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Toxics, Volume 13, Issue 12

December 2025 - 85 articles

Cover Story: The growing co-occurrence of nanomaterials and conventional pollutants poses pressing questions regarding their combined ecological impacts. The findings presented in this study confirm that titanium dioxide nanoparticles (n-TiO2) function as a potent carrier of ammonia nitrogen, significantly enhancing its accumulation in zebrafish embryos. This synergistic interaction exacerbates developmental neurotoxicity, characterized by profound behavioral deficits and increased neuronal apoptosis. Notably, co-exposure disrupts both key neurotransmitter systems and critical neurodevelopmental pathways. These findings highlight n-TiO2 as a toxicity enhancer of conventional pollutants and underscore the necessity of integrated risk assessment for combined environmental exposures. View this paper
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Articles (85)

  • Article
  • Open Access
342 Views
16 Pages

Antibiotic Exposure in School Children in Tropical Environments: Impact of Dietary Habits and Potential Health Risks

  • Lin Zhao,
  • Xin-Yu Wang,
  • Yang Xiang,
  • Ting-Ting Xu,
  • Shi-Jian Liu,
  • Xiao-Ya Lin and
  • Ying Guo

18 December 2025

Due to their wide application, there is a large amount of residual antibiotics in our environment and food, raising concerns about health risks to children. In this study, 302 primary-school students in Hainan Province, China, were recruited to colle...

  • Article
  • Open Access
425 Views
20 Pages

Toxic Trace Element Concentration in Commercially Available Cigarettes in Poland, Europe

  • Małgorzata Ćwieląg-Drabek,
  • Joanna Domagalska,
  • Marta Buczkowska and
  • Agata Piekut

18 December 2025

(1) Background: Tobacco use constitutes a significant preventable cause of morbidity and mortality on a global scale. It contributes to cumulative exposure to carcinogenic and toxic heavy metals, including cadmium, lead, nickel, and copper. Collectiv...

  • Systematic Review
  • Open Access
593 Views
24 Pages

Machine Learning for Predicting Human Drug-Induced Cardiotoxicity: A Scoping Review

  • Ja-Young Han,
  • Min Jung Kim,
  • Hyunwoo Kim,
  • KeunOh Choi,
  • Seongjin Ju and
  • Myeong Gyu Kim

17 December 2025

Background: Drug-induced cardiotoxicity poses a major challenge in drug development and clinical safety. Although machine learning (ML) methods have shown potential in predicting cardiotoxic risks, prior research has largely focused on specific mecha...

  • Article
  • Open Access
387 Views
17 Pages

Composition, Sources, and Health Risks of Polycyclic Aromatic Hydrocarbons in Commonly Consumed Fish and Crayfish from Caohai Lake, Southwest China

  • Yupei Hao,
  • Tianyao Yang,
  • Xueqin Wei,
  • Xu Zhang,
  • Xiongyi Miao,
  • Gaohai Xu,
  • Sheping Yang,
  • Xiaohua Zhou,
  • Huifang Zhao and
  • Wei Bao

17 December 2025

This study investigated the occurrence, sources, and health risks of 16 polycyclic aromatic hydrocarbons (PAHs) in commonly consumed fish and crayfish from the Caohai Lake, a typical plateau lake in southwest China. Four dominant species (crucian car...

  • Article
  • Open Access
332 Views
21 Pages

Temporal Evolution, Source Apportionment, and Health Risks of Atmospheric Halocarbons: A Case Study in the Central Yangtze River Delta Region

  • Yuchun Jiang,
  • Anqi Zhang,
  • Qiaoli Zou,
  • Hanfei Zuo,
  • Jinmei Ding,
  • Lu Zhang,
  • Lingling Jin,
  • Da Xu,
  • Yuwen Niu and
  • Bingye Xu
  • + 1 author

17 December 2025

Recently, the environmental impact of halocarbons has become increasingly concerning, particularly due to the growing influence of non-regulated halocarbons on stratospheric ozone depletion and their adverse health effects in the troposphere. Previou...

  • Article
  • Open Access
599 Views
18 Pages

17 December 2025

This study evaluated the accumulation of heavy metals (As, Cd, Cu, Hg, Pb, and Zn) in Mediterranean mussels (Mytilus galloprovincialis) collected from five coastal stations (Küçükkumla, Kurşunlu, Güzelyalı, Mudanya, an...

  • Article
  • Open Access
305 Views
14 Pages

Bioaccumulation of Potential Harmful Elements in Fossorial Water Voles Inhabiting Non-Polluted Crops

  • Aitor Somoano,
  • Roser Adalid,
  • Jacint Ventura,
  • Francesc Muñoz-Muñoz,
  • Màrius Vicent Fuentes,
  • Mario Menéndez-Miranda and
  • Marcos Miñarro

16 December 2025

Although the health risks associated with exposure to potentially harmful elements (PHEs) are well documented, there is still limited research on their accumulation at trace concentrations in small mammals inhabiting agricultural ecosystems. This stu...

  • Review
  • Open Access
376 Views
32 Pages

Comprehensive Review of Microbial, Plant, Biochar, Mineral, and Nanomaterial Solutions for Lead-Contaminated Wastewater

  • Aminur Rahman,
  • Md Azizul Haque,
  • Md Mahbubur Rahman,
  • Pottathil Shinu,
  • Muhammad Muhitur Rahman,
  • Aftab Ahmad Khan and
  • Sayeed Rushd

16 December 2025

Lead (Pb) pollution in wastewater is an immense problem for public health and the environment because it persists in the water bodies for a long period of time. Over the past years, many different techniques of Pb remediation have been discovered to...

  • Article
  • Open Access
564 Views
13 Pages

Source-Specific PM2.5 Exposure and Associated Health Risks During Beijing Winter

  • Xin Liu,
  • Zhiqing Liu,
  • Wenming Pei,
  • Xiaoyu Zhang,
  • Xiaoting Jie,
  • Zhi Yang,
  • Liwei Liu,
  • Yuxing Gao,
  • Ruoyu Hu and
  • Mingzhu Zhang

16 December 2025

Atmospheric fine particles (PM2.5, aerodynamic diameter ≤ 2.5 µm) have a serious effect on human health. This study combined concentration weighted trajectory (CWT) analysis with the HYSPLIT trajectory ensemble (Ens-HYSPLIT-CWT), to separate...

  • Article
  • Open Access
394 Views
19 Pages

Human Exposure to Metals and Potential Human Health Risk in a Volcanic Environment in Italy

  • Giovanni Forte,
  • Venerando Rapisarda,
  • Flavia Ruggieri,
  • Beatrice Battistini,
  • Lisa Bauleo,
  • Veronica Filetti,
  • Elena Grignani,
  • Piero Lovreglio,
  • Serena Matera and
  • Paola Senia
  • + 4 authors

15 December 2025

Mt. Etna is the highest and most active stratovolcano in Europe, located in Catania (Sicily, Italy). Its persistent degassing, frequent explosions, and lava flows release large amounts of ash and gases into the atmosphere. This study aimed to assess...

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Toxics - ISSN 2305-6304