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Current Oncology, Volume 31, Issue 10

October 2024 - 56 articles

Cover Story: Most clinical practice guidelines recommend shared decision making on PSA screening for prostate cancer, following a discussion of its benefits and disadvantages. However, there are limited data on the opinions of the general male population on these topics. We surveyed an online cohort of 906 adult men regarding their knowledge, opinions, and attitudes about prostate cancer and PSA screening, revealing some surprising perspectives: most adult men thought it was worth screening 10,000 patients with blood tests to reduce the chance of 1 man dying of prostate cancer. A number of prevalent misconceptions were also uncovered, supporting the role of clinicians in informing their patients and engaging in prostate cancer screening discussions. View this paper
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Articles (56)

  • Article
  • Open Access
1 Citations
3,380 Views
30 Pages

Assessing the Impact of the Prostate Cancer Patient Empowerment Program (PC-PEP) on Relationship Satisfaction, Quality of Life, and Support Group Participation: A Randomized Clinical Trial

  • Cory Burgher,
  • Gabriela Ilie,
  • Ross Mason,
  • Ricardo Rendon,
  • Andrea Kokorovic,
  • Greg Bailly,
  • Nikhilesh Patil,
  • David Bowes,
  • Derek Wilke and
  • Cody MacDonald
  • + 5 authors

21 October 2024

Background/Objectives: The Prostate Cancer Patient Empowerment Program (PC-PEP) is a 6-month, home-based intervention aimed at enhancing mental health in men undergoing curative prostate cancer treatment. This exploratory secondary analysis evaluates...

  • Review
  • Open Access
3 Citations
2,028 Views
12 Pages

Clinical Insights and Future Prospects: A Comprehensive Narrative Review on Immunomodulation Induced by Electrochemotherapy

  • Martina Ferioli,
  • Anna Myriam Perrone,
  • Pierandrea De Iaco,
  • Arina A. Zamfir,
  • Gloria Ravegnini,
  • Milly Buwenge,
  • Bruno Fionda,
  • Erika Galietta,
  • Costanza M. Donati and
  • Luca Tagliaferri
  • + 1 author

21 October 2024

Electrochemotherapy (ECT) is an emerging therapeutic approach gaining growing interest for its potential immunomodulatory effects in cancer treatment. This narrative review systematically examines the current state of knowledge regarding the interpla...

  • Article
  • Open Access
3 Citations
2,877 Views
14 Pages

Effects of Immersive Virtual Therapy as a Method Supporting the Psychological and Physical Well-Being of Women with a Breast Cancer Diagnosis: A Randomized Controlled Trial

  • Oliver Czech,
  • Aleksandra Kowaluk,
  • Tomasz Ściepuro,
  • Katarzyna Siewierska,
  • Jakub Skórniak,
  • Rafał Matkowski and
  • Iwona Malicka

21 October 2024

This study aimed to evaluate the effectiveness of virtual reality (VR) in the mental state and quality of sleep improvement and physical activity (PA) increase of patients diagnosed with breast cancer (BC). A total of 33 subjects divided into experim...

  • Article
  • Open Access
2 Citations
1,916 Views
13 Pages

Lack of Association Between BsmI and FokI Polymorphisms of the VDR Gene and Sporadic Colorectal Cancer in a Romanian Cohort—A Preliminary Study

  • Bianca Petre-Mandache,
  • Emilia Burada,
  • Mihai Gabriel Cucu,
  • Diter Atasie,
  • Anca-Lelia Riza,
  • Ioana Streață,
  • Radu Mitruț,
  • Răzvan Pleșea,
  • Amelia Dobrescu and
  • Andrei Pîrvu
  • + 3 authors

21 October 2024

Colorectal cancer (CRC) is a major public health problem worldwide, currently ranking third in cancer incidence and second in mortality. Multiple genes and environmental factors have been involved in the complex and multifactorial process of CRC carc...

