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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Progress in Biomedical Image Processing and Analysis

edited by

Dildar Hussain

and

Jawad Khan

submission deadline 20 Oct 2025 | 3 articles | Viewed by 11505 | Submission Open

Keywords: biomedical imaging; image processing; image analysis; artificial intelligence; machine learning; medical diagnosis; precision medicine; healthcare technology

(This special issue belongs to the Section Biosignal Processing)

Biomedical Engineering Approaches for Non-Invasive Monitoring in Hypovolemia and Hypotension

edited by

Eric J. Snider

and

Victor A. Convertino

submission deadline 25 Oct 2025 | 1 articles | Viewed by 754 | Submission Open

Keywords: physiological monitoring; non-invasive monitoring; blood pressure estimation; advanced monitoring; machine learning; deep learning; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Novel Techniques in Meniscus Repair

edited by

Yuya Kodama

and

Yuki Okazaki

submission deadline 25 Oct 2025 | Viewed by 214 | Submission Open

Keywords: meniscus repair; arthroscopic surgery; meniscal root tear; biologic augmentation; knee joint preservation; meniscal healing; sports medicine; regenerative orthopedics

(This special issue belongs to the Section Regenerative Engineering)

Biomechanics and Motion Analysis

edited by

Christina Zong-Hao Ma

and

Hong Fu

submission deadline 31 Oct 2025 | 22 articles | Viewed by 32248 | Submission Open

Keywords: biomechanics; motion capture and analysis; sports and rehabilitation engineering; artificial intelligence; assistive technology

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advances in Additive Manufacturing Technologies in the Clinical, Pharmaceutical and Biomedical Sectors

edited by

Karthik K. Tappa

and

Udayabhanu Jammalamadaka

submission deadline 31 Oct 2025 | 11 articles | Viewed by 28726 | Submission Open

Keywords: 3D printing; bioprinting; bioactive materials; bioink; anatomical models; surgical guides; patient-specific implants; 3D-printed drug delivery systems; 3D-printed biomedical devices

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Medical Devices and Implants, 2nd Edition

edited by Tanvir Faisal, Christine Walck and Donald Sorrells

submission deadline 31 Oct 2025 | 12 articles | Viewed by 23946 | Submission Open

Keywords: implant; medical devices; prototyping; 3D printing; scaffolds; tissue engineering; additive manufacturing

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Adaptive Neurostimulation: Innovative Strategies for Stimulation

edited by

Luca Mesin

submission deadline 31 Oct 2025 | 4 articles | Viewed by 15533 | Submission Open

Keywords: neurostimulation; closed-loop stimulation; adaptive stimulation; sustained attention; working memory; meditation; relaxation; stress; mindfulness; epilepsy; psychiatric disorders; ADHD; transcranial direct current stimulation; transcranial alternating current stimulation; binaural beats; light pulse stimulation; EEG; ECG; pupillogram; breath monitoring; real time processing; EEG rhythms; complexity; entropy; heart rate variability

(This special issue belongs to the Section Biosignal Processing)

Transforming Healthcare with Large Language Models: Innovations, Challenges, and Future Directions

edited by

Essam A. Rashed

, Walayat Hussain and

Ghada Khoriba

submission deadline 31 Oct 2025 | 2 articles | Viewed by 13152 | Submission Open

Keywords: large language models (LLMs); large vision models (LVMs); summarization of medical data; medical report generation; medical chatbots; healthcare data analysis; medical imaging; trustworthy AI; diagnosis

Innovations in Regenerative Therapy: Cell and Cell-Free Approaches

edited by

Prakash Gangadaran

submission deadline 31 Oct 2025 | 4 articles | Viewed by 11860 | Submission Open

Keywords: cell-based therapies; MSCs; exosome; extracellular vesicles; bio nanovesicles; wound; ischemia; hair growth; brain; degenerative diseases

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

AI Advancements in Healthcare: Medical Imaging and Sensing Technologies

edited by

Mohammed A. Al-masni

and Kanghyun Ryu

submission deadline 31 Oct 2025 | 6 articles | Viewed by 9193 | Submission Open

Keywords: biomedical imaging; biosignals; medical image analysis; abnormalities classification and detection; medical image segmentation; medical image reconstruction; medical image denoising; medical image registration; AI in biomedical systems; computer-aided diagnosis systems

(This special issue belongs to the Section Biosignal Processing)

Integrating Novel Therapeutics and Personalized Medicine into Osteoarthritis Treatment: Advancements in Cartilage Regeneration and Joint Preservation

edited by

Antonia Sun

submission deadline 31 Oct 2025 | 3 articles | Viewed by 8025 | Submission Open

Keywords: osteoarthritis; cartilage regeneration; personalized medicine; tissue engineering; stem cell therapy; gene therapy; biomaterials; molecular therapeutics; regenerative medicine; biomechanics; translational research; advanced imaging techniques; patient-specific therapies; inflammation modulation; bioinformatics; computational modeling

