Toxics, Volume 13, Issue 12

Due to their wide application, there is a large amount of residual antibiotics in our environment and food, raising concerns about health risks to children. In this study, 302 primary-school students in Hainan Province, China, were recruited to colle...

(1) Background: Tobacco use constitutes a significant preventable cause of morbidity and mortality on a global scale. It contributes to cumulative exposure to carcinogenic and toxic heavy metals, including cadmium, lead, nickel, and copper. Collectiv...

Background: Drug-induced cardiotoxicity poses a major challenge in drug development and clinical safety. Although machine learning (ML) methods have shown potential in predicting cardiotoxic risks, prior research has largely focused on specific mecha...

This study investigated the occurrence, sources, and health risks of 16 polycyclic aromatic hydrocarbons (PAHs) in commonly consumed fish and crayfish from the Caohai Lake, a typical plateau lake in southwest China. Four dominant species (crucian car...

Recently, the environmental impact of halocarbons has become increasingly concerning, particularly due to the growing influence of non-regulated halocarbons on stratospheric ozone depletion and their adverse health effects in the troposphere. Previou...

This study evaluated the accumulation of heavy metals (As, Cd, Cu, Hg, Pb, and Zn) in Mediterranean mussels (Mytilus galloprovincialis) collected from five coastal stations (Küçükkumla, Kurşunlu, Güzelyalı, Mudanya, an...

Although the health risks associated with exposure to potentially harmful elements (PHEs) are well documented, there is still limited research on their accumulation at trace concentrations in small mammals inhabiting agricultural ecosystems. This stu...

Lead (Pb) pollution in wastewater is an immense problem for public health and the environment because it persists in the water bodies for a long period of time. Over the past years, many different techniques of Pb remediation have been discovered to...

Atmospheric fine particles (PM_2.5, aerodynamic diameter ≤ 2.5 µm) have a serious effect on human health. This study combined concentration weighted trajectory (CWT) analysis with the HYSPLIT trajectory ensemble (Ens-HYSPLIT-CWT), to separate...

Mt. Etna is the highest and most active stratovolcano in Europe, located in Catania (Sicily, Italy). Its persistent degassing, frequent explosions, and lava flows release large amounts of ash and gases into the atmosphere. This study aimed to assess...

Recent advances in agricultural biotechnology and sustainable farming have drawn attention to biochar as a multifunctional material for environmental remediation. Among its emerging applications, biochar has demonstrated remarkable potential in waste...

Sudden Unexplained Death (SUD) has been reported in specific regions of Yunnan Province, China, yet its environmental causes remain unclear. This study aimed to explore the potential toxicological link between trace element exposure and SUD by invest...

Persistent environmental pollutants such as per- and poly-fluoroalkyl substances (PFAS) have been associated with a wide range of toxic effects, including cancer. There are over 12,000 PFAS compounds, which may act as carcinogens individually or in c...

N-(1,3-Dimethylbutyl)-N’-phenyl-p-phenylenediamine (6PPD) is a member of the p-phenylenediamines (PPDs), recognized as a highly effective antioxidant. It has been extensively employed in the automotive tire manufacturing industry, and plays a c...

Pesticide pollution has become a major global issue, primarily because of its ability to induce widespread toxicity. This research aimed to explore the toxicological effects of Dufulin on zebrafish, focusing on the underlying molecular mechanisms of...

Heavy metal (HM) toxicity is one of the growing concerns, posing a significant threat to food security. Its trace presence in the food is one of the major reasons for considering it as a threat, which makes it potentially dangerous and a widespread c...

In recent years, the public environmental protection consciousness has improved regarding the source of drinking water. However, the risk status and sources of heavy metals (HMs) in the soil around drinking water sources remain unclear. The typical D...

The treatment of polychlorinated dibenzodioxins and polychlorinated dibenzofurans (PCDD/Fs) in incineration fly ash presents a significant challenge in solid hazardous waste management. This study systematically analyzed the influence mechanisms of m...

White-matter development during fetal life represents one of the most vulnerable processes to environmental disruption, as it relies on the precisely timed proliferation, migration, and differentiation of oligodendrocyte lineage cells. Among environm...

Microplastic distribution off the coast of Korea was investigated by collecting and analyzing surface seawater and sediment samples from the South Sea and East China Sea during the summer. Microplastic abundance was found to be highest in the YE area...

Heavy-metal contamination poses a significant global threat to soil environments, underscoring the necessity for effective and sustainable remediation technologies. This review methodically summarizes advances in the field of microbial remediation of...

Environmental contamination from industrial activities remains a significant concern, with tanneries being major contributors of chromium (Cr) to aquatic systems. Cr, a heavy metal with multiple oxidation states, varies in toxicity and poses risks to...

With the rapid development of urbanization, municipal waste incineration (MWI) has become the primary method of waste disposal in urban areas, leading to growing concerns about volatile organic compounds (VOC) emissions. This study conducted full-pro...

This study investigated the relationship between maternal barium (Ba) exposure and the risk of miscarriage using metabolomics and machine learning. Analyses were performed on samples from 183 pregnant women from Nanjing: the concentration of Ba in wh...

The development of new approach methodologies that include human cells differentiated into organotypic formats is of high interest due to their structural and functional similarities to tissues in vivo, enabling mechanistic understanding and translat...

