Mar. Drugs, Volume 16, Issue 12 (December 2018) – 60 articles
Cover Story (view full-size image): Collagen is the most abundant structural protein in vertebrates, found in skin, bones and cartilage, among other tissues, with a pivotal role in the maintenance of their biological and structural integrity. Collagen is thus a key building block in biomaterials design for tissue engineering and regeneration. Conventionally, collagen has porcine or bovine origin, which present some ethical and safety constrains, and marine species have been presented as a sustainable alternative, particularly when considering fish processing industry by-products. In the highlighted work, collagen type I was isolated from codfish skins and, despite the lower denaturation temperature, the high purity extracts enable the production of collagen coating supporting the culture of human fibroblast cell line, with promising biomedical application. View this paper.
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