(This special issue belongs to the Section Regenerative Engineering)

Application of Bioengineering to Implant Dentistry

edited by Rolf Ewers and Umadevi Kandalam

submission deadline 31 Oct 2025 | 4 articles | Viewed by 7538 | Submission Open

Keywords: bioengineering; dental implantology; implant dentistry; dental biomaterials; surface modifications; biomechanics of implant integration; tissue engineering; biocompatibility; implant-associated infections

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence for Skin Diseases Classification

edited by Alessandra Cartocci and Linda Tognetti

submission deadline 31 Oct 2025 | 2 articles | Viewed by 5778 | Submission Open

Keywords: artificial intelligence; dermatology; skin diseases classification; machine learning; deep learning; computer vision; skin lesion detection; healthcare

(This special issue belongs to the Section Biosignal Processing)

Applications of Biomaterials in Dental Medicine

edited by

Alfredo De Rosa

submission deadline 31 Oct 2025 | 2 articles | Viewed by 4550 | Submission Open

Keywords: biomaterials; dental medicine; dental implants; orthodontics; oral health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomedical Applications of Multimodal Imaging Combined with Artificial Intelligence

edited by

Muhammad Umair Ali

submission deadline 31 Oct 2025 | 2 articles | Viewed by 4461 | Submission Open

Keywords: multimodal imaging; magnetic resonance imaging (MRI); computerized tomography (CT); positron emission tomography (PET); functional near-infrared spectroscopy (fNIRS); AI; EEG

(This special issue belongs to the Section Biosignal Processing)

Biomaterials for Angiogenesis

edited by Eva Dohle

submission deadline 31 Oct 2025 | 2 articles | Viewed by 3963 | Submission Open

Keywords: biomaterial; angiogenesis; vasculogenesis; tissue engineering; in vitro cell culture systems; tissue mimics; inflammation; growth factors; drug delivery

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence for Better Healthcare and Precision Medicine, 2nd Edition

edited by Yu Tian

submission deadline 31 Oct 2025 | 4 articles | Viewed by 2673 | Submission Open

Keywords: artificial intelligence; healthcare; precision medicine; disease diagnosis; prognosis; drug discovery; personalized treatment selection; healthcare resource management; large language models

(This special issue belongs to the Section Biosignal Processing)

Biomedical Imaging and Data Analytics for Disease Diagnosis and Treatment, 3rd Edition

edited by

Cosimo Ieracitano

and

Xuejun Zhang

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2656 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; biomedical engineering; medical image processing; data analytics

(This special issue belongs to the Section Biosignal Processing)

Explainable Artificial Intelligence (XAI) in Medical Imaging

edited by

Quincy A. Hathaway

and

Yashbir Singh

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2580 | Submission Open

Keywords: Explainable Artificial Intelligence (XAI); medical imaging; SHAP/LIME/Grad-CAM

(This special issue belongs to the Section Biosignal Processing)

Regenerative Rehabilitation for Spinal Cord Injury

edited by

Ajay Pal

, George Smith and Andrew J. Spence

submission deadline 31 Oct 2025 | 2 articles | Viewed by 2165 | Submission Open

Keywords: spinal cord injury; rehabilitation; neuromodulation; neural regeneration; neuroprotection; neuroplasticity; functional recovery; activity-based therapy; tissue engineering; neurotrophic factors

(This special issue belongs to the Section Regenerative Engineering)

Bioengineered Organs for Transplantation: Unveiling the Future of Organ Replacement

edited by Zhuolun Song

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2081 | Submission Open

Keywords: bioengineered organs; transplantation; regenerative medicine; tissue engineering; organ fabrication; biofabrication techniques; cellular reprogramming; biomaterials; bioreactor systems; preclinical testing

(This special issue belongs to the Section Regenerative Engineering)

New Technique for Endoscopic Diagnosis in Biomedical Engineering

edited by Changseok Bang

submission deadline 31 Oct 2025 | 1 articles | Viewed by 2040 | Submission Open

Keywords: endoscopic diagnosis; gastroenterology; novel technique; precision medicine; minimally invasive; patient- friendly; state-of-the-art technology; gastrointestinal disorders; diagnostic accuracy; research innovation

(This special issue belongs to the Section Biosignal Processing)

Advancements in Computational Modelling and Imaging Techniques for Personalised Treatment of Aortic Aneurysms

edited by

José Xavier

and

Simona Celi

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1739 | Submission Open

Keywords: cardiovascular diseases; silico modelling; computational fluid– structure interaction frameworks; advanced imaging techniques