Oxylipins are specialized lipid mediators that can have dual functions, either promoting inflammation or supporting resolution. Exposure to air pollution is associated with systemic inflammation that may be modified by oxylipins derived from polyunsa...

Environmental contamination with heavy metals, resulting from industrialization, urbanization, and agricultural intensification, poses serious ecological and health risks. Horses, due to their grazing behavior and close association with human environ...

Waste stone powder is a major solid waste byproduct of stone operations. This study developed a novel “alkali activation-calcination” process that efficiently converts waste stone powder into high-value-added silicon-based materials (SSM)...

Imidacloprid (IMI) and polystyrene microplastics (PS-MPs) are common environmental pollutants, posing potential risks to ecosystems and human health. However, there is limited research on their toxic effects on nerve cells, particularly under combine...

To understand the pulmonary function and main influencing factors of homemakers in rural Xi’an, a representative city in Northwest China, 72 housewives (61 ± 9 years old) were randomly selected from the rural area of Lantian, Xi’an...

High-nitrogen organic chemical wastewater is characterized by high chemical oxygen demand (COD_Cr), poor biodegradability, and toxic nitrogenous organics, posing significant challenges for conventional biological treatment. In this study, a dual-elect...

Neonicotinoid insecticides (NNIs) are globally pervasive, and toxicological evidence indicates potential adverse effects from low-dose exposure in non-targeted organisms. Humans may be exposed to NNIs through multiple pathways, such as ingestion and...

In honeybees (Apis mellifera L.), the queen ensures the reproduction of the colony. Environmental contamination that could alter this function could compromise the survival of the colony. Ionizing radiation could be such a factor, but its effects hav...

Cadmium (Cd) and other trace elements represent a significant global environmental and public health concern due to their persistence, bioaccumulation potential, and widespread distribution in ecosystems [...]

Fetal exposure to toxic metals is a major public health concern, yet the contribution of intrauterine blood transfusion (IUBT) to this exposure remains unclear. This prospective cohort study assessed mercury, cadmium, lead, and arsenic levels in mate...

Poly Ether-Ether Ketone (PEEK) is used in modified atmosphere packaging (MAP) for fruit and vegetable preservation, but raises health concerns. This study investigated the effects of PEEK food migrations on liver cell mitochondrial damage. Food simul...

Gas flaring from upstream oil and gas production remains a significant source of air pollution and toxic emissions, with major implications for human health and climate. However, the number of people living near flaring has not been quantified global...

Agricultural intensification in greenhouse systems leads to a substantial accumulation of pesticides, yet its role in reshaping soil microbial interactions and their network stability remains poorly understood. This study reveals a critical ecologica...

The COVID-19 pandemic emerging in early 2020 triggered global responses. In China, stringent lockdown measures were implemented to suppress the rapid spread of infection, resulting in substantial reductions in anthropogenic emissions. However, severa...

Papermaking sludge, rich in intrinsic resource value, is effectively barred from direct deployment in environmental remediation, agriculture, or energy generation by its pronounced contaminant burden. Pyrolytic conversion into high-value paper sludge...

Cadmium (Cd) is a persistent toxic metal that bioaccumulates in human tissues and may disrupt redox and endocrine pathways, yet the metabolic mechanisms linking Cd exposure to both endothelial and prostate dysfunctions remain insufficiently defined....

The rapid growth in manufacturing and use of electrical and electronic equipment has led to unprecedented volumes of poorly managed e-waste, posing serious ecological risks. Although data on individual chemical substances in e-waste are available, ev...

Cadmium (Cd) accumulation in rice poses a serious threat to global food safety and human health. Foliar application of nano-silica (Si) offers a promising remediation strategy, but its efficacy is often limited by poor droplet retention on hydrophobi...

With the increasing global burden of major depressive disorder (MDD), identifying modifiable environmental risk factors has become a critical priority. Per- and polyfluoroalkyl substances (PFASs), characterized by environmental persistence and bioacc...

Microplastics (MPs) have become widespread environmental contaminants, with increasing evidence of their harmful impacts on human health. MPs generally enter the human body via ingestion, inhalation, or dermal exposure, with the gastrointestinal trac...

Soil co-contamination with heavy metals (HMs) and polycyclic aromatic hydrocarbons (PAHs) represents a widespread and challenging environmental issue that is difficult to address using conventional remediation methods. This review systematically exam...

Antidepressant drugs (ADDs) are one of the most widely prescribed pharmaceuticals globally and are widely detected in the environment. They are designed to target monoamine neurotransmission—a highly conserved pathway between humans and animal...

Cu in tea leaves can be easily leached into the tea broth during brewing and ingested by humans; therefore, excessive accumulation of Cu in tea leaves may pose potential health risks. In this study, the relationship between soil Cu and Cu content in...

The pervasive environmental contamination by microplastics (MPs) and per- and polyfluoroalkyl substances (PFAS) represents a critical challenge of the Anthropocene. While historically studied in isolation, a growing body of evidence confirms that the...

Building upon a theoretical framework, this study utilized 126 field survey questionnaires from farmers in Shouyang County, Shanxi Province, China, coupled with corresponding farmland soil heavy metal monitoring data, to investigate the extent of hea...