 | 3 articles | Viewed by 3842 | Submission Open

Keywords: aid diagnosis; automatic diagnosis; biomedical signals; biomedical signal processing; deep learning; diseases; explainable artificial intelligence; machine learning; physiological time series; predictive models

(This special issue belongs to the Section Biosignal Processing)

Musculoskeletal Bioengineering: Imaging and Computational Modeling in Biomechanics

edited by Geoffrey Handsfield

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3669 | Submission Open

Keywords: musculoskeletal bioengineering; biomechanics; imaging; computational modeling; musculoskeletal system; biomedical engineering; orthopedics

(This special issue belongs to the Section Biosignal Processing)

Biomaterials for the Repair and Regeneration of Musculoskeletal Tissue

edited by Christopher Bibbo

submission deadline 30 Sep 2025 | 1 articles | Viewed by 3114 | Submission Open

Keywords: musculoskeletal; soft tissue; bone; cartilage; nerve; regenerative medicine; reconstructive surgery

(This special issue belongs to the Section Regenerative Engineering)

Wearable, Flexible, and Integrated Microfluidic-Based Biosensors for Point-of-Care Testing Applications

edited by Madhusudan B. Kulkarni

submission deadline 30 Sep 2025 | 1 articles | Viewed by 3041 | Submission Open

Keywords: biomedical electronic devices; health-monitoring wearables; implantable sensors; bioelectronic medicine; personalized healthcare

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Microalgae Biotechnology and Microbiology: Prospects and Applications

edited by Dora Allegra Carbone and Michael Melkonian

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2315 | Submission Open

Keywords: microalgae; bacteria; photobioreactor; bioengineering; biomass; wastewater; compounds

(This special issue belongs to the Section Biochemical Engineering)

Hydrogels for Biomedical Applications, 2nd Edition

edited by

Pallabi Pal

submission deadline 30 Sep 2025 | 1 articles | Viewed by 2025 | Submission Open

Keywords: drug delivery systems; surface modified biomaterials; self-healing hydrogels; thermoresponsive hydrogels; injectable hydrogels; tissue regeneration; 3D printing; bioactive hydrogels

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Drug Delivery in Cancer Treatment

edited by

Chang Yang

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1495 | Submission Open

Keywords: cancer; drug delivery; nanotechnology; targeted therapy; combination therapy; biomaterials

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Innovations in Hollow Viscera Imaging: Engineering Breakthroughs and Clinical Translation

edited by

and

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1209 | Submission Open

Keywords: hollow viscera imaging; bioengineered diagnostics; AI in endoscopy; minimally invasive devices; functional luminal mapping; smart stents & microsensors; computational biomechanics; clinical translation

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence and Wearable Biosensors for Precision Medicine: Integrating Technology

edited by

Matteo Frigerio

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1115 | Submission Open

Keywords: healthcare; gynecology; pelvic floor medicine; pelvic floor rehabilitation; pelvic floor training; laparoscopy; pelvic organ prolapse; urinary incontinence; anal incontinence; overactive bladder; ultrasound; urodynamics; urogynecology; new technologies; pelvic pain; laser; radiofrequency; magnetic stimulation; functional electrical stimulation; biofeedback; vaginal rejuvenation; electronic bladder diaries; sacral neuromodulation; women’ s health

(This special issue belongs to the Section Biosignal Processing)

Applications of Partial Differential Equations in Bioengineering

edited by

José Alberto Rodrigues

and

Jacinta Serpa

submission deadline 30 Sep 2025 | Viewed by 1011 | Submission Open

Keywords: Partial Differential Equations; bioengineering modeling; mathematical biology; tissue engineering; biomechanics; biomedical imaging; fluid dynamics in biology; heat transfer in tissues; drug diffusion modeling; systems biology; epidemic modeling; mathematical models of physiological processes; numerical methods in bioengineering; biological signal processing; computational biology; multiscale modeling; mathematical modeling in regenerative medicine; multi-OMICs in health and disease

Artificial Intelligence and Nanotechnology in Cancer Therapy

edited by Wancheng Guo and

Aarti Sharma

submission deadline 30 Sep 2025 | Viewed by 592 | Submission Open

Keywords: AI; nanotechnology; cancer therapy

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Engineering Biomaterials for Regenerative Medicine Applications

edited by

Ramar Thangam

Heemin Kang

and Venugopal Krishnan

submission deadline 30 Sep 2025 | Viewed by 493 | Submission Open

Keywords: biomaterials; tissue repair; regenerative medicine; stem cells; immune cells; cancer therapy; biomedical devices and implants; tissue regeneration

(This special issue belongs to the Section Regenerative Engineering)

