Cytotoxic Sesterterpenes from Thai Marine Sponge Hyrtios erectus
AbstractFour sesterterpenes, erectusolides B, C, D, and seco-manoalide-25-methyl ether, two 2-furanone derivatives, erectusfuranones A and B, together with thirteen known sesterterpenes, (6Z)-neomanoalide-24-acetate, two diastereomers of 24-O-methylmanoalide, luffariolide B, manoalide, (6E)- and (6Z)-neomanoalide, seco-manoalide, scalarafuran, 12-acetylscalarolide, 12-epi-O-deacetyl-19-deoxyscalarin, 12-epi-scalarin, and 12-O-deacetyl-12-epi-scalarin, three indole alkaloids, 5-hydroxy-1H-indole-3-carbaldehyde, hyrtiosine A, and variabine B, and one norterpene, cavernosine were isolated from the marine sponge Hyrtios erectus. Their structures were determined by means of spectroscopic methods and the absolute configurations of the asymmetric centers were determined using the modified Mosher’s method. The cytotoxic activities for the isolated compounds have been reported. View Full-Text
- Supplementary File 1:
PDF-Document (PDF, 10768 KB)
Share & Cite This Article
Kaweetripob, W.; Mahidol, C.; Tuntiwachwuttikul, P.; Ruchirawat, S.; Prawat, H. Cytotoxic Sesterterpenes from Thai Marine Sponge Hyrtios erectus. Mar. Drugs 2018, 16, 474.
Kaweetripob W, Mahidol C, Tuntiwachwuttikul P, Ruchirawat S, Prawat H. Cytotoxic Sesterterpenes from Thai Marine Sponge Hyrtios erectus. Marine Drugs. 2018; 16(12):474.Chicago/Turabian Style
Kaweetripob, Wirongrong; Mahidol, Chulabhorn; Tuntiwachwuttikul, Pittaya; Ruchirawat, Somsak; Prawat, Hunsa. 2018. "Cytotoxic Sesterterpenes from Thai Marine Sponge Hyrtios erectus." Mar. Drugs 16, no. 12: 474.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.