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

AI-Driven Imaging and Analysis for Biomedical Applications

edited by Ulas Bagci,

Netzahualcoyotl Hernandez-Cruz

and

Zeyu Fu

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1654 | Submission Open

Keywords: biomedical image and video analysis; ultrasound-based image and video analysis; machine learning; multimodal imaging; AI-assisted diagnostics; real-time analysis; generative AI; explainable AI

(This special issue belongs to the Section Biosignal Processing)

Total Joint Arthroplasty: Technical Developments and Applications, 2nd Edition

edited by Armin Arshi

submission deadline 31 Oct 2025 | 2 articles | Viewed by 1466 | Submission Open

Keywords: arthroplasty; robotic assistance; periprosthetic; materials science; wear science; tissue engineering; tribology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Biomaterials for Oral Health Maintenance: A Translational Approach

edited by

Andrea Butera

and Cinzia Casu

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1239 | Submission Open

Keywords: biomaterial; oral health; translational medicine; dental care; caries; periodontitis; peri-implantitis; oral medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Engineering the Future of Radiotherapy: Innovations and Challenges

edited by

Kalliopi Platoni

and

Vassilis Kouloulias

submission deadline 31 Oct 2025 | 1 articles | Viewed by 1204 | Submission Open

Keywords: radiosurgery; stereotactic radiotherapy; proton therapy; artificial intelligence (AI); flash therapy; image/surface-guided radiotherapy; nanoparticles

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bio‑Derived Materials for Electrochemical Energy and Environmental Systems

edited by

Naoufel Haddour

submission deadline 31 Oct 2025 | 1 articles | Viewed by 996 | Submission Open

Keywords: bio‑sourced materials; biomass‑derived carbon; biopolymers; microbial fuel cells; supercapacitors; sustainable batteries; biochar electrodes; bio‑inspired catalysis

(This special issue belongs to the Section Biochemical Engineering)

Optical Imaging for Biomedical Applications, 2nd Edition

edited by

Johannes Dominikus Pallua

submission deadline 31 Oct 2025 | 1 articles | Viewed by 955 | Submission Open

Keywords: microscopy; digital pathology; infrared spectroscopy; Raman spectroscopy; NIR spectroscopy; hyperspectral imaging; combinations with MRI; X-ray; CT; or micro-CT; advanced imaging techniques and systems; imaging-guided surgery and treatment; artificial intelligence-based computational imaging techniques for biomedical imaging; image processing; photoacoustics; optical coherence tomography

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Sports Biomechanics and Injury Rehabilitation

edited by Yifei Yao

submission deadline 31 Oct 2025 | 1 articles | Viewed by 889 | Submission Open

Keywords: biomechanical analysis; injury prevention; rehabilitation techniques; sports performance; movement optimization

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Comprehensive Insights into Mechanical Circulatory Support in End-Stage Heart Failure

edited by Claudia Maria Loardi, Emmanuelle Vermes and Marco Zanobini

submission deadline 31 Oct 2025 | Viewed by 637 | Submission Open

Keywords: end-stage heart failure; cardiovascular engineering; cardiovascular technology; biomedical imaging; computational modeling; biventricular assistance; total artificial heart; left-ventricular assist device

(This special issue belongs to the Section Regenerative Engineering)

AI-Enhanced Biomechanics and Rehabilitation Engineering

edited by

Tarun Goswami

Anmar Salih

and

Farah Hamandi

submission deadline 31 Oct 2025 | Viewed by 627 | Submission Open

Keywords: artificial intelligence; biomechanics; rehabilitation engineering; machine learning; predictive modeling; prosthetic; gait analysis; personalized healthcare; biomechanical data analysis; injury prevention; fatigue detection; custom orthopedic solutions; biomechanical simulation; biomechanical performance; AI in biomechanical research

(This special issue belongs to the Section Biosignal Processing)

Therapeutic Solutions for Pain

edited by Farah Deba and

Olga Kopach

submission deadline 31 Oct 2025 | Viewed by 353 | Submission Open

Keywords: tissue engineering; cell therapy; drug discovery; chronic pain; biomaterials; drug delivery; nanotechnology; pain signaling

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Advancing Theranostics Through Photodynamic Therapy

edited by Taokun Luo and Wenyao Zhen

submission deadline 31 Oct 2025 | Viewed by 307 | Submission Open

Keywords: photodynamic therapy (PDT); theranostics; photosensitizers; light delivery systems; real-time imaging; targeted therapy; personalized medicine; translational research

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Interpretable Deep Learning for Object Detection and Medical Image Classification

edited by

Gurmail Singh

submission deadline 31 Oct 2025 | Viewed by 201 | Submission Open

Keywords: machine learning; deep learning; pattern recognition; neural networks; medical images; X-rays and CT-scan images; object detection and recognition; image segmentation; image classification