Design and Control Innovations in Prosthetic Hands: From Appearance to Advanced Functionality

edited by

Wenjun (Chris) Zhang

submission deadline 30 Sep 2025 | Viewed by 419 | Submission Open

Keywords: prosthetic hands; biomechanics; neural control systems; soft prosthetics; advanced materials; user-centered design; 3D printing in prosthetics; wireless control systems; mind-controlled prosthetics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Flexible Bioelectronics: Pioneering Innovations in Healthcare and Medicine

edited by George Luka and Sujung Kim

submission deadline 30 Sep 2025 | Viewed by 329 | Submission Open

Keywords: flexible bioelectronics; bioelectronics; biosensors; wearable microneedle biosensors; soft electronics; stretchable electronics; smart healthcare technologies

(This special issue belongs to the Section Biosignal Processing)

Multiscale Modeling in Computational Biomechanics: When Contemporary AI Meets Virtual Human Twin

edited by

Tien Tuan Dao

submission deadline 30 Sep 2025 | Viewed by 289 | Submission Open

Keywords: multiscale modeling; computational biomechanics; AI-driven biomechanics; virtual human twin; generative AI in medicine

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Reinforcement Learning and Neuromodulators: Bridging Neuroscience and Artificial Intelligence

edited by

Incheol Seo

and

Hyunsu Lee

submission deadline 30 Sep 2025 | Viewed by 270 | Submission Open

Keywords: reinforcement learning; neuromodulators; neuroscience; Artificial Intelligence (AI)

(This special issue belongs to the Section Biosignal Processing)

Three-Dimensional Printing in Modern Dentistry: State of the Art, Benefits and Future Prospects

edited by

Saverio Capodiferro

Massimo Corsalini

and

Giuseppe D'Albis

submission deadline 30 Sep 2025 | Viewed by 209 | Submission Open

Keywords: additive manufacturing; 3D printing; dentistry; CAD/CAM systems; biocompatible materials; clinical applications; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced Dental Materials for Restorative Dentistry

edited by

Feng Gao

submission deadline 30 Sep 2025 | 1 articles | Viewed by 198 | Submission Open

Keywords: denal restoration; restorative dentistry; dental biomaterials

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Advances in Artificial Intelligence Paradigms for the Detection and Diagnosis of Neurological Diseases

edited by

Yunfeng Wu

submission deadline 30 Sep 2025 | Viewed by 191 | Submission Open

Keywords: biomedical signal processing; artificial intelligence; data mining

(This special issue belongs to the Section Biosignal Processing)

Advanced Bioprocessing Approaches in Energy and Nutrient Recovery from Waste

edited by

Rajinikanth Rajagopal

and

Chunjiang An

submission deadline 30 Sep 2025 | Viewed by 163 | Submission Open

Keywords: anaerobic digestion; biogas production; biogas upgrading; hydrothermal carbonization; thermochemical processes; microbial communities; manure management; wastewater treatment; nutrient recovery; energy recovery; computational modeling; machine learning; circular economy; methane yield; nitrogen recovery; phosphorus recovery

(This special issue belongs to the Section Biochemical Engineering)

Biomaterial- and Engineering-Based Approaches for Organoids

edited by Xiuzhi Susan Sun

submission deadline 30 Sep 2025 | Viewed by 148 | Submission Open

Keywords: organoids; biomaterials; tissue engineering; three-dimensional bioprinting; microfluidics; extracellular matrix; disease modeling; regenerative medicine; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Novel Biomaterial Design and Strategies for Musculoskeletal Tissue Engineering

edited by

and

submission deadline 1 Oct 2025 | 3 articles | Viewed by 8750 | Submission Open

Keywords: biomaterials; bioprinting; tissue engineering; hydrogels; stem cells; orthopaedic surgery; musculoskeletal tissues; bone regeneration

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Computational Models in Cardiovascular System

edited by Ghassan S. Kassab

submission deadline 5 Oct 2025 | 9 articles | Viewed by 14752 | Submission Open

Keywords: biomechanics; heart; vessels; finite element analysis; artificial intelligence; machine learning; physics informed neural networks

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of AI in Biomedical Engineering for Healthy Ageing

edited by

Sai Kit Lam

submission deadline 5 Oct 2025 | 1 articles | Viewed by 1703 | Submission Open

Keywords: artificial intelligence in healthy aging; aging-associated diseases; cancer; deep learning; image segmentation and classification; machine learning; medical image analysis; personalized medicine; prognostication; risk stratification

(This special issue belongs to the Section Biosignal Processing)

Application of Convolutional Neural Networks in Bioimaging and Biosignal Processes

edited by

Sebelan Danishvar

and

Miguel Valencia

submission deadline 10 Oct 2025 | 4 articles | Viewed by 9800 | Submission Open

Keywords: biomedical image/signal analysis; biomedical image/signal processing; new AI architectures; detection and recognition in biomedical image/signals; automated/computer-aided diagnosis using convolutional neural networks

(This special issue belongs to the Section Biosignal Processing)

Advances in Thermal Therapy

edited by Aili Zhang and Kai Yue

submission deadline 15 Oct 2025 | 7 articles | Viewed by 15410 | Submission Open

Keywords: thermal treatments; thermal ablation; hyperthermia; cryosurgery; thermally enhanced treatment

