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Molecules, Volume 22, Issue 4

April 2017 - 174 articles

Cover Story: The figure showed in the cover describes the action of barbatic acid from the lichen Cladia Aggregata, occured in the Brazilian northeast, against Embryos and Snails of Biomphalaria Glabrata (Vector of Schistosomiasis), as well as its cercaricidae activity. View the paper
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Articles (174)

  • Article
  • Open Access
28 Citations
7,067 Views
17 Pages

Inhibitory Effect of Triterpenoids from Panax ginseng on Coagulation Factor X

  • Lingxin Xiong,
  • Zeng Qi,
  • Bingzhen Zheng,
  • Zhuo Li,
  • Fang Wang,
  • Jinping Liu and
  • Pingya Li

Enzymes involved in the coagulation process have received great attention as potential targets for the development of oral anti-coagulants. Among these enzymes, coagulation factor Xa (FXa) has remained the center of attention in the last decade. In t...

  • Article
  • Open Access
112 Citations
12,294 Views
13 Pages

Previously, we found that phenolic content and antioxidant capacity (AOX) in carrots increased with wounding intensity. It was also reported that UV radiation may trigger the phenylpropanoid metabolism in plant tissues. Here, we determined the combin...

  • Review
  • Open Access
28 Citations
11,409 Views
18 Pages

Fourteen well-defined ribozyme classes have been identified to date, among which nine are site-specific self-cleaving ribozymes. Very recently, small self-cleaving ribozymes have attracted renewed interest in their structure, biochemistry, and biolog...

  • Article
  • Open Access
39 Citations
6,956 Views
16 Pages

The present study was conducted to screen a laccase-producing fungal endophyte, optimize fermentation conditions, and evaluate the decolorization ability of the laccase. A new fungal endophyte capable of laccase-producing was firstly isolated from pi...

  • Article
  • Open Access
9 Citations
5,935 Views
10 Pages

Many agonists for the estrogen receptor are known to disrupt endocrine functioning. We have developed a computational model that predicts agonists for the estrogen receptor ligand-binding domain in an assay system. Our model was entered into the Tox2...

  • Review
  • Open Access
174 Citations
21,569 Views
18 Pages

The inhibitory adenosine A1 receptor (A1R) and excitatory A2A receptor (A2AR) are predominantly expressed in the brain. Whereas the A2AR has been implicated in normal aging and enhancing neurotoxicity in multiple neurodegenerative diseases, the inhib...

  • Feature Paper
  • Article
  • Open Access
113 Citations
10,817 Views
19 Pages

Particles of sub-micron size possess significant capacity to adsorb organic molecules from aqueous media. Semiconductor photocatalysts in particle form could potentially be utilized for dye removal through either physical adsorption or photo-induced...

  • Article
  • Open Access
40 Citations
8,325 Views
14 Pages

Phenolic Compounds Isolated from Caesalpinia coriaria Induce S and G2/M Phase Cell Cycle Arrest Differentially and Trigger Cell Death by Interfering with Microtubule Dynamics in Cancer Cell Lines

  • Jessica Nayelli Sánchez-Carranza,
  • Laura Alvarez,
  • Silvia Marquina-Bahena,
  • Enrique Salas-Vidal,
  • Verónica Cuevas,
  • Elizabeth W. Jiménez,
  • Rafael A. Veloz G.,
  • Maelle Carraz and
  • Leticia González-Maya

Caesalpinia coriaria (C. coriaria), also named cascalote, has been known traditionally in México for having cicatrizing and inflammatory properties. Phytochemical reports on Caesalpinia species have identified a high content of phenolic compounds and...

  • Article
  • Open Access
6 Citations
5,635 Views
16 Pages

Multiple UDP-Glucuronosyltransferase and Sulfotransferase Enzymes are Responsible for the Metabolism of Verproside in Human Liver Preparations

  • Ju-Hyun Kim,
  • Deok-Kyu Hwang,
  • Ju-Yeon Moon,
  • Yongnam Lee,
  • Ji Seok Yoo,
  • Dae Hee Shin and
  • Hye Suk Lee

Verproside, an active iridoid glycoside component of Veronica species, such as Pseudolysimachion rotundum var. subintegrum and Veronica anagallis-aquatica, possesses anti-asthma, anti-inflammatory, anti-nociceptive, antioxidant, and cytostatic activi...

  • Review
  • Open Access
223 Citations
15,715 Views
24 Pages

Polyphenolic Compounds and Digestive Enzymes: In Vitro Non-Covalent Interactions

  • Alejandra I. Martinez-Gonzalez,
  • Ángel G. Díaz-Sánchez,
  • Laura A. de la Rosa,
  • Claudia L. Vargas-Requena,
  • Ismael Bustos-Jaimes and
  • And Emilio Alvarez-Parrilla

The digestive enzymes–polyphenolic compounds (PCs) interactions behind the inhibition of these enzymes have not been completely studied. The existing studies have mainly analyzed polyphenolic extracts and reported inhibition percentages of catalytic...

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Molecules - ISSN 1420-3049