(This special issue belongs to the Section Biosignal Processing)

3D Bioprinting for Vascular Tissue Engineering

edited by

Vivian K. Lee

submission deadline 31 Oct 2025 | Viewed by 197 | Submission Open

Keywords: vascular tissue engineering; 3D bioprinting; bioinks; vascularization; angiogenesis; neovascularization; regenerative medicine; tissue constructs; disease modeling; drug screening

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Nanomaterial-Based Drug Delivery in Cancer Therapy

edited by

Venkata Krishna Kowthavarapu

Saurabh Sharma

and Mahipal Reddy Donthi

submission deadline 31 Oct 2025 | Viewed by 195 | Submission Open

Keywords: nanomaterial-based drug delivery; cancer therapy; nanomedicine; targeted drug delivery; nanoparticles (polymeric/liposomes/dendrimers); AI/ML in oncology; precision oncology; nanocarriers

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Application of Laser Therapy in Oral Diseases: Second Edition

edited by

Ivona Bago

and

Ivana Vidović Zdrilić

submission deadline 31 Oct 2025 | Viewed by 186 | Submission Open

Keywords: laser therapy; low-level laser therapy; photobiomodulation; oral diseases; laser parameters

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineering Intelligent Systems: From Robotic Manipulation to AI-Driven Healthcare Solutions

edited by

Tae-Seong Kim

submission deadline 31 Oct 2025 | Viewed by 170 | Submission Open

Keywords: intelligent robotics; medical AI; robotic manipulation; healthcare automation; machine learning in biomedicine; surgical robotics; Bio-inspired systems; AI-driven diagnostics.

(This special issue belongs to the Section Biosignal Processing)

Advanced Applications of Nanoparticles in Drug Delivery

edited by

Daoming Zhu

and

Pranothi Mulinti

submission deadline 31 Oct 2025 | Viewed by 169 | Submission Open

Keywords: targeted drug delivery; nanoparticles; disease-specific treatments; pharmacokinetics; nanoparticle design

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Applications of 3D Bioprinting Technology in Cancer Research

edited by

Aranzazu Villasante

submission deadline 31 Oct 2025 | Viewed by 159 | Submission Open

Keywords: 3D bioprinting; cancer models; tumor microenvironment; tissue engineering; personalized medicine

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Stem Cell Differentiation: From Mechanisms to Therapeutic Applications

edited by

Nasim Nosoudi

and Prabir Patra

submission deadline 31 Oct 2025 | Viewed by 154 | Submission Open

Keywords: stem cell differentiation; electrospinning; 3D bioprinting; biomaterials; regenerative medicine

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Artificial Intelligence in Cardio-Oncology and Cardiovascular Health

edited by Sherry Ann Brown

submission deadline 31 Oct 2025 | Viewed by 122 | Submission Open

Keywords: artificial intelligence; cardio-oncology; cardiovascular health; machine learning; personalized medicine; cardiovascular toxicity

(This special issue belongs to the Section Biosignal Processing)

Innovative Biomaterials and Advanced Technologies in Bone Tissue Regeneration

edited by

Natalia Di Pietro

submission deadline 1 Nov 2025 | 3 articles | Viewed by 3199 | Submission Open

Keywords: biomaterials; bone tissue regeneration; tissue engineering; scaffolds; prosthetics; dental implants; osseointegration; numerical studies; biomechanics; digital dentistry

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Stem Cell Engineering and Tissue Regeneration

edited by Bo Wang and

Shue Wang

submission deadline 1 Nov 2025 | Viewed by 421 | Submission Open

Keywords: stem cells; tissue engineering; biomaterial; drug delivery; clinical translation

(This special issue belongs to the Section Regenerative Engineering)

Nano-Based Drug Delivery System: Recent Developments and Future Prospects, Second Edition

edited by

Nitin Charbe

and

Venkata Krishna Kowthavarapu

submission deadline 10 Nov 2025 | Viewed by 93 | Submission Open

Keywords: nanomedicine; polymeric nanoparticles; siRNA delivery; mRNA delivery; lipid-based drug delivery systems; liposomes; targeted drug delivery systems; nanotherapeutics; biomaterials

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Innovations in Biomaterials for Advanced Biomedical Applications

edited by

Muhammad Zubair

and

Aman Ullah

submission deadline 15 Nov 2025 | 1 articles | Viewed by 2153 | Submission Open

Keywords: biomaterials; cancer treatment; wound care; cancer therapy; nanomedicine; drug delivery; tumor targeting; biocompatible materials; theranostics; immunotherapy; drug-release systems

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Machine Learning-Driven Innovations in Biomedical Signal and Image Processing

edited by