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Inspired by Nature: Advanced Biomaterials and Manufacturing Solutions for Skeletal Tissue Regeneration and Osteoarthritis Treatment

edited by

Elena A. Jones

submission deadline 15 Oct 2025 | 4 articles | Viewed by 14801 | Submission Open

Keywords: bone and cartilage regeneration; osteoarthritis; immunomodulatory and infection-control biomaterials; bioactive matrices; microspheres; nanoparticles; bioinks; biomimetics; delivery methods

(This special issue belongs to the Section Regenerative Engineering)

Orthodontic Biomechanics

edited by Joanna Lis

submission deadline 15 Oct 2025 | 5 articles | Viewed by 7956 | Submission Open

Keywords: orthodontic biomechanics; skeletal anchorage; absolute anchorage

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Orthopedic and Trauma Biomechanics

edited by

Ligia Rusu

Nejc Šarabon

and

Mihnea Ion Marin

submission deadline 16 Oct 2025 | 1 articles | Viewed by 516 | Submission Open

Keywords: biomechanics; gait; trauma and biomechanics; movement; orthopedic assessment

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Recent Progress in Biomedical Image Processing and Analysis

edited by

Dildar Hussain

and

Jawad Khan

submission deadline 20 Oct 2025 | 3 articles | Viewed by 10058 | Submission Open

Keywords: biomedical imaging; image processing; image analysis; artificial intelligence; machine learning; medical diagnosis; precision medicine; healthcare technology

(This special issue belongs to the Section Biosignal Processing)

Machine Learning and Eye Movements: Insights into Learning and Autism Spectrum Disorders

edited by

Zoi Kapoula

and Alae Eddine El Hmimdi

submission deadline 20 Oct 2025 | 1 articles | Viewed by 905 | Submission Open

Keywords: eye movements; dyslexia; attention deficit disorders (ADDs); autism spectrum disorders (ASDs); learning disorders; artificial intelligence (AI); eye tracking technology; AI for early screening; explainable AI (XAI); anomaly detection

(This special issue belongs to the Section Biosignal Processing)

Biomedical Engineering Approaches for Non-Invasive Monitoring in Hypovolemia and Hypotension

edited by

Eric J. Snider

and

Victor A. Convertino

submission deadline 25 Oct 2025 | 1 articles | Viewed by 637 | Submission Open

Keywords: physiological monitoring; non-invasive monitoring; blood pressure estimation; advanced monitoring; machine learning; deep learning; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Novel Techniques in Meniscus Repair

edited by

Yuya Kodama

and

Yuki Okazaki

submission deadline 25 Oct 2025 | Viewed by 172 | Submission Open

Keywords: meniscus repair; arthroscopic surgery; meniscal root tear; biologic augmentation; knee joint preservation; meniscal healing; sports medicine; regenerative orthopedics

(This special issue belongs to the Section Regenerative Engineering)

Biomechanics and Motion Analysis

edited by

Christina Zong-Hao Ma

and

Hong Fu

submission deadline 31 Oct 2025 | 19 articles | Viewed by 28038 | Submission Open

Keywords: biomechanics; motion capture and analysis; sports and rehabilitation engineering; artificial intelligence; assistive technology

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advances in Additive Manufacturing Technologies in the Clinical, Pharmaceutical and Biomedical Sectors

edited by

Karthik K. Tappa

and

Udayabhanu Jammalamadaka

submission deadline 31 Oct 2025 | 11 articles | Viewed by 22600 | Submission Open

Keywords: 3D printing; bioprinting; bioactive materials; bioink; anatomical models; surgical guides; patient-specific implants; 3D-printed drug delivery systems; 3D-printed biomedical devices

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Medical Devices and Implants, 2nd Edition

edited by Tanvir Faisal, Christine Walck and Donald Sorrells

submission deadline 31 Oct 2025 | 10 articles | Viewed by 21779 | Submission Open

Keywords: implant; medical devices; prototyping; 3D printing; scaffolds; tissue engineering; additive manufacturing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Adaptive Neurostimulation: Innovative Strategies for Stimulation

edited by

Luca Mesin

submission deadline 31 Oct 2025 | 4 articles | Viewed by 14159 | Submission Open

Keywords: neurostimulation; closed-loop stimulation; adaptive stimulation; sustained attention; working memory; meditation; relaxation; stress; mindfulness; epilepsy; psychiatric disorders; ADHD; transcranial direct current stimulation; transcranial alternating current stimulation; binaural beats; light pulse stimulation; EEG; ECG; pupillogram; breath monitoring; real time processing; EEG rhythms; complexity; entropy; heart rate variability

(This special issue belongs to the Section Biosignal Processing)

Innovations in Regenerative Therapy: Cell and Cell-Free Approaches

edited by

Prakash Gangadaran

submission deadline 31 Oct 2025 | 4 articles | Viewed by 11189 | Submission Open

Keywords: cell-based therapies; MSCs; exosome; extracellular vesicles; bio nanovesicles; wound; ischemia; hair growth; brain; degenerative diseases

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

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