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  • Article
  • Open Access

Multi-Component Analysis of Protein- and DNA-Coated Magnetic Nanoparticles Using Electrochemical Impedance Spectroscopy with Interdigitated Electrode Sensors

  • Kestley Lutey,
  • Patrick B. White,
  • Hiram Cammon,
  • Miranda Trester,
  • Sue Brumfield,
  • John J. Neumeier,
  • Seth Pincus,
  • Robert W. Haushalter and
  • Joshua Heinemann
Bioengineering2025, 12(12), 1334;https://doi.org/10.3390/bioengineering12121334 
(registering DOI)

7 December 2025

The characterization of cancer and other diseases can be aided by the development of reusable electrochemical sensors that provide broad biomarker expression information in real time. We describe an interdigitated electrode (IDE) sensor array that ca...

  • Review
  • Open Access

A Comprehensive Review: The Bidirectional Role of Sebum in Skin Health

  • Dan Li,
  • Ziyan Zhou,
  • Xiaobin Yang,
  • Qirong Zhang,
  • Jiaming Xu,
  • Christos C. Zouboulis,
  • Qi Xiang and
  • Shu Zhang
Bioengineering2025, 12(12), 1333;https://doi.org/10.3390/bioengineering12121333 
(registering DOI)

6 December 2025

Sebum plays a dual role in skin homeostasis, maintaining barrier function and providing antimicrobial defense. However, its dysregulation drives the pathophysiology of common skin diseases. This review explains that abnormal sebum secretion promotes...

  • Article
  • Open Access
Bioengineering2025, 12(12), 1332;https://doi.org/10.3390/bioengineering12121332 
(registering DOI)

6 December 2025

Histopathological image classification using computational methods such as fine-tuned convolutional neural networks (CNNs) has gained significant attention in recent years. Graph neural networks (GNNs) have also emerged as strong alternatives, often...

  • Article
  • Open Access

Silymarin PlantCrystals for Improved Dermal Drug Delivery

  • Tehseen Sehra,
  • Muzn Alkhaldi and
  • Cornelia M. Keck

Background/Objectives: PlantCrystals (PCs) are submicron particles derived from plants or parts of plants that can be produced by bead milling and/or high-pressure homogenization. Previous studies suggested improved dermal drug delivery of lipophilic...

  • Article
  • Open Access

An Empirical Evaluation of Low-Rank Adapted Vision–Language Models for Radiology Image Captioning

  • Mahmudul Hoque,
  • Raisa Nusrat Chowdhury,
  • Md Rakibul Hasan,
  • Ojonugwa Oluwafemi Ejiga Peter,
  • Fahmi Khalifa and
  • Md Mahmudur Rahman

Rapidly growing medical imaging volumes have increased radiologist workloads, creating demand for automated tools that support interpretation and reduce reporting delays. Vision-language models (VLMs) can generate clinically relevant captions to acce...

  • Article
  • Open Access

Gastrointestinal Lesion Detection Using Ensemble Deep Learning Through Global Contextual Information

  • Vikrant Aadiwal,
  • Vishesh Tanwar,
  • Bhisham Sharma and
  • Dhirendra Prasad Yadav

The presence of subtle mucosal abnormalities makes small bowel Crohn’s disease (SBCD) and other gastrointestinal lesions difficult to detect, as these features are often very subtle and can closely resemble other disorders. Although the Kvasir...

  • Article
  • Open Access

The Stress–Strain State in the Pelvis During Sit-to-Stand Transfer

  • Urban Žnidaršič,
  • Andrej Žerovnik,
  • Matevž Tomaževič and
  • Robert Kunc

To achieve early mobilization of patients with unstable pelvic fractures, the osteosynthesis methods used must withstand the loads in the pelvis during everyday movements. There is currently no predictive tool to assess how suitable these methods are...

  • Article
  • Open Access
36 Views
14 Pages

Epileptic seizure (ES) detection is critical for improving clinical outcomes in epilepsy management. While intracranial EEG (iEEG) provides high-quality neural recordings, existing detection methods often rely on large amounts of data, involve high c...

  • Article
  • Open Access
30 Views
16 Pages

Serum tests are valuable sources of information for disease diagnosis. Conventional whole blood cell separation requires many processing steps, including centrifugation, fractionation, lysis, and dilution, and is therefore complex and time consuming....

  • Article
  • Open Access
62 Views
22 Pages

Image Captioning with Object Detection and Facial Expression Recognition for Smart Industry

  • Abdul Saboor Khan,
  • Abdul Haseeb Khan,
  • Muhammad Jamshed Abbass and
  • Imran Shafi

This paper presents a new image captioning system which contains facial expression recognition as a way to provide better emotional and contextual comprehension of the captions generated. A combination of affective cues and visual features is made, w...

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Bioengineering - ISSN 2306-5354