  • Article
  • Open Access
1 Citations
1,942 Views
11 Pages

Perspectives and Misconceptions of an Online Adult Male Cohort Regarding Prostate Cancer Screening

  • Tyler Sheetz,
  • Tasha Posid,
  • Aliza Khuhro,
  • Alicia Scimeca,
  • Sarah Beebe,
  • Essa Gul and
  • Shawn Dason

20 October 2024

Introduction: Congruent with most guideline publishers, the Canadian Urological Association (CUA) recommends shared decision-making (SDM) on PSA screening (PSAS) for prostate cancer (PCa) following a discussion of its benefits and harms. However, the...

  • Article
  • Open Access
1 Citations
1,620 Views
11 Pages

Can Patient Characteristics and Pre-Treatment MRI Features Predict Survival After Stereotactic Ablative Radiotherapy (SABR) Treatment in Hepatocellular Carcinoma (HCC): Preliminary Assessment

  • Rachel Gravell,
  • Russell Frood,
  • Anna Littlejohns,
  • Nathalie Casanova,
  • Rebecca Goody,
  • Christine Podesta,
  • Raneem Albazaz and
  • Andrew Scarsbrook

19 October 2024

Background: The study purpose was to develop a machine learning (ML)-based predictive model for event-free survival (EFS) in patients with hepatocellular carcinoma (HCC) undergoing stereotactic ablative radiotherapy (SABR). Methods: Patients receivin...

  • Review
  • Open Access
8 Citations
11,410 Views
28 Pages

Managing Select Immune-Related Adverse Events in Patients Treated with Immune Checkpoint Inhibitors

  • Parneet K. Cheema,
  • Marco A. J. Iafolla,
  • Husam Abdel-Qadir,
  • Andrew B. Bellini,
  • Nazira Chatur,
  • Natasha Chandok,
  • Vikram R. Comondore,
  • Morven Cunningham,
  • Ilana Halperin and
  • Anne B. Hu
  • + 8 authors

18 October 2024

The increased use of immune checkpoint inhibitors (ICIs) across cancer programs has created the need for standardized monitoring and management of immune-related adverse events (irAEs). Delayed recognition without appropriate treatment can have serio...

  • Article
  • Open Access
2 Citations
2,059 Views
13 Pages

18 October 2024

Hyperprogressive disease (HPD) is described as the unexpected rapid growth of a tumour accompanied by a decline in performance status. While immune checkpoint inhibitors (ICIs) have improved outcomes in advanced melanoma, HPD remains a significant ch...

  • Review
  • Open Access
3 Citations
6,861 Views
29 Pages

Antibody–Drug Conjugates for the Treatment of Non-Small Cell Lung Cancer with Central Nervous System Metastases

  • David J. H. Bian,
  • Sara F. Cohen,
  • Anna-Maria Lazaratos,
  • Nathaniel Bouganim and
  • Matthew Dankner

18 October 2024

Antibody–drug conjugates (ADCs) represent an emerging class of targeted anticancer agents that have demonstrated impressive efficacy in numerous cancer types. In non-small cell lung cancer (NSCLC), ADCs have become a component of the treatment...

  • Systematic Review
  • Open Access
1,978 Views
14 Pages

The Importance of Patient-Reported Outcome Measures (PROMs) in Oncological Vulvoperineal Defect Reconstruction: A Systematic Review

  • Nicole E. Speck,
  • Julia Stoffel,
  • Séverin Wendelspiess,
  • Christian Appenzeller-Herzog,
  • Kristin M. Schaefer,
  • Loraine P. Kouba,
  • Florian Rüter,
  • Céline Montavon,
  • Viola Heinzelmann-Schwarz and
  • Martin D. Haug
  • + 3 authors

18 October 2024

Background: Patient-reported outcome measures (PROMs) have gained increased importance in assessing outcomes after reconstructive surgery. This also applies to the reconstruction of vulvoperineal defects after resection of gynecological or colorectal...

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Curr. Oncol. - ISSN 